-
1
-
-
0030024173
-
Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes
-
Acs G., Lee J., Marquez V.E., and Blumberg P.M. Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes. Brain Res. Mol. Brain Res. 35 (1996) 173-182
-
(1996)
Brain Res. Mol. Brain Res.
, vol.35
, pp. 173-182
-
-
Acs, G.1
Lee, J.2
Marquez, V.E.3
Blumberg, P.M.4
-
2
-
-
0034638450
-
Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons
-
Ahluwalia J., Urban L., Capogna M., Bevan S., and Nagy I. Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons. Neuroscience 100 (2000) 685-688
-
(2000)
Neuroscience
, vol.100
, pp. 685-688
-
-
Ahluwalia, J.1
Urban, L.2
Capogna, M.3
Bevan, S.4
Nagy, I.5
-
3
-
-
0035662685
-
The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice
-
Al-Hayani A., Wease K.N., Ross R.A., Pertwee R.G., and Davies S.N. The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. Neuropharmacology 41 (2001) 1000-1005
-
(2001)
Neuropharmacology
, vol.41
, pp. 1000-1005
-
-
Al-Hayani, A.1
Wease, K.N.2
Ross, R.A.3
Pertwee, R.G.4
Davies, S.N.5
-
4
-
-
0026604446
-
Bradykinin modulation of a spinal nociceptive reflex in the rat
-
Bauer M.B., Meller S.T., and Gebhart G.F. Bradykinin modulation of a spinal nociceptive reflex in the rat. Brain Res. 578 (1992) 186-196
-
(1992)
Brain Res.
, vol.578
, pp. 186-196
-
-
Bauer, M.B.1
Meller, S.T.2
Gebhart, G.F.3
-
5
-
-
0025328825
-
Sensory neuron-specific actions of capsaicin: Mechanisms and applications
-
Bevan S., and Szolcsanyi J. Sensory neuron-specific actions of capsaicin: Mechanisms and applications. Trends Pharmacol. Sci. 11 (1990) 330-333
-
(1990)
Trends Pharmacol. Sci.
, vol.11
, pp. 330-333
-
-
Bevan, S.1
Szolcsanyi, J.2
-
7
-
-
0024418739
-
Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture
-
Burgess G.M., Mullaney I., McNeill M., Dunn P.M., and Rang H.P. Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture. J. Neurosci. 9 (1989) 3314-3325
-
(1989)
J. Neurosci.
, vol.9
, pp. 3314-3325
-
-
Burgess, G.M.1
Mullaney, I.2
McNeill, M.3
Dunn, P.M.4
Rang, H.P.5
-
8
-
-
0031033841
-
Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain
-
Cadas H., di Tomaso E., and Piomelli D. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. J. Neurosci. 17 (1997) 1226-1242
-
(1997)
J. Neurosci.
, vol.17
, pp. 1226-1242
-
-
Cadas, H.1
di Tomaso, E.2
Piomelli, D.3
-
9
-
-
0032537734
-
Control of pain initiation by endogenous cannabinoids
-
Calignano A., La Rana G., Giuffrida A., and Piomelli D. Control of pain initiation by endogenous cannabinoids. Nature 394 (1998) 277-281
-
(1998)
Nature
, vol.394
, pp. 277-281
-
-
Calignano, A.1
La Rana, G.2
Giuffrida, A.3
Piomelli, D.4
-
10
-
-
0037369856
-
A role for TRPV1 in bradykinin-induced excitation of vagal airway afferent nerve terminals
-
Carr M.J., Kollarik M., Meeker S.N., and Undem B.J. A role for TRPV1 in bradykinin-induced excitation of vagal airway afferent nerve terminals. J. Pharmacol. Exp. Ther. 304 (2003) 1275-1279
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 1275-1279
-
-
Carr, M.J.1
Kollarik, M.2
Meeker, S.N.3
Undem, B.J.4
-
11
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
12
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham D.E. TRP channels as cellular sensors. Nature 426 (2003) 517-524
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
13
-
-
1842529993
-
Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1
-
Contassot E., Tenan M., Schnuriger V., Pelte M.F., and Dietrich P.Y. Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1. Gynecol. Oncol. 93 (2004) 182-188
-
(2004)
Gynecol. Oncol.
, vol.93
, pp. 182-188
-
-
Contassot, E.1
Tenan, M.2
Schnuriger, V.3
Pelte, M.F.4
Dietrich, P.Y.5
-
14
-
-
4744350135
-
Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels
-
De Petrocellis L., Chu C.J., Moriello A.S., Kellner J.C., Walker J.M., and Di Marzo V. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. Br. J. Pharmacol. 143 (2004) 251-256
-
(2004)
Br. J. Pharmacol.
, vol.143
, pp. 251-256
-
-
De Petrocellis, L.1
Chu, C.J.2
Moriello, A.S.3
Kellner, J.C.4
Walker, J.M.5
Di Marzo, V.6
-
15
-
-
0028317057
-
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes
-
Devane W.A., and Axelrod J. Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. Proc. Natl. Acad. Sci. USA 91 (1994) 6698-6701
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6698-6701
-
-
Devane, W.A.1
Axelrod, J.2
-
16
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane W.A., Hanus L., Breuer A., Pertwee R.G., Stevenson L.A., Griffin G., Gibson D., Mandelbaum A., Etinger A., and Mechoulam R. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 (1992) 1946-1949
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
17
-
-
0030742250
-
Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture
-
Docherty R.J., Yeats J.C., and Piper A.S. Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture. Br. J. Pharmacol. 121 (1997) 1461-1467
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 1461-1467
-
-
Docherty, R.J.1
Yeats, J.C.2
Piper, A.S.3
-
18
-
-
19944428963
-
Discovery of potent, orally available vanilloid receptor-1 antagonists: Structure-activity relationship of N-aryl cinnamides
-
Doherty E.M., Fotsch C., Bo Y., Chakrabarti P.P., Chen N., Gavva N., Han N., Kelly M.G., Kincaid J., Klionsky L., Liu Q., Ognyanov V.I., et al. Discovery of potent, orally available vanilloid receptor-1 antagonists: Structure-activity relationship of N-aryl cinnamides. J. Med. Chem. 48 (2005) 71-90
-
(2005)
J. Med. Chem.
, vol.48
, pp. 71-90
-
-
Doherty, E.M.1
Fotsch, C.2
Bo, Y.3
Chakrabarti, P.P.4
Chen, N.5
Gavva, N.6
Han, N.7
Kelly, M.G.8
Kincaid, J.9
Klionsky, L.10
Liu, Q.11
Ognyanov, V.I.12
-
19
-
-
0027532297
-
Bradykinin and inflammatory pain
-
Dray A., and Perkins M. Bradykinin and inflammatory pain. Trends Neurosci. 3 (1993) 99-104
-
(1993)
Trends Neurosci.
