Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors

Journal of Leukocyte Biology

Volumn 80, Issue 6, 2006, Pages 1454-1461

  Netea, Mihai G ^a,b   Azam, Tania ^a   Ferwerda, Gerben ^b   Girardin, Stephen E ^c   Kim, Soo Hyun ^a,d   Dinarello, Charles A ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSTITUT PASTEUR   (France)

^d Konkuk University   (South Korea)

Author keywords

Caspase 1; Cytokines; NOD2

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CELL RECEPTOR; GLYCOPROTEIN; INHIBITOR PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; NEURONAL APOPTOSIS INHIBITORY PROTEIN; PEPTIDOGLYCAN; PROTEIN ANTIBODY; PROTEIN CIITA; PROTEIN HET E; PROTEIN MUROPEPTIDE; PROTEIN TP 1 LEUCINE RICH REPEAT; PROTEIN TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; PROTEIN TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 ANTIBODY; RECEPTOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLAMMATION; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CASPASE 1; CELL DEGRANULATION; CELL LINE; CELLS, CULTURED; CYTOKINES; HUMANS; INFLAMMATION; MEMBRANE GLYCOPROTEINS; NEUTROPHILS; NOD2 SIGNALING ADAPTOR PROTEIN; PEPTIDOGLYCAN; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PATTERN RECOGNITION; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS);

EID: 33845456631     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1205758     Document Type: Article

References (41)

