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Volumn 22, Issue , 2004, Pages 55-79

Transcriptional control of early B cell development

Author keywords

E2A; EBF; Ikaros; Pax5; PU.1

Indexed keywords

CELL RECEPTOR; HISTONE; IKAROS TRANSCRIPTION FACTOR; IMMUNOGLOBULIN HEAVY CHAIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 7 RECEPTOR ALPHA; LYMPHOID ENHANCER FACTOR 1; RECEPTOR PROTEIN; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR EBF; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR SOX4; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3; WNT PROTEIN;

EID: 2542442633     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.22.012703.104807     Document Type: Review
Times cited : (391)

References (151)
  • 1
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K. 1997. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91:661-72
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 2
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. 2000. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404:193-97
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 4
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    • Christensen JL, Weissman IL. 2001. Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. USA 98:14541-46
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 5
    • 0036669273 scopus 로고    scopus 로고
    • Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
    • Igarashi H, Gregory SC, Yokota T, Sakaguchi N, Kincade PW 2002. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17:117-30
    • (2002) Immunity , vol.17 , pp. 117-130
    • Igarashi, H.1    Gregory, S.C.2    Yokota, T.3    Sakaguchi, N.4    Kincade, P.W.5
  • 7
    • 0034670385 scopus 로고    scopus 로고
    • Development of CD8α-positive dendritic cells from a common myeloid progenitor
    • Traver D, Akashi K, Manz M, Merad M, Miyamoto T, et al. 2000. Development of CD8α-positive dendritic cells from a common myeloid progenitor. Science 290:2152-54
    • (2000) Science , vol.290 , pp. 2152-2154
    • Traver, D.1    Akashi, K.2    Manz, M.3    Merad, M.4    Miyamoto, T.5
  • 10
    • 0030483542 scopus 로고    scopus 로고
    • Identification of the earliest B lineage stage in mouse bone marrow
    • Li Y-S, Wasserman R, Hayakawa K, Hardy RR. 1996. Identification of the earliest B lineage stage in mouse bone marrow. Immunity 5:527-35
    • (1996) Immunity , vol.5 , pp. 527-535
    • Li, Y.-S.1    Wasserman, R.2    Hayakawa, K.3    Hardy, R.R.4
  • 11
    • 0033711666 scopus 로고    scopus 로고
    • Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation events
    • Tudor KS, Payne KJ, Yamashita Y, Kincade PW. 2000. Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation events. Immunity 12:335-45
    • (2000) Immunity , vol.12 , pp. 335-345
    • Tudor, K.S.1    Payne, K.J.2    Yamashita, Y.3    Kincade, P.W.4
  • 12
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Kayakawa K. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213-25
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Kayakawa, K.5
  • 13
    • 0027275497 scopus 로고
    • The regulated expression of B lineage-associated genes during B cell differentiation in bone marrow and fetal liver
    • Li Y-S, Hayakawa K, Hardy RR. 1993. The regulated expression of B lineage-associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 178:951-60
    • (1993) J. Exp. Med. , vol.178 , pp. 951-960
    • Li, Y.-S.1    Hayakawa, K.2    Hardy, R.R.3
  • 15
    • 0034684662 scopus 로고    scopus 로고
    • Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other
    • Domen J, Weissman IL. 2000. Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J. Exp. Med. 192:1707-18
    • (2000) J. Exp. Med. , vol.192 , pp. 1707-1718
    • Domen, J.1    Weissman, I.L.2
  • 17
    • 0034210658 scopus 로고    scopus 로고
    • Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
    • McKenna HJ, Stocking KL, Miller RE, Brasel K, De Smedt T, et al. 2000. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. Blood 95:3489-97
    • (2000) Blood , vol.95 , pp. 3489-3497
    • McKenna, H.J.1    Stocking, K.L.2    Miller, R.E.3    Brasel, K.4    De Smedt, T.5
  • 18
    • 0036797682 scopus 로고    scopus 로고
    • Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool
    • Sitnicka E, Bryder D, Theilgaard-Mönch K, Buza-Vidas N, Adolfsson J, Jacobsen SEW. 2002. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity 17:463-72
    • (2002) Immunity , vol.17 , pp. 463-472
    • Sitnicka, E.1    Bryder, D.2    Theilgaard-Mönch, K.3    Buza-Vidas, N.4    Adolfsson, J.5    Sew, J.6
  • 19
    • 0036719077 scopus 로고    scopus 로고
    • The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7
    • Miller JP, Izon D, DeMuth W, Gerstein R, Bhandoola A, Allman D. 2002. The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7. J. Exp. Med. 196:705-11
    • (2002) J. Exp. Med. , vol.196 , pp. 705-711
    • Miller, J.P.1    Izon, D.2    Demuth, W.3    Gerstein, R.4    Bhandoola, A.5    Allman, D.6
  • 21
  • 22
    • 0029097145 scopus 로고
    • Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
    • Mackarehtschian K, Hardin JD, Moore KA, Boast S, Goff SP, Lemischka IR. 1995. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3:147-61
    • (1995) Immunity , vol.3 , pp. 147-161
    • Mackarehtschian, K.1    Hardin, J.D.2    Moore, K.A.3    Boast, S.4    Goff, S.P.5    Lemischka, I.R.6
  • 24
    • 0036519296 scopus 로고    scopus 로고
    • Haematopoietic cell-fate decisions, chromatin regulation and Ikaros
    • Georgopoulos K. 2002. Haematopoietic cell-fate decisions, chromatin regulation and Ikaros. Nat. Rev. Immunol. 2:162-74
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 162-174
    • Georgopoulos, K.1
  • 25
    • 0030972497 scopus 로고    scopus 로고
    • Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation
    • Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, et al. 1997. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J. 16:2004-13
    • (1997) EMBO J. , vol.16 , pp. 2004-2013
    • Morgan, B.1    Sun, L.2    Avitahl, N.3    Andrikopoulos, K.4    Ikeda, T.5
  • 26
    • 0032560018 scopus 로고    scopus 로고
    • Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
    • Kelley CM, Ikeda T, Koipally J, Avitahl N, Wu L, et al. 1998. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 8:508-15
    • (1998) Curr. Biol. , vol.8 , pp. 508-515
    • Kelley, C.M.1    Ikeda, T.2    Koipally, J.3    Avitahl, N.4    Wu, L.5
  • 27
    • 0031907815 scopus 로고    scopus 로고
    • Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes
    • Klug CA, Morrison SJ, Masek M, Hahm K, Smale ST, Weissman IL. 1998. Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Proc. Natl. Acad. Sci. USA 95:657-62
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 657-662
    • Klug, C.A.1    Morrison, S.J.2    Masek, M.3    Hahm, K.4    Smale, S.T.5    Weissman, I.L.6
  • 28
    • 0029831978 scopus 로고    scopus 로고
    • Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development
    • Sun L, Liu A, Georgopoulos K. 1996. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J. 15:5358-69
    • (1996) EMBO J. , vol.15 , pp. 5358-5369
    • Sun, L.1    Liu, A.2    Georgopoulos, K.3
  • 29
    • 0028001362 scopus 로고
    • The Ikaros gene is required for the development of all lymphoid lineages
    • Georgopoulos K, Bigby M, Wang J-H, Molnar A, Wu P, et al. 1994. The Ikaros gene is required for the development of all lymphoid lineages. Cell 79:143-56
    • (1994) Cell , vol.79 , pp. 143-156
    • Georgopoulos, K.1    Bigby, M.2    Wang, J.-H.3    Molnar, A.4    Wu, P.5
  • 30
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang J-H, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, et al. 1996. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5:537-49
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.-H.1    Nichogiannopoulou, A.2    Wu, L.3    Sun, L.4    Sharpe, A.H.5
  • 31
    • 0030703546 scopus 로고    scopus 로고
    • Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage
    • Wu L, Nichogiannopoulou A, Shortman K, Georgopoulos K. 1997. Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage. Immunity 7:483-92
    • (1997) Immunity , vol.7 , pp. 483-492
    • Wu, L.1    Nichogiannopoulou, A.2    Shortman, K.3    Georgopoulos, K.4
  • 34
    • 0032191170 scopus 로고    scopus 로고
    • Aiolos regulates B cell activation and maturation to effector state
