메뉴 건너뛰기




Volumn 171, Issue 4, 2003, Pages 1750-1757

RNA interference shows critical requirement for NF-κB p50 in the production of IL-12 by human dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; GAMMA INTERFERON; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; PROTEIN P40; PROTEIN P50; RNA; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

EID: 0041622790     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.4.1750     Document Type: Article
Times cited : (76)

References (39)
  • 1
    • 0035838981 scopus 로고    scopus 로고
    • Regulation of T cell immunity by dendritic cells
    • Lanzavecchia, A., and F. Sallusto. 2001. Regulation of T cell immunity by dendritic cells. Cell 106:263.
    • (2001) Cell , vol.106 , pp. 263
    • Lanzavecchia, A.1    Sallusto, F.2
  • 2
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • Mellman, I., and R. M. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106:255.
    • (2001) Cell , vol.106 , pp. 255
    • Mellman, I.1    Steinman, R.M.2
  • 3
    • 0035883151 scopus 로고    scopus 로고
    • NF-κB signaling pathways in mammalian and insect innate immunity
    • Silverman, N., and T. Maniatis. 2001. NF-κB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15:2321.
    • (2001) Genes Dev. , vol.15 , pp. 2321
    • Silverman, N.1    Maniatis, T.2
  • 4
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-KB puzzle
    • Ghosh, S., and M. Karin. 2002. Missing pieces in the NF-KB puzzle. Cell 109:S81.
    • (2002) Cell , vol.109
    • Ghosh, S.1    Karin, M.2
  • 6
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Kontgen, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1965.
    • (1995) Genes Dev. , vol.9 , pp. 1965
    • Kontgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 7
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
    • Sha, W. C., H. C. Liou, E. I. Tuomanen, and D. Baltimore. 1995. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80:321.
    • (1995) Cell , vol.80 , pp. 321
    • Sha, W.C.1    Liou, H.C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 10
    • 0036199656 scopus 로고    scopus 로고
    • Dendritic cell development and survival require distinct NF-κB subunits
    • Ouaaz, F., J. Arron, Y. Zheng, Y. Choi, and A. Beg. 2002. Dendritic cell development and survival require distinct NF-κB subunits. Immunity 16:257.
    • (2002) Immunity , vol.16 , pp. 257
    • Ouaaz, F.1    Arron, J.2    Zheng, Y.3    Choi, Y.4    Beg, A.5
  • 12
    • 0033976062 scopus 로고    scopus 로고
    • Differential expression of Rel/NF-κB and octamer factors is a hallmark of the generation and maturation of dendritic cells
    • Neumann, M., H. Fries, C. Scheicher, P. Keikavoussi, A. Kolb-Maurer, E. Brocker, E. Serfling, and E. Kampgen. 2000. Differential expression of Rel/NF-κB and octamer factors is a hallmark of the generation and maturation of dendritic cells. Blood 95:277.
    • (2000) Blood , vol.95 , pp. 277
    • Neumann, M.1    Fries, H.2    Scheicher, C.3    Keikavoussi, P.4    Kolb-Maurer, A.5    Brocker, E.6    Serfling, E.7    Kampgen, E.8
  • 13
    • 0034743546 scopus 로고    scopus 로고
    • Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
    • Yoshimura, S., J. Bondeson, F. M. Brennan, B. M. Foxwell, and M. Feldmann. 2001. Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. Eur. J. Immunol. 31:1883.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1883
    • Yoshimura, S.1    Bondeson, J.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5
  • 14
    • 0035022325 scopus 로고    scopus 로고
    • Effective antigen presentation by dendritic cells is NF-κB dependent: Coordinate regulation of MHC, costimulatory molecules and cytokines
    • Yoshimura, S., J. Bondeson, B. M. Foxwell, F. M. Brennan, and M. Feldmann. 2001. Effective antigen presentation by dendritic cells is NF-κB dependent: coordinate regulation of MHC, costimulatory molecules and cytokines. Int. Immunol. 13:675.
    • (2001) Int. Immunol. , vol.13 , pp. 675
    • Yoshimura, S.1    Bondeson, J.2    Foxwell, B.M.3    Brennan, F.M.4    Feldmann, M.5
  • 15
    • 0036604277 scopus 로고    scopus 로고
    • CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-κB
    • O'Sullivan, B. J., and R. Thomas. 2002. CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-κB. J. Immunol. 168:5491.
    • (2002) J. Immunol. , vol.168 , pp. 5491
    • O'Sullivan, B.J.1    Thomas, R.2
  • 16
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G. J. 2002. RNA interference. Nature 418:244.
    • (2002) Nature , vol.418 , pp. 244
    • Hannon, G.J.1
  • 17
    • 0036245743 scopus 로고    scopus 로고
    • Expanding small RNA interference
    • Tuschl, T. 2002. Expanding small RNA interference. Nat. Biotechnol. 20:446.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 446
    • Tuschl, T.1
  • 18
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus, M. T., and P. A. Sharp. 2002. Gene silencing in mammals by small interfering RNAs, Nat. Rev. Genet. 3:737.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 737
    • McManus, M.T.1    Sharp, P.A.2
  • 19
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494.
    • (2001) Nature , vol.411 , pp. 494
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 20
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth, J., S. M. Elbashir, K. Bechert, T. Tuschl, and K. Weber, 2001. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114:4557.
