Apaf-1/Cytochrome c-independent and Smac-dependent Induction of Apoptosis in Multiple Myeloma (MM) Cells

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 24453-24456

  Chauhan, Dharminder ^a   Hideshima, Teru ^a   Rosen, Steven ^b   Reed, John C ^c   Kharbanda, Surender ^a   Anderson, Kenneth C ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c BURNHAM INSTITUTE   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; PROTEINS;

APOPTOSIS; OLIGOMERIZATION;

BIOCHEMISTRY;

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 9; CYTOCHROME C; DEXAMETHASONE; GROWTH FACTOR; INTERLEUKIN 6; PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; APAF1 PROTEIN, HUMAN; BIRC4 PROTEIN, HUMAN; CARRIER PROTEIN; CASP9 PROTEIN, HUMAN; DIABLO PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; SIGNAL PEPTIDE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; CELL CULTURE; METABOLISM;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CARRIER PROTEINS; CASPASE 9; CASPASES; CYTOCHROME C GROUP; CYTOSOL; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; MULTIPLE MYELOMA; PROTEINS; TUMOR CELLS, CULTURED; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 0035816553     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100074200     Document Type: Article

References (29)

1. Willie, A. H., Kerr, J. F., and Currie, A. R. (1980) Int. Rev. Cytol. 68, 251-306
2. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
3. Chinnaiyan, A. M., and Dixit, V. M. (1996) Curr. Biol. 6, 555-562
4. Oberhammer, F. A., Hochegger, K., Froschl, G., Tiefenbacher, R., and Pavelka, M. (1994) J. Cell Biol. 126, 827-837
5. Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. (1994) Nature 371, 346-347
6. Emoto, Y., Manome, Y., Meinhardt, G., Kisaki, H., Kharbanda, S., Robertson, M., Ghayur, T., Wong, W. W., Kamen, R., Weichselbaum, R., and Kufe, D. (1995) EMBO J. 14, 6148-6156
7. Deveraux, Q. L., and Reed, J. C. (1999) Genes Dev. 13, 239-252
8. Miller, L. K. (1999) Trends Cell Biol. 9, 323-328
9. Deveraux, Q. L., Roy, N., Stennicke, H. R., Van Arsdale, T., Zhou, Q., Srinivasula, S. M., Alnemri, E. S., Salvesen, G. S., and Reed, J. C. (1998) EMBO J. 17, 2215-2223
10. Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C. (1997) EMBO J. 16, 6914-6925
11. Liu, X., Naekyung Kim, C., Yang, J., Jemmerson, R., and Wang, X. (1996) Cell 86, 147-157
12. Yang, J., Liu, X., Balla, K., Kim, C. N., Ibardo, N. M., Cai, J., Peng, T. i., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1136
13. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) Science 275, 1132-1136
14. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 479-489
15. Zou, H., Li, Y., Liu, X., and Wang, X. (1999) J. Biol. Chem. 274, 11549-11556
16. Hu, Y., Ding, L., Spencer, D. M., and Nunez, G. (1998) J. Biol. Chem. 273, 33489-33494
17. Bossy-Wetzel, E., and Green, D. R. (1999) Mutat. Res. 434, 243-251
18. Chai, J., Du, C., Wu, J. W., Kyin, S., Wang, X., and Shi, Y. (2000) Nature 406, 855-862
19. Srinivasula, S. M., Datta, P., Fan, X. J., Fernandes-Alnemri, T., Huang, Z., and Alnemri, E. S. (2000) J. Biol. Chem. 275, 36152-36157
20. Du, C., Fang, M., Li, Y., Li, L., and Wang, X. (2000) Cell 102, 33-42
21. Verhagen, A. M., Ekert, P. G., Pakusch, M., Silke, J., Connolly, L. M., Reid, G. E., Moritz, R. L., Simpson, R. J., and Vaux, D. L. (2000) Cell 102, 43-53
22. Chauhan, D., Pandey, P., Ogata, A., Teoh, G., Krett, N., Halgren, R., Rosen, S., Kufe, D., Kharbanda, S., and Anderson, K. C. (1997) J. Biol. Chem. 272, 29995-29997
23. Chauhan, D., Pandey, P., Ogata, A., Teoh, G., Treon, S., Urashima, M., Kharbanda, S., and Anderson, K. C. (1997) Oncogene 15, 837-843
24. Chauhan, D., Pandey, P., Hideshima, T., Treon, S., Raje, N., Davies, F. E., Shima, Y., Tai, Y.-T., Rosen, S., Avraham, S., Kharbanda, S., and Anderson, K. C. (2000) J. Biol. Chem. 275, 27845-27850
25. Pandey, P., Saleh, A., Nakazawa, A., Kumar, S., Srinivasula, S. M., Kumar, V., Weichselbaum, R., Nalin, C., Alnemri, E. S., Kufe, D., and Kharbanda, S. (2000) EMBO J. 19, 4310-4322
26. Mesner, P. W., Bible, K. C., Martins, L. M., Kottke, T. J., Srinivasula, S. M., Svingen, P. A., Chilcote, T. J., Basi, G. S., Tung, J. S., Krajeewski, S., Reed, J. C., Alnemri, E. S., Earnshaw, W. C., and Kaufmann, S. H. (1999) J. Biol. Chem. 274, 22635-22645
27. Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C. (1997) Nature 388, 300-304
28. Chauhan, D., and Anderson, K. C. (2001) Apoptosis 6, 47-55
29. Klein, B., Zhang, X. G., Lu, Z. Y., and Battaille, R. (1995) Blood 85, 863-872