Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 17, 2000, Pages 9677-9682

  DeBarber, Andrea E ^a   Mdluli, Khisimuzi ^a   Bosman, Marlein ^b   Bekker, Linda Gail ^b   Barry III, Clifton E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CARBON 14; CATALASE; DRUG METABOLITE; ETHIONAMIDE; ISONIAZID; METHANOL DERIVATIVE; PEROXIDASE; REGULATOR PROTEIN; THIOACETAZONE; THIOAMIDE; TIOCARLIDE; TUBERCULOSTATIC AGENT; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; CROSS RESISTANCE; DRUG ACTIVATION; DRUG METABOLISM; DRUG OXIDATION; DRUG SENSITIVITY; DRUG SYNTHESIS; ENZYME REGULATION; HUMAN; ISOTOPE LABELING; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SOUTH AFRICA; TARGET CELL; TUBERCULOSIS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0034662963     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.17.9677     Document Type: Article

References (46)

1. Farmer, P., Bayona, J., Becerra, M., Furin, J., Henry, C., Hiatt, H., Kim, J. Y., Mitnick, C., Nardell, E. & Shin, S. (1998) Int. J. Tuberc. Lung Dis. 2, 869-876.
2. Viskum, K. & Kok-Jensen, A. (1997) Int. J. Tuberc. Lung Dis. 1, 299-301.
3. Bass, J. B., Jr., Farer, L. S., Hopewell, P. C., O'Brien, R., Jacobs, R. F., Ruben, F., Snider, D. E., Jr. & Thornton, G. (1994) Am. J. Respir. Crit. Care Med. 149, 1359-1374.
4. W. H. O. (1996) TB: Groups at Risk, WHO Report on the Tuberculosis Epidemic (World Health Organization, Geneva).
5. Crofton, J., Chaulet, P., Maher, D., Grosset, J., Harris, W., Norman, H., Iseman, M. & Watt, B. (1997) Guidelines for the Management of Multidrug-Resistant Tuberculosis (World Health Organization, Geneva).
6. Barry, C. E., 3rd, Slayden, R. A., Sampson, A. E. & Lee, R. E. (2000) Biochem. Pharmacol. 59, 221-231.
7. Slayden, R. A. & Barry, C. E., 3rd (2000) Microbes Infect. 6, 1-11.
8. Johnsson, K. & Schultz, P. G. (1994) J. Am. Chem. Soc. 116, 7425-7426.
9. Rozwarski, D. A., Grant, G. A., Barton, D. H. R., Jacobs, W. R., Jr. & Sacchettini, J. C. (1998) Science 279, 98-102.
10. Banerjee, A., Dubnau, E., Quemard, A., Balasubramanian, V., Um, K. S., Wilson, T., Collins, D., Lisle, G. D. & Jacobs, W. R., Jr. (1994) Science 263, 227-230.
11. Wilming, M. & Johnsson, K. (1999) Angew. Chem. Int. Ed. 38, 2588-2590.
12. Youatt, J. (1960) Aust. J. Exp. Biol. Med. Sci. 38, 245-250.
13. Youatt, J. (1961) Aust. J. Chem. 14, 308-311.
14. Youatt, J. (1969) Am. Rev. Respir. Dis. 99, 729-749.
15. Musser, J. M. (1995) Clin. Microbiol. Rev. 8, 496-514.
16. Rist, N. (1960) Adv. Tuberc. Res. 10, 69-126.
17. Johnsson, K., King, D. S. & Schultz, P. G. (1995) J. Am. Chem. Soc. 117, 5009-5010.
18. Bieder, A., Brunel, P., Roquet-Ghaye, J. & Kries, B. (1966) Rev. Fra. Etud. Clin. Biol. 11, 419-423.
