-
1
-
-
0037347050
-
Toll receptors and pathogen resistance
-
Takeda, K., and S. Akira. 2003. Toll receptors and pathogen resistance. Cell Microbiol. 5:143.
-
(2003)
Cell Microbiol.
, vol.5
, pp. 143
-
-
Takeda, K.1
Akira, S.2
-
2
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov, R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1:135.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 135
-
-
Medzhitov, R.1
-
3
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe, K., X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, et al. 2003. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424:743.
-
(2003)
Nature
, vol.424
, pp. 743
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
-
4
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald, K. A., E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413:78.
-
(2001)
Nature
, vol.413
, pp. 78
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
-
5
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng, T., G. M. Barton, R. A. Flavell, and R. Medzhitov. 2002. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420:329.
-
(2002)
Nature
, vol.420
, pp. 329
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
6
-
-
0037320451
-
TI-CAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
-
Oshiumi, H., M. Matsumoto, K. Funami, T. Akazawa, and T. Seya. 2003. TI-CAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction. Nat. Immunol. 4:161.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 161
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
7
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
-
Yamamoto, M., S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J. Immunol. 169:6668.
-
(2002)
J. Immunol.
, vol.169
, pp. 6668
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
8
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115.
-
(1999)
Immunity
, vol.11
, pp. 115
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
9
-
-
0036679732
-
Of mice and men: Species variations of Toll-like receptor expression
-
Rehli, M. 2002. Of mice and men: species variations of Toll-like receptor expression. Trends Immunol. 23:375.
-
(2002)
Trends Immunol.
, vol.23
, pp. 375
-
-
Rehli, M.1
-
10
-
-
1642401857
-
-
World Health Organization, Geneva
-
WHO. 1998. Typhoid fever. World Health Organization, Geneva.
-
(1998)
Typhoid Fever
-
-
-
11
-
-
0035123755
-
Salmonella: A model for bacterial pathogenesis
-
Ohl, M. E., and S. I. Miller. 2001. Salmonella: a model for bacterial pathogenesis. Annu. Rev. Med. 52:259.
-
(2001)
Annu. Rev. Med.
, vol.52
, pp. 259
-
-
Ohl, M.E.1
Miller, S.I.2
-
12
-
-
0019407618
-
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
-
Hoiseth, S. K., and B. A. Stocker. 1981. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 291:238.
-
(1981)
Nature
, vol.291
, pp. 238
-
-
Hoiseth, S.K.1
Stocker, B.A.2
-
13
-
-
0029117137
-
Simultaneous identification of bacterial virulence genes by negative selection
-
Hensel, M., J. E. Shea, C. Gleeson, M. D. Jones, E. Dalton, and D. W. Holden. 1995. Simultaneous identification of bacterial virulence genes by negative selection. Science 269:400.
-
(1995)
Science
, vol.269
, pp. 400
-
-
Hensel, M.1
Shea, J.E.2
Gleeson, C.3
Jones, M.D.4
Dalton, E.5
Holden, D.W.6
-
14
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:3749.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
15
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11:443.
-
(1999)
Immunity
, vol.11
, pp. 443
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
16
-
-
23044530313
-
Studying trafficking of intracellular pathogens in antigen-presenting cells
-
P. Sansonetti, and A. Zychlinsky, eds. Academic Press, New York
-
Schaible, U., and S. Kaufmann. 2002. Studying trafficking of intracellular pathogens in antigen-presenting cells. In Molecular Cellular Microbiology, Vol. 31. P. Sansonetti, and A. Zychlinsky, eds. Academic Press, New York, p. 343.
-
(2002)
Molecular Cellular Microbiology
, vol.31
, pp. 343
-
-
Schaible, U.1
Kaufmann, S.2
-
17
-
-
0035188434
-
Salmonella interactions with host cells: Type III secretion at work
-
Galan, J. E. 2001. Salmonella interactions with host cells: type III secretion at work. Annu. Rev. Cell Dev. Biol. 17:53.
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 53
-
-
Galan, J.E.1
-
18
-
-
0035164253
-
Regulation of Toll-like receptors in human monocytes and dendritic cells
-
Visintin, A., A. Mazzoni, J. H. Spitzer, D. H. Wyllie, S. K. Dower, and D. M. Segal. 2001. Regulation of Toll-like receptors in human monocytes and dendritic cells. J. Immunol. 166:249.
