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Volumn 185, Issue 11, 1997, Pages 2025-2032

V(D)J recombination: Modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 0030980386     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.11.2025     Document Type: Article
Times cited : (121)

References (35)
  • 1
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological and comparative analysis
    • Lewis, S.M. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological and comparative analysis. Adv. Immunol. 56:27-150.
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 2
    • 0029886929 scopus 로고    scopus 로고
    • Mechanism of V(D)J recombination
    • Bogue, M., and D.B. Roth. 1996. Mechanism of V(D)J recombination. Curr. Opin. Immunol. 8:175-180.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 175-180
    • Bogue, M.1    Roth, D.B.2
  • 3
    • 0028805853 scopus 로고
    • Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
    • McBlane, J.F., D.C. van Gent, D.A. Ramsden, C. Romeo, C.A. Cuomo, M. Gellert, and M.A. Oettinger. 1995. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell. 83:387-395.
    • (1995) Cell , vol.83 , pp. 387-395
    • McBlane, J.F.1    Van Gent, D.C.2    Ramsden, D.A.3    Romeo, C.4    Cuomo, C.A.5    Gellert, M.6    Oettinger, M.A.7
  • 5
    • 0001265782 scopus 로고    scopus 로고
    • RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination
    • Difilippantonio, M.J., C.J. McMahan, Q.M. Eastman, E. Spanopoulou, and D. Schatz. 1996. RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination. Cell. 87:253-262.
    • (1996) Cell , vol.87 , pp. 253-262
    • Difilippantonio, M.J.1    McMahan, C.J.2    Eastman, Q.M.3    Spanopoulou, E.4    Schatz, D.5
  • 6
    • 0030592523 scopus 로고    scopus 로고
    • The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination
    • Spanopolou, E., F. Zaitseta, F.-H. Wang, S. Santagata, D. Baltimore, and G. Panayotou. 1996. The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination. Cell. 87:263-276.
    • (1996) Cell , vol.87 , pp. 263-276
    • Spanopolou, E.1    Zaitseta, F.2    Wang, F.-H.3    Santagata, S.4    Baltimore, D.5    Panayotou, G.6
  • 7
    • 0030964130 scopus 로고    scopus 로고
    • A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
    • Hiom, K., and M. Gellert. 1996. A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage. Cell. 88:65-72.
    • (1996) Cell , vol.88 , pp. 65-72
    • Hiom, K.1    Gellert, M.2
  • 8
    • 0023659483 scopus 로고
    • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals
    • Hesse, J.E., M.R. Lieber, M. Gellert, and K. Mizuuchi. 1987. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell. 49: 775-783.
    • (1987) Cell , vol.49 , pp. 775-783
    • Hesse, J.E.1    Lieber, M.R.2    Gellert, M.3    Mizuuchi, K.4
  • 9
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature (Lond.). 302:575-581.
    • (1983) Nature (Lond.) , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 10
    • 0029864993 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vitro obeying the 12/23 rule
    • Eastman, Q.M., T.M. L. Leu, and D.G. Schatz. 1996. Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature (Lond.). 380:85-88.
    • (1996) Nature (Lond.) , vol.380 , pp. 85-88
    • Eastman, Q.M.1    Leu, T.M.L.2    Schatz, D.G.3
  • 11
    • 0030155949 scopus 로고    scopus 로고
    • The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo
    • Steen, S.B., L. Gomelsky, and D.B. Roth. 1996. The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo. Genes to Cells. 1:543-553.
    • (1996) Genes to Cells , vol.1 , pp. 543-553
    • Steen, S.B.1    Gomelsky, L.2    Roth, D.B.3
  • 12
    • 0030009253 scopus 로고    scopus 로고
    • The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
    • van Gent, D.C., D.A. Ramsden, and M. Gellert. 1996. The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell. 85:107-113.
    • (1996) Cell , vol.85 , pp. 107-113
    • Van Gent, D.C.1    Ramsden, D.A.2    Gellert, M.3
  • 13
    • 0026792892 scopus 로고
    • V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • Roth, D.B., J.P. Menetski, P.B. Nakajima, M.J. Bosma, and M. Gellert. 1992(a). V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell. 70:983-991.
