Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

Biochemistry

Volumn 38, Issue 38, 1999, Pages 12514-12525

  Ward, Walter H J ^a   Holdgate, Geoffrey A ^a   Rowsell, Siân ^a   McLean, Estelle G ^a   Pauptit, Richard A ^a   Clayton, Edward ^a   Nichols, Wright W ^a   Colls, Jeremy G ^a   Minshull, Claire A ^a   Jude, David A ^a   Mistry, Anil ^a   Timms, David ^a   Camble, Roger ^a   Hales, Neil J ^a   Britton, Carolyn J ^a   Taylor, Ian W F ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRICLOSAN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

ANTI-INFECTIVE AGENTS, LOCAL; BINDING, COMPETITIVE; CATALYSIS; CHROMATOGRAPHY, GEL; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); ENZYME INHIBITORS; ESCHERICHIA COLI PROTEINS; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; NAD; OXIDOREDUCTASES; STRUCTURE-ACTIVITY RELATIONSHIP; TRICLOSAN;

EID: 0033592365     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9907779     Document Type: Article

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