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Volumn 56, Issue 3, 1999, Pages 581-587

The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons

Author keywords

[No Author keywords available]

Indexed keywords

VANILLOID RECEPTOR;

EID: 0032876069     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.3.581     Document Type: Article
Times cited : (125)

References (38)
  • 1
    • 16944365440 scopus 로고    scopus 로고
    • Differential activation and desensitization of sensory neurons by resiniferatoxin
    • Ács G, Bíró T, Ács P, Modarres S and Blumberg PM (1997) Differential activation and desensitization of sensory neurons by resiniferatoxin. J Neurosci 17:5622-5628.
    • (1997) J Neurosci , vol.17 , pp. 5622-5628
    • Ács, G.1    Bíró, T.2    Ács, P.3    Modarres, S.4    Blumberg, P.M.5
  • 2
    • 0030024173 scopus 로고    scopus 로고
    • 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes
    • 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes. Mol Brain Res 35:173-182.
    • (1996) Mol Brain Res , vol.35 , pp. 173-182
    • Ács, G.1    Lee, J.2    Marquez, V.E.3    Blumberg, P.M.4
  • 3
    • 0029073916 scopus 로고
    • Resiniferatoxin-amide and analogues as ligands for protein kinase C and vanilloid receptors and determination of their biological activities as vanilloids
    • Ács G, Lee J, Marquez VE, Wang S, Milne GWA, Du L, Lewin NE and Blumberg PM (1995) Resiniferatoxin-amide and analogues as ligands for protein kinase C and vanilloid receptors and determination of their biological activities as vanilloids. J Neurochem 65:301-308.
    • (1995) J Neurochem , vol.65 , pp. 301-308
    • Ács, G.1    Lee, J.2    Marquez, V.E.3    Wang, S.4    Milne, G.W.A.5    Du, L.6    Lewin, N.E.7    Blumberg, P.M.8
  • 5
    • 0025328825 scopus 로고
    • Sensory neuron-specific actions of capsaicin: Mechanisms and applications
    • Bevan S and Szolcsányi J (1990) Sensory neuron-specific actions of capsaicin: Mechanisms and applications. Trends Pharmacol Sci 11:330-333.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 330-333
    • Bevan, S.1    Szolcsányi, J.2
  • 6
    • 0030818329 scopus 로고    scopus 로고
    • Recent advances in understanding of vanilloid receptors: A therapeutic target for treatment of pain and inflammation in skin
    • Bíró T, Ács G, Ács P, Modarres S and Blumberg PM (1997) Recent advances in understanding of vanilloid receptors: A therapeutic target for treatment of pain and inflammation in skin. J Invest Dermatol Symp Proc 2:56-60.
    • (1997) J Invest Dermatol Symp Proc , vol.2 , pp. 56-60
    • Bíró, T.1    Ács, G.2    Ács, P.3    Modarres, S.4    Blumberg, P.M.5
  • 11
    • 0342437490 scopus 로고    scopus 로고
    • Suppression of bladder hyperreflexia by intravesical resiniferatoxin
    • Cruz F, Guimarães M, Silva C and Reis M (1997) Suppression of bladder hyperreflexia by intravesical resiniferatoxin. Lancet 350:640-641.
    • (1997) Lancet , vol.350 , pp. 640-641
    • Cruz, F.1    Guimarães, M.2    Silva, C.3    Reis, M.4
  • 12
    • 0025718476 scopus 로고
    • Selective antagonism of capsaicin by capsazepine: Evidence for a spinal receptor site in capsaicin-induced antinociception
    • Dickenson AH and Dray A (1991) Selective antagonism of capsaicin by capsazepine: Evidence for a spinal receptor site in capsaicin-induced antinociception. Br J Pharmacol 104:1045-1049.
    • (1991) Br J Pharmacol , vol.104 , pp. 1045-1049
    • Dickenson, A.H.1    Dray, A.2
  • 13
  • 14
    • 0025871477 scopus 로고
    • Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons
    • Holzer P (1991) Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43:144-201.
    • (1991) Pharmacol Rev , vol.43 , pp. 144-201
    • Holzer, P.1
  • 15
    • 0031786527 scopus 로고    scopus 로고
    • Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord disease
    • Lazzeri M, Spinelli M, Beneforti P, Zanollo A and Turini D (1998) Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord disease. Scand J Urol Nephrol 32:331-334.
    • (1998) Scand J Urol Nephrol , vol.32 , pp. 331-334
    • Lazzeri, M.1    Spinelli, M.2    Beneforti, P.3    Zanollo, A.4    Turini, D.5