    • Wang JH, Avitahl N, Cariappa A, Friedrich C, Ikeda T, et al. 1998. Aiolos regulates B cell activation and maturation to effector state. Immunity 9:543-53
    • (1998) Immunity , vol.9 , pp. 543-553
    • Wang, J.H.1    Avitahl, N.2    Cariappa, A.3    Friedrich, C.4    Ikeda, T.5
  • 36
    • 0037443458 scopus 로고    scopus 로고
    • Ikaros regulates neutrophil differentiation
    • Dumortier A, Kirstetter P, Kastner P, Chan S. 2003. Ikaros regulates neutrophil differentiation. Blood 101:2219-26
    • (2003) Blood , vol.101 , pp. 2219-2226
    • Dumortier, A.1    Kirstetter, P.2    Kastner, P.3    Chan, S.4
  • 37
    • 0033152491 scopus 로고    scopus 로고
    • Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
    • Koipally J, Renold A, Kim J, Georgopoulos K. 1999. Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes. EMBO J. 18:3090-100
    • (1999) EMBO J. , vol.18 , pp. 3090-3100
    • Koipally, J.1    Renold, A.2    Kim, J.3    Georgopoulos, K.4
  • 38
    • 0033103374 scopus 로고    scopus 로고
    • Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
    • Kim J, Sif S, Jones B, Jackson A, Koipally J, et al. 1999. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10:345-55
    • (1999) Immunity , vol.10 , pp. 345-355
    • Kim, J.1    Sif, S.2    Jones, B.3    Jackson, A.4    Koipally, J.5
  • 39
    • 0034733563 scopus 로고    scopus 로고
    • Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity
    • Koipally J, Georgopoulos K. 2000. Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. J. Biol. Chem. 275:19594-602
    • (2000) J. Biol. Chem. , vol.275 , pp. 19594-19602
    • Koipally, J.1    Georgopoulos, K.2
  • 40
    • 0036886895 scopus 로고    scopus 로고
    • The CD8α gene locus is regulated by the Ikaros family of proteins
    • Harker N, Naito T, Cortes M, Hostert A, Hirschberg S, et al. 2002. The CD8α gene locus is regulated by the Ikaros family of proteins. Mol. Cell 10:1403-15
    • (2002) Mol. Cell , vol.10 , pp. 1403-1415
    • Harker, N.1    Naito, T.2    Cortes, M.3    Hostert, A.4    Hirschberg, S.5
  • 41
    • 0031437119 scopus 로고    scopus 로고
    • Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
    • Brown KE, Guest SS, Smale ST, Hahm K, Merkenschlager M, Fisher AG. 1997. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 91:845-54
    • (1997) Cell , vol.91 , pp. 845-854
    • Brown, K.E.1    Guest, S.S.2    Smale, S.T.3    Hahm, K.4    Merkenschlager, M.5    Fisher, A.G.6
  • 43
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott EW, Simon MC, Anastasi J, Singh H. 1994. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265:1573-77
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 44
    • 0242549003 scopus 로고    scopus 로고
    • Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
    • McKercher SR, Torbett BE, Anderson KL, Henkel GW, Vestal DJ, et al. 1996. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 15:5647-6658
    • (1996) EMBO J. , vol.15 , pp. 5647-6658
    • McKercher, S.R.1    Torbett, B.E.2    Anderson, K.L.3    Henkel, G.W.4    Vestal, D.J.5
  • 45
    • 0027363528 scopus 로고
    • Hematopoietic lineage- and stage-restricted expression of the ETS oncogen family member PU.1
    • Hromas R, Orazi A, Neiman R, Maki R, Van Beveran C, et al. 1993. Hematopoietic lineage- and stage-restricted expression of the ETS oncogen family member PU.1. Blood 82:2998-3004
    • (1993) Blood , vol.82 , pp. 2998-3004
    • Hromas, R.1    Orazi, A.2    Neiman, R.3    Maki, R.4    Van Beveran, C.5
  • 46
    • 0032784934 scopus 로고    scopus 로고
    • Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage
    • Anderson MK, Hernandez-Hoyos G, Diamond RA, Rothenberg EV. 1999. Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage. Development 126:3131-48
    • (1999) Development , vol.126 , pp. 3131-3148
    • Anderson, M.K.1    Hernandez-Hoyos, G.2    Diamond, R.A.3    Rothenberg, E.V.4
  • 47
    • 0030611964 scopus 로고    scopus 로고
    • PU.1 functions in a cell-autonomous manner to control the differentiation of multi-potential lymphoid-myeloid progenitors
    • Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H. 1997. PU.1 functions in a cell-autonomous manner to control the differentiation of multi-potential lymphoid-myeloid progenitors. Immunity 6:437-47
