4-(2-Pyridyl)piperazine-1-carboxamides: Potent vanilloid receptor 1 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 20, 2003, Pages 3611-3616

  Sun, Qun ^a   Tafesse, Laykea ^a   Islam, Khondaker ^a   Zhou, Xiaoming ^a   Victory, Sam F ^a   Zhang, Chongwu ^a   Hachicha, Mohamed ^a   Schmid, Lori A ^a   Patel, Aniket ^a   Rotshteyn, Yakov ^a   Valenzano, Kenneth J ^a   Kyle, Donald J ^a  

^a PURDUE PHARMA L P   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CAPSAICIN; PIPERAZINE DERIVATIVE; VANILLOID RECEPTOR;

ARTICLE; CELL LINE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PH; PROTEIN EXPRESSION; RAT; STRUCTURE ACTIVITY RELATION;

EID: 10744226592     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00759-5     Document Type: Article

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16. NMR data for compounds 2-31. See Abstract.
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