    • (2001) J. Cell Sci. , vol.114 , pp. 4557
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuschl, T.4    Weber, K.5
  • 21
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • Caplen, N. J., S. Parrish. F. Imani, A. Fire, and R. A. Morgan. 2001. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA 98:9742.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9742
    • Caplen, N.J.1    Parrish, S.2    Imani, F.3    Fire, A.4    Morgan, R.A.5
  • 22
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir, S. M., J. Harborth, K. Weber, and T. Tuschl. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26:199.
    • (2002) Methods , vol.26 , pp. 199
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 23
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque, J. M., K. Triques, and M. Stevenson. 2002. Modulation of HIV-1 replication by RNA interference. Nature 418:435.
    • (2002) Nature , vol.418 , pp. 435
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 24
    • 0037063364 scopus 로고    scopus 로고
    • Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)
    • Heinonen, J. E., C. L. Smith, and B. F. Nore. 2002. Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA). FEBS Lett. 527:274.
    • (2002) FEBS Lett. , vol.527 , pp. 274
    • Heinonen, J.E.1    Smith, C.L.2    Nore, B.F.3
  • 27
    • 0033230617 scopus 로고    scopus 로고
    • PKR; a sentinel kinase for cellular stress
    • Williams, B. R. 1999. PKR; a sentinel kinase for cellular stress. Oncogene 18:6112.
    • (1999) Oncogene , vol.18 , pp. 6112
    • Williams, B.R.1
  • 28
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens
    • Kadowaki. N., S. Ho, S. Antonenko, R. W. Malefyt, R. A. Kastelein, F. Bazan, and Y. J. Liu. 2001. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194:863.
    • (2001) J. Exp. Med. , vol.194 , pp. 863
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.J.7
  • 29
    • 2542434337 scopus 로고    scopus 로고
    • Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand
    • Wesa, A., and A. Galy. 2002. Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand. BMC Immunol. 3:14.
    • (2002) BMC Immunol. , vol.3 , pp. 14
    • Wesa, A.1    Galy, A.2
  • 31
    • 0033490502 scopus 로고    scopus 로고
    • Interleukin-12: A cytokine at the interface of inflammation and immunity
    • Trinchieri, G. 1998. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv. Immunol. 70:83.
    • (1998) Adv. Immunol. , vol.70 , pp. 83
    • Trinchieri, G.1
  • 32
    • 0034872151 scopus 로고    scopus 로고
    • IL-1β regulates the production of IL-12 by monocyte-derived dendritic cells
    • Wesa, A., and A. Galy. 2001. IL-1β regulates the production of IL-12 by monocyte-derived dendritic cells. Int. Immunol. 13:1053.
    • (2001) Int. Immunol. , vol.13 , pp. 1053
    • Wesa, A.1    Galy, A.2
  • 33
    • 0032513227 scopus 로고    scopus 로고
    • Synergistic regulation of the human interleukin-12 p40 promoter by NFκB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages
    • Gri, G., D. Savio, G. Trinchieri, and X. Ma. 1998. Synergistic regulation of the human interleukin-12 p40 promoter by NFκB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages. J. Biol. Chem. 273: 6431.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6431
    • Gri, G.1    Savio, D.2    Trinchieri, G.3    Ma, X.4
  • 34
    • 0345346375 scopus 로고    scopus 로고
    • Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and to bacterial IL-12 inducers: Decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells
    • Kalinski, P., J. H. Schuitemaker, C. M. Hilkens, E. A. Wierenga. and M. L. Kapsenberg. 1999. Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells. J. Immunol. 162:3231.
    • (1999) J. Immunol. , vol.162 , pp. 3231
    • Kalinski, P.1    Schuitemaker, J.H.2    Hilkens, C.M.3    Wierenga, E.A.4    Kapsenberg, M.L.5
  • 35
    • 0034305809 scopus 로고    scopus 로고
    • Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cells
    • Langenkamp, A., M. Messi, A. Lanzavecchia, and F. Sallusto. 2000. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat. Immunol. 1:311.
    • (2000) Nat. Immunol. , vol.1 , pp. 311
    • Langenkamp, A.1    Messi, M.2    Lanzavecchia, A.3    Sallusto, F.4
  • 37
    • 0033198141 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in NF-κB-deficient mice: Roles of NF-κB in the activation and differentiation of autoreactive T cells
    • Hilliard, B., E. B. Samoilova, T. S. Liu, A. Rostami, and Y. Chen. 1999. Experimental autoimmune encephalomyelitis in NF-κB-deficient mice: roles of NF-κB in the activation and differentiation of autoreactive T cells. J. Immunol. 163:2937.
    • (1999) J. Immunol. , vol.163 , pp. 2937
    • Hilliard, B.1    Samoilova, E.B.2    Liu, T.S.3    Rostami, A.4    Chen, Y.5
  • 38
    • 0034633631 scopus 로고    scopus 로고
    • RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function
    • O'Sullivan, B. J., K. P. MacDonald, A. R. Pettit, and R. Thomas. 2000. RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. Proc. Natl. Acad. Sci. USA 97:11421.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11421
    • O'Sullivan, B.J.1    MacDonald, K.P.2    Pettit, A.R.3    Thomas, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.