-
1
-
-
32944464648
-
-
Akira, S., Uematsu, S. & Takeuchi, O. Pathogen recognition and innate immunity. Cell 124, 783-801 (2006). A comprehensive review of TLR biology.
-
Akira, S., Uematsu, S. & Takeuchi, O. Pathogen recognition and innate immunity. Cell 124, 783-801 (2006). A comprehensive review of TLR biology.
-
-
-
-
2
-
-
3142691844
-
The road to Toll
-
Lemaitre, B. The road to Toll. Nature Rev. Immunol. 4, 521-527 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 521-527
-
-
Lemaitre, B.1
-
3
-
-
0030831210
-
-
Medzhitov, R., Preston-Hurlburt, P. & Janeway, C. A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388, 394-397 (1997). A pioneering report describing Toll-like signalling molecules in a higher vertebrate.
-
Medzhitov, R., Preston-Hurlburt, P. & Janeway, C. A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388, 394-397 (1997). A pioneering report describing Toll-like signalling molecules in a higher vertebrate.
-
-
-
-
4
-
-
0030595339
-
-
Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J. M. & Hoffmann, J. A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983 (1996). Characterization of the role of Toll in resistance to pathogens of D. melanogaster.
-
Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J. M. & Hoffmann, J. A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983 (1996). Characterization of the role of Toll in resistance to pathogens of D. melanogaster.
-
-
-
-
5
-
-
28444459897
-
How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals
-
Fritz, J. H. & Girardin, S. E. How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals. J. Endotoxin Res. 11, 390-394 (2005).
-
(2005)
J. Endotoxin Res
, vol.11
, pp. 390-394
-
-
Fritz, J.H.1
Girardin, S.E.2
-
6
-
-
0012929728
-
Toll-like receptors
-
Takeda, K., Kaisho, T. & Akira, S. Toll-like receptors. Annu. Rev. Immunol. 21, 335-376 (2003).
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
7
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin, I. R., Leadbetter, E. A., Busconi, L., Viglianti, G. & Marshak-Rothstein, A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol. Rev. 204, 27-42 (2005).
-
(2005)
Immunol. Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
8
-
-
11844275910
-
Ligand recognition by antigen-presenting cell C-type lectin receptors
-
McGreal, E. P., Miller, J. L. & Gordon, S. Ligand recognition by antigen-presenting cell C-type lectin receptors. Curr. Opin. Immunol. 17, 18-24 (2005).
-
(2005)
Curr. Opin. Immunol
, vol.17
, pp. 18-24
-
-
McGreal, E.P.1
Miller, J.L.2
Gordon, S.3
-
9
-
-
33244497571
-
Dectin-1: A signalling non-TLR pattern-recognition receptor
-
Brown, G. D. Dectin-1: a signalling non-TLR pattern-recognition receptor. Nature Rev. Immunol. 6, 33-43 (2006).
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 33-43
-
-
Brown, G.D.1
-
10
-
-
33745847180
-
TLRs, NLRs and RLRs: A trinity of pathogen sensors that co-operate in innate immunity
-
Creagh, E. M. & O'Neill, L. A. TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity. Trends Immunol. 27, 352-357 (2006).
-
(2006)
Trends Immunol
, vol.27
, pp. 352-357
-
-
Creagh, E.M.1
O'Neill, L.A.2
-
11
-
-
5444262511
-
-
Iwasaki, A. & Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nature Immunol. 5, 987-995 (2004). This paper describes the differential expresssion of TLRs by different antigen-presenting cells.
-
Iwasaki, A. & Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nature Immunol. 5, 987-995 (2004). This paper describes the differential expresssion of TLRs by different antigen-presenting cells.
-
-
-
-
12
-
-
33746161021
-
+ lamina propria cells
-
+ lamina propria cells. Nature Immunol. 7, 868-874 (2006).