  • 16
    • 0029880452 scopus 로고    scopus 로고
    • ++ dependence in rat trigeminal ganglion cells
    • ++ dependence in rat trigeminal ganglion cells. J Neurophysiol 75:1503-1514.
    • (1996) J Neurophysiol , vol.75 , pp. 1503-1514
    • Liu, L.1    Simon, S.2
  • 17
    • 0026468508 scopus 로고
    • Therapeutic potential of capsaicin-like molecules: Studies in animals and humans
    • Maggi CA (1992) Therapeutic potential of capsaicin-like molecules: Studies in animals and humans. Life Sci 51:1777-1781.
    • (1992) Life Sci , vol.51 , pp. 1777-1781
    • Maggi, C.A.1
  • 18
    • 0027499136 scopus 로고
    • A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens
    • Maggi CA, Bevan S, Walpole CSJ, Rang HP and Giuliani S (1993) A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens. Br J Pharmacol 108:801-805.
    • (1993) Br J Pharmacol , vol.108 , pp. 801-805
    • Maggi, C.A.1    Bevan, S.2    Walpole, C.S.J.3    Rang, H.P.4    Giuliani, S.5
  • 19
    • 0030601659 scopus 로고    scopus 로고
    • Multiple capsaicin-evoked currents in isolated rat sensory neurons
    • Petersen M, LaMotte RH, Klusch A and Kniffki KD (1996) Multiple capsaicin-evoked currents in isolated rat sensory neurons. Neuroscience 75:495-505.
    • (1996) Neuroscience , vol.75 , pp. 495-505
    • Petersen, M.1    Lamotte, R.H.2    Klusch, A.3    Kniffki, K.D.4
  • 20
    • 0028175616 scopus 로고
    • The vanilloid (capsaicin) receptor: Receptor types, species differences
    • Szallasi A (1994) The vanilloid (capsaicin) receptor: Receptor types, species differences. Gen Pharmacol 25:223-243.
    • (1994) Gen Pharmacol , vol.25 , pp. 223-243
    • Szallasi, A.1
  • 22
    • 0033001482 scopus 로고    scopus 로고
    • A non-pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors
    • Szallasi A, Bíró T, Szabó T, Modarres S, Petersen M, Klusch A, Blumberg PM, Krause JE and Sterner O (1999a) A non-pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors. Br J Pharmacol 126:1351-1358.
    • (1999) Br J Pharmacol , vol.126 , pp. 1351-1358
    • Szallasi, A.1    Bíró, T.2    Szabó, T.3    Modarres, S.4    Petersen, M.5    Klusch, A.6    Blumberg, P.M.7    Krause, J.E.8    Sterner, O.9
  • 23
    • 0024382437 scopus 로고
    • Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capssaicin, the irritant constituent in red pepper
    • Szallasi A and Blumberg PM (1989) Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capssaicin, the irritant constituent in red pepper. Neuroscience 30:515-520.
    • (1989) Neuroscience , vol.30 , pp. 515-520
    • Szallasi, A.1    Blumberg, P.M.2
  • 24
    • 0025202606 scopus 로고
    • Resiniferatoxin and analogs provide novel insights into the pharmacology of vanilloid (capsaicin) receptors
    • Szallasi A and Blumberg PM (1990a) Resiniferatoxin and analogs provide novel insights into the pharmacology of vanilloid (capsaicin) receptors. Life Sci 47:1399-1408.
    • (1990) Life Sci , vol.47 , pp. 1399-1408
    • Szallasi, A.1    Blumberg, P.M.2
  • 25
    • 0025110892 scopus 로고
    • Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes
    • Szallasi A and Blumberg PM (1990b) Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes. Brain Res 524:106-111.
    • (1990) Brain Res , vol.524 , pp. 106-111
    • Szallasi, A.1    Blumberg, P.M.2
  • 26
    • 0030443812 scopus 로고    scopus 로고
    • Vanilloid receptors: New insights enhance potential as a therapeutic target
    • Szallasi A and Blumberg PM (1996) Vanilloid receptors: New insights enhance potential as a therapeutic target. Pain 68:195-208.
    • (1996) Pain , vol.68 , pp. 195-208
    • Szallasi, A.1    Blumberg, P.M.2
  • 27
    • 0032970173 scopus 로고    scopus 로고
    • Vanilloid (capsaicin) receptors and mechanisms
    • Szallasi A and Blumberg PM (1999) Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-211.
    • (1999) Pharmacol Rev , vol.51 , pp. 159-211
    • Szallasi, A.1    Blumberg, P.M.2
  • 28
    • 0029833970 scopus 로고    scopus 로고
    • The stimulation of capsaicin-sensitive neurones in a vanilloid receptor-mediated fashion by pungent terpenoids possessing an unsaturated 1,4-dialdehyde moiety