, vol.3
, pp. 99-104
-
-
Dray, A.1
Perkins, M.2
-
20
-
-
1842559782
-
Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice
-
Ferreira J., da Silva G.L., and Calixto J.B. Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice. Br. J. Pharmacol. 141 (2004) 787-794
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 787-794
-
-
Ferreira, J.1
da Silva, G.L.2
Calixto, J.B.3
-
21
-
-
0027133614
-
Bradykinin initiates cytokine-mediated inflammatory hyperalgesia
-
Ferreira S.H., Lorenzetti B.B., and Poole S. Bradykinin initiates cytokine-mediated inflammatory hyperalgesia. Br. J. Pharmacol. 110 (1993) 1227-1231
-
(1993)
Br. J. Pharmacol.
, vol.110
, pp. 1227-1231
-
-
Ferreira, S.H.1
Lorenzetti, B.B.2
Poole, S.3
-
22
-
-
0035955607
-
Cytochrome p450 and vascular homeostasis
-
Fleming I. Cytochrome p450 and vascular homeostasis. Circ. Res. 89 (2001) 753-762
-
(2001)
Circ. Res.
, vol.89
, pp. 753-762
-
-
Fleming, I.1
-
23
-
-
0024360410
-
Bradykinin stimulates phosphoinositide hydrolysis and mobilization of arachidonic acid in dorsal root ganglion neurons
-
Gammon C.M., Allen A.C., and Morell P. Bradykinin stimulates phosphoinositide hydrolysis and mobilization of arachidonic acid in dorsal root ganglion neurons. J. Neurochem. 53 (1989) 95-101
-
(1989)
J. Neurochem.
, vol.53
, pp. 95-101
-
-
Gammon, C.M.1
Allen, A.C.2
Morell, P.3
-
24
-
-
2442498381
-
Molecular determinants of vanilloid sensitivity in TRPV1
-
Gavva N.R., Klionsky L., Qu Y., Shi L., Tamir R., Edenson S., Zhang T.J., Viswanadhan V.N., Toth A., Pearce L.V., Vanderah T.W., Porreca F., et al. Molecular determinants of vanilloid sensitivity in TRPV1. J. Biol. Chem. 279 (2004) 20283-20295
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20283-20295
-
-
Gavva, N.R.1
Klionsky, L.2
Qu, Y.3
Shi, L.4
Tamir, R.5
Edenson, S.6
Zhang, T.J.7
Viswanadhan, V.N.8
Toth, A.9
Pearce, L.V.10
Vanderah, T.W.11
Porreca, F.12
-
25
-
-
20144362216
-
AMG 9810 [(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a Novel Vanilloid Receptor 1 (TRPV1) Antagonist with Antihyperalgesic Properties
-
Gavva N.R., Tamir R., Qu Y., Klionsky L., Zhang T.J., Immke D., Wang J., Zhu D., Vanderah T.W., Porreca F., Doherty E.M., Norman M.H., et al. AMG 9810 [(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a Novel Vanilloid Receptor 1 (TRPV1) Antagonist with Antihyperalgesic Properties. J. Pharmacol. Exp. Ther. 313 (2005) 474-484
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.313
, pp. 474-484
-
-
Gavva, N.R.1
Tamir, R.2
Qu, Y.3
Klionsky, L.4
Zhang, T.J.5
Immke, D.6
Wang, J.7
Zhu, D.8
Vanderah, T.W.9
Porreca, F.10
Doherty, E.M.11
Norman, M.H.12
-
26
-
-
20144388484
-
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain
-
Ghilardi J.R., Rohrich H., Lindsay T.H., Sevcik M.A., Schwei M.J., Kubota K., Halvorson K.G., Poblete J., Chaplan S.R., Dubin A.E., Carruthers N.I., Swanson D., et al. Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. J. Neurosci. 25 (2005) 3126-3131
-
(2005)
J. Neurosci.
, vol.25
, pp. 3126-3131
-
-
Ghilardi, J.R.1
Rohrich, H.2
Lindsay, T.H.3
Sevcik, M.A.4
Schwei, M.J.5
Kubota, K.6
Halvorson, K.G.7
Poblete, J.8
Chaplan, S.R.9
Dubin, A.E.10
Carruthers, N.I.11
Swanson, D.12
-
27
-
-
7044221810
-
Characterization of the human HCN1 channel and its inhibition by capsazepine
-
Gill C.H., Randall A., Bates S.A., Hill K., Owen D., Larkman P.M., Cairns W., Yusaf S.P., Murdock P.R., Strijbos P.J., Powell A.J., Benham C.D., et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br. J. Pharmacol. 143 (2004) 411-421
-
(2004)
Br. J. Pharmacol.
