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Volumn 4, Issue 2, 2003, Pages 124-131

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; HISTONE H3; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

EID: 0037320925     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni876     Document Type: Article
Times cited : (512)

References (50)
  • 2
    • 0035962648 scopus 로고    scopus 로고
    • Chromatin silencing and activation by Polycomb and trithorax group proteins
    • Mahmoudi, T. & Verrijzer, C.P. Chromatin silencing and activation by Polycomb and trithorax group proteins. Oncogene 20, 3055-3066 (2001).
    • (2001) Oncogene , vol.20 , pp. 3055-3066
    • Mahmoudi, T.1    Verrijzer, C.P.2
  • 3
    • 0026762526 scopus 로고
    • Polycomb and polyhomeotic are constituents protein complex in chromatin of Drosophila melanogaster
    • Franke, A. et al. Polycomb and polyhomeotic are constituents protein complex in chromatin of Drosophila melanogaster. EMBO J. 11, 2941-2950 (1992).
    • (1992) EMBO J. , vol.11 , pp. 2941-2950
    • Franke, A.1
  • 4
    • 0031843056 scopus 로고    scopus 로고
    • Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: Indication for separate Pc-G complexes
    • van Lohuizen, M. et al. Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes. Mol. Cell. Biol. 18, 3572-3579 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3572-3579
    • van Lohuizen, M.1
  • 5
    • 0031842310 scopus 로고    scopus 로고
    • Characterization of interactions between the mammalian polycomb-group proteins Enx1/Ezh2 and EED suggests the existence of different mammalian polycomb-group protein complexes
    • Sewalt, R.G. et al. Characterization of interactions between the mammalian polycomb-group proteins Enx1/Ezh2 and EED suggests the existence of different mammalian polycomb-group protein complexes. Mol. Cell. Biol. 18, 3586-3595 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3586-3595
    • Sewalt, R.G.1
  • 6
    • 0033538578 scopus 로고    scopus 로고
    • Stabilization of chromatin structure by PRC1, a Polycomb complex
    • Shao, Z. et al. Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell 98, 37-46 (1999).
    • (1999) Cell , vol.98 , pp. 37-46
    • Shao, Z.1
  • 7
    • 0030772115 scopus 로고    scopus 로고
    • Functions of mammalian Polycomb group and trithorax group related genes
    • Gould, A. Functions of mammalian Polycomb group and trithorax group related genes. Curr. Opin. Genet. Dev. 7, 488-494 (1997).
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 488-494
    • Gould, A.1
  • 8
    • 0028201742 scopus 로고
    • Posterior transformation, neurological abnormalitites, and severe hematopoietic defects in mice with a targeted deletion of the bmi-I proto-oncogene
    • van der Lugt, N.M. et al. Posterior transformation, neurological abnormalitites, and severe hematopoietic defects in mice with a targeted deletion of the bmi-I proto-oncogene. Genes Dev. 8, 757-769 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 757-769
    • van der Lugt, N.M.1
  • 9
    • 0032543560 scopus 로고    scopus 로고
    • Male-to-female sex reversal in M33 mutant mice
    • Katoh-Fukui, Y. et al. Male-to-female sex reversal in M33 mutant mice. Nature 393, 688-692 (1998).
    • (1998) Nature , vol.393 , pp. 688-692
    • Katoh-Fukui, Y.1
  • 10
    • 0030849638 scopus 로고    scopus 로고
    • The role of mel-18, a mammalian Polycomb group gene, during IL-7 dependent proliferation of lymphocyte precursors
    • Akasaka, T. et al. The role of mel-18, a mammalian Polycomb group gene, during IL-7 dependent proliferation of lymphocyte precursors. Immunity 7, 135-146 (1997).
    • (1997) Immunity , vol.7 , pp. 135-146
    • Akasaka, T.1
  • 11
    • 0035172279 scopus 로고    scopus 로고
    • Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell development stage
    • Tokimasa, S. et al. Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell development stage. Exp. Hematol. 29, 93-103 (2001).
    • (2001) Exp. Hematol. , vol.29 , pp. 93-103
    • Tokimasa, S.1
  • 12
    • 0031049215 scopus 로고    scopus 로고
    • Altered cellular proliferation and mesoderm pattering in Polycomb-M33 deficient mice
    • Core, N. et al. Altered cellular proliferation and mesoderm pattering in Polycomb-M33 deficient mice. Development 124, 721-729 (1997).
