A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1α

Journal of Cell Science

Volumn 119, Issue 16, 2006, Pages 3467-3480

  Qutub, Amina A ^a   Popel, Aleksander S ^a  

^a Johns Hopkins University   (United States)

Author keywords

Computational modeling; Hypoxic response; Mathematical modeling; Oxygen sensing

Indexed keywords

2 OXOGLUTARIC ACID; ASCORBIC ACID; FERROUS ION; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CANCER; CELL ACTIVATION; CONTROLLED STUDY; EXERCISE; GENE EXPRESSION; GENETIC CODE; HYDROXYLATION; HYPOXIA; IRON THERAPY; ISCHEMIA; MATHEMATICAL MODEL; OXYGEN CONCENTRATION; OXYGEN SENSING; PREDICTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; VITAMIN SUPPLEMENTATION;

ASCORBIC ACID; CELL HYPOXIA; COMPUTER SIMULATION; DIETARY SUPPLEMENTS; HUMANS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IRON; MODELS, BIOLOGICAL; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 33748774664     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.03087     Document Type: Article

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