, vol.143
, pp. 411-421
-
-
Gill, C.H.1
Randall, A.2
Bates, S.A.3
Hill, K.4
Owen, D.5
Larkman, P.M.6
Cairns, W.7
Yusaf, S.P.8
Murdock, P.R.9
Strijbos, P.J.10
Powell, A.J.11
Benham, C.D.12
-
28
-
-
10744220213
-
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist
-
Gunthorpe M.J., Rami H.K., Jerman J.C., Smart D., Gill C.H., Soffin E.M., Luis Hannan S., Lappin S.C., Egerton J., Smith G.D., Worby A., Howett L., et al. Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist. Neuropharmacology 46 (2004) 133-149
-
(2004)
Neuropharmacology
, vol.46
, pp. 133-149
-
-
Gunthorpe, M.J.1
Rami, H.K.2
Jerman, J.C.3
Smart, D.4
Gill, C.H.5
Soffin, E.M.6
Luis Hannan, S.7
Lappin, S.C.8
Egerton, J.9
Smith, G.D.10
Worby, A.11
Howett, L.12
-
29
-
-
0025743390
-
Discharge patterns of human C-fibers induced by itching and burning stimuli
-
Handwerker H.O., Forster C., and Kirchhoff C. Discharge patterns of human C-fibers induced by itching and burning stimuli. J. Neurophysiol. 66 (1991) 307-315
-
(1991)
J. Neurophysiol.
, vol.66
, pp. 307-315
-
-
Handwerker, H.O.1
Forster, C.2
Kirchhoff, C.3
-
30
-
-
0031878159
-
Neural injury, repair, and adaptation in the GI tract. II. The elusive action of capsaicin on the vagus nerve
-
Holzer P. Neural injury, repair, and adaptation in the GI tract. II. The elusive action of capsaicin on the vagus nerve. Am. J. Physiol. 275 (1998) G8-G13
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Holzer, P.1
-
31
-
-
0028173267
-
Behavioural effects of intraplantar injection of inflammatory mediators in the rat
-
Hong Y., and Abbott F.V. Behavioural effects of intraplantar injection of inflammatory mediators in the rat. Neuroscience 63 (1994) 827-836
-
(1994)
Neuroscience
, vol.63
, pp. 827-836
-
-
Hong, Y.1
Abbott, F.V.2
-
32
-
-
0028987880
-
Pharmacology of cannabinoid receptors
-
Howlett A.C. Pharmacology of cannabinoid receptors. Annu. Rev. Pharmacol. Toxicol. 35 (1995) 607-634
-
(1995)
Annu. Rev. Pharmacol. Toxicol.
, vol.35
, pp. 607-634
-
-
Howlett, A.C.1
-
33
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang S.M., Bisogno T., Trevisani M., Al-Hayani A., De Petrocellis L., Fezza F., Tognetto M., Petros T.J., Krey J.F., Chu C.J., Miller J.D., Davies S.N., et al. An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc. Natl. Acad. Sci. USA 99 (2002) 8400-8405
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
Al-Hayani, A.4
De Petrocellis, L.5
Fezza, F.6
Tognetto, M.7
Petros, T.J.8
Krey, J.F.9
Chu, C.J.10
Miller, J.D.11
Davies, S.N.12
-
34
-
-
0036605663
-
Hot channels in airways: Pharmacology of the vanilloid receptor
-
Hwang S.W., and Oh U. Hot channels in airways: Pharmacology of the vanilloid receptor. Curr. Opin. Pharmacol. 2 (2002) 235-242
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 235-242
-
-
Hwang, S.W.1
Oh, U.2
-
35
-
-
0004906771
-
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
-
Hwang S.W., Cho H., Kwak J., Lee S.Y., Kang C.J., Jung J., Cho S., Min K.H., Suh Y.G., Kim D., and Oh U. Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances. Proc. Natl. Acad. Sci. USA 97 (2000) 6155-6160
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6155-6160
-
-
Hwang, S.W.1
Cho, H.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Jung, J.6
Cho, S.7
Min, K.H.8
Suh, Y.G.9
Kim, D.10
Oh, U.11
-
36
-
-
0030028233
-
Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
-
Imig J.D., Zou A.P., Stec D.E., Harder D.R., Falck J.R., and Roman R.J. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am. J. Physiol. 270 (1996) R217-R227
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Imig, J.D.1
Zou, A.P.2
Stec, D.E.3
Harder, D.R.4
Falck, J.R.5
Roman, R.J.6
-
37
-
-
0038752614
-
The principle of gating charge movement in a voltage-dependent K+ channel
-
Jiang Y., Ruta V., Chen J., Lee A., and MacKinnon R. The principle of gating charge movement in a voltage-dependent K+ channel. Nature 423 (2003) 42-48
-
(2003)
Nature
, vol.423
, pp. 42-48
-
-
Jiang, Y.1
Ruta, V.2
Chen, J.3
Lee, A.4
MacKinnon, R.5
-
38
-
-
0038076054
-
X-ray structure of a voltage-dependent K+ channel
-
Jiang Y., Lee A., Chen J., Ruta V., Cadene M., Chait B.T., and MacKinnon R. X-ray structure of a voltage-dependent K+ channel. Nature 423 (2003) 33-41
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
MacKinnon, R.7
-
39
-
-
0036183319
-
Molecular basis for species-specific sensitivity to "hot" chili peppers
-
Jordt S.E., and Julius D. Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108 (2002) 421-430
-
(2002)
Cell
, vol.108
, pp. 421-430
-
-
Jordt, S.E.1
Julius, D.2
-
40
-
-
0037581663
-
Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel
-
Jung J., Hwang S.W., Kwak J., Lee S.Y., Kang C.J., Kim W.B., Kim D., and Oh U. Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel. J. Neurosci. 19 (1999) 529-538
-
(1999)
J. Neurosci.
, vol.19
, pp. 529-538
-
-
Jung, J.1
Hwang, S.W.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Kim, W.B.6
Kim, D.7
Oh, U.8
-
41
-
-
0037113918
-
Agonist recognition sites in the cytosolic tails of vanilloid receptor 1
-
Jung J., Lee S.-Y., Hwang S.W., Cho H., Shin J., Kang Y.-S., Kim S., and Oh U. Agonist recognition sites in the cytosolic tails of vanilloid receptor 1. J. Biol. Chem. 277 (2002) 44448-44454
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44448-44454
-
-
Jung, J.1
Lee, S.-Y.2
Hwang, S.W.3
Cho, H.4
Shin, J.5
Kang, Y.-S.6
Kim, S.7
Oh, U.8
-
43
-
-
2342466078
-
Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons
-
Kim B.M., Lee S.H., Shim W.S., and Oh U. Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons. Neurosci. Lett. 361 (2004) 159-162
-
(2004)
Neurosci. Lett.