    • (1997) Development , vol.124 , pp. 721-729
    • Core, N.1
  • 13
    • 0029899685 scopus 로고    scopus 로고
    • Interaction of Vav with ENX-I, a putative transcriptional regulator of homeobox gene expression
    • Hobert, O., Jallal, B. & Ullrich, A. Interaction of Vav with ENX-I, a putative transcriptional regulator of homeobox gene expression. Mol. Cell Biol. 16, 3066-3073 (1996).
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3066-3073
    • Hobert, O.1    Jallal, B.2    Ullrich, A.3
  • 14
    • 0029922115 scopus 로고    scopus 로고
    • Isolation and developmental expression analysis of Enx-I, a novel mouse Polycomb group gene
    • Hobert, O., Sures, I., Ciossek, T., Fuchs, M. & Ullrich, A. Isolation and developmental expression analysis of Enx-I, a novel mouse Polycomb group gene. Mech. Dev. 55, 171-184 (1996).
    • (1996) Mech. Dev. , vol.55 , pp. 171-184
    • Hobert, O.1    Sures, I.2    Ciossek, T.3    Fuchs, M.4    Ullrich, A.5
  • 15
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal polycomb Sites
    • Czermin, B. et al. Drosophila enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal polycomb Sites. Cell 111, 185-196 (2002).
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1
  • 16
    • 18644383738 scopus 로고    scopus 로고
    • Histone methyltransferase activity of a Drosophila polycomb group repressor complex
    • Muller, J. et al. Histone methyltransferase activity of a Drosophila polycomb group repressor complex. Cell 111, 197-208 (2002).
    • (2002) Cell , vol.111 , pp. 197-208
    • Muller, J.1
  • 17
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao, R. et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298, 1039-1043 (2000).
    • (2000) Science , vol.298 , pp. 1039-1043
    • Cao, R.1
  • 18
    • 0036532202 scopus 로고    scopus 로고
    • Histone methylation in transcription control
    • Kouzarides, T. Histone methylation in transcription control. Curr. Opin. Genet. 12, 198-209 (2002).
    • (2002) Curr. Opin. Genet. , vol.12 , pp. 198-209
    • Kouzarides, T.1
  • 19
    • 0034492916 scopus 로고    scopus 로고
    • Coexpression of BMI-I and Ezh2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease
    • Raaphors, F.M. et al. Coexpression of BMI-I and Ezh2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease. Am. J. Pathol. 157, 709-715 (2000).
    • (2000) Am. J. Pathol. , vol.157 , pp. 709-715
    • Raaphors, F.M.1
  • 20
    • 0034084913 scopus 로고    scopus 로고
    • Proliferative involvement of ENX-I, a putative human polycomb group gene, in haematopoietic cells
    • Fukuyama, T. et al. Proliferative involvement of ENX-I, a putative human polycomb group gene, in haematopoietic cells. Br. J. Haematol. 108, 842-847 (2000).
    • (2000) Br. J. Haematol. , vol.108 , pp. 842-847
    • Fukuyama, T.1
  • 21
    • 0034977239 scopus 로고    scopus 로고
    • The polycomb-group gene Ezh2 is required for early mouse development
    • O'Carroll,D. et al the polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol. 21, 4330-4336 (2001).
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4330-4336
    • O'Carroll, D.1
  • 22
    • 0027280936 scopus 로고
    • Independent control of immunogloblin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu, H., Zou, Y.R. & Rajewsky, K. Independent control of immunogloblin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73, 1155-1164 (1993).
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 23
    • 0030922630 scopus 로고    scopus 로고
    • Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
    • Laible, G. et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 16, 3219-3232 (1997).
    • (1997) EMBO J. , vol.16 , pp. 3219-3232
    • Laible, G.1
  • 24
    • 0028110864 scopus 로고
    • The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes
    • Tschiersch, B. et al. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13, 3822-3831 (1994).
    • (1994) EMBO J. , vol.13 , pp. 3822-3831
    • Tschiersch, B.1
  • 25
    • 0030478780 scopus 로고    scopus 로고
    • The Drosophila Enhancer of zeste gene encodes a chromosomal protein: Examination of wild-type and mutant protein distribution
    • Carrington, E.A. & Jones, R.S. The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122, 4073-4083 (1996).
