Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels

British Journal of Pharmacology

Volumn 143, Issue 2, 2004, Pages 251-256

  De Petrocellis, Luciano ^a   Chu, Constance J ^b   Schiano Moriello, Aniello ^a   Kellner, Juliane C ^b   Walker, J Michael ^b   Di Marzo, Vincenzo ^a  

^a CNR   (Italy)

^b BROWN UNIVERSITY   (United States)

Author keywords

Anandamide; Calcium; Cannabinoid; Channel; Endocannabinoid; Hyperalgesia; Inflammation; Pain; Receptor; VR1

Indexed keywords

ANANDAMIDE; CALCIUM; CAPSAICIN; CARRAGEENAN; DOPAMINE DERIVATIVE; LIPID; N ARACHIDONOYLDOPAMINE; N OLEOYLDOPAMINE; N PALMITOYLDOPAMINE; N STEAROYLDOPAMINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CATTLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; DRUG RECEPTOR BINDING; EMBRYO; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LATENT PERIOD; MALE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PH; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION;

ANIMALS; ARACHIDONIC ACIDS; CALCIUM; CARRAGEENAN; CELL LINE; DISEASE MODELS, ANIMAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HINDLIMB; HUMANS; HYPERALGESIA; INFLAMMATION; ITALY; KIDNEY; MALE; PAIN MEASUREMENT; PALMITATES; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG; STEARATES; TRPV CATION CHANNELS;

EID: 4744350135     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705924     Document Type: Article

References (22)

1. AHERN, G.P. (2003). Activation of TRPV1 by the satiety factor oleoylethanolamide. J. Biol. Chem., 278, 30429-30434.
2. BISOGNO, T., MELCK, D., BOBROV, M.YU., GRETSKAYA, N.M., BEZUGLOV, V.V., DE PETROCELLIS, L. & DI MARZO, V. (2000). N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. Biochem. J., 351, 817-824.
3. CATERINA, M.J. (2003). Vanilloid receptors take a TRP beyond the sensory afferent. Pain, 105, 5-9.
4. CATERINA, M.J., SCHUMACHER, M.A., TOMINAGA, M., ROSEN, T.A., LEVINE, J.D. & JULIUS, D. (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 389, 816-824.
5. CHU, C.J., HUANG, S.M., DE PETROCELLIS, L., BISOGNO, T., EWING, S.A., MILLER, J.D., ZIPKIN, R.E., DADDARIO, N., APPENDINO, G., DI MARZO, V. & WALKER, J.M. (2003). N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J. Biol. Chem., 278, 13633-13639.
6. CHUANG, H.H., PRESCOTT, E.D., KONG, H., SHIELDS, S., JORDT, S.E., BASBAUM, A.I., CHAO, M.V. & JULIUS, D. (2001). Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature, 411, 957-962.
7. DAVIS, J.B., GRAY, J., GUNTHORPE, M.J., HATCHER, J.P., DAVEY, P.T., OVEREND, P., HARRIES, M.H., LATCHAM, J., CLAPHAM, C., ATKINSON, K., HUGHES, S.A., RANCE, K., GRAU, E., HARPER, A.J., PUGH, P.L., ROGERS, D.C., BINGHAM, S., RANDALL, A. & SHEARDOWN, S.A. (2000). Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature, 405, 183-187.
8. DE PETROCELLIS, L., DAVIS, J.B. & DI MARZO, V. (2001). Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. FEBS Lett., 506, 253-256.
9. DEVANE, W.A., HANUS, L., BREUER, A., PERTWEE, R.G., STEVENSON, L.A., GRIFFIN, G., GIBSON, D., MANDELBAUM, A., ETINGER, A. & MECHOULAM, R. (1992). Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science, 258, 1946-1949.
10. DI MARZO, V., BLUMBERG, P.M. & SZALLASI, A. (2002). Endovanilloid signaling in pain. Curr. Opin. Neurobiol., 12, 372-379.
11. FU, J., GAETANI, S., OVEISI, F., LO VERME, J., SERRANO, A., RODRIGUEZ DE FONSECA, F., ROSENGARTH, A., LUECKE, H., DI GIACOMO, B., TARZIA, G. & PIOMELLI, D. (2003). Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature, 425, 90-93.
12. HUANG, S.M., BISOGNO, T., TREVISANI, M., AL-HAYANI, A., DE PETROCELLIS, L., FEZZA F TOGNETTO, M., PETROS, T.J., KREY, J.F., CHU, C.J., MILLER, J.D., DAVIES, S.N., GEPPETTI, P., WALKER, J.M. & DI MARZO, V. (2002). An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc. Natl. Acad. Sci. U.S.A., 99, 8400-8405.
13. HWANG, S.W., CHO, H., KWAK, J., LEE, S.Y., KANG, C.J., JUNG, J., CHO, S., MIN, K.H., SUH, Y.G., KIM, D. & OH, U. (2000). Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc. Natl. Acad. Sci. U.S.A., 97, 6155-6160.
14. LAMBERT, D.M. & DI MARZO, V. (1999). The palmitoylethanolamide and oleamide enigmas: are these two fatty acid amides cannabimimetic? Curr. Med. Chem., 6, 757-773.
15. MACCARRONE, M., CARTONI, A., PAROLARO, D., MARGONELLI, A., MASSI, P., BARI, M., BATTISTA, N. & FINAZZI-AGRO', A. (2002a). Cannabimimetic activity, binding, and degradation of stearoylethanolamide within the mouse central nervous system. Mol. Cell Neurosci., 21, 126-140.
16. MACCARRONE, M., PAUSELLI, R., DI RIENZO, M. & FINAZZI-AGRO', A. (2002b). Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem. J., 366, 137-144.
17. SMART, D., GUNTHORPE, M.J., JERMAN, J.C., NASIR, S., GRAY, J., MUIR, A.I., CHAMBERS, J.K., RANDALL, A.D. & DAVIS, J.B. (2000). The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). Br. J. Pharmacol., 129, 227-230.
18. SMART, D., JONSSON, K.O., VANDEVOORDE, S., LAMBERT, D.M. & FOWLER, C.J. (2002). 'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism. Br. J. Pharmacol., 136, 452-458.
19. SZALLASI, A. & BLUMBERG, P.M. (1999). Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol. Rev., 51, 159-212.
20. TOMINAGA, M., CATERINA, M.J., MALMBERG, A.B., ROSEN, T.A., GILBERT, H., SKINNER, K., RAUMANN, B.E., BASBAUM, A.I. & JULIUS, D. (1998). The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron, 21, 531-543.
21. WATANABE, H., VRIENS, J., PRENEN, J., DROOGMANS, G., VOETS, T. & NILIUS, B. (2003). Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature, 424, 434-438.
22. ZYGMUNT, P.M., PETERSSON, J., ANDERSSON, D.A., CHUANG, H., SORGARD, M., DI MARZO, V., JULIUS, D. & HOGESTATT, E.D. (1999). Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature, 400, 452-457.