메뉴 건너뛰기




Volumn 86, Issue 2, 1998, Pages 619-626

A capsaicin-receptor antagonist, capsazepine, reduces inflammation- induced hyperalgesic responses in the rat: Evidence for an endogenous capsaicin-like substance

Author keywords

Capsaicin receptor; Capsazepine; Fos immunohistochemistry; Inflammation; Pain

Indexed keywords

CAPSAICIN; CAPSAZEPINE; CARRAGEENAN; HISTAMINE; SEROTONIN;

EID: 0032101210     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00012-8     Document Type: Article
Times cited : (101)

References (41)
  • 1
    • 0027499092 scopus 로고
    • C-fos expression in rat lumbar spinal cord following peripheral stimulation in adjuvant-induced arthritic and normal rats
    • Abbadie C., Besson J. M. c-fos expression in rat lumbar spinal cord following peripheral stimulation in adjuvant-induced arthritic and normal rats. Brain Res. 607:1993;195-204.
    • (1993) Brain Res. , vol.607 , pp. 195-204
    • Abbadie, C.1    Besson, J.M.2
  • 2
    • 0025318022 scopus 로고
    • Modulation of neurogenic inflammation: Novel approaches to inflammatory disease
    • Barnes P. J., Belvisi M. G., Rogers D. F. Modulation of neurogenic inflammation: novel approaches to inflammatory disease. Trends pharmac. Sci. 11:1990;185-189.
    • (1990) Trends Pharmac. Sci. , vol.11 , pp. 185-189
    • Barnes, P.J.1    Belvisi, M.G.2    Rogers, D.F.3
  • 3
    • 0027988505 scopus 로고
    • Protons: Small stimulants of capsaicin-sensitive sensory nerves
    • Bevan S., Geppetti P. Protons: small stimulants of capsaicin-sensitive sensory nerves. Trends Neurosci. 17:1994;509-512.
    • (1994) Trends Neurosci. , vol.17 , pp. 509-512
    • Bevan, S.1    Geppetti, P.2
  • 5
    • 0029034823 scopus 로고
    • Nerve growth factor (NGF) differentially regulates the chemosensitivity of adult rat cultured sensory neurons
    • Bevan S., Winter J. Nerve growth factor (NGF) differentially regulates the chemosensitivity of adult rat cultured sensory neurons. J. Neurosci. 15:1995;4918-4926.
    • (1995) J. Neurosci. , vol.15 , pp. 4918-4926
    • Bevan, S.1    Winter, J.2
  • 6
    • 0025297681 scopus 로고
    • Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat
    • Bullitt E. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J. comp. Neurol. 296:1990;517-530.
    • (1990) J. Comp. Neurol. , vol.296 , pp. 517-530
    • Bullitt, E.1
  • 7
    • 0028899240 scopus 로고
    • Indomethacin reduces both Krox-24 expression in the rat lumbar spinal cord and inflammatory signs following intraplantar carrageenan
    • Buritova J., Honore P., Besson J. M. Indomethacin reduces both Krox-24 expression in the rat lumbar spinal cord and inflammatory signs following intraplantar carrageenan. Brain Res. 674:1995;211-220.
    • (1995) Brain Res. , vol.674 , pp. 211-220
    • Buritova, J.1    Honore, P.2    Besson, J.M.3
  • 8
    • 0025369568 scopus 로고    scopus 로고
    • Differential effect of a chemical algogen on two nociceptive thresholds
    • Calvino B. Differential effect of a chemical algogen on two nociceptive thresholds. Physiol. Behav. 47:1997;907-910.
    • (1997) Physiol. Behav. , vol.47 , pp. 907-910
    • Calvino, B.1
  • 9
    • 0025718476 scopus 로고
    • Selective antagonism of capsaicin by capsazepine: Evidence for a spinal receptor site in capsaicin-induced antinociception
    • Dickenson A. H., Dray A. Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception. Br. J. Pharmac. 104:1991;1045-1049.
    • (1991) Br. J. Pharmac. , vol.104 , pp. 1045-1049
    • Dickenson, A.H.1    Dray, A.2
  • 10
    • 0023553720 scopus 로고
    • Subcutaneous formalin-induced activity of dorsal horn neurons in the rat: Differential response to an intrathecal opiate administered pre or post formalin
    • Dickenson A. H., Sullivan A. F. Subcutaneous formalin-induced activity of dorsal horn neurons in the rat: differential response to an intrathecal opiate administered pre or post formalin. Pain. 30:1987;349-360.