    • Szallasi A, Jonassohn M, Ács G, Bíró T, Ács P and Blumberg PM (1996) The stimulation of capsaicin-sensitive neurones in a vanilloid receptor-mediated fashion by pungent terpenoids possessing an unsaturated 1,4-dialdehyde moiety. Br J Pharmacol 119:283-290.
    • (1996) Br J Pharmacol , vol.119 , pp. 283-290
    • Szallasi, A.1    Jonassohn, M.2    Ács, G.3    Bíró, T.4    Ács, P.5    Blumberg, P.M.6
  • 29
    • 0026795482 scopus 로고
    • 1-acid glycoprotein (orosomucoid) as a major vanilloid-binding protein in serum
    • 1-acid glycoprotein (orosomucoid) as a major vanilloid-binding protein in serum. J Pharmacol Exp Ther 262:883-888.
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 883-888
    • Szallasi, A.1    Lewin, N.E.2    Blumberg, P.M.3
  • 30
    • 0027493969 scopus 로고
    • Vanilloid (capsaicin) receptor in the rat: Positive cooperativity of resiniferatoxin binding and its modulation by reduction and oxidation
    • Szallasi A, Lewin NE and Blumberg PM (1993) Vanilloid (capsaicin) receptor in the rat: Positive cooperativity of resiniferatoxin binding and its modulation by reduction and oxidation. J Pharmacol Exp Ther 266:678-683.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 678-683
    • Szallasi, A.1    Lewin, N.E.2    Blumberg, P.M.3
  • 31
    • 0032881344 scopus 로고    scopus 로고
    • Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VRI
    • in press
    • Szallasi A, Szabó T, Bíró T, Modarres S, Blumberg PM, Krause JE, Cortright DN and Appendino G (1999b) Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VRI. Br J Pharmacol, in press.
    • (1999) Br J Pharmacol
    • Szallasi, A.1    Szabó, T.2    Bíró, T.3    Modarres, S.4    Blumberg, P.M.5    Krause, J.E.6    Cortright, D.N.7    Appendino, G.8
  • 32
    • 0025224503 scopus 로고
    • Resiniferatoxin, an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons
    • Szolcsányi J, Szallasi A, Szallasi Z, Joó F and Blumberg PM (1990) Resiniferatoxin, an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons. J Pharmacol Exp Ther 255:923-928.
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 923-928
    • Szolcsányi, J.1    Szallasi, A.2    Szallasi, Z.3    Joó, F.4    Blumberg, P.M.5
  • 35
    • 0002675324 scopus 로고
    • Structural requirements for capsaicin agonists and antagonists
    • Wood JN ed, Academic Press, San Diego
    • Walpole CSJ and Wrigglesworth R (1993) Structural requirements for capsaicin agonists and antagonists, in Capsaicin in the Study of Pain (Wood JN ed) pp 63-82, Academic Press, San Diego.
    • (1993) Capsaicin in the Study of Pain , pp. 63-82
    • Walpole, C.S.J.1    Wrigglesworth, R.2
  • 36
    • 0025296259 scopus 로고
    • Cellular mechanism of action of resiniferatoxin: A potent sensory neurotoxin
    • Winter J, Dray A, Wood JN, Yeats JC and Bevan S (1990) Cellular mechanism of action of resiniferatoxin: A potent sensory neurotoxin. Brain Res 520:131-140.
    • (1990) Brain Res , vol.520 , pp. 131-140
    • Winter, J.1    Dray, A.2    Wood, J.N.3    Yeats, J.C.4    Bevan, S.5
  • 37
    • 0027451918 scopus 로고
    • Characterization of resiniferatoxin binding sites on sensory neurons: Co-regulation of resiniferatoxin binding and capsaicin sensitivity in adult dorsal root ganglia
    • Winter J, Walpole CSJ, Bevan S and James IF (1993) Characterization of resiniferatoxin binding sites on sensory neurons: Co-regulation of resiniferatoxin binding and capsaicin sensitivity in adult dorsal root ganglia. Neuroscience 57:747-757.
    • (1993) Neuroscience , vol.57 , pp. 747-757
    • Winter, J.1    Walpole, C.S.J.2    Bevan, S.3    James, I.F.4
  • 38
    • 0023715884 scopus 로고
    • Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture
    • Wood JN, Winter J, James IF, Rang HP, Yeats J and Bevan S (1988) Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture. J Neurosci 8:3208-3220.
    • (1988) J Neurosci , vol.8 , pp. 3208-3220
    • Wood, J.N.1    Winter, J.2    James, I.F.3    Rang, H.P.4    Yeats, J.5    Bevan, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.