    • (1996) Development , vol.122 , pp. 4073-4083
    • Carrington, E.A.1    Jones, R.S.2
  • 26
  • 27
    • 0033118752 scopus 로고    scopus 로고
    • The role of cytokine receptor signaling in lymphocyte development
    • Baird, A.M., Gerstein, R.M. & Berg, L.J. The role of cytokine receptor signaling in lymphocyte development. Curr. Opin. Immunol. 11, 157-166 (1999).
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 157-166
    • Baird, A.M.1    Gerstein, R.M.2    Berg, L.J.3
  • 28
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura, D., Roes, J., Kühn, R. & Rajewsky, K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350-426 (1991).
    • (1991) Nature , pp. 350-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 29
    • 0030888193 scopus 로고    scopus 로고
    • B cell development under the condition of allelic inclusion
    • Sonoda, E. et al. B cell development under the condition of allelic inclusion. Immunity 6, 225-233 (1997).
    • (1997) Immunity , vol.6 , pp. 225-233
    • Sonoda, E.1
  • 30
    • 0030818183 scopus 로고    scopus 로고
    • B lymphocyte-specific, Cre-mediated mutagenesis in mice
    • Rickert, R.C., Roes, J. & Rajewsky, K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25, 1317-1318 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1317-1318
    • Rickert, R.C.1    Roes, J.2    Rajewsky, K.3
  • 31
    • 0023054151 scopus 로고
    • VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay
    • Wu, G.E. & Paige, C.J. VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay. EMBO J. 5, 3475-3481 (1986).
    • (1986) EMBO J. , vol.5 , pp. 3475-3481
    • Wu, G.E.1    Paige, C.J.2
  • 32
    • 0028970728 scopus 로고
    • Mouse VH7183 recombination signal sequences mediate recombination more frequently than those of VHJ558
    • Connor, A.M. et al. Mouse VH7183 recombination signal sequences mediate recombination more frequently than those of VHJ558. J. Immunol. 155, 5268-5272 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 5268-5272
    • Connor, A.M.1
  • 33
    • 0027476466 scopus 로고
    • Immunoglobin heavy and light chain genes rearrange independently at early stages of B cell development
    • Ehlich, A et al Immunoglobin heavy and light chain genes rearrange independently at early stages of B cell development. Cell 72, 695-704 (1993).
    • (1993) Cell , vol.72 , pp. 695-704
    • Ehlich, A.1
  • 34
    • 0032006979 scopus 로고    scopus 로고
    • Nonsense surveillance in lymphocytes?
    • Li, S.& Wilkinson, M.F. Nonsense surveillance in lymphocytes? Immunity 8, 135-141 (1998).
    • (1998) Immunity , vol.8 , pp. 135-141
    • Li, S.1    Wilkinson, M.F.2
  • 35
    • 0031171282 scopus 로고    scopus 로고
    • Accessibility and the developmental regulation of V(D)J recombination
    • Schlissel, M.S. & Stanhope-Baker, P. Accessibility and the developmental regulation of V(D)J recombination. Semin. Immunol. 9, 161-170 (1997).
    • (1997) Semin. Immunol. , vol.9 , pp. 161-170
    • Schlissel, M.S.1    Stanhope-Baker, P.2
  • 36
    • 0035313998 scopus 로고    scopus 로고
    • How to make ends meet in V(D)J recombination
    • Grawunder, U. & Harfst, E. How to make ends meet in V(D)J recombination. Curr. Opin. Immunol. 13, 186-194 (2001).
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 186-194
    • Grawunder, U.1    Harfst, E.2
  • 37
    • 0025193019 scopus 로고
    • Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice
    • Malynn, B.A., Yancopoulos, G.D., Barth, J.E., Bona, C.A. & Alt, F.W. Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice. J. Exp. Med. 171. 843-859 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 843-859
    • Malynn, B.A.1    Yancopoulos, G.D.2    Barth, J.E.3    Bona, C.A.4    Alt, F.W.5
  • 38
    • 0029014910 scopus 로고
    • V(D)J recombination and the cell cycle
    • Lin, W.C. & Desiderio, S.V(D)J recombination and the cell cycle. Immunol. Today 16, 279-289 (1995).