-
(2006)
Nature Immunol
, vol.7
, pp. 868-874
-
-
Uematsu, S.1
-
13
-
-
0034750461
-
Synergy between TLR2 and TLR4: A safety mechanism
-
Beutler, E., Gelbart, T. & West, C. Synergy between TLR2 and TLR4: a safety mechanism. Blood Cells Mol. Dis. 27, 728-730 (2001).
-
(2001)
Blood Cells Mol. Dis
, vol.27
, pp. 728-730
-
-
Beutler, E.1
Gelbart, T.2
West, C.3
-
14
-
-
0034671772
-
-
Sato, S. et al. Synergy and cross-tolerance between toll-like receptor (TLR)2- and TLR4-mediated signaling pathways. J. Immunol. 165, 7096-7101 (2000). References 13 and 14 are early reports of cooperation between TLRs.
-
Sato, S. et al. Synergy and cross-tolerance between toll-like receptor (TLR)2- and TLR4-mediated signaling pathways. J. Immunol. 165, 7096-7101 (2000). References 13 and 14 are early reports of cooperation between TLRs.
-
-
-
-
15
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin, S. E. et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278, 8869-8872 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
-
16
-
-
4143131229
-
-
Whitmore, M. M. et al. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res. 64, 5850-5860 (2004). The first study to describe the use of multiple TLR ligands to increase host resistance.
-
Whitmore, M. M. et al. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res. 64, 5850-5860 (2004). The first study to describe the use of multiple TLR ligands to increase host resistance.
-
-
-
-
17
-
-
18644364701
-
A type I interferon autocrine - paracrine loop is involved in Toll-like receptor-induced interleukin-12 p70 secretion by dendritic cells
-
Gautier, G. et al. A type I interferon autocrine - paracrine loop is involved in Toll-like receptor-induced interleukin-12 p70 secretion by dendritic cells. J. Exp. Med. 201, 1435-1446 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 1435-1446
-
-
Gautier, G.1
-
18
-
-
23944489407
-
-
Napolitani, G., Rinaldi, A., Bertoni, F., Sallusto, F. & Lanzavecchia, A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nature Immunol. 6, 769-776 (2005). References 17 and 18 are the first reports to describe the strong synergistic effects of TLR ligands on IL-12 p70 production by DCs.
-
Napolitani, G., Rinaldi, A., Bertoni, F., Sallusto, F. & Lanzavecchia, A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nature Immunol. 6, 769-776 (2005). References 17 and 18 are the first reports to describe the strong synergistic effects of TLR ligands on IL-12 p70 production by DCs.
-
-
-
-
19
-
-
10344243503
-
-
H1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J. Immunol. 173, 7548-7555 (2004). One of the early studies showing differential and antagonistic functional consequences of the activation of different TLRs.
-
H1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J. Immunol. 173, 7548-7555 (2004). One of the early studies showing differential and antagonistic functional consequences of the activation of different TLRs.
-
-
-
-
20
-
-
23644449245
-
The expression of Toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of Toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells
-
Roelofs, M. F. et al. The expression of Toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of Toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum. 52, 2313-2322 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2313-2322
-
-
Roelofs, M.F.1
-
21
-
-
0030064148
-
The interleukin 12 p40 gene promoter is primed by interferon-? in monocytic cells
-
Ma, X. et al. The interleukin 12 p40 gene promoter is primed by interferon-? in monocytic cells. J. Exp. Med. 183, 147-157 (1996).
-
(1996)
J. Exp. Med
, vol.183
, pp. 147-157
-
-
Ma, X.1
-
22
-
-
0036786447
-
Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering
-
Edwards, A. D. et al. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering. J. Immunol. 169, 3652-3660 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 3652-3660
-
-
Edwards, A.D.1
-
23
-
-
33745865224
-
T-cell control of IL-12p75 production
-
Abdi, K., Singh, N. & Matzinger, P. T-cell control of IL-12p75 production. Scand. J. Immunol. 64, 83-92 (2006).
-
(2006)
Scand. J. Immunol
, vol.64
, pp. 83-92
-
-
Abdi, K.1
Singh, N.2
Matzinger, P.3
-
24
-
-
33744919288
-
T cell-independent, TLR-induced IL-12p70 production in primary human monocytes
-
Bekeredjian-Ding, I. et al. T cell-independent, TLR-induced IL-12p70 production in primary human monocytes. J. Immunol. 176, 7438-7446 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 7438-7446
-
-
Bekeredjian-Ding, I.1
-
25
-
-
11244336489
-
Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein
-
Liu, J., Guan, X., Tamura, T., Ozato, K. & Ma, X. Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein. J. Biol. Chem. 279, 55609-55617 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55609-55617
-
-
Liu, J.1
Guan, X.2
Tamura, T.3
Ozato, K.4
Ma, X.5
-
26
-
-
20144382923
-
Toll-like receptor signaling stimulates cell cycle entry and progression in fibroblasts
-
Hasan, U. A., Trinchieri, G. & Vlach, J. Toll-like receptor signaling stimulates cell cycle entry and progression in fibroblasts. J. Biol. Chem. 280, 20620-20627 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20620-20627
-
-
Hasan, U.A.1
Trinchieri, G.2
Vlach, J.3
-
27
-
-
0033697454
-
CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
-
Schulz, O. et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 13, 453-462 (2000).
-
(2000)
Immunity
, vol.13
, pp. 453-462
-
-
Schulz, O.1
-
28
-
-
33846207958
-
-
MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists, A recent report documenting synergy between MyD88- and TRIF-dependent signalling by TLR agonists
-
Bagchi, A. et al. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J. Immunol. 178, 1164-1171 (2007). A recent report documenting synergy between MyD88- and TRIF-dependent signalling by TLR agonists.
-
(2007)
J. Immunol
, vol.178
, pp. 1164-1171
-
-
Bagchi, A.1
-
29
-
-
29144434113
-
H1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
-
H1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J. Exp. Med. 202, 1715-1724 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1715-1724
-
-
Bafica, A.1
-
30
-
-
33748477504
-
-
Bafica, A. et al. Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. J. Immunol. 177, 3515-3519 (2006). The first description of TLR cooperation in host defence against a protozoan pathogen.
-
Bafica, A. et al. Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. J. Immunol. 177, 3515-3519 (2006). The first description of TLR cooperation in host defence against a protozoan pathogen.
-
-
-
-
31
-
-
33646908228
-
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
-
Kagan, J. C. & Medzhitov, R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125, 943-955 (2006).
-
(2006)
Cell
, vol.125
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
32
-
-
0038605053
-
Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages
-
Rhee, S. H., Jones, B. W., Toshchakov, V., Vogel, S. N. & Fenton, M. J. Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. J. Biol. Chem. 278, 22506-22512 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 22506-22512
-
-
Rhee, S.H.1
Jones, B.W.2
Toshchakov, V.3
Vogel, S.N.4
Fenton, M.J.5
-
33
-
-
33748690758
-
Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3
-
Dahlberg, A., Auble, M. R. & Petro, T. M. Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3. Virology 353, 422-432 (2006).
-
(2006)
Virology
, vol.353
, pp. 422-432
-
-
Dahlberg, A.1
Auble, M.R.2
Petro, T.M.3
-
34
-
-
17844380477
-
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
-
Honda, K. et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 434, 1035-1040 (2005).
-
(2005)
Nature
, vol.434
, pp. 1035-1040
-
-
Honda, K.1
-
35
-
-
20644450804
-
Negative regulation of Toll-like receptor-mediated immune responses
-
Liew, F. Y., Xu, D., Brint, E. K. & O'Neill, L. A. Negative regulation of Toll-like receptor-mediated immune responses. Nature Rev. Immunol. 5, 446-458 (2005).