, vol.361
, pp. 159-162
-
-
Kim, B.M.1
Lee, S.H.2
Shim, W.S.3
Oh, U.4
-
44
-
-
0024490404
-
G-protein βγ_-subunits activate the cardiac muscarinic K+-channel via phosphorylase A2
-
Kim D., Lewis D.L., Graziadei L., Neer E.J., Bar-Sagi D., and Clapham D.E. G-protein βγ_-subunits activate the cardiac muscarinic K+-channel via phosphorylase A2. Nature 337 (1989) 557-560
-
(1989)
Nature
, vol.337
, pp. 557-560
-
-
Kim, D.1
Lewis, D.L.2
Graziadei, L.3
Neer, E.J.4
Bar-Sagi, D.5
Clapham, D.E.6
-
45
-
-
0027310587
-
Conditioning of histamine by bradykinin alters responses of rat nociceptor and human itch sensation
-
Koppert W., Reeh P.W., and Handwerker H.O. Conditioning of histamine by bradykinin alters responses of rat nociceptor and human itch sensation. Neurosci. Lett. 152 (1993) 117-120
-
(1993)
Neurosci. Lett.
, vol.152
, pp. 117-120
-
-
Koppert, W.1
Reeh, P.W.2
Handwerker, H.O.3
-
46
-
-
0034924224
-
Interactions of histamine and bradykinin on polymodal C-fibres in isolated rat skin
-
Koppert W., Martus P., and Reeh P.W. Interactions of histamine and bradykinin on polymodal C-fibres in isolated rat skin. Eur. J. Pain 5 (2001) 97-106
-
(2001)
Eur. J. Pain
, vol.5
, pp. 97-106
-
-
Koppert, W.1
Martus, P.2
Reeh, P.W.3
-
47
-
-
0026320329
-
Sensitizing effects of bradykinin on the heat responses of the visceral nociceptor
-
Kumazawa T., Mizumura K., Minagawa M., and Tsujii Y. Sensitizing effects of bradykinin on the heat responses of the visceral nociceptor. J. Neurophysiol. 66 (1991) 1819-1824
-
(1991)
J. Neurophysiol.
, vol.66
, pp. 1819-1824
-
-
Kumazawa, T.1
Mizumura, K.2
Minagawa, M.3
Tsujii, Y.4
-
48
-
-
0030001452
-
EP receptor subtypes implicated in the PGE2-induced sensitization of polymodal receptors in response to bradykinin and heat
-
Kumazawa T., Mizumura K., Koda H., and Fukusako H. EP receptor subtypes implicated in the PGE2-induced sensitization of polymodal receptors in response to bradykinin and heat. J. Neurophysiol. 75 (1996) 2361-2368
-
(1996)
J. Neurophysiol.
, vol.75
, pp. 2361-2368
-
-
Kumazawa, T.1
Mizumura, K.2
Koda, H.3
Fukusako, H.4
-
49
-
-
0032101210
-
A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: Evidence for an endogenous capsaicin-like substance
-
Kwak J.Y., Jung J.Y., Hwang S.W., Lee W.T., and Oh U. A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: Evidence for an endogenous capsaicin-like substance. Neuroscience 86 (1998) 619-626
-
(1998)
Neuroscience
, vol.86
, pp. 619-626
-
-
Kwak, J.Y.1
Jung, J.Y.2
Hwang, S.W.3
Lee, W.T.4
Oh, U.5
-
51
-
-
0028031630
-
Guinea pig histamine H1 receptor. II. Stable expression in Chinese hamster ovary cells reveals the interaction with three major signal transduction pathways
-
Leurs R., Traiffort E., Arrang J.M., Tardivel-Lacombe J., Ruat M., and Schwartz J.C. Guinea pig histamine H1 receptor. II. Stable expression in Chinese hamster ovary cells reveals the interaction with three major signal transduction pathways. J. Neurochem. 62 (1994) 519-527
-
(1994)
J. Neurochem.
, vol.62
, pp. 519-527
-
-
Leurs, R.1
Traiffort, E.2
Arrang, J.M.3
Tardivel-Lacombe, J.4
Ruat, M.5
Schwartz, J.C.6
-
52
-
-
0021286902
-
Leukotrien B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes
-
Levine J.D., Lau W., and Kwiat G. Leukotrien B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes. Science 225 (1984) 743-745
-
(1984)
Science
, vol.225
, pp. 743-745
-
-
Levine, J.D.1
Lau, W.2
Kwiat, G.3
-
53
-
-
0034912392
-
Nociceptor activation and protein extravasation induced by inflammatory mediators in human skin
-
Lischetzki G., Rukwied R., Handwerker H.O., and Schmelz M. Nociceptor activation and protein extravasation induced by inflammatory mediators in human skin. Eur. J. Pain 5 (2001) 49-57
-
(2001)
Eur. J. Pain
, vol.5
, pp. 49-57
-
-
Lischetzki, G.1
Rukwied, R.2
Handwerker, H.O.3
Schmelz, M.4
-
54
-
-
0028123430
-
A rapid capsaicin-activated current in rat trigeminal ganglion neurons
-
Liu L., and Simon S.A. A rapid capsaicin-activated current in rat trigeminal ganglion neurons. Proc. Natl. Acad. Sci. USA 91 (1994) 738-741
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 738-741
-
-
Liu, L.1
Simon, S.A.2
-
55
-
-
0030792361
-
Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia
-
Liu L., and Simon S.A. Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia. Neurosci. Lett. 228 (1997) 29-32
-
(1997)
Neurosci. Lett.
, vol.228
, pp. 29-32
-
-
Liu, L.1
Simon, S.A.2
-
56
-
-
0034644769
-
Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors
-
Maccarrone M., Lorenzon T., Bari M., Melino G., and Finazzi-Agro A. Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J. Biol. Chem. 275 (2000) 31938-31945
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31938-31945
-
-
Maccarrone, M.1
Lorenzon, T.2
Bari, M.3
Melino, G.4
Finazzi-Agro, A.5
-
57
-
-
0025134061
-
Properties of transdermal histamine iontophoresis: Differential effects of season, gender, and body region
-
Magerl W., Westerman R.A., Mohner B., and Handwerker H.O. Properties of transdermal histamine iontophoresis: Differential effects of season, gender, and body region. J. Invest. Dermatol. 94 (1990) 347-352
-
(1990)
J. Invest. Dermatol.
, vol.94
, pp. 347-352
-
-
Magerl, W.1
Westerman, R.A.2
Mohner, B.3
Handwerker, H.O.4
-
58
-
-
0023821187
-
Leukotriene B4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat
-
Martin H.A., Basbaum A.I., Goetzl E.J., and Levine J.D. Leukotriene B4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat. J. Neurophysiol. 60 (1988) 438-445
-
(1988)
J. Neurophysiol.
, vol.60
, pp. 438-445
-
-
Martin, H.A.1
Basbaum, A.I.2
Goetzl, E.J.3
Levine, J.D.4
-
59
-
-
0035104516
-
20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure
-
McGiff J.C., and Quilley J. 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure. Curr. Opin. Nephrol. Hypertens. 10 (2001) 231-237
-
(2001)
Curr. Opin. Nephrol. Hypertens.