    • (1992) Cell , vol.70 , pp. 983-991
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.B.3    Bosma, M.J.4    Gellert, M.5
  • 14
    • 0026762509 scopus 로고
    • V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals
    • Roth, D.B., P.B. Nakajima, J.P. Menetski, M.J. Bosma, and M. Gellert. 1992(b). V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor δ rearrangement signals. Cell. 69:41-53.
    • (1992) Cell , vol.69 , pp. 41-53
    • Roth, D.B.1    Nakajima, P.B.2    Menetski, J.P.3    Bosma, M.J.4    Gellert, M.5
  • 15
    • 0027491330 scopus 로고
    • Characterization of broken DNA molecules associated with V(D)J recombination
    • Roth, D.B., C. Zhu, and M. Gellert. 1993. Characterization of broken DNA molecules associated with V(D)J recombination. Proc. Natl. Acad. Sci. USA. 90:10788-10792.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10788-10792
    • Roth, D.B.1    Zhu, C.2    Gellert, M.3
  • 16
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., U.A. Constantinesc, T. Morrow, M. Baxter, and A. Peng. 1993. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7:2520-2532.
    • (1993) Genes Dev. , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinesc, U.A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 17
    • 0029967722 scopus 로고    scopus 로고
    • Similarities between initiation of V(D)J recombination and retroviral integration
    • van Gent, D.C., K. Mizuuchi, and M. Gellert. 1996. Similarities between initiation of V(D)J recombination and retroviral integration. Science (Wash. DC). 271:1592-1594.
    • (1996) Science (Wash. DC) , vol.271 , pp. 1592-1594
    • Van Gent, D.C.1    Mizuuchi, K.2    Gellert, M.3
  • 18
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
    • Li, Z., T. Otevrel, Y. Gao, H.-L. Cheng, B. Seed, T.D. Stamoto, G.E. Taccioli, and F. Alt. 1995. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell. 83:1079-1089.
    • (1995) Cell , vol.83 , pp. 1079-1089
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.-L.4    Seed, B.5    Stamoto, T.D.6    Taccioli, G.E.7    Alt, F.8
  • 19
    • 0028043678 scopus 로고
    • Prokaryotic HU and eukaryotic HMG1: A kinked relationship
    • Bianchi, M.B. 1994. Prokaryotic HU and eukaryotic HMG1: a kinked relationship. Mol. Microbiol. 14:1-5.
    • (1994) Mol. Microbiol. , vol.14 , pp. 1-5
    • Bianchi, M.B.1
  • 20
    • 0026637325 scopus 로고
    • Transpositional recombination: Mechanistic insights from studies of Mu and other elements
    • Mizuuchi., K. 1992. Transpositional recombination: mechanistic insights from studies of Mu and other elements. Annu. Rev. Biochem. 61:1011-1051.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 1011-1051
    • Mizuuchi, K.1
  • 21
    • 0027236954 scopus 로고
    • Production of high titer helper-free retrovirus by transient transfection
    • Pear, W., G. Nolan, M. Scott, and D. Baltimore. 1993. Production of high titer helper-free retrovirus by transient transfection. Proc. Natl. Acad. Sci. USA. 90:8392-8395.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8395
    • Pear, W.1    Nolan, G.2    Scott, M.3    Baltimore, D.4
  • 23
    • 0015763884 scopus 로고
    • Isolation and characterisation of two calf-thymus chromatin non-histone proteins with high content of acidic and basic amino acids
    • Goodwin, G.H., and E.W. Johns. 1973. Isolation and characterisation of two calf-thymus chromatin non-histone proteins with high content of acidic and basic amino acids. Eur. J. Biochem. 40:215-219.
    • (1973) Eur. J. Biochem. , vol.40 , pp. 215-219
    • Goodwin, G.H.1    Johns, E.W.2
  • 24
    • 0022423921 scopus 로고
    • Hierarchy of binding sites for chromosomal proteins HMG 1 and 2 in supercoiled deoxyribonucleic acid
    • Hamada, H., and M. Bustin. 1985. Hierarchy of binding sites for chromosomal proteins HMG 1 and 2 in supercoiled deoxyribonucleic acid. Biochemistry 24:1428-1433.