-
(2005)
Nature Rev. Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
36
-
-
23844508543
-
Synergistic enhancement of Toll-like receptor responses by NOD1 activation
-
van Heel, D. A. et al. Synergistic enhancement of Toll-like receptor responses by NOD1 activation. Eur. J. Immunol. 35, 2471-2476 (2005).
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 2471-2476
-
-
van Heel, D.A.1
-
37
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz, J. H. et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur. J. Immunol. 35, 2459-2470 (2005).
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
-
38
-
-
12444259829
-
Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture
-
Uehara, A. et al. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture. Cell. Microbiol. 7, 53-61 (2005).
-
(2005)
Cell. Microbiol
, vol.7
, pp. 53-61
-
-
Uehara, A.1
-
39
-
-
28444471235
-
Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
-
Tada, H., Aiba, S., Shibata, K., Ohteki, T. & Takada, H. Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect. Immun. 73, 7967-7976 (2005).
-
(2005)
Infect. Immun
, vol.73
, pp. 7967-7976
-
-
Tada, H.1
Aiba, S.2
Shibata, K.3
Ohteki, T.4
Takada, H.5
-
40
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe, T., Kitani, A., Murray, P. J. & Strober, W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nature Immunol. 5, 800-808 (2004).
-
(2004)
Nature Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
41
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K. S. et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307, 731-734 (2005).
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
-
42
-
-
27444433978
-
NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease
-
Watanabe, T., Kitani, A. & Strober, W. NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease. Gut 54, 1515-1518 (2005).
-
(2005)
Gut
, vol.54
, pp. 1515-1518
-
-
Watanabe, T.1
Kitani, A.2
Strober, W.3
-
43
-
-
27444444603
-
Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease
-
van Heel, D. A. et al. Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease. Gut 54, 1553-1557 (2005).
-
(2005)
Gut
, vol.54
, pp. 1553-1557
-
-
van Heel, D.A.1
-
44
-
-
33244472793
-
Signalling pathways and molecular interactions of NOD1 and NOD2
-
Strober, W., Murray, P. J., Kitani, A. & Watanabe, T. Signalling pathways and molecular interactions of NOD1 and NOD2. Nature Rev. Immunol. 6, 9-20 (2006).
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 9-20
-
-
Strober, W.1
Murray, P.J.2
Kitani, A.3
Watanabe, T.4
-
45
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan, S. et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430, 213-218 (2004).
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
-
46
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini, L. et al. NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319-325 (2004).
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
-
47
-
-
1642380180
-
Unraveling the NALP-3/IL-1β inflammasome: A big lesson from a small mutation
-
Dinarello, C. A. Unraveling the NALP-3/IL-1β inflammasome: a big lesson from a small mutation. Immunity 20, 243-244 (2004).
-
(2004)
Immunity
, vol.20
, pp. 243-244
-
-
Dinarello, C.A.1
-
48
-
-
33846014297
-
Critical role for Cryopyrin/ Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti, T. D. et al. Critical role for Cryopyrin/ Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J. Biol. Chem. 281, 36560-36568 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
-
49
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala, F. S. et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24, 317-327 (2006).
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
-
50
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S. et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232 (2006).
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
-
51
-
-
33747191203
-
The inflammasome: First line of the immune response to cell stress
-
Ogura, Y., Sutterwala, F. S. & Flavell, R. A. The inflammasome: first line of the immune response to cell stress. Cell 126, 659-662 (2006).
-
(2006)
Cell
, vol.126
, pp. 659-662
-
-
Ogura, Y.1
Sutterwala, F.S.2
Flavell, R.A.3
-
52
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon, F., Petrilli, V., Mayor, A., Tardivel, A. & Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237-241 (2006).
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
53
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin-1β in salmonella-infected macrophages
-
Franchi, L. et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin-1β in salmonella-infected macrophages. Nature Immunol. 7, 576-582 (2006).
