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Volumn 300, Issue 4, 2003, Pages 807-812

Phosphorylation of serine 276 is essential for p65 NF-κB subunit-dependent cellular responses

Author keywords

Cell death; NF B; p65; Phosphorylation; TNF; Transcriptional activity

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; P65 PROTEIN; PROTEIN DERIVATIVE; PROTEIN SUBUNIT; SERINE 276; SERINE DERIVATIVE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 0037462880     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02932-7     Document Type: Article
Times cited : (143)

References (24)
  • 2
    • 0031897632 scopus 로고    scopus 로고
    • NF- κB and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S., May M.J., Kopp E.B. NF-. κB and Rel proteins: evolutionarily conserved mediators of immune responses Annu. Rev. Immunol. 16:1998;225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 3
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF- κB activity
    • Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-. κB activity Annu. Rev. Immunol. 18:2000;621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 5
    • 0033485542 scopus 로고    scopus 로고
    • NF- κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
    • Pomerantz J.L., Baltimore D. NF-. κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase EMBO J. 18:1999;6694-6704.
    • (1999) EMBO J. , vol.18 , pp. 6694-6704
    • Pomerantz, J.L.1    Baltimore, D.2
  • 6
    • 0033623848 scopus 로고    scopus 로고
    • IKK ε is part of a novel PMA-inducible IκB kinase complex
    • Peters R.T., Liao S.M., Maniatis T. IKK. ε is part of a novel PMA-inducible IκB kinase complex Mol. Cell. 5:2000;513-522.
    • (2000) Mol. Cell , vol.5 , pp. 513-522
    • Peters, R.T.1    Liao, S.M.2    Maniatis, T.3
  • 9
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF- κB puzzle
    • Ghosh S., Karin M. Missing pieces in the NF-. κB puzzle Cell. 109(Suppl):2002;S81-S96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 10
    • 0030991201 scopus 로고    scopus 로고
    • The transcriptional activity of NF- κB is regulated by the IκB -associated PKAc subunit through a cyclic AMP-independent mechanism
    • Zhong H., SuYang H., Erdjument-Bromage H., Tempst P., Ghosh S. The transcriptional activity of NF-. κB is regulated by the IκB -associated PKAc subunit through a cyclic AMP-independent mechanism Cell. 89:1997;413-424.
    • (1997) Cell , vol.89 , pp. 413-424
    • Zhong, H.1    SuYang, H.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 11
    • 0030911732 scopus 로고    scopus 로고
    • Activation of transcription factor NF- κB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
    • Wesselborg S., Bauer M.K., Vogt M., Schmitz M.L., Schulze-Osthoff K. Activation of transcription factor NF-. κB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways J. Biol. Chem. 272:1997;12422-12429.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12422-12429
    • Wesselborg, S.1    Bauer, M.K.2    Vogt, M.3    Schmitz, M.L.4    Schulze-Osthoff, K.5
  • 12
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF- κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
    • Madrid L.V., Mayo M.W., Reuther J.Y., Baldwin A.S. Jr. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-. κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38 J. Biol. Chem. 276:2001;18934-18940.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin A.S., Jr.4
  • 13
    • 0033038491 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF- κB p65/RelA subunit
    • Sizemore N., Leung S., Stark G.R. Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-. κB p65/RelA subunit Mol. Cell. Biol. 19:1999;4798-4805.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4798-4805
    • Sizemore, N.1    Leung, S.2    Stark, G.R.3
  • 14
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF- κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong H., Voll R.E., Ghosh S. Phosphorylation of NF-. κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300 Mol. Cell. 1:1998;661-671.
    • (1998) Mol. Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 15
    • 0032589462 scopus 로고    scopus 로고
    • IκB kinases phosphorylate NF- κB p65 subunit on serine 536 in the transactivation domain
    • Sakurai H., Chiba H., Miyoshi H., Sugita T., Toriumi W. IκB kinases phosphorylate NF- κB p65 subunit on serine 536 in the transactivation domain J. Biol. Chem. 274:1999;30353-30356.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 16
    • 0034693133 scopus 로고    scopus 로고
    • Tumor necrosis factor α -induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
    • Wang D., Westerheide S.D., Hanson J.L., Baldwin A.S. Jr. Tumor necrosis factor. α -induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II J. Biol. Chem. 275:2000;32592-32597.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32592-32597
    • Wang, D.1    Westerheide, S.D.2    Hanson, J.L.3    Baldwin A.S., Jr.4
  • 17
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase- 3β in cell survival and NF- κB activation
    • Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., Woodgett J.R. Requirement for glycogen synthase kinase-. 3β in cell survival and NF- κB activation Nature. 406:2000;86-90.
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 18
    • 0030999057 scopus 로고    scopus 로고
    • NF- κB RelA-deficient lymphocytes: Normal development of T cells and B cells impaired production of IgA and IgG1 and reduced proliferative responses
    • Doi T.S., Takahashi T., Taguchi O., Azuma T., Obata Y. NF-. κB RelA-deficient lymphocytes: normal development of T cells and B cells impaired production of IgA and IgG1 and reduced proliferative responses J. Exp. Med. 185:1997;953-961.
    • (1997) J. Exp. Med. , vol.185 , pp. 953-961
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3    Azuma, T.4    Obata, Y.5
  • 20
    • 15444346943 scopus 로고    scopus 로고
    • CD27, a member of the tumor necrosis factor receptor superfamily, activates NF- κB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF- κB -inducing kinase
    • Akiba H., Nakano H., Nishinaka S., Shindo M., Kobata T., Atsuta M., Morimoto C., Ware C.F., Malinin N.L., Wallach D., Yagita H., Okumura K. CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-. κB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF- κB -inducing kinase J. Biol. Chem. 273:1998;13353-13358.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13353-13358
    • Akiba, H.1    Nakano, H.2    Nishinaka, S.3    Shindo, M.4    Kobata, T.5    Atsuta, M.6    Morimoto, C.7    Ware, C.F.8    Malinin, N.L.9    Wallach, D.10    Yagita, H.11    Okumura, K.12
  • 23
    • 0032583949 scopus 로고    scopus 로고
    • Differential regulation of IκB kinase α and β by two upstream kinases, NF- κB -inducing kinase and mitogen-activated protein kinase/ERK kinase-1
    • Nakano H., Shindo M., Sakon S., Nishinaka S., Mihara M., Yagita H., Okumura K. Differential regulation of. IκB kinase α and β by two upstream kinases, NF- κB -inducing kinase and mitogen-activated protein kinase/ERK kinase-1 Proc. Natl. Acad. Sci. USA. 95:1998;3537-3542.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3537-3542
    • Nakano, H.1    Shindo, M.2    Sakon, S.3    Nishinaka, S.4    Mihara, M.5    Yagita, H.6    Okumura, K.7
  • 24
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF- κB in preventing TNF- α -induced cell death
    • Beg A.A., Baltimore D. An essential role for NF-. κB in preventing TNF- α -induced cell death Science. 274:1996;782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.