, vol.10
, pp. 231-237
-
-
McGiff, J.C.1
Quilley, J.2
-
60
-
-
0026716548
-
G-protein mediation in nociceptive signal transduction: An investigation into the excitatory action of bradykinin in a rat sensory neurons
-
McGuirk S.M., and Dolphin A.C. G-protein mediation in nociceptive signal transduction: An investigation into the excitatory action of bradykinin in a rat sensory neurons. Neuroscience 49 (1992) 117-128
-
(1992)
Neuroscience
, vol.49
, pp. 117-128
-
-
McGuirk, S.M.1
Dolphin, A.C.2
-
61
-
-
0032531040
-
Inflammatory mediators sensitize acutely axotomized nerve fibers to mechanical stimulation in the rat
-
Michaelis M., Vogel C., Blenk K.H., Arnarson A., and Janig W. Inflammatory mediators sensitize acutely axotomized nerve fibers to mechanical stimulation in the rat. J. Neurosci. 18 (1998) 7581-7587
-
(1998)
J. Neurosci.
, vol.18
, pp. 7581-7587
-
-
Michaelis, M.1
Vogel, C.2
Blenk, K.H.3
Arnarson, A.4
Janig, W.5
-
62
-
-
18244402941
-
A unified nomenclature for the superfamily of TRP cation channels
-
Montell C., Birnbaumer L., Flockerzi V., Bindels R.J., Bruford E.A., Caterina M.J., Clapham D.E., Harteneck C., Heller S., and Julius D. A unified nomenclature for the superfamily of TRP cation channels. Mol. Cell 9 (2002) 229-231
-
(2002)
Mol. Cell
, vol.9
, pp. 229-231
-
-
Montell, C.1
Birnbaumer, L.2
Flockerzi, V.3
Bindels, R.J.4
Bruford, E.A.5
Caterina, M.J.6
Clapham, D.E.7
Harteneck, C.8
Heller, S.9
Julius, D.10
-
63
-
-
0037066069
-
Characterization of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones
-
Nicolson T.A., Bevan S., and Richards C.D. Characterization of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones. Neuroscience 110 (2002) 329-338
-
(2002)
Neuroscience
, vol.110
, pp. 329-338
-
-
Nicolson, T.A.1
Bevan, S.2
Richards, C.D.3
-
64
-
-
0742288219
-
TRPV4 calcium entry channel: A paradigm for gating diversity
-
Nilius B., Vriens J., Prenen J., Droogmans G., and Voets T. TRPV4 calcium entry channel: A paradigm for gating diversity. Am. J. Physiol. Cell Physiol. 286 (2004) C195-C205
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.286
-
-
Nilius, B.1
Vriens, J.2
Prenen, J.3
Droogmans, G.4
Voets, T.5
-
65
-
-
9244243039
-
Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons
-
Oh U., Hwang S.W., and Kim D. Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons. J. Neurosci. 16 (1996) 1659-1667
-
(1996)
J. Neurosci.
, vol.16
, pp. 1659-1667
-
-
Oh, U.1
Hwang, S.W.2
Kim, D.3
-
66
-
-
0023221322
-
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells
-
Piomelli D., Volterra A., Dale N., Siegelbaum S.A., Kandel E.R., Schwartz J.H., and Belardetti F. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature 328 (1987) 38-43
-
(1987)
Nature
, vol.328
, pp. 38-43
-
-
Piomelli, D.1
Volterra, A.2
Dale, N.3
Siegelbaum, S.A.4
Kandel, E.R.5
Schwartz, J.H.6
Belardetti, F.7
-
67
-
-
0038128285
-
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)- carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo characterization in rat models of inflammatory and neuropathic pain
-
Pomonis J.D., Harrison J.E., Mark L., Bristol D.R., Valenzano K.J., and Walker K. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)- carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo characterization in rat models of inflammatory and neuropathic pain. J. Pharmacol. Exp. Ther. 306 (2003) 387-393
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 387-393
-
-
Pomonis, J.D.1
Harrison, J.E.2
Mark, L.3
Bristol, D.R.4
Valenzano, K.J.5
Walker, K.6
-
68
-
-
0009832893
-
Sensory receptors in a mammalian skin-nerve in vitro preparation
-
Reeh P.W. Sensory receptors in a mammalian skin-nerve in vitro preparation. Prog. Brain Res. 74 (1988) 271-276
-
(1988)
Prog. Brain Res.
, vol.74
, pp. 271-276
-
-
Reeh, P.W.1
-
69
-
-
0034589732
-
Nociceptor excitation by thermal sensitization-a hypothesis
-
Reeh P.W., and Petho G. Nociceptor excitation by thermal sensitization-a hypothesis. Prog. Brain Res. 129 (2000) 39-50
-
(2000)
Prog. Brain Res.
, vol.129
, pp. 39-50
-
-
Reeh, P.W.1
Petho, G.2
-
70
-
-
85004846302
-
Plasma histamine concentrations in atopic eczema
-
Ring J. Plasma histamine concentrations in atopic eczema. Clin. Allergy 13 (1983) 545-552
-
(1983)
Clin. Allergy
, vol.13
, pp. 545-552
-
-
Ring, J.1
-
71
-
-
0036080081
-
P-450 metabolites of arachidonic acid in the control of cardiovascular function
-
Roman R.J. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol. Rev. 82 (2002) 131-185
-
(2002)
Physiol. Rev.