    • (1987) Pain , vol.30 , pp. 349-360
    • Dickenson, A.H.1    Sullivan, A.F.2
  • 11
    • 0026702932 scopus 로고
    • Neuropharmacological mechanisms of capsaicin and related substances
    • Dray A. Neuropharmacological mechanisms of capsaicin and related substances. Biochem. Pharmac. 44:1992;611-615.
    • (1992) Biochem. Pharmac. , vol.44 , pp. 611-615
    • Dray, A.1
  • 12
    • 0025215984 scopus 로고
    • Resiniferatoxin, a potent capsaicin-like stimulator of peripheral nociceptors in the neonatal rat tail in vitro
    • Dray A., Bettaney J., Forster P. Resiniferatoxin, a potent capsaicin-like stimulator of peripheral nociceptors in the neonatal rat tail in vitro. Br. J. Pharmac. 99:1990;323-326.
    • (1990) Br. J. Pharmac. , vol.99 , pp. 323-326
    • Dray, A.1    Bettaney, J.2    Forster, P.3
  • 13
    • 0017643233 scopus 로고    scopus 로고
    • The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brainstem stimulation in rats and cats
    • Dubuisson D., Dennis S. G. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brainstem stimulation in rats and cats. Pain. 4:1997;161-174.
    • (1997) Pain , vol.4 , pp. 161-174
    • Dubuisson, D.1    Dennis, S.G.2
  • 14
    • 0025882073 scopus 로고
    • The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: Correlation of nociceptive behavior and c-fos expression
    • Gogas K. R., Presley R. W., Levine J. D., Basbaum A. I. The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression. Neuroscience. 42:1991;617-628.
    • (1991) Neuroscience , vol.42 , pp. 617-628
    • Gogas, K.R.1    Presley, R.W.2    Levine, J.D.3    Basbaum, A.I.4
  • 15
    • 0025635779 scopus 로고
    • Changes of substance P-like immunoreactivity in the dorsal horn are associated with the phasic behavioral response to a formalin stimulus
    • Holland L. N., Goldstein B. D. Changes of substance P-like immunoreactivity in the dorsal horn are associated with the phasic behavioral response to a formalin stimulus. Brain Res. 537:1990;287-292.
    • (1990) Brain Res. , vol.537 , pp. 287-292
    • Holland, L.N.1    Goldstein, B.D.2
  • 16
    • 0025871477 scopus 로고
    • Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons
    • Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmac. Rev. 43:1991;143-201.
    • (1991) Pharmac. Rev. , vol.43 , pp. 143-201
    • Holzer, P.1
  • 17
    • 0028831620 scopus 로고
    • Carrageenin-evoked c-Fos expression in rat lumbar spinal cord: The effect of indomethacin
    • Honore P., Buritova J., Besson J. M. Carrageenin-evoked c-Fos expression in rat lumbar spinal cord: the effect of indomethacin. Eur. J. Pharmac. 272:1995;249-259.
    • (1995) Eur. J. Pharmac. , vol.272 , pp. 249-259
    • Honore, P.1    Buritova, J.2    Besson, J.M.3
  • 18
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabelled antibody (PAP) procedures
    • Hsu S., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
    • (1981) J. Histochem. Cytochem. , vol.29 , pp. 577-580
    • Hsu, S.1    Raine, L.2    Fanger, H.3
  • 19
    • 0023223448 scopus 로고
    • The formalin test in mice: Dissociation between inflammatory and non-inflammatory pain
    • Hunskaar S., Hole K. The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain. 30:1987;103-114.
    • (1987) Pain , vol.30 , pp. 103-114
    • Hunskaar, S.1    Hole, K.2
  • 20
    • 0023277535 scopus 로고
    • Induction of c-fos-like protein in spinal cord neurons following sensory stimulation
    • Hunt S. P., Pini A., Evans G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature. 328:1987;632-634.
    • (1987) Nature , vol.328 , pp. 632-634
    • Hunt, S.P.1    Pini, A.2    Evans, G.3
  • 21
    • 0025868408 scopus 로고
    • Neurogenic hyperalgesia: Psychophysical studies of underlying mechanisms
    • LaMotte R. H., Shain C. N., Sinone D. A., Tsai E. P. Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J. Neurophysiol. 66:1991;190-211.
    • (1991) J. Neurophysiol. , vol.66 , pp. 190-211