-
(2006)
Nature Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
-
54
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin-1β via Ipaf
-
Miao, E. A. et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin-1β via Ipaf. Nature Immunol. 7, 569-575 (2006).
-
(2006)
Nature Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
-
55
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H. et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006).
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
-
56
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin, L. et al. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl Acad. Sci. USA 103, 8459-8464 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
-
57
-
-
0036216769
-
Phagocytosis of microbes: Complexity in action
-
Underhill, D. M. & Ozinsky, A. Phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20, 825-852 (2002).
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 825-852
-
-
Underhill, D.M.1
Ozinsky, A.2
-
58
-
-
30044450421
-
Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages
-
Pathak, S. K. et al. Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages. J. Biol. Chem. 280, 42794-42800 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 42794-42800
-
-
Pathak, S.K.1
-
59
-
-
33751176262
-
The β-glucan receptor Dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria
-
Yadav, M. & Schorey, J. S. The β-glucan receptor Dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria. Blood 108, 3168-3175 (2006).
-
(2006)
Blood
, vol.108
, pp. 3168-3175
-
-
Yadav, M.1
Schorey, J.S.2
-
60
-
-
20244363662
-
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C-type lectins
-
Rogers, N. C. et al. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C-type lectins. Immunity 22, 507-517 (2005).
-
(2005)
Immunity
, vol.22
, pp. 507-517
-
-
Rogers, N.C.1
-
61
-
-
33845456631
-
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors
-
Netea, M. G. et al. Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. J. Leukocyte Biol. 80, 1454-1461 (2006).
-
(2006)
J. Leukocyte Biol
, vol.80
, pp. 1454-1461
-
-
Netea, M.G.1
-
62
-
-
1842424642
-
Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: Differential regulation of activation and survival
-
Radsak, M. P., Salih, H. R., Rammensee, H. G. & Schild, H. Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: differential regulation of activation and survival. J. Immunol. 172, 4956-4963 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 4956-4963
-
-
Radsak, M.P.1
Salih, H.R.2
Rammensee, H.G.3
Schild, H.4
-
63
-
-
33748517428
-
Cutting edge: TREM-2 attenuates macrophage activation
-
Turnbull, I. R. et al. Cutting edge: TREM-2 attenuates macrophage activation. J. Immunol. 177, 3520-3524 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 3520-3524
-
-
Turnbull, I.R.1
-
64
-
-
33746875981
-
Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
-
Hamerman, J. A. et al. Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J. Immunol. 177, 2051-2055 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 2051-2055
-
-
Hamerman, J.A.1
-
65
-
-
0035313284
-
Suppression of IL-12 transcription in macrophages following Fcγ receptor ligation
-
Cappiello, M. G., Sutterwala, F. S., Trinchieri, G., Mosser, D. M. & Ma, X. Suppression of IL-12 transcription in macrophages following Fcγ receptor ligation. J. Immunol. 166, 4498-4506 (2001).
-
(2001)
J. Immunol
, vol.166
, pp. 4498-4506
-
-
Cappiello, M.G.1
Sutterwala, F.S.2
Trinchieri, G.3
Mosser, D.M.4
Ma, X.5
-
66
-
-
33644538566
-
Ligation of the FcRγ chain-associated human osteoclast-associated receptor enhances the proinflammatory responses of human monocytes and neutrophils
-
Merck, E. et al. Ligation of the FcRγ chain-associated human osteoclast-associated receptor enhances the proinflammatory responses of human monocytes and neutrophils. J. Immunol. 176, 3149-3156 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 3149-3156
-
-
Merck, E.1
-
67
-
-
1542514777
-
Myeloid differentiation factor 88 is required for cross-priming in vivo
-
Palliser, D., Ploegh, H. & Boes, M. Myeloid differentiation factor 88 is required for cross-priming in vivo. J. Immunol. 172, 3415-3421 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 3415-3421
-
-
Palliser, D.1
Ploegh, H.2
Boes, M.3
-
68
-
-
33645101274
-
MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
-
Sun, D. & Ding, A. MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA. Nature Immunol. 7, 375-381 (2006).