, vol.82
, pp. 131-185
-
-
Roman, R.J.1
-
72
-
-
13644262070
-
Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle
-
Rousseau E., Cloutier M., Morin C., and Proteau S. Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle. Am. J. Physiol. Lung Cell Mol. Physiol. 288 (2005) L460-L470
-
(2005)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.288
-
-
Rousseau, E.1
Cloutier, M.2
Morin, C.3
Proteau, S.4
-
73
-
-
0020698184
-
Cutaneous histamine levels and histamine releasability from the skin in atopic dermatitis and hyper-IgE-syndrome
-
Ruzicka T., and Gluck S. Cutaneous histamine levels and histamine releasability from the skin in atopic dermatitis and hyper-IgE-syndrome. Arch. Dermatol. Res. 275 (1983) 41-44
-
(1983)
Arch. Dermatol. Res.
, vol.275
, pp. 41-44
-
-
Ruzicka, T.1
Gluck, S.2
-
74
-
-
0035940785
-
The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat
-
Sanchez J.F., Krause J.E., and Cortright D.N. The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat. Neuroscience 107 (2001) 373-381
-
(2001)
Neuroscience
, vol.107
, pp. 373-381
-
-
Sanchez, J.F.1
Krause, J.E.2
Cortright, D.N.3
-
75
-
-
0030851736
-
Specific C-receptors for itch in human skin
-
Schmelz M., Schmidt R., Bickel A., Handwerker H.O., and Torebjork H.E. Specific C-receptors for itch in human skin. J. Neurosci. 17 (1997) 8003-8008
-
(1997)
J. Neurosci.
, vol.17
, pp. 8003-8008
-
-
Schmelz, M.1
Schmidt, R.2
Bickel, A.3
Handwerker, H.O.4
Torebjork, H.E.5
-
76
-
-
0037541581
-
Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens
-
Schmelz M., Schmidt R., Weidner C., Hilliges M., Torebjork H.E., and Handwerker H.O. Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens. J. Neurophysiol. 89 (2003) 2441-2448
-
(2003)
J. Neurophysiol.
, vol.89
, pp. 2441-2448
-
-
Schmelz, M.1
Schmidt, R.2
Weidner, C.3
Hilliges, M.4
Torebjork, H.E.5
Handwerker, H.O.6
-
77
-
-
0034723256
-
Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal domain suggests functional divergence among capsaicin receptor subtypes
-
Schumacher M.A., Moff I., Sudanagunta S.P., and Levine J.D. Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal domain suggests functional divergence among capsaicin receptor subtypes. J. Biol. Chem. 275 (2000) 2756-2762
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2756-2762
-
-
Schumacher, M.A.1
Moff, I.2
Sudanagunta, S.P.3
Levine, J.D.4
-
78
-
-
8844262481
-
Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: A novel mechanism involved in myogenic constriction
-
Scotland R.S., Chauhan S., Davis C., De Felipe C., Hunt S., Kabir J., Kotsonis P., Oh U., and Ahluwalia A. Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: A novel mechanism involved in myogenic constriction. Circ. Res. 95 (2004) 1027-1034
-
(2004)
Circ. Res.
, vol.95
, pp. 1027-1034
-
-
Scotland, R.S.1
Chauhan, S.2
Davis, C.3
De Felipe, C.4
Hunt, S.5
Kabir, J.6
Kotsonis, P.7
Oh, U.8
Ahluwalia, A.9
-
79
-
-
0036894895
-
Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin
-
Seabrook G.R., Sutton K.G., Jarolimek W., Hollingworth G.J., Teague S., Webb J., Clark N., Boyce S., Kerby J., Ali Z., Chou M., Middleton R., et al. Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin. J. Pharmacol. Exp. Ther. 303 (2002) 1052-1060
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, pp. 1052-1060
-
-
Seabrook, G.R.1
Sutton, K.G.2
Jarolimek, W.3
Hollingworth, G.J.4
Teague, S.5
Webb, J.6
Clark, N.7
Boyce, S.8
Kerby, J.9
Ali, Z.10
Chou, M.11
Middleton, R.12
-
80
-
-
0141726847
-
Essential role of mitochondrial permeability transition in vanilloid receptor 1-dependent cell death of sensory neurons
-
Shin C.Y., Shin J., Kim B.M., Wang M.H., Jang J.H., Surh Y.J., and Oh U. Essential role of mitochondrial permeability transition in vanilloid receptor 1-dependent cell death of sensory neurons. Mol. Cell. Neurosci. 24 (2003) 57-68
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 57-68
-
-
Shin, C.Y.1
Shin, J.2
Kim, B.M.3
Wang, M.H.4
Jang, J.H.5
Surh, Y.J.6
Oh, U.7
-
81
-
-
0037162482
-
Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia
-
Shin J., Cho H., Hwang S.W., Jung J., Shin C.Y., Lee S.Y., Kim S.H., Lee M.G., Choi Y.H., Kim J., Haber N.A., Reichling D.B., et al. Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc. Natl. Acad. Sci. USA 99 (2002) 10150-10155
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10150-10155
-
-
Shin, J.1
Cho, H.2
Hwang, S.W.3
Jung, J.4
Shin, C.Y.5
Lee, S.Y.6
Kim, S.H.7
Lee, M.G.8
Choi, Y.H.9
Kim, J.10
Haber, N.A.11
Reichling, D.B.12
-
82
-
-
0035895716
-
Differences in sensitivity of vanilloid receptor 1 transfected to human embryonic kidney cells and capsaicin-activated channels in cultured rat dorsal root ganglion neurons to capsaicin receptor agonists
-
Shin J.S., Wang M.H., Hwang S.W., Cho H., Cho S.Y., Kwon M.J., Lee S.Y., and Oh U. Differences in sensitivity of vanilloid receptor 1 transfected to human embryonic kidney cells and capsaicin-activated channels in cultured rat dorsal root ganglion neurons to capsaicin receptor agonists. Neurosci. Lett. 299 (2001) 135-139
-
(2001)
Neurosci. Lett.
, vol.299
, pp. 135-139
-
-
Shin, J.S.1
Wang, M.H.2
Hwang, S.W.3
Cho, H.4
Cho, S.Y.5
Kwon, M.J.6
Lee, S.Y.7
Oh, U.8
-
84
-
-
0024351831
-
Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin
-
Simone D.A., Baumann T.K., and Lamotte R.H. Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain 38 (1989) 99-107
-
(1989)
Pain
, vol.38
, pp. 99-107
-
-
Simone, D.A.1
Baumann, T.K.2
Lamotte, R.H.3
-
85
-
-
0242581917
-
Neurophysiology of pruritus: Cutaneous elicitation of itch
-
Stander S., Steinhoff M., Schmelz M., Weisshaar E., Metze D., and Luger T. Neurophysiology of pruritus: Cutaneous elicitation of itch. Arch. Dermatol. 139 (2003) 1463-1470
-
(2003)
Arch. Dermatol.
, vol.139
, pp. 1463-1470
-
-
Stander, S.1
Steinhoff, M.2
Schmelz, M.3
Weisshaar, E.4
Metze, D.5
Luger, T.6
-
86
-
-
0029020352
-
A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro
-
Steen K.H., Steen A.E., and Reeh P.W. A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro. J. Neurosci. 15 (1995) 3982-3989
-
(1995)
J. Neurosci.
, vol.15
, pp. 3982-3989
-
-
Steen, K.H.1
Steen, A.E.2
Reeh, P.W.3
-
87
-
-
0344064842
-
Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects
-
Suh Y.G., Lee Y.S., Min K.H., Park O.H., Seung H.S., Kim H.D., Park H.G., Choi J., Lee J., Kang S.W., Oh U.T., Koo J.Y., et al. Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects. Bioorg. Med. Chem. Lett. 13 (2003) 4389-4393
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 4389-4393
-
-
Suh, Y.G.1
Lee, Y.S.2
Min, K.H.3
Park, O.H.4
Seung, H.S.5
Kim, H.D.6
Park, H.G.7
Choi, J.8
Lee, J.9
Kang, S.W.10
Oh, U.T.11
Koo, J.Y.12
-
88
-
-
10744226592
-
4-(2-pyridyl)piperazine-1-carboxamides: Potent vanilloid receptor 1 antagonists
-
Sun Q., Tafesse L., Islam K., Zhou X., Victory S.F., Zhang C., Hachicha M., Schmid L.A., Patel A., Rotshteyn Y., Valenzano K.J., Kyle D.J., et al. 4-(2-pyridyl)piperazine-1-carboxamides: Potent vanilloid receptor 1 antagonists. Bioorg. Med. Chem. Lett. 13 (2003) 3611-3616
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 3611-3616
-
-
Sun, Q.1
Tafesse, L.2
Islam, K.3
Zhou, X.4
Victory, S.F.5
Zhang, C.6
Hachicha, M.7
Schmid, L.A.8
Patel, A.9
Rotshteyn, Y.10
Valenzano, K.J.11
Kyle, D.J.12
-
89
-
-
20144376596
-
Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist
-
Swanson D.M., Dubin A.E., Shah C., Nasser N., Chang L., Dax S.L., Jetter M., Breitenbucher J.G., Liu C., Mazur C., Lord B., Gonzales L., et al. Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist. J. Med. Chem. 48 (2005) 1857-1872
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1857-1872
-
-
Swanson, D.M.1
Dubin, A.E.2
Shah, C.3
Nasser, N.4
Chang, L.5
Dax, S.L.6
Jetter, M.7
Breitenbucher, J.G.8
Liu, C.9
Mazur, C.10
Lord, B.11
Gonzales, L.12
-
90
-
-
0025110892
-
Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes
-
Szallasi A., and Blumberg P.M. Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes. Brain Res. 524 (1990) 106-111
-
(1990)
Brain Res.
, vol.524
, pp. 106-111
-
-
Szallasi, A.1
Blumberg, P.M.2
-
91
-
-
0032970173
-
Vanilloid (Capsaicin) receptors and mechanisms
-
Szallasi A., and Blumberg P.M. Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol. Rev. 51 (1999) 159-212
-
(1999)
Pharmacol. Rev.
, vol.51
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
92
-
-
0028173216
-
Visualization by [3H]resiniferatoxin autoradiography of capsaicin-sensitive neurons in the rat, pig and man
-
Szallasi A., Blumberg P.M., Nilsson S., Hokfelt T., and Lundberg J.M. Visualization by [3H]resiniferatoxin autoradiography of capsaicin-sensitive neurons in the rat, pig and man. Eur. J. Pharmacol. 264 (1994) 217-221
-
(1994)
Eur. J. Pharmacol.
, vol.264
, pp. 217-221
-
-
Szallasi, A.1
Blumberg, P.M.2
Nilsson, S.3
Hokfelt, T.4
Lundberg, J.M.5
-
93
-
-
0032876069
-
The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons
-
Szallasi A., Blumberg P.M., Annicelli L.L., Krause J.E., and Cortright D.N. The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons. Mol. Pharmacol. 56 (1999) 581-587
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 581-587
-
-
Szallasi, A.1
Blumberg, P.M.2
Annicelli, L.L.3
Krause, J.E.4
Cortright, D.N.5
-
94
-
-
0002919601
-
Actions of capsaicin on sensory receptors
-
Wood J. (Ed), Academic Press, London
-
Szolcsanyi J. Actions of capsaicin on sensory receptors. In: Wood J. (Ed). "Actions of Capsaicin on Sensory Receptors" (1993), Academic Press, London 1-26
-
(1993)
"Actions of Capsaicin on Sensory Receptors"
, pp. 1-26
-
-
Szolcsanyi, J.1
-
95
-
-
0017226275
-
Sensory effects of capsaicin congeners II. Importance of chemical structure and pungency in desensitizing activity of capsaicin-type compounds
-
Szolcsanyi J., and Jancso-Gabor A. Sensory effects of capsaicin congeners II. Importance of chemical structure and pungency in desensitizing activity of capsaicin-type compounds. Drug Res. 26 (1976) 33-37
-
(1976)
Drug Res.
, vol.26
, pp. 33-37
-
-
Szolcsanyi, J.1
Jancso-Gabor, A.2
-
96
-
-
5144232587
-
Synthesis and evaluation of pyridazinylpiperazines as vanilloid receptor 1 antagonists
-
Tafesse L., Sun Q., Schmid L., Valenzano K.J., Rotshteyn Y., Su X., and Kyle D.J. Synthesis and evaluation of pyridazinylpiperazines as vanilloid receptor 1 antagonists. Bioorg. Med. Chem. Lett. 14 (2004) 5513-5519
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 5513-5519
-
-
Tafesse, L.1
Sun, Q.2
Schmid, L.3
Valenzano, K.J.4
Rotshteyn, Y.5
Su, X.6
Kyle, D.J.7
-
97
-
-
0024206340
-
Regulation of calcium homeostasis in sensory neurons by bradykinin
-
Thayer S.A., Perney T.M., and Miller R.J. Regulation of calcium homeostasis in sensory neurons by bradykinin. J. Neurosci. 8 (1988) 4089-4097
-
(1988)
J. Neurosci.
, vol.8
, pp. 4089-4097
-
-
Thayer, S.A.1
Perney, T.M.2
Miller, R.J.3
-
98
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M., Caterina M.J., Malmberg A.B., Rosen T.A., Gilbert H., Skinner K., Raumann B.E., Basbaum A.I., and Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21 (1998) 531-543
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
99
-
-
0038467306
-
N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. In vitro characterization and pharmacokinetic properties
-
Valenzano K.J., Grant E.R., Wu G., Hachicha M., Schmid L., Tafesse L., Sun Q., Rotshteyn Y., Francis J., Limberis J., Malik S., Whittemore E.R., et al. N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. In vitro characterization and pharmacokinetic properties. J. Pharmacol. Exp. Ther. 306 (2003) 377-386
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 377-386
-
-
Valenzano, K.J.1
Grant, E.R.2
Wu, G.3
Hachicha, M.4
Schmid, L.5
Tafesse, L.6
Sun, Q.7
Rotshteyn, Y.8
Francis, J.9
Limberis, J.10
Malik, S.11
Whittemore, E.R.12
-
100
-
-
0035173995
-
Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist
-
Wahl P., Foged C., Tullin S., and Thomsen C. Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist. Mol. Pharmacol. 59 (2001) 9-15
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 9-15
-
-
Wahl, P.1
Foged, C.2
Tullin, S.3
Thomsen, C.4
-
101
-
-
0028021842
-
The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin
-
Walpole C.S., Bevan S., Bovermann G., Boelsterli J.J., Breckenridge R., Davies J.W., Hughes G.A., James I., Oberer L., Winter J., and Wrigglesworth R. The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin. J. Med. Chem. 37 (1994) 1942-1954
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1942-1954
-
-
Walpole, C.S.1
Bevan, S.2
Bovermann, G.3
Boelsterli, J.J.4
Breckenridge, R.5
Davies, J.W.6
Hughes, G.A.7
James, I.8
Oberer, L.9
Winter, J.10
Wrigglesworth, R.11
-
103
-
-
0036783709
-
High affinity antagonists of the vanilloid receptor
-
Wang Y., Szabo T., Welter J.D., Toth A., Tran R., Lee J., Kang S.U., Suh Y.G., and Blumberg P.M. High affinity antagonists of the vanilloid receptor. Mol. Pharmacol. 62 (2002) 947-956
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 947-956
-
-
Wang, Y.1
Szabo, T.2
Welter, J.D.3
Toth, A.4
Tran, R.5
Lee, J.6
Kang, S.U.7
Suh, Y.G.8
Blumberg, P.M.9
-
104
-
-
0037900092
-
High-affinity partial agonists of the vanilloid receptor
-
Wang Y., Toth A., Tran R., Szabo T., Welter J.D., Blumberg P.M., Lee J., Kang S.U., and Lim J.O. High-affinity partial agonists of the vanilloid receptor. Mol. Pharmacol. 64 (2003) 325-333
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 325-333
-
-
Wang, Y.1
Toth, A.2
Tran, R.3
Szabo, T.4
Welter, J.D.5
Blumberg, P.M.6
Lee, J.7
Kang, S.U.8
Lim, J.O.9
-
105
-
-
0030070938
-
A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain
-
Ward L., Wright E., and McMahon S.B. A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain. Pain 64 (1996) 129-138
-
(1996)
Pain
, vol.64
, pp. 129-138
-
-
Ward, L.1
Wright, E.2
McMahon, S.B.3
-
106
-
-
0025031914
-
Application of liquid chromatography with on-line radiochemical detection to metabolism studies on a novel class of analgesics
-
Wehmeyer K.R., Kasting G.B., Powell J.H., Kuhlenbeck D.L., Underwood R.A., and Bowman L.A. Application of liquid chromatography with on-line radiochemical detection to metabolism studies on a novel class of analgesics. J. Pharm. Biomed. Anal. 8 (1990) 177-183
-
(1990)
J. Pharm. Biomed. Anal.
, vol.8
, pp. 177-183
-
-
Wehmeyer, K.R.1
Kasting, G.B.2
Powell, J.H.3
Kuhlenbeck, D.L.4
Underwood, R.A.5
Bowman, L.A.6
-
107
-
-
0025296259
-
Cellular mechanism of action of resiniferatoxin: A potent sensory neuron excitotoxin
-
Winter J., Dray A., Wood J.N., Yeats J.C., and Bevan S. Cellular mechanism of action of resiniferatoxin: A potent sensory neuron excitotoxin. Brain Res. 520 (1990) 131-140
-
(1990)
Brain Res.
, vol.520
, pp. 131-140
-
-
Winter, J.1
Dray, A.2
Wood, J.N.3
Yeats, J.C.4
Bevan, S.5
-
108
-
-
0023715884
-
Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture
-
Wood J.N., Winter J., James I.F., Rang H.P., Yeats J., and Bevan S. Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture. J. Neurosci. 8 (1988) 3208-3220
-
(1988)
J. Neurosci.
, vol.8
, pp. 3208-3220
-
-
Wood, J.N.1
Winter, J.2
James, I.F.3
Rang, H.P.4
Yeats, J.5
Bevan, S.6
-
109
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt P.M., Petersson J., Andersson D.A., Chuang H., Sorgard M., Di Marzo V., Julius D., and Hogestatt E.D. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400 (1999) 452-457
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sorgard, M.5
Di Marzo, V.6
Julius, D.7
Hogestatt, E.D.8
|