    • LaMotte, R.H.1    Shain, C.N.2    Sinone, D.A.3    Tsai, E.P.4
  • 22
    • 0025274415 scopus 로고
    • Chemosensitivity of fine afferents from rat skin in vitro
    • Lang E., Novak A., Reeh P. W., Handwerker H. O. Chemosensitivity of fine afferents from rat skin in vitro. J. Neurophysiol. 63:1990;887-901.
    • (1990) J. Neurophysiol. , vol.63 , pp. 887-901
    • Lang, E.1    Novak, A.2    Reeh, P.W.3    Handwerker, H.O.4
  • 23
    • 0028123430 scopus 로고
    • A rapid capsaicin-activated current in rat trigeminal ganglion neurons
    • Liu L., Simon S. A. A rapid capsaicin-activated current in rat trigeminal ganglion neurons. Proc. natn. Acad. Sci. U.S.A. 91:1994;738-741.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 738-741
    • Liu, L.1    Simon, S.A.2
  • 24
    • 0030592802 scopus 로고    scopus 로고
    • Pain from excitation of identified muscle nociceptors in humans
    • Marchettini P., Simone D. A., Caputi G., Ochoa J. L. Pain from excitation of identified muscle nociceptors in humans. Brain Res. 740:1996;109-116.
    • (1996) Brain Res. , vol.740 , pp. 109-116
    • Marchettini, P.1    Simone, D.A.2    Caputi, G.3    Ochoa, J.L.4
  • 25
    • 0023626285 scopus 로고
    • The mechanism of action of capsaicin on sensory c-type neurons and their axons in vitro
    • Marsh S. J., Stansfeld C. E., Brown D. A., Davey R., McCarthy D. The mechanism of action of capsaicin on sensory c-type neurons and their axons in vitro. Neuroscience. 23:1987;275-289.
    • (1987) Neuroscience , vol.23 , pp. 275-289
    • Marsh, S.J.1    Stansfeld, C.E.2    Brown, D.A.3    Davey, R.4    McCarthy, D.5
  • 26
    • 9244243039 scopus 로고    scopus 로고
    • Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons
    • Oh U., Hwang S. W., Kim D. Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons. J. Neurosci. 16:1996;1659-1667.
    • (1996) J. Neurosci. , vol.16 , pp. 1659-1667
    • Oh, U.1    Hwang, S.W.2    Kim, D.3
  • 27
    • 0028884581 scopus 로고
    • Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects
    • Park K. M., Max M. B., Robinovitz E., Gracely R. H., Bennet G. J. Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. Pain. 63:1995;163-172.
    • (1995) Pain , vol.63 , pp. 163-172
    • Park, K.M.1    Max, M.B.2    Robinovitz, E.3    Gracely, R.H.4    Bennet, G.J.5
  • 28
    • 0026730445 scopus 로고
    • Capsazepine reversal of the antinociceptive action of capsaicin in vivo
    • Perkins M. N., Campbell E. A. Capsazepine reversal of the antinociceptive action of capsaicin in vivo. Br. J. Pharmac. 107:1992;329-333.
    • (1992) Br. J. Pharmac. , vol.107 , pp. 329-333
    • Perkins, M.N.1    Campbell, E.A.2
  • 29
    • 0027262250 scopus 로고
    • Sensitization of peripheral afferent fibers in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins
    • Rueff A., Dray A. Sensitization of peripheral afferent fibers in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins. Neuroscience. 54:1993;527-535.
    • (1993) Neuroscience , vol.54 , pp. 527-535
    • Rueff, A.1    Dray, A.2
  • 30
    • 0027326923 scopus 로고
    • Effect of capsazepine on the release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) induced by low pH, capsaicin and potassium in rat soleus muscle
    • Santicioli P., Del Bianco E., Figini M., Bevan S., Maggi C. A. Effect of capsazepine on the release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) induced by low pH, capsaicin and potassium in rat soleus muscle. Br. J. Pharmac. 110:1993;609-612.
    • (1993) Br. J. Pharmac. , vol.110 , pp. 609-612
    • Santicioli, P.1    Del Bianco, E.2    Figini, M.3    Bevan, S.4    Maggi, C.A.5
  • 31
    • 0030590231 scopus 로고    scopus 로고
    • Topical acetylsalicylate attenuates capsaicin induced pain, flare and allodynia but not thermal hyperalgesia
    • Schmelz M., Kress M. Topical acetylsalicylate attenuates capsaicin induced pain, flare and allodynia but not thermal hyperalgesia. Neurosci. Lett. 214:1996;72-74.