-
(2006)
Nature Immunol
, vol.7
, pp. 375-381
-
-
Sun, D.1
Ding, A.2
-
69
-
-
0036784614
-
Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis
-
Reiling, N. et al. Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis. J. Immunol. 169, 3480-3484 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 3480-3484
-
-
Reiling, N.1
-
70
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang, T. et al. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nature Med. 10, 1366-1373 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
-
71
-
-
0842342607
-
-
Kurt-Jones, E. A. et al. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc. Natl Acad. Sci. USA 101, 1315-1320 (2004). References 70 and 71 describe the detrimental effects of specific TLR signals in viral infection.
-
Kurt-Jones, E. A. et al. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc. Natl Acad. Sci. USA 101, 1315-1320 (2004). References 70 and 71 describe the detrimental effects of specific TLR signals in viral infection.
-
-
-
-
72
-
-
32444432610
-
-
Sutmuller, R. P. et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J. Clin. Invest. 116, 485-494 (2006). This study describes how TLR signalling can negatively regulate immune responses through the induction of regulatory T cells.
-
Sutmuller, R. P. et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J. Clin. Invest. 116, 485-494 (2006). This study describes how TLR signalling can negatively regulate immune responses through the induction of regulatory T cells.
-
-
-
-
73
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta, K. et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc. Natl Acad. Sci. USA 101, 3516-3521 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
-
74
-
-
33646200348
-
Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo
-
Szomolanyi-Tsuda, E., Liang, X., Welsh, R. M., Kurt-Jones, E. A. & Finberg, R. W. Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo. J. Virol. 80, 4286-4291 (2006).
-
(2006)
J. Virol
, vol.80
, pp. 4286-4291
-
-
Szomolanyi-Tsuda, E.1
Liang, X.2
Welsh, R.M.3
Kurt-Jones, E.A.4
Finberg, R.W.5
-
75
-
-
27744451943
-
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-α release and initiation of immune responses in vivo
-
Delale, T. et al. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-α release and initiation of immune responses in vivo. J. Immunol. 175, 6723-6732 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 6723-6732
-
-
Delale, T.1
-
76
-
-
0018841829
-
Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene
-
O'Brien, A. D. et al. Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene. J. Immunol. 124, 20-24 (1980).
-
(1980)
J. Immunol
, vol.124
, pp. 20-24
-
-
O'Brien, A.D.1
-
77
-
-
0036451206
-
TLR4 as the mammalian endotoxin sensor
-
Beutler, B. TLR4 as the mammalian endotoxin sensor. Curr. Top. Microbiol. Immunol. 270, 109-120 (2002).
-
(2002)
Curr. Top. Microbiol. Immunol
, vol.270
, pp. 109-120
-
-
Beutler, B.1
-
78
-
-
1642317049
-
-
Weiss, D. S., Raupach, B., Takeda, K., Akira, S. & Zychlinsky, A. Toll-like receptors are temporally involved in host defense. J. Immunol. 172, 4463-4469 (2004). An early paper describing TLR cooperation in the control of bacterial infection.
-
Weiss, D. S., Raupach, B., Takeda, K., Akira, S. & Zychlinsky, A. Toll-like receptors are temporally involved in host defense. J. Immunol. 172, 4463-4469 (2004). An early paper describing TLR cooperation in the control of bacterial infection.
-
-
-
-
79
-
-
33750833949
-
-
Koga, R. et al. TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi. J. Immunol. 177, 7059-7066 (2006). The first report of cooperation of TRIF- and MyD88-dependent signalling pathways in host defence in vivo.
-
Koga, R. et al. TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi. J. Immunol. 177, 7059-7066 (2006). The first report of cooperation of TRIF- and MyD88-dependent signalling pathways in host defence in vivo.