    • (1997) Immunity , vol.6 , pp. 437-447
    • Scott, E.W.1    Fisher, R.C.2    Olson, M.C.3    Kehrli, E.W.4    Simon, M.C.5    Singh, H.6
  • 48
  • 49
    • 18744416572 scopus 로고    scopus 로고
    • Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates
    • Walsh JC, DeKoter RP, Lee HJ, Smith ED, Lancki DW, et al. 2002. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity 17:665-76
    • (2002) Immunity , vol.17 , pp. 665-676
    • Walsh, J.C.1    DeKoter, R.P.2    Lee, H.J.3    Smith, E.D.4    Lancki, D.W.5
  • 50
    • 0032479989 scopus 로고    scopus 로고
    • PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors
    • DeKoter RP, Walsh JC, Singh H. 1998. PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. EMBO J. 17:4456-68
    • (1998) EMBO J. , vol.17 , pp. 4456-4468
    • DeKoter, R.P.1    Walsh, J.C.2    Singh, H.3
  • 51
    • 0035353208 scopus 로고    scopus 로고
    • Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells
    • Colucci F, Samson SI, DeKoter RP, Lantz O, Singh H, Di Santo JP. 2001. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood 97:2625-32
    • (2001) Blood , vol.97 , pp. 2625-2632
    • Colucci, F.1    Samson, S.I.2    DeKoter, R.P.3    Lantz, O.4    Singh, H.5    Di Santo, J.P.6
  • 53
    • 0036199657 scopus 로고    scopus 로고
    • PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
    • DeKoter RP, Lee H-J, Singh H. 2002. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 16:297-309
    • (2002) Immunity , vol.16 , pp. 297-309
    • DeKoter, R.P.1    Lee, H.-J.2    Singh, H.3
  • 54
    • 0034717335 scopus 로고    scopus 로고
    • Regulation of B lymphocyte and macrophage development by graded expression of PU.1
    • DeKoter RP, Singh H. 2000. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288:1439-41
    • (2000) Science , vol.288 , pp. 1439-1441
    • DeKoter, R.P.1    Singh, H.2
  • 55
    • 0024554495 scopus 로고
    • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    • Murre C, McCaw PS, Baltimore D. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777-83
    • (1989) Cell , vol.56 , pp. 777-783
    • Murre, C.1    McCaw, P.S.2    Baltimore, D.3
  • 56
    • 0029058035 scopus 로고
    • B-cell-specific DNA binding by an E47 homodimer
    • Shen CP, Kadesch T. 1995. B-cell-specific DNA binding by an E47 homodimer. Mol. Cell. Biol. 15:4518-24
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4518-4524
    • Shen, C.P.1    Kadesch, T.2
  • 57
    • 0029912857 scopus 로고    scopus 로고
    • Phosphorylation of E47 as a potential determinant of B-cell-specific activity
    • Sloan SR, Shen C-P, McCarrick-Walmsley R, Kadesch T. 1996. Phosphorylation of E47 as a potential determinant of B-cell-specific activity. Mol. Cell. Biol. 16:6900-8
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6900-6908
    • Sloan, S.R.1    Shen, C.-P.2    McCarrick-Walmsley, R.3    Kadesch, T.4
  • 58
    • 0031867289 scopus 로고    scopus 로고
    • Functional replacement of the mouse E2A gene with a human HEB cDNA
    • Zhuang Y, Barndt RJ, Pan L, Kelley R, Dai M. 1998. Functional replacement of the mouse E2A gene with a human HEB cDNA. Mol. Cell. Biol. 18:3340-49
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3340-3349
    • Zhuang, Y.1    Barndt, R.J.2    Pan, L.3    Kelley, R.4    Dai, M.5
  • 59
    • 0027992622 scopus 로고
    • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
    • Bain G, Maandag ECR, Izon DJ, Amsen D, Kruisbeek AM, et al. 1994. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79:885-92
    • (1994) Cell , vol.79 , pp. 885-892
    • Bain, G.1    Maandag, E.C.R.2    Izon, D.J.3    Amsen, D.4    Kruisbeek, A.M.5
  • 60
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H. 1994. The helix-loop-helix gene E2A is required for B cell formation. Cell 79:875-84
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 62
    • 0029896451 scopus 로고    scopus 로고
    • B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2 and HEB
    • Zhuang Y, Cheng P, Weintraub H. 1996. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2 and HEB. Mol. Cell. Biol. 16:2898-905
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2898-2905