    • (1996) Neurosci. Lett. , vol.214 , pp. 72-74
    • Schmelz, M.1    Kress, M.2
  • 32
    • 0024351831 scopus 로고
    • Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin
    • Simone D. A., Baumann T. K., LaMotte R. H. Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain. 38:1989;99-107.
    • (1989) Pain , vol.38 , pp. 99-107
    • Simone, D.A.1    Baumann, T.K.2    LaMotte, R.H.3
  • 33
    • 0024382437 scopus 로고
    • Resiniferitoxin, a phorbol-related diterpene acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper
    • Szallasi A., Blumberg P. M. Resiniferitoxin, a phorbol-related diterpene acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper. Neuroscience. 30:1989;515-520.
    • (1989) Neuroscience , vol.30 , pp. 515-520
    • Szallasi, A.1    Blumberg, P.M.2
  • 34
    • 0027452376 scopus 로고
    • 3H]resiniferatoxin binding to central (spinal cord and dorsal root ganglion) and peripheral (urinary bladder and airways) vanilloid (capsaicin) receptors in the rat
    • 3H]resiniferatoxin binding to central (spinal cord and dorsal root ganglion) and peripheral (urinary bladder and airways) vanilloid (capsaicin) receptors in the rat. J. Pharmac. exp. Ther. 267:1993;728-733.
    • (1993) J. Pharmac. Exp. Ther. , vol.267 , pp. 728-733
    • Szallasi, A.1    Goso, C.2    Blumberg, P.M.3    Manzini, S.4
  • 35
    • 0028868678 scopus 로고
    • Vanilloid (capsaicin) receptors in the rat: Distribution in the brain, regional differences in the spinal cord, axonal transport to the periphery, and depletion by systemic vanilloid treatment
    • Szallasi A., Nilsson S., Farkas-Szallasi T., Blumberg P. M., Hokfelt T., Lundberg J. M. Vanilloid (capsaicin) receptors in the rat: distribution in the brain, regional differences in the spinal cord, axonal transport to the periphery, and depletion by systemic vanilloid treatment. Brain Res. 703:1995;175-183.
    • (1995) Brain Res. , vol.703 , pp. 175-183
    • Szallasi, A.1    Nilsson, S.2    Farkas-Szallasi, T.3    Blumberg, P.M.4    Hokfelt, T.5    Lundberg, J.M.6
  • 36
    • 0023162373 scopus 로고
    • Selective responsiveness of polymodal nociceptors of rabbit ear to capsaicin, bradykinin and ultra-violet irradiation
    • Szolcsanyi J. Selective responsiveness of polymodal nociceptors of rabbit ear to capsaicin, bradykinin and ultra-violet irradiation. J. Physiol., Lond. 388:1987;9-23.
    • (1987) J. Physiol., Lond. , vol.388 , pp. 9-23
    • Szolcsanyi, J.1
  • 37
    • 0002919601 scopus 로고
    • Actions of capsaicin on sensory receptors
    • (ed. Wood J. N.) Academic, London
    • Szolcsanyi J. (1993) Actions of capsaicin on sensory receptors. In Capsaicin In the Study of Pain (ed. Wood J. N.), pp. 1-26. Academic, London.
    • (1993) In Capsaicin In the Study of Pain , pp. 1-26
    • Szolcsanyi, J.1
  • 38
    • 0002784280 scopus 로고    scopus 로고
    • Neurogenic inflammation: Re-evaluation of axon reflex theory
    • (eds Geppetti P. and Holzer P.) CRC, London
    • Szolcsanyi J. (1996) Neurogenic inflammation: re-evaluation of axon reflex theory. In Neurogenic Inflammation (eds Geppetti P. and Holzer P.), pp. 35-44. CRC, London.
    • (1996) In Neurogenic Inflammation , pp. 35-44
    • Szolcsanyi, J.1
  • 40
    • 0028805882 scopus 로고
    • Immune activation: The role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states
    • Watkins L. R., Maier S. F., Goehler L. E. Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states. Pain. 63:1995;289-302.
    • (1995) Pain , vol.63 , pp. 289-302
    • Watkins, L.R.1    Maier, S.F.2    Goehler, L.E.3
  • 41
    • 0025340262 scopus 로고
    • Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat
    • Williams S., Evans G. I., Hunt S. P. Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat. Neuroscience. 36:1990;73-81.
    • (1990) Neuroscience , vol.36 , pp. 73-81
    • Williams, S.1    Evans, G.I.2    Hunt, S.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.