HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 42, 2005, Pages 15190-15194

  Wille Reece, Ulrike ^a   Flynn, Barbara J ^a   Loré, Karin ^a   Koup, Richard A ^a   Kedl, Ross M ^b,d   Mattapallil, Joseph J ^a   Weiss, Walter R ^c   Roederer, Mario ^a   Seder, Robert A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b 3M COMPANY   (United States)

^c NAVAL MEDICAL RESEARCH CENTER   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Cellular immunity; Cross presentation; Dendritic cell; Vaccine

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAG PROTEIN; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; INTERLEUKIN 2; OLIGODEOXYNUCLEOTIDE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ARTICLE; CELLULAR IMMUNITY; CPG ISLAND; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNIZATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; VIRUS INFECTION;

AIDS VACCINES; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; GENE PRODUCTS, GAG; HIV ANTIGENS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; LIGANDS; NUCLEOCAPSID PROTEINS; OLIGODEOXYRIBONUCLEOTIDES; PRIMATES; T-LYMPHOCYTE SUBSETS; TH1 CELLS;

ALPHAVIRUS; ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; PRIMATES;

EID: 27244443079     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507484102     Document Type: Article

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