-
-
-
-
80
-
-
1142298755
-
p47 GTPases: Regulators of immunity to intracellular pathogens
-
Taylor, G. A., Feng, C. G. & Sher, A. p47 GTPases: regulators of immunity to intracellular pathogens. Nature Rev. Immunol. 4, 100-109 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 100-109
-
-
Taylor, G.A.1
Feng, C.G.2
Sher, A.3
-
81
-
-
6344241296
-
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi
-
Oliveira, A. C. et al. Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi. J. Immunol. 173, 5688-5696 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 5688-5696
-
-
Oliveira, A.C.1
-
82
-
-
33745174546
-
-
Turvey, S. E. & Hawn, T. R. Towards subtlety: understanding the role of Toll-like receptor signaling in susceptibility to human infections. Clin. Immunol. 120, 1-9 (2006). A recent review of the effect of human TLR polymorphisms on host resistance to infectious diseases.
-
Turvey, S. E. & Hawn, T. R. Towards subtlety: understanding the role of Toll-like receptor signaling in susceptibility to human infections. Clin. Immunol. 120, 1-9 (2006). A recent review of the effect of human TLR polymorphisms on host resistance to infectious diseases.
-
-
-
-
83
-
-
19944431742
-
Inherited disorders of human Toll-like receptor signaling: Immunological implications
-
Ku, C. L. et al. Inherited disorders of human Toll-like receptor signaling: immunological implications. Immunol. Rev. 203, 10-20 (2005).
-
(2005)
Immunol. Rev
, vol.203
, pp. 10-20
-
-
Ku, C.L.1
-
84
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
Krieg, A. M. Therapeutic potential of Toll-like receptor 9 activation. Nature Rev. Drug Discov. 5, 471-484 (2006).
-
(2006)
Nature Rev. Drug Discov
, vol.5
, pp. 471-484
-
-
Krieg, A.M.1
-
85
-
-
27244443079
-
-
+ T cell responses in nonhuman primates. Proc. Natl Acad. Sci. USA 102, 15190-15194 (2005). This study describes the effects of coupling a TLR ligand to antigen on the immune response induced to a vaccine antigen in a primate model.
-
+ T cell responses in nonhuman primates. Proc. Natl Acad. Sci. USA 102, 15190-15194 (2005). This study describes the effects of coupling a TLR ligand to antigen on the immune response induced to a vaccine antigen in a primate model.
-
-
-
-
87
-
-
33745945647
-
Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
-
Warger, T. et al. Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo. Blood 108, 544-550 (2006).
-
(2006)
Blood
, vol.108
, pp. 544-550
-
-
Warger, T.1
-
88
-
-
32944455665
-
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity
-
Querec, T. et al. Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J. Exp. Med. 203, 413-424 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 413-424
-
-
Querec, T.1
-
89
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato, S. et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol. 171, 4304-4310 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
-
90
-
-
0036178266
-
Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback
-
Levy, D. E., Marie, I., Smith, E. & Prakash, A. Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback. J. Interferon Cytokine Res. 22, 87-93 (2002).
-
(2002)
J. Interferon Cytokine Res
, vol.22
, pp. 87-93
-
-
Levy, D.E.1
Marie, I.2
Smith, E.3
Prakash, A.4
-
91
-
-
32644464262
-
IRF family proteins and type I interferon induction in dendritic cells
-
Tailor, P., Tamura, T. & Ozato, K. IRF family proteins and type I interferon induction in dendritic cells. Cell Res. 16, 134-140 (2006).
-
(2006)
Cell Res
, vol.16
, pp. 134-140
-
-
Tailor, P.1
Tamura, T.2
Ozato, K.3
-
92
-
-
7444250116
-
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
-
Honda, K. et al. Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. Proc. Natl Acad. Sci. USA 101, 15416-15421 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 15416-15421
-
-
Honda, K.1
-
93
-
-
5444274514
-
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai, T. et al. Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nature Immunol. 5, 1061-1068 (2004).