-
(2001)
J. Immunol.
, vol.166
, pp. 249
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.H.3
Wyllie, D.H.4
Dower, S.K.5
Segal, D.M.6
-
19
-
-
0034177888
-
Cutting edge: Cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages
-
Akashi, S., R. Shimazu, H. Ogata, Y. Nagai, K. Takeda, M. Kimoto, and K. Miyake. 2000. Cutting edge: cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J. Immunol. 164:3471.
-
(2000)
J. Immunol.
, vol.164
, pp. 3471
-
-
Akashi, S.1
Shimazu, R.2
Ogata, H.3
Nagai, Y.4
Takeda, K.5
Kimoto, M.6
Miyake, K.7
-
20
-
-
20244384395
-
Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression
-
Nomura, F., S. Akashi, Y. Sakao, S. Sato, T. Kawai, M. Matsumoto, K. Nakanishi, M. Kimoto, K. Miyake, K. Takeda, and S. Akira. 2000. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J. Immunol. 164:3476.
-
(2000)
J. Immunol.
, vol.164
, pp. 3476
-
-
Nomura, F.1
Akashi, S.2
Sakao, Y.3
Sato, S.4
Kawai, T.5
Matsumoto, M.6
Nakanishi, K.7
Kimoto, M.8
Miyake, K.9
Takeda, K.10
Akira, S.11
-
21
-
-
0025952479
-
The involvement of tumor necrosis factor in immunity to Salmonella infection
-
Tite, J. P., G. Dougan, and S. N. Chatfield. 1991. The involvement of tumor necrosis factor in immunity to Salmonella infection. J. Immunol. 147:3161.
-
(1991)
J. Immunol.
, vol.147
, pp. 3161
-
-
Tite, J.P.1
Dougan, G.2
Chatfield, S.N.3
-
22
-
-
0035956904
-
Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages
-
Vazquez-Torres, A., G. Fantuzzi, C. K. Edwards, 3rd, C. A. Dinarello, and F. C. Fang. 2001. Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages. Proc. Natl. Acad. Sci. USA 98:2561.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2561
-
-
Vazquez-Torres, A.1
Fantuzzi, G.2
Edwards III, C.K.3
Dinarello, C.A.4
Fang, F.C.5
-
23
-
-
0037152173
-
Yersinia V-antigen exploits Toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
-
Sing, A., D. Rost, N. Tvardovskaia, A. Roggenkamp, A. Wiedemann, C. J. Kirschning, M. Aepfelbacher, and J. Heesemann. 2002. Yersinia V-antigen exploits Toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J. Exp. Med. 196:1017.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1017
-
-
Sing, A.1
Rost, D.2
Tvardovskaia, N.3
Roggenkamp, A.4
Wiedemann, A.5
Kirschning, C.J.6
Aepfelbacher, M.7
Heesemann, J.8
-
24
-
-
0034139626
-
Susceptibility to Leishmania major infection in mice: Multiple loci and heterogeneity of immunopathological phenotypes
-
Lipoldova, M., M. Svobodova, M. Krulova, H. Havelkova, J. Badalova, E. Nohynkova, V. Holan, A. A. Hart, P. Volf, and P. Demant. 2000. Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes. Genes Immun. 1:200.
-
(2000)
Genes Immun.
, vol.1
, pp. 200
-
-
Lipoldova, M.1
Svobodova, M.2
Krulova, M.3
Havelkova, H.4
Badalova, J.5
Nohynkova, E.6
Holan, V.7
Hart, A.A.8
Volf, P.9
Demant, P.10
-
25
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. V. Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085.
-
(1998)
Science
, vol.282
, pp. 2085
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
26
-
-
0033563143
-
Cutting edge: Functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: In vivo evidence for a dominant negative mutation
-
Vogel, S. N., D. Johnson, P. Y. Perera, A. Medvedev, L. Lariviere, S. T. Qureshi, and D. Malo. 1999. Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation. J. Immunol. 162:5666.
-
(1999)
J. Immunol.
, vol.162
, pp. 5666
-
-
Vogel, S.N.1
Johnson, D.2
Perera, P.Y.3
Medvedev, A.4
Lariviere, L.5
Qureshi, S.T.6
Malo, D.7
-
27
-
-
0035421993
-
Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions
-
Forbes, J. R., and P. Gros. 2001. Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends Microbiol. 9:397.
