-
1
-
-
0036320934
-
2- regulated gene expression
-
2- regulated gene expression. FASEB J 2002; 16:1151-62.
-
(2002)
FASEB J
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
2
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002; 8:S62-7.
-
(2002)
Trends Mol Med
, vol.8
-
-
Semenza, G.L.1
-
3
-
-
0037326037
-
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
-
Pugh CW, Ratcliffe PJ. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin Cancer Biol 2003; 13:83-9.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 83-89
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
4
-
-
0037490210
-
Hypoxia-inducible factor and its biomedical relevance
-
Huang LE, Bunn HF. Hypoxia-inducible factor and its biomedical relevance. J Biol Chem 2003; 278:19575-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 19575-19578
-
-
Huang, L.E.1
Bunn, H.F.2
-
6
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem 1996; 271:32253-9.
-
(1996)
J Biol Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
8
-
-
0033525830
-
Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway
-
Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. J Biol Chem 1999; 274:6519-25.
-
(1999)
J Biol Chem
, vol.274
, pp. 6519-6525
-
-
Kallio, P.J.1
Wilson, W.J.2
O'Brien, S.3
Makino, Y.4
Poellinger, L.5
-
9
-
-
0030937718
-
Activation of hypoxia-inducible factor-1; definition of regulatoty domains within the alpha subunit
-
Pugh CW, O'Rourke JF, Nagao M, Gleadle JM, Ratcliffe PJ. Activation of hypoxia-inducible factor-1; definition of regulatoty domains within the alpha subunit. J Biol Chem 1997; 272:11205-14.
-
(1997)
J Biol Chem
, vol.272
, pp. 11205-11214
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
10
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995; 270:1230-7.
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
11
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, et al. An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci USA 1996; 93:12969-73.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
Bhattacharya, S.4
Jiang, C.5
Goldberg, M.A.6
-
12
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1α
-
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, et al. Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1α. EMBO J 1998; 17: 6573-86.
-
(1998)
EMBO J
, vol.17
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'Brien, S.3
Carrero, P.4
Makino, Y.5
Tanaka, H.6
-
13
-
-
0032581277
-
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, et al. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998; 394:485-90.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
-
14
-
-
0037214282
-
Hypoxia-inducible factor 1α is essential for cell cycle arrest during hypoxia
-
Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS. Hypoxia-inducible factor 1α is essential for cell cycle arrest during hypoxia. Mol Cell Biol 2003; 23:359-69.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 359-369
-
-
Goda, N.1
Ryan, H.E.2
Khadivi, B.3
McNulty, W.4
Rickert, R.C.5
Johnson, R.S.6
-
15
-
-
0034667433
-
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer
-
Salnikow K, Costa M, Figg WD, Blagosklonny MV. Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. Cancer Res 2000; 60:5630-4.
-
(2000)
Cancer Res
, vol.60
, pp. 5630-5634
-
-
Salnikow, K.1
Costa, M.2
Figg, W.D.3
Blagosklonny, M.V.4
-
16
-
-
3142631736
-
HIF-1α induces cell cycle arrest by functionally counteracting Myc
-
Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, Huang LE. HIF-1α induces cell cycle arrest by functionally counteracting Myc. EMBO J 2004; 23:1949-56.
-
(2004)
EMBO J
, vol.23
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
17
-
-
18644371442
-
Negative regulation of the mammalian UV response by Myc through association with Miz-1
-
Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002; 10:509-21.
-
(2002)
Mol Cell
, vol.10
, pp. 509-521
-
-
Herold, S.1
Wanzel, M.2
Beuger, V.3
Frohme, C.4
Beul, D.5
Hillukkala, T.6
-
18
-
-
0037126303
-
Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002; 419:729-34.
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
19
-
-
0037330625
-
Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
-
Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003; 283:17-21.
-
(2003)
Exp Cell Res
, vol.283
, pp. 17-21
-
-
Gartel, A.L.1
Shchors, K.2
-
20
-
-
0036359548
-
Hypoxia-a key regulatoty factor in tumour growth
-
Harris AL. Hypoxia-a key regulatoty factor in tumour growth. Nat Rev Cancer 2002; 2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
21
-
-
0036680153
-
Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer
-
Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos C, Turley H, Talks K, et al. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. Int J Radiat Oncol Biol Phys 2002; 53:1192-202.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.53
, pp. 1192-1202
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Simopoulos, C.4
Turley, H.5
Talks, K.6
|