    • (1995) Immunol. Today , vol.16 , pp. 279-289
    • Lin, W.C.1    Desiderio, S.2
  • 39
    • 0032567938 scopus 로고    scopus 로고
    • Impaired immunoglobin gene rearrangement in mice lacking the IL-7 receptor
    • Corcoran, A.E., Riddell, A., Krooshoop, D. & Venkitaraman, A.R. Impaired immunoglobin gene rearrangement in mice lacking the IL-7 receptor. Nature 391, 904-907 (1998).
    • (1998) Nature , vol.391 , pp. 904-907
    • Corcoran, A.E.1    Riddell, A.2    Krooshoop, D.3    Venkitaraman, A.R.4
  • 40
    • 0035890244 scopus 로고    scopus 로고
    • Stepwise activation of the immunoglobin mu heavy chain gene locus
    • Chowdhury, D. & Sen, R. Stepwise activation of the immunoglobin mu heavy chain gene locus. EMBO J. 20, 6394-6403 (2001).
    • (2001) EMBO J. , vol.20 , pp. 6394-6403
    • Chowdhury, D.1    Sen, R.2
  • 41
    • 0033103099 scopus 로고    scopus 로고
    • Interleukin-7: Physiological roles and mechanisms of action
    • Hofmeister, R. et al. Interleukin-7: physiological roles and mechanisms of action. Cytokine Growth Factor Rev. 10, 41-60 (1999).
    • (1999) Cytokine Growth Factor Rev. , vol.10 , pp. 41-60
    • Hofmeister, R.1
  • 42
    • 0035499655 scopus 로고    scopus 로고
    • Automatic identification of proteins with a MALDI-quadrupole ion trap mass spectrometer
    • Krutchinsky, A.N., Kalkum, M. & Chait, B.T. Automatic identification of proteins with a MALDI-quadrupole ion trap mass spectrometer. Anal. Chem. 73, 5066-5077 (2001).
    • (2001) Anal. Chem. , vol.73 , pp. 5066-5077
    • Krutchinsky, A.N.1    Kalkum, M.2    Chait, B.T.3
  • 43
    • 0034480770 scopus 로고    scopus 로고
    • Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification
    • Krutchinsky, A.N., Zhang, W. & Chait, B.T. Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification. J. Am. Soc. Mass Spectrom, 11, 493-504 (2000).
    • (2000) J. Am. Soc. Mass Spectrom. , vol.11 , pp. 493-504
    • Krutchinsky, A.N.1    Zhang, W.2    Chait, B.T.3
  • 44
    • 0037188911 scopus 로고    scopus 로고
    • Histone methylation: Dynamic or static?
    • Bannister, A.J., Schneider, R. & Kouzarides, T. Histone methylation: dynamic or static? Cell 109, 801-806 (2002).
    • (2002) Cell , vol.109 , pp. 801-806
    • Bannister, A.J.1    Schneider, R.2    Kouzarides, T.3
  • 45
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl, B.D. & Allis, C.D. The language of covalent histone modifications. Nature 403, 41-45 (2000).
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 46
    • 0037179692 scopus 로고    scopus 로고
    • Acetylation of histone H4 by Esa I is required for DNA double-stand break repair
    • Bird, A.W. et al. Acetylation of histone H4 by Esa I is required for DNA double-stand break repair. Nature 419, 411-415 (2002).
    • (2002) Nature , vol.419 , pp. 411-415
    • Bird, A.W.1
  • 47
    • 0037145016 scopus 로고    scopus 로고
    • Methylation of histone H3 at lysine 9 targets programmed DNA elimination in tetrahymena
    • Taverna, S.D., Coyne, R.S. & Allis, C.D. Methylation of histone H3 at lysine 9 targets programmed DNA elimination in tetrahymena. Cell 110,701-711 (2002).
    • (2002) Cell , vol.110 , pp. 701-711
    • Taverna, S.D.1    Coyne, R.S.2    Allis, C.D.3
  • 48
    • 0036359284 scopus 로고    scopus 로고
    • Cre/loxP recombination system and gene targeting
    • Torres, R.M. & Kühn, R. Cre/loxP recombination system and gene targeting. Meth. Mol. Biol. 180, 175-204 (2002).
    • (2002) Meth. Mol. Biol. , vol.180 , pp. 175-204
    • Torres, R.M.1    Kühn, R.2
  • 49


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