Stimulation of CREB binding protein nucleosomal histone acetyltransferase activity by a class of transcriptional activators

Molecular and Cellular Biology

Volumn 21, Issue 2, 2001, Pages 476-487

  Chen, C J ^a   Deng, Z ^a   Kim, A Y ^a   Blobel, G A ^a   Lieberman, P M ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE ACETYLTRANSFERASE; IMMEDIATE EARLY PROTEIN BZLF1; LEUCINE ZIPPER PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2; TRANSCRIPTION FACTOR PIT 1; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ACETYLATION; ARTICLE; CONTROLLED STUDY; DNA HISTONE INTERACTION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; TRANSCRIPTION REGULATION;

ACETYLATION; ACETYLTRANSFERASES; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL LINE; CREB-BINDING PROTEIN; DNA; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; G-BOX BINDING FACTORS; GATA1 TRANSCRIPTION FACTOR; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; NF-E2 TRANSCRIPTION FACTOR; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; NUCLEAR PROTEINS; NUCLEOSOMES; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; VIRAL PROTEINS;

EID: 0035159191     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.2.476-487.2001     Document Type: Article

References (73)

1. The Epstein-Barr virus BZLF1 protein interacts physically and functionally with the histone acetylase CREB-binding protein
2. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A
3. Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis
4. The NF-E2 transcription factor
5. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
6. NF-E2 disrupts chromatin structure at human β-globin locus control region hypersensitive site 2 in vivo
7. The CBP co-activator is a histone acetyltransferase
8. Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro
9. Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex
10. Transcription factor access to chromatin
11. Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression
12. CREB-binding protein and p300: Molecular integrators of hematopoietic transcription
13. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation
14. Regulation of activity of the transcription factor GATA-1 by acetylation
15. Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
16. Identification of cellular target genes of the Epstein-Barr virus transactivator Zta: Activation of transforming growth factor βigh3 (TGF-βigh3) and TGF-β1
17. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity
18. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
19. The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2
20. Assembly of the isomerized TFIIA-TFIID-TATA ternary complex is necessary and sufficient for gene activation
21. Phosphorylated CREB binds specifically to the nuclear protein CBP
22. Analysis of transcription factor binding to nucleosomes
23. Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA
24. CBP as a transcriptional coactivator of c-Myb
25. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
26. The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription coactivator family, including the CREB-binding protein CBP and p300
27. Chromatin structure of Esptein-Barr virus
28. Association of p300 and CBP with simian virus 40 large T antigen
29. Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos
30. Replication of Epstein-Barr virus oriLyt: Lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays
31. DNA-binding-defective mutants of the Epstein-Barr virus lyric switch activator Zta transactivate with altered specificities
32. Alteration of a single serine in the basic domain of Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency
33. Conjunction dysfunction: CBP/p300 in human disease
34. The multifunctional role of the co-activator CBP in transcriptional regulation
35. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: Characterization of an Ada complex and the SAGA (Spt/Ada) complex
36. Histone acetylation in chromatin structure and transcription
37. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
38. Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein Twist and adenoviral oncoprotein E1A
39. mof, a putative acetyltransferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila
40. Histone acetyltransferase complexes and their link to transcription
41. CREB-binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites
42. Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation
43. Modifying chromatin and concepts of cancer
44. Histone acetylation and reactivation of Epstein-Barr virus from latency
45. Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines
46. Epstein-Barr virus and its replication
47. Biological role of the CCAAT/Enhancer-binding protein family of transcription factors
48. Locus control regions: Coming of age at a decade plus
49. p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption
50. A mechanism for TAFs in transcriptional activation: Activation domain enhancement of TFIID-TFIIA-promoter DNA complex formation
51. Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regions
52. The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions
53. Requirement for TFIIA-TFIID recruitment by an activator depends on promoter structure and template competition
54. Binding and modulation of p53 by p300/CBP coactivators
55. Crystal structure of the nucleosome core particle at 2.8 A resolution
56. The histone tails of the nucleosome
57. The acetyltransferase activity of CBP stimulates transcription
58. Recruitment of CBP/p300 by the IFNb enhanceosome is required for synergistic activation of transcription
59. The TAFII250 subunit of TFIID has histone acetyltransferase activity
60. Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome
61. The transcriptional coactivators p300 and CBP are histone acetyltransferases
62. Epstein-Barr virus
63. CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein
64. The p300/CBP family: Integration signals with transcription factors and chromatin
65. Steroid receptor coactivator-1 is a histone acetyltransferase
66. The language of covalent histone modifications
67. Histone acetylation and transcriptional regulatory mechanisms
68. Co-activators and co-repressors in the integration of transcriptional responses
69. Transcription activators direct histone acetyltransferase complexes to nucleosomes
70. Histone acetyltransferases in control
71. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
72. The amino-terminal C/H1 domain of CREB binding protein mediates Zta transcription activation of latent Epstein-Barr virus
73. Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases