Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

Molecular and Cellular Biology

Volumn 22, Issue 15, 2002, Pages 5319-5336

  Groulx, Isabelle ^a   Lee, Stephen ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; NUCLEAR PROTEIN; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; TUMOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; GENETIC TRANSCRIPTION; HALF LIFE TIME; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN DEGRADATION; REOXYGENATION; TUMOR SUPPRESSOR GENE; VON HIPPEL LINDAU DISEASE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BLOTTING, WESTERN; CELL COMPARTMENTATION; CELL HYPOXIA; CELL LINE; CELL NUCLEUS; CYTOPLASM; ENZYME INHIBITORS; FATTY ACIDS, UNSATURATED; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGASES; LUMINESCENT PROTEINS; MICE; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; RECOMBINANT FUSION PROTEINS; RNA POLYMERASE II; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0036314978     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.15.5319-5336.2002     Document Type: Article

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