Determination and comparison of specific activity of the HIF-prolyl hydroxylases

FEBS Letters

Volumn 576, Issue 1-2, 2004, Pages 145-150

  Tuckerman, Jason R ^a   Zhao, Yuguang ^a   Hewitson, Kirsty S ^b   Tian, Ya Min ^a   Pugh, Christopher W ^a   Ratcliffe, Peter J ^a   Mole, David R ^a  

^a OX3 7BN ^*  (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

HIF, hypoxia inducible factor; Hypoxia inducible factor ; PHD, prolyl hydroxylase domain containing protein; Prolyl hydroxylase domain containing protein; pVHL, von Hippel Lindau tumor suppressor protein; von Hippel Lindau protein

Indexed keywords

CELL EXTRACT; HYPOXIA INDUCIBLE FACTOR; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 1; PROLYL HYDROXYLASE 2; PROLYL HYDROXYLASE 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACULOVIRUS; BREAST CANCER; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL ASSAY; CELL HYPOXIA; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; INSECT CELL; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; CATALYSIS; CELL EXTRACTS; CELL HYPOXIA; CELL LINE; HUMANS; HYDROXYLATION; HYDROXYPROLINE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOENZYMES; KINETICS; OXYGEN; PEPTIDES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SENSITIVITY AND SPECIFICITY; SPODOPTERA; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 4944223879     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.09.005     Document Type: Article

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