-
(2004)
Nature Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
-
94
-
-
0035968246
-
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon-α genes
-
Barnes, B. J., Moore, P. A. & Pitha, P. M. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon-α genes. J. Biol. Chem. 276, 23382-23390 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 23382-23390
-
-
Barnes, B.J.1
Moore, P.A.2
Pitha, P.M.3
-
95
-
-
33746884630
-
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
-
Guiducci, C. et al. Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J. Exp. Med. 203, 1999-2008 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1999-2008
-
-
Guiducci, C.1
-
96
-
-
33745207594
-
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors
-
Netea, M. G. et al. Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J. Clin. Invest. 116, 1642-1650 (2006).
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1642-1650
-
-
Netea, M.G.1
-
97
-
-
15944390196
-
How C-type lectins detect pathogens
-
Cambi, A., Koopman, M. & Figdor, C. G. How C-type lectins detect pathogens. Cell. Microbiol. 7, 481-488 (2005).
-
(2005)
Cell. Microbiol
, vol.7
, pp. 481-488
-
-
Cambi, A.1
Koopman, M.2
Figdor, C.G.3
-
98
-
-
30444461383
-
Fcγ receptors: Old friends and new family members
-
Nimmerjahn, F. & Ravetch, J. V. Fcγ receptors: old friends and new family members. Immunity 24, 19-28 (2006).
-
(2006)
Immunity
, vol.24
, pp. 19-28
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
99
-
-
0035953547
-
TREM-1 amplifies inflammation and is a crucial mediator of septic shock
-
Bouchon, A., Facchetti, F., Weigand, M. A. & Colonna, M. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410, 1103-1107 (2001).
-
(2001)
Nature
, vol.410
, pp. 1103-1107
-
-
Bouchon, A.1
Facchetti, F.2
Weigand, M.A.3
Colonna, M.4
-
100
-
-
0028987562
-
Interleukin-12 is required for interferon-? production and lethality in lipopolysaccharide-induced shock in mice
-
Wysocka, M. et al. Interleukin-12 is required for interferon-? production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25, 672-676 (1995).
-
(1995)
Eur. J. Immunol
, vol.25
, pp. 672-676
-
-
Wysocka, M.1
-
101
-
-
0035202483
-
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
-
Asselin-Paturel, C. et al. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nature Immunol. 2, 1144-1150 (2001).
-
(2001)
Nature Immunol
, vol.2
, pp. 1144-1150
-
-
Asselin-Paturel, C.1
-
102
-
-
0034944385
-
Type I interferons and IL-12: Convergence and cross-regulation among mediators of cellular immunity
-
Byrnes, A. A. et al. Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity. Eur. J. Immunol. 31, 2026-2034 (2001).
-
(2001)
Eur. J. Immunol
, vol.31
, pp. 2026-2034
-
-
Byrnes, A.A.1
-
103
-
-
0037017381
-
Reciprocal activating interaction between natural killer cells and dendritic cells
-
Gerosa, F. et al. Reciprocal activating interaction between natural killer cells and dendritic cells. J. Exp. Med. 195, 327-333 (2002).
-
(2002)
J. Exp. Med
, vol.195
, pp. 327-333
-
-
Gerosa, F.1
-
104
-
-
11844268647
-
The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions
-
Gerosa, F. et al. The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions. J. Immunol. 174, 727-734 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 727-734
-
-
Gerosa, F.1
-
105
-
-
0028911482
-
Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor α production
-
D'Andrea, A., Ma, X., Aste-Amezaga, M., Paganin, C. & Trinchieri, G. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor α production. J. Exp. Med. 181, 537-546 (1995).
-
(1995)
J. Exp. Med
, vol.181
, pp. 537-546
-
-
D'Andrea, A.1
Ma, X.2
Aste-Amezaga, M.3
Paganin, C.4
Trinchieri, G.5
|