    • (1985) Biochemistry , vol.24 , pp. 1428-1433
    • Hamada, H.1    Bustin, M.2
  • 26
    • 0029843541 scopus 로고    scopus 로고
    • Activator-dependent transcription by mammalian RNA polymerase II: In vitro reconstitution with general transcription factors and cofactors
    • Ge, H., E. Martinez, C.-M. Chiang, and R.G. Roeder. 1996. Activator-dependent transcription by mammalian RNA polymerase II: in vitro reconstitution with general transcription factors and cofactors. Meth. Enzymol 274:57-71.
    • (1996) Meth. Enzymol , vol.274 , pp. 57-71
    • Ge, H.1    Martinez, E.2    Chiang, C.-M.3    Roeder, R.G.4
  • 27
    • 0028303884 scopus 로고
    • The high mobility group protein HMG-1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
    • Ge, H., and R.G. Roeder. 1994. The high mobility group protein HMG-1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. J. Biol. Chem. 269:17136-17140.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17136-17140
    • Ge, H.1    Roeder, R.G.2
  • 29
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combine immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., M.A. Bogue, D.-S. Lim, P. Hasty, and D.B. Roth. 1996. Ku86-deficient mice exhibit severe combine immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86:379-390.
    • (1996) Cell , vol.86 , pp. 379-390
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5
  • 30
    • 0027229357 scopus 로고
    • DNA looping and the helical repeat in vitro and in vivo: Effect of HU protein and enhancer location on Hin invertosome assembly
    • Haykinson, M.J., and R.C. Johnson. 1993. DNA looping and the helical repeat in vitro and in vivo: effect of HU protein and enhancer location on Hin invertosome assembly. EMBO (Eur. Mol. Biol. Organ.) J. 12:2503-2512.
    • (1993) EMBO (Eur. Mol. Biol. Organ.) J. , vol.12 , pp. 2503-2512
    • Haykinson, M.J.1    Johnson, R.C.2
  • 31
    • 0028147923 scopus 로고
    • Architectural elements in nucleoprotein complexes: Interchange-ability of specific and nonspecific DNA binding proteins
    • Segal, A.M., S.D. Goodman, and H.A. Nash. 1994. Architectural elements in nucleoprotein complexes: interchange-ability of specific and nonspecific DNA binding proteins. EMBO (Eur. Mol. Biol. Organ.) J. 13:4536-4548.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 4536-4548
    • Segal, A.M.1    Goodman, S.D.2    Nash, H.A.3
  • 32
    • 0028197368 scopus 로고
    • HMG domain proteins: Architectural elements in the assembly of nucleoprotein structures
    • Grosschedl, R., K. Giese, and J. Pagel. 1994. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10:94-100.
    • (1994) Trends Genet. , vol.10 , pp. 94-100
    • Grosschedl, R.1    Giese, K.2    Pagel, J.3
  • 33
    • 0030584463 scopus 로고    scopus 로고
    • V(D)J recombination and transposition: Closer than expected
    • Craig N.L. 1996. V(D)J recombination and transposition: closer than expected. Science (Wash. DC). 271:1592-1594.
    • (1996) Science (Wash. DC) , vol.271 , pp. 1592-1594
    • Craig, N.L.1
  • 34
    • 0028302290 scopus 로고
    • A second high affinity HU binding site in the phage Mu transpososome
    • Lavoie, B.D., and G. Chaconas. 1994. A second high affinity HU binding site in the phage Mu transpososome. J. Biol. Chem. 269:15571-15576.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15571-15576
    • Lavoie, B.D.1    Chaconas, G.2
  • 35
    • 0030451819 scopus 로고    scopus 로고
    • Crystal structure of an IHF-DNA complex: A protein-induced DNA U-turn
    • Rice, P.A., S. Yang, K. Mizuuchi, and H.A. Nash. 1996. Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn. Cell 87:1295-1306.
    • (1996) Cell , vol.87 , pp. 1295-1306
    • Rice, P.A.1    Yang, S.2    Mizuuchi, K.3    Nash, H.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.