19. Johnston, J. P., Kane, P. O. & Kibby, M. R. (1967) J. Pharm. Pharmacol. 19, 1-9.
20. Grunert, M. & Iwainsky, H. (1967) Arzneim. Forsch. 17, 411-415.
21. Prema, K. & Gopinthan, K. P. (1976) J. Indian Inst. Sci. 58, 16-27.
22. Bonicke, R. (1965) Beitr. Klin. Erforsch. Tububerk. Lungenkrankh. 132, 311-314.
23. Stevens, G. J., Hitchcock, K., Wang, Y. K., Coppola, G. M., Versace, R. W., Chin, J. A., Shapiro, M., Suwanrumpha, S. & Mangold, B. L. K. (1997) Chem. Res. Toxicol. 10, 733-741.
24. Kucherova, N. F., Khomutov, R. M., Budovskii, E. I., Evadakov, V. P. & Kochetkov, N. K. (1959) Zhurnal Obshchei Khimii 29, 915-919.
25. Gutekunst, G. O. & Gray, H. L. (1922) J. Am. Chem. Soc. 44, 1741-1746.
26. Lawrie, K. W. M., Novellie, C. E. A., Saunders, D. & Coates, W. J. (1995) J. Labeled Compounds Radiopharm. 36, 891-898.
27. Sunay, U. B., Talbot, K., Prasad, K., Lee, G. & Jones, L. (1995) J. Labeled Compound Radiopharm. 36, 529-536.
28. Meinert, M. C., Nunez, H. A. & Byerrum, R. U. (1978) J. Labeled Compounds Radiopharm. 14, 893-896.
29. Walter, W. & Curts, J. (1960) Chem. Ber. 93, 1511-1515.
30. Mdluli, K., Sherman, D. R., Hickey, M. J., Kreiswirth, B. N., Morris, S., Stover, C. K. & Barry, C. E., 3rd (1996) J. Infect. Dis. 174, 1085-1090.
31. George, K. M., Yuan, Y., Sherman, D. R. & Barry, C. E., 3rd (1995) J. Biol. Chem. 270, 27292-27298.
32. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., 3rd, et al. (1998) Nature (London) 393, 537-544.
33. Chen, Y. C., Peoples, O. P. & Walsh, C. T. (1988) J. Bacteriol. 170, 781-789.
34. White, O., Eisen, J. A., Heidelberg, J. F., Hickey, E. K., Peterson, J. D., Dodson, R. J., Haft, D. H., Gwinn, M. L., Nelson, W. C., Richardson, D. L., et al. (1999) Science 286, 1571-1577.
35. Redenbach, M., Kieser, H. M., Denapaite, D., Eichner, A., Cullum, J., Kinashi, H. & Hopwood, D. A. (1996) Mol. Microbiol. 21, 77-96.
36. Zhang, Y., Heym, B., Allen, B., Young, D. & Cole, S. (1992) Nature (London) 358, 591-593.
37. Nelson, D. R. (1999) Arch. Biochem. Biophys. 369, 1-10.
38. Nunn, P., Porter, J. & Winstanley, P. (1993) Trans. R. Soc. Trop. Med. Hyg. 87, 578-582.
39. Phetsuksiri, B., Baulard, A. R., Cooper, A. M., Minnikin, D. E., Douglas, J. D., Besra, G. S. & Brennan, P. J. (1999) Antimicrob. Agents Chemother. 43, 1042-1051.
40. Muzikravic, T. (1970) Antibiot. Chemother. 16, 177-181.
41. Sojkova, M., Tousek, J. & Trnka, L. (1965) Praxis Pneumol. Vereinigt Tuberk. 19, 522-527.
42. Murohashi & Yanagisawa (1963) Acta Tuberc. Pneumol. Belg. 54, 35-40.
43. Tskamura, M. (1962) Kekkaku 37, 103-113.
44. Afanasieva, Y. P. & Mkrtchyan, S. V. (1969) Probl. Tuberk. 47, 66-99.
45. Verbist, L. (1965) Antimicrob. Agents Chemother. 5, 298-305.
46. Konopka, E., Gisi, T. & Eisman, P. (1955) Proc. Soc. Exp. Biol. 89, 388-398.