The principle of gating charge movement in a voltage-dependent K+ channel

Nature

Volumn 423, Issue 6935, 2003, Pages 42-48

  Jiang, Youxing ^a,b   Ruta, Vanessa ^a   Chen, Jiayun ^a   Lee, Alice ^a   MacKinnon, Roderick ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; ELECTRIC CHARGE; ELECTRIC POTENTIAL; HYDROPHOBICITY; LIPIDS; POTASSIUM;

GATING CHARGE MOVEMENT;

POSITIVE IONS;

ARGININE; AVIDIN; BIOTIN; IMMUNOGLOBULIN F(AB) FRAGMENT; TOXIN; VOLTAGE GATED POTASSIUM CHANNEL;

BIOCHEMISTRY;

ARTICLE; CHANNEL GATING; ELECTRIC FIELD; HYDROPHOBICITY; LIPID MEMBRANE; MOTION; PRIORITY JOURNAL; SENSOR;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ARCHAEAL PROTEINS; AVIDIN; BIOTIN; DESULFUROCOCCACEAE; ELECTROSTATICS; HYDROPHOBICITY; IMMUNOGLOBULIN FAB FRAGMENTS; ION CHANNEL GATING; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTION; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038752614     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01581     Document Type: Article

References (33)

1. Sigworth, F. J. Voltage gating of ion channels. Q. Rev. Biophys. 27, 1-40 (1994).
2. + channels. J. Gen. Physiol. 63, 533-552 (1974).
3. Bezanilla, F. The voltage sensor in voltage-dependent ion channels. Physiol. Rev. 80, 555-592 (2000).
4. + channel. Nature 423, 33-41 (2003).
5. + channel. Nature 422,180-185; advance online publication, 2 March 2003 (doi:10.1038/nature01473).
6. + channels. Neuron 18, 675-682 (1997).
7. Slatin, S. L., Qiu, X. Q., Jakes, K. S. & Finkelstein, A. Identification of a translocated protein segment in a voltage-dependent channel. Nature 371, 158-161 (1994).
8. Qiu, X. Q., Jakes, K. S., Finkelstein, A. & Slatin, S. L. Site-specific biotinylation of colicin Ia. A probe for protein conformation in the membrane. J. Biol. Chem. 269, 7483-7488 (1994).
9. Qiu, X. Q., Jakes, K. S., Kienker, P. K., Finkelstein, A. & Statin, S. L. Major transmembrane movement associated with colicin Ia channel gating. J. Gen. Physiol. 107, 313-328 (1996).
10. Pugliese, L., Coda, A., Malcovati, M. & Bolognesi, M. Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 Å resolution. J. Mol. Biol. 231, 698-710 (1993).
11. Zagotta, W. N., Hoshi, T., Dittman, J. & Aldrich, R. W. Shaker potassium channel gating. II. Transitions in the activation pathway. J. Gen. Physiol. 103, 279-319 (1994).
12. Zagotta, W. N., Hoshi, T. & Aldrich, R. W. Shaker potassium channel gating. III. Evaluation of kinetic models for activation. J. Gen. Physiol. 103, 321-362 (1994).
13. Schoppa, N. E. & Sigworth, F. J. Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J. Gen. Physiol. 111, 313-342 (1998).
14. Cole, K. S. & Moore, J. W. Potassium ion current in the squid giant axon: dynamic characteristic. Biophys. J. 1, 1-14 (1960).
15. Schoppa, N. E., McCormack, K., Tanouye, M. A. & Sigworth, F. J. The size of gating charge in wild-type and mutant Shaker potassium channels. Science 255, 1712-1715 (1992).
16. + channel. Neuron 16, 1159-1167 (1996).
17. + channel. Neuron 16, 1169-1177 (1996).
18. + channel. Neuron 14, 1293-1301 (1995).
19. + channel. J. Gen. Physiol. 115, 123-138 (2000).
20. Papazian, D. M., Silverman, W. R., Lin, M. C., Tiwari-Woodruff, S. K. & Tang, C. Y. Structural organization of the voltage sensor in voltage-dependent potassium channels. Novartis Found. Symp. 245, 178-190 (2002).
21. + channel gating kinetics by deletions in the S3-S4 linker. Proc. Natl Acad. Sci. USA 98, 9617-9623 (2001).
22. Wimley, W. C., Creamer, T. P. & White, S. H. Solvation energies of amino acid side chains and backbone in a family of host-guest pentapeptides. Biochemistry 35, 5109-5124 (1996).
23. Bass, R. B., Strop, P., Barclay, M. & Rees, D. C. Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel. Science 298, 1582-1587 (2002).
24. Martinac, B., Buechner, M., Delcour, A. H., Adler, J. & Kung, C. Pressure-sensitive ion channel in Escherichia coli. Proc. Natl Acad. Sci. USA 84, 2297-2301 (1987).
25. + conduction and selectivity. Science 280, 69-77 (1998).
26. Jiang, Y. et al. The open pore conformation of potassium channels. Nature 417, 523-526 (2002).
27. + channel. Cell 111, 231-239 (2002).
28. + channels. Biophys. J. 82, 231a (2002).
29. Aziz, Q. H., Partridge, C. J., Munsey, T. S. & Sivaprasadarao, A. Depolarization induces intersubunit cross-linking in a S4 cysteine mutant of the Shaker potassium channel. J. Biol. Chem. 277, 42719-42725 (2002).
30. Larsson, H. P., Baker, O. S., Dhillon, D. S. & Isacoff, E. Y. Transmembrane movement of the Shaker K+ channel S4. Neuron 16, 387-397 (1996).
31. Yusaf, S. P., Wray, D. & Sivaprasadarao, A. Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel. Pflugers Arch. 433, 91-97 (1996).
32. + channel gating. Neuron 20, 1283-1294 (1998).
33. + channel. Neuron 19, 1319-1327 (1997).