1. Medzhitov, R. (2001) Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145.
2. Akira, S., Hemmi, H. (2003) Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85, 85-95.
3. Kufer, T. A., Fritz, J. H., Philpott, D. J. (2005) NACHT-LRR proteins (NLRs) in bacterial infection and immunity. Trends Microbiol. 13, 381-388.
4. Gantner, B. N., Simmons, R. M., Canavera, S. J., Akira, S., Underhill, D. M. (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197, 1107-1117.
5. Brown, G. D., Herre, J., Williams, D. L., Willment, J. A., Marshall, A. S., Gordon, S. (2003) Dectin-1 mediates the biological effects of β-glucans. J. Exp. Med. 197, 1119-1124.
6. Lotze, M. T., Tracey, K. J. (2005) High mobility group box 1 protein (HMCB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5, 331-337.
7. Colonna, M. (2003) TREMs in the immune system and beyond. Nat. Rev. Immunol. 3, 445-453.
8. Kelker, M. S., Foss, T. R., Peti, W., Kelly, J. W., Wuthrich, K., Wilson, I. A. (2004) Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47A. J. Mol. Biol. 342, 1237-1248.
9. Bouchon, A., Dietrich, J., Colonna, M. (2000) Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J. Immunol. 164, 4991-4995.
10. Radsak, M. P., Salih, H. R., Rammensee, H-G., Schild, H. (2004) Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: differential regulation of activation and survival. J. Immunol. 172, 4956-4963.
11. Bleharski, J. R., Kiessler, V., Buonsanti, C., Sieling, P. A., Stenger, S., Colonna, M., Modlin, R. L. (2003) A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J. Immunol. 170, 3812-3818.
12. Bouchon, A., Facchetti, F., Weigand, M. A., Colonna, M. (2001) TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410, 1103-1107.
13. Inohara, N., Chamaillard, M., McDonald, C., Nunez, G. (2005) NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74, 355-383.
14. Girardin, S. E., Boneca, I. G., Viala, J., Chamaillard, M., Labigne, A., Thomas, G., Philpott, D. J., Sansonetti, P. J. (2003) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278, 8869-8872.
15. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S., Hashimoto, M., Foster, S. J., Moran, A. P., Fernandez-Luna, J. L., Nunez, G. (2003) Host recognition of bacterial muramyl dipeptide mediated through Nod2. Implications for Crohn's disease. J. Biol. Chem. 278, 5509-5512.
16. Martinon, F., Agostini, L., Meylan, E., Tschopp, J. (2004) Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14, 1929-1934.
17. Girardin, S. E., Boneca, I. G., Carneiro, L. A. M., Antignac, A., Jehanno, M., Viala, J., Tedin, K., Taha, M-K., Labigne, A., Zahringer, U., Coyle, A. J., DiStefano, P. S., Bertin, J., Sansonetti, P. J., Philpott, D. J. (2003) Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan. Science 300, 1584-1587.
18. Kim, S-H., Eisenstein, M., Reznikov, L., Fantuzzi, G., Novick, D., Rubinstein, M., Dinarello, C. A. (2000) Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc. Natl. Acad. Sci. USA 97, 1190-1195.
19. Puren, A. J., Razeghi, P., Fantuzzi, G., Dinarello, C. A. (1998) Interleukin-18 enhances lipopolysaccharide-induced interferon-γ production in human whole blood cultures. J. Infect. Dis. 178, 1830-1834.
20. Chomczynski, P., Sacchi, N. (1987) Single step method of RNA isolation by acid guanidinum phenol chloroform extraction. Anal. Biochem. 162, 156-159.
21. Martinon, F., Tschopp, J. (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117, 561-574.
22. Gibot, S., Kolopp-Sarda, M.N., Bene, M.C., Bollaert, P.E., A., L., Mory, F., Levy, B., Faure, G.C. (2004) A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med. 200, 1419-1426.
23. Knapp, S., Gibot, S., de Vos, A., Versteeg, H. H., Colonna, M., van der Poll, T. (2004) Expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia. J. Immunol. 173, 7131-7134.
24. Gibot, S., Cravoisy, A., Levy, B., Bene, M. C., Faure, G., Bollaert, P. E. (2004) Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia. N. Engl. J. Med. 350, 451-458.
25. Gibot, S., Kolopp-Sarda, M. N., Bene, M. C., Cravoisy, A., Levy, B., Faure, G. C., Bollaert, P. E. (2004) Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann. Intern. Med. 141, 9-15.
26. Gibot, S., Cravoisy, A. (2004) Soluble form of the triggering receptor expressed on myeloid cells-1 as a marker of microbial infection. Clin. Med. res. 2, 181-187.
27. Netea, M. G., Kullberg, B. J., de Jong, D., Francke, B., Sprong, T., Naber, T., Drenth, J. P. H., Van der Meer, J. W. M. (2004) NOD2 mediates induction of the antiinflammatory signals induced by TLR2-ligands: implications for Crohn's disease. Eur. J. Immunol. 34, 2052-2059.
28. Netea, M. G., Ferwerda, G., De Jong, D. J., Jansen, T., Jacobs, L., Kramer, M., Naber, T. H. J., Drenth, J. P. H., Girardin, S. E., Kullberg, B. J., Adema, G. J., Van der Meer, J. W. (2005) NOD2 modulates specific Toll-like receptor pathways for the induction of cytokine release. J. Immunol. 174, 6518-6523.
29. Watanabe, T., Kitani, A., Murray, P. J., Strober, W. (2004) NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat. Immunol. 5, 800-808.
30. van Heel, D. A., Ghosh, S., Hunt, K., Lundberg, A. M., Ahmad, T., McGovern, D. P., Onnie, C., Negoro, K., Goldthorpe, S., Foxwell, B. M., Mathew, C. G., Forbes, A., Jewell, D. P., Playford, R. J. (2005) Muramyl dipeptide and Toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet 365, 1794-1796.
31. Hisamatsu, T., Suzuki, M., Reinecker, H-C., Nadeau, W. J., McCormick, B. A., Podolsky, D. K. (2003) CARD15/Nod2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 124, 993-1000.
32. Kobayashi, K. S., Chamaillard, M., Ogura, Y., Henegariu, O., Inohara, N., Nunez, G., Flavell, R. A. (2005) NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307, 731-734.
33. Lucas, M., Daniel, L., Tomasello, E., Guia, S., Horschowski, N., Aoki, N., Figarella-Branger, D., Gomez, S., Vivier, E. (2002) Massive inflammatory syndrome and lymphocytic immunodeficiency in KARAP/DAP12-transgenic mice. Eur. J. Immunol. 32, 2653-2663.
34. Schenk, M., Bouchon, A., Birrer, S., Colonna, M., Mueller, C. (2005) Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine. J. Immunol. 174, 517-524.
35. Hugot, J-P., Chamaillard, M., Zouali, H., Lesage, S., Cezard, J-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411, 599-603.
36. Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karalluskas, R., Duerr, R. H., et al. (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606.
37. Yoo, N. J., Park, W. S., Kim, S. Y., Reed, J. C., Son, S. G., Lee, J. Y., Lee, S. H. (2002) Nod1, a CARD protein, enhances pro-interleukin-1β processing through the interaction with pro-caspase-1. Biochem. Biophys. Res. Commun. 299, 652-658.
38. Kobayashi, K., al., e. (2002) RICK/Rip2/CARDIAK mediates signaling for receptors of the innate and adaptive immune systems. Nature 416, 194-199.
39. Hamerman, J. A., Tchao, N. K., Lowell, C. A., Lanier, L. L. (2005) Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12. Nat. Immunol. 6, 579-586.
40. Turnbull, I. R., McDunn, J. E., Takai, T., Townsend, R. R., Cobb, J. P., Colonna, M. (2005) DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis. J. Exp. Med. 202, 363-369.
41. Daws, M. R., Sullam, P. M., Niemi, E. C., Chen, T. T., Tchao, N. K., Seaman, W. E. (2003) Pattern recognition by TREM-2: binding of anionic ligands. J. Immunol. 171, 594-599.