Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 6 23-6, 2000, Pages

  Abraham, Edward ^a,b   Carmody, Aaron ^a   Shenkar, Robert ^a   Arcaroli, John ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Cytokines; Interleukin 1 ; Macrophage inflammatory protein 2; Nuclear factor B; Tumor necrosis factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EFFECTOR CELL; ENDOTOXEMIA; ENZYME ACTIVATION; IMMUNE RESPONSE; LUNG EDEMA; LUNG HEMORRHAGE; LUNG INJURY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0034536222     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.6.l1137     Document Type: Article

References (33)

1. Contribution of tumor necrosis factor α to pulmonary cytokine expression and lung injury following hemorrhage and resuscitation
2. Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation
3. NF-κB: Ten years after
4. Function and activation of NF-κB in the immune system
5. The American-European consensus conference on ARDS: Definitions, mechanisms, relevant outcomes, and clinical trial coordination
6. In vivo antioxidant treatment suppresses nuclear factor-κB activation and neutrophilic lung inflammation
7. The production of cytokines by polymorphonuclear neutrophils
8. Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS
9. A mouse model of lung injury induced by microbial products: Implication of tumor necrosis factor
10. The role of P-selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice
11. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups
12. Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
13. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome
14. Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia
15. Clinical risks for development of the acute respiratory distress syndrome
16. P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver
17. Corticotropin-releasing factor reduces lipopolysaccharide-induced pulmonary vascular leak
18. The acute respiratory distress syndrome
19. Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome
20. In vivo inhibition of nuclear factor-κB activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock
21. NF-κB is activated during acute inflammation in vivo in association with elevated endothelial cell adhesion molecule gene expression and leukocyte recruitment
22. NF-κB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome
23. Neutrophils are major contributors to intraparenchymal lung IL-1β expression after hemorrhage and endotoxemia
24. Biological markers of acute lung injury: Prognostic and pathogenetic significance
25. Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1
26. Scientific perspectives on the adult respiratory distress syndrome
27. Challenges in treating ARDS
28. Regulation of immune responses by NF-κB/Rel transcription factors
29. Hemorrhage induces rapid in vivo activation of CREB and NF-κB in murine intraparenchymal lung mononuclear cells
30. Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-κB, and CREB
31. Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury
32. Intravascular activation of complement and acute lung injury: Dependency on neutrophils and toxic oxygen intermediates
33. Cytokine expression by neutrophils and macrophages in vivo: Endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA express in acute lung inflammation