Nuclear factor kappa B is a promising therapeutic target in inflammatory lung disease

Current Drug Targets

Volumn 7, Issue 6, 2006, Pages 661-668

  Park, Gye Young ^a   Christman, John W ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Inhibitory kappa B kinases (IKK); Neutrophils; Phosphorylation; Posttranslational modification; Proinflammatory mediators

Indexed keywords

ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ASCORBIC ACID; BMS 34554; BMS 345541; BORTEZOMIB; COMPLEMENTARY RNA; CYCLOPENTENONE DERIVATIVE; DNA; ENZYME INHIBITOR; GENE PRODUCT; I KAPPA B; I KAPPA B KINASE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTAGLANDIN DERIVATIVE; PROTEASOME; SALICYLATE SODIUM; SC 514; SILIBININ; SMALL INTERFERING RNA; THALIDOMIDE; TRANSCRIPTION FACTOR RELA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ACETYLATION; CELL TYPE; CLINICAL TRIAL; DRUG BIOAVAILABILITY; DRUG HALF LIFE; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENE TECHNOLOGY; HEMATOLOGIC MALIGNANCY; HUMAN; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; MOLECULAR BIOLOGY; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PNEUMONIA; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; SOLID TUMOR; TRANSCRIPTION REGULATION; UBIQUITINATION;

ANIMALS; ENZYME INHIBITORS; HUMANS; I-KAPPA B KINASE; LUNG; MACROPHAGES, ALVEOLAR; NEUTROPHIL INFILTRATION; NF-KAPPA B; PNEUMONIA; SIGNAL TRANSDUCTION;

EID: 33744825413     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945006777435317     Document Type: Review

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