-
(2001)
Trends Microbiol.
, vol.9
, pp. 397
-
-
Forbes, J.R.1
Gros, P.2
-
28
-
-
0042405132
-
Recognition of microbial infection by Toll-like receptors
-
Kopp, E., and R. Medzhitov. 2003. Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 15:396.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 396
-
-
Kopp, E.1
Medzhitov, R.2
-
29
-
-
0018841829
-
Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene
-
O'Brien, A. D., D. L. Rosenstreich, I. Scher, G. H. Campbell, R. P. MacDermott, and S. B. Formal. 1980. Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene. J. Immunol. 124:20.
-
(1980)
J. Immunol.
, vol.124
, pp. 20
-
-
O'Brien, A.D.1
Rosenstreich, D.L.2
Scher, I.3
Campbell, G.H.4
MacDermott, R.P.5
Formal, S.B.6
-
30
-
-
0036838764
-
Respiratory syncytial virus-induced activation of nuclear factor-κB in the lung involves alveolar macrophages and Toll-like receptor 4-dependent pathways
-
Haeberle, H. A., R. Takizawa, A. Casola, A. R. Brasier, H. J. Dieterich, N. Van Rooijen, Z. Gatalica, and R. P. Garofalo. 2002. Respiratory syncytial virus-induced activation of nuclear factor-κB in the lung involves alveolar macrophages and Toll-like receptor 4-dependent pathways. J. Infect. Dis. 186:1199.
-
(2002)
J. Infect. Dis.
, vol.186
, pp. 1199
-
-
Haeberle, H.A.1
Takizawa, R.2
Casola, A.3
Brasier, A.R.4
Dieterich, H.J.5
Van Rooijen, N.6
Gatalica, Z.7
Garofalo, R.P.8
-
31
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones, E. A., L. Popova, L. Kwinn, L. M. Haynes, L. P. Jones, R. A. Tripp, E. E. Walsh, M. W. Freeman, D. T. Golenbock, L. J. Anderson, and R. W. Finberg. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1:398.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
32
-
-
0034768425
-
Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus
-
Haynes, L. M., D. D. Moore, E. A. Kurt-Jones, R. W. Finberg, L. J. Anderson, and R. A. Tripp. 2001. Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus. J. Virol. 75:10730.
-
(2001)
J. Virol.
, vol.75
, pp. 10730
-
-
Haynes, L.M.1
Moore, D.D.2
Kurt-Jones, E.A.3
Finberg, R.W.4
Anderson, L.J.5
Tripp, R.A.6
-
33
-
-
0037502208
-
Subversion of the innate immune system by a retrovirus
-
Jude, B. A., Y. Pobezinskaya, J. Bishop, S. Parke, R. M. Medzhitov, A. V. Chervonsky, and T. V. Golovkina. 2003. Subversion of the innate immune system by a retrovirus. Nat. Immunol. 4:573.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 573
-
-
Jude, B.A.1
Pobezinskaya, Y.2
Bishop, J.3
Parke, S.4
Medzhitov, R.M.5
Chervonsky, A.V.6
Golovkina, T.V.7
-
34
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with Toll-like receptor 4
-
Rassa, J. C., J. L. Meyers, Y. Zhang, R. Kudaravalli, and S. R. Ross. 2002. Murine retroviruses activate B cells via interaction with Toll-like receptor 4. Proc. Natl. Acad. Sci. USA 99:2281.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2281
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
35
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle, S., S. Vaidya, R. O'Connell, H. Dadgostar, P. Dempsey, T. Wu, G. Rao, R. Sun, M. Haberland, R. Modlin, and G. Cheng. 2002. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17:251.
-
(2002)
Immunity
, vol.17
, pp. 251
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
Cheng, G.11
-
36
-
-
0030722084
-
Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors
-
Ruby, J., H. Bluethmann, and J. J. Peschon. 1997. Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors. J. Exp. Med. 186:1591.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1591
-
-
Ruby, J.1
Bluethmann, H.2
Peschon, J.J.3
-
37
-
-
0034044735
-
The function of type I interferons in antimicrobial immunity
-
Bogdan, C. 2000. The function of type I interferons in antimicrobial immunity. Curr. Opin. Immunol. 12:419.
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 419
-
-
Bogdan, C.1
-
38
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413:732.
-
(2001)
Nature
, vol.413
, pp. 732
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
|