Novel therapeutic targets in lung cancer: Inhibitor of apoptosis proteins from laboratory to clinic

Cancer Treatment Reviews

Volumn 33, Issue 2, 2007, Pages 203-212

  Dean, Emma J ^a   Ranson, Malcolm ^a   Blackhall, Fiona ^a   Holt, Sarah V ^b   Dive, Caroline ^b  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Antisense; Apoptosis; Inhibitors of apoptosis; Non small cell lung cancer; Small cell lung cancer; Small molecules; X linked inhibitor of apoptosis protein

Indexed keywords

AEG 35156; ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; CASPASE 7; CASPASE 9; CASPASE INHIBITOR; CISPLATIN; DOXORUBICIN; ETOPOSIDE; GEMCITABINE; INHIBITOR OF APOPTOSIS PROTEIN; LIGASE INHIBITOR; LY 2181308; NAVELBINE; NEURONAL APOPTOSIS INHIBITORY PROTEIN; PEPTIDE DERIVATIVE; PLATINUM COMPLEX; PROTEIN INHIBITOR; PROTEIN KINASE B INHIBITOR; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI; SURVIVIN; TAXANE DERIVATIVE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; YM 155;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; APOPTOSIS; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURVIVAL; CAUSE OF DEATH; CELL PROLIFERATION; CIGARETTE SMOKING; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTINUOUS INFUSION; DRUG RESEARCH; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MONOTHERAPY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; TREATMENT FAILURE; TREATMENT OUTCOME; TUMOR VOLUME;

APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; CASPASES; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LUNG NEOPLASMS;

EID: 33847301497     PISSN: 03057372     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ctrv.2006.11.002     Document Type: Review

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