    • Zhuang, Y.1    Cheng, P.2    Weintraub, H.3
  • 63
    • 0027229972 scopus 로고
    • Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression
    • Hagman J, Belanger C, Travis A, Turck CW, Grosschedl R. 1993. Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev. 7:760-73
    • (1993) Genes Dev. , vol.7 , pp. 760-773
    • Hagman, J.1    Belanger, C.2    Travis, A.3    Turck, C.W.4    Grosschedl, R.5
  • 64
    • 0029076534 scopus 로고
    • EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains
    • Hagman J, Gutch MJ, Lin H, Grosschedl R. 1995. EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains. EMBO J. 14:2907-16
    • (1995) EMBO J. , vol.14 , pp. 2907-2916
    • Hagman, J.1    Gutch, M.J.2    Lin, H.3    Grosschedl, R.4
  • 65
    • 0029045161 scopus 로고
    • Failure of B-cell differentiation in mice lacking the transcription factor EBF
    • Lin H, Grosschedl R. 1995. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 376:263-67
    • (1995) Nature , vol.376 , pp. 263-267
    • Lin, H.1    Grosschedl, R.2
  • 66
    • 0033166301 scopus 로고    scopus 로고
    • Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A
    • O'Riordan M, Grosschedl R. 1999. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity 11:21-31
    • (1999) Immunity , vol.11 , pp. 21-31
    • O'Riordan, M.1    Grosschedl, R.2
  • 67
    • 0026045243 scopus 로고
    • Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T cell line
    • Schlissel M, Voronova A, Baltimore D. 1991. Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T cell line. Genes Dev. 5:1367-76
    • (1991) Genes Dev. , vol.5 , pp. 1367-1376
    • Schlissel, M.1    Voronova, A.2    Baltimore, D.3
  • 69
    • 0032541471 scopus 로고    scopus 로고
    • Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12
    • Kee BL, Murre C. 1998. Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12. J. Exp. Med. 188:699-713
    • (1998) J. Exp. Med. , vol.188 , pp. 699-713
    • Kee, B.L.1    Murre, C.2
  • 70
    • 0030790713 scopus 로고    scopus 로고
    • EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes
    • Sigvardsson M, O'Riordan M, Grosschedl R. 1997. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity 7:25-36
    • (1997) Immunity , vol.7 , pp. 25-36
    • Sigvardsson, M.1    O'Riordan, M.2    Grosschedl, R.3
  • 71
    • 0034099044 scopus 로고    scopus 로고
    • Overlapping expression of early B-cell factor and basic helix-loop-helix proteins as a mechanism to dictate B-lineage-specific activity of the A.5 promoter
    • Sigvardsson M. 2000. Overlapping expression of early B-cell factor and basic helix-loop-helix proteins as a mechanism to dictate B-lineage-specific activity of the A.5 promoter. Mol. Cell. Biol. 20:3640-54
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3640-3654
    • Sigvardsson, M.1
  • 72
    • 0037093872 scopus 로고    scopus 로고
    • The human V-preB promoter is a target for coordinated activation by early B cell factor and E47
    • Gisler R, Sigvardsson M. 2002. The human V-preB promoter is a target for coordinated activation by early B cell factor and E47. J. Immunol. 168:5130-38
    • (2002) J. Immunol. , vol.168 , pp. 5130-5138
    • Gisler, R.1    Sigvardsson, M.2
  • 73
    • 18744388827 scopus 로고    scopus 로고
    • Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B-cell-specific mb-1 promoter
    • Sigvardsson M, Clark DR, Fitzsimmons D, Doyle M, Akerblad P, et al. 2002. Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B-cell-specific mb-1 promoter. Mol. Cell. Biol. 22:8539-51
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 8539-8551
    • Sigvardsson, M.1    Clark, D.R.2    Fitzsimmons, D.3    Doyle, M.4    Akerblad, P.5
  • 74
    • 0032909652 scopus 로고    scopus 로고
    • The B29 (immunoglobulin β-chain) gene is a genetic target for early B-cell factor
    • Akerblad P, Rosberg M, Leanderson T, Sigvardsson M. 1999. The B29 (immunoglobulin β-chain) gene is a genetic target for early B-cell factor. Mol. Cell. Biol. 19:392-401
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 392-401
    • Akerblad, P.1    Rosberg, M.2    Leanderson, T.3    Sigvardsson, M.4
  • 75
    • 0037069382 scopus 로고    scopus 로고
    • Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system
    • Greenbaum S, Zhuang Y. 2002. Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system. Proc. Natl. Acad. Sci. USA 99:15030-35
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15030-15035
    • Greenbaum, S.1    Zhuang, Y.2
  • 76
    • 0025238437 scopus 로고
    • The protein Id: A negative regulator of helix-loop-helix DNA-binding proteins
    • Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H. 1990. The protein Id: a negative regulator of helix-loop-helix DNA-binding proteins. Cell 61:49-59
    • (1990) Cell , vol.61 , pp. 49-59
    • Benezra, R.1    Davis, R.L.2    Lockshon, D.3    Turner, D.L.4    Weintraub, H.5
  • 77
    • 0028088556 scopus 로고
    • Constitutive expression of the Id1 gene impairs mouse B cell development
    • Sun X-H. 1994. Constitutive expression of the Id1 gene impairs mouse B cell development. Cell 79:893-900
    • (1994) Cell , vol.79 , pp. 893-900
    • Sun, X.-H.1
  • 78
    • 0035289643 scopus 로고    scopus 로고
    • Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-β
    • Kee BL, Rivera RR, Murre C. 2001. Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-β. Nat. Immunol. 2:242-41
    • (2001) Nat. Immunol. , vol.2 , pp. 242-341
    • Kee, B.L.1    Rivera, R.R.2    Murre, C.3
  • 79
    • 0037080629 scopus 로고    scopus 로고
    • IL-7Rα and E47: Independent pathways required for development of multipotent lymphoid progenitors
    • Kee BL, Bain G, Murre C. 2002. IL-7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors. EMBO J. 21:103-13
    • (2002) EMBO J. , vol.21 , pp. 103-113
    • Kee, B.L.1    Bain, G.2    Murre, C.3
  • 80
    • 0033871151 scopus 로고    scopus 로고
    • E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells
    • Romanow WJ, Langerak AW, Goebel P, Wolvers-Tettero ILM, van Dongen JJM, et al. 2000. E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. Mol. Cell 5:343-53
    • (2000) Mol. Cell , vol.5 , pp. 343-353
    • Romanow, W.J.1    Langerak, A.W.2    Goebel, P.3    Wolvers-Tettero, I.L.M.4    Van Dongen, J.J.M.5
  • 81
    • 0035801454 scopus 로고    scopus 로고
    • Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells
    • Goebel P, Janney N, Valenzuela JR, Romanow WJ, Murre C, Feeney AJ. 2001. Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells. J. Exp. Med. 194:645-56
    • (2001) J. Exp. Med. , vol.194 , pp. 645-656
    • Goebel, P.1    Janney, N.2    Valenzuela, J.R.3    Romanow, W.J.4    Murre, C.5    Feeney, A.J.6
  • 82
    • 0027192988 scopus 로고
    • V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer
    • Serwe M, Sablitzky F. 1993. V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer. EMBO J. 12:2321-27
    • (1993) EMBO J. , vol.12 , pp. 2321-2327
    • Serwe, M.1    Sablitzky, F.2
  • 84
    • 0033166656 scopus 로고    scopus 로고
    • A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex
    • Massari ME, Grant PA, Pray-Grant MG, Berger SL, Workman JL, Murre C. 1999. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol. Cell. 4:63-73
    • (1999) Mol. Cell. , vol.4 , pp. 63-73
    • Massari, M.E.1    Grant, P.A.2    Pray-Grant, M.G.3    Berger, S.L.4    Workman, J.L.5    Murre, C.6
  • 85
    • 0036644320 scopus 로고    scopus 로고
    • Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression
    • Smith EM, Gisler R, Sigvardsson M. 2002. Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression. J. Immunol. 169:261-70
    • (2002) J. Immunol. , vol.169 , pp. 261-270
    • Smith, E.M.1    Gisler, R.2    Sigvardsson, M.3
  • 86
    • 0026698147 scopus 로고
    • Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis
    • Adams B, Dörfler P, Aguzzi A, Kozmik Z, Urbánek P, et al. 1992. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1589-607
    • (1992) Genes Dev. , vol.6 , pp. 1589-1607
    • Adams, B.1    Dörfler, P.2    Aguzzi, A.3    Kozmik, Z.4    Urbánek, P.5
  • 87
    • 0027997502 scopus 로고
    • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
    • Urbánek P, Wang Z-Q, Fetka I, Wagner EF, Busslinger M. 1994. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79:901-12
    • (1994) Cell , vol.79 , pp. 901-912
    • Urbánek, P.1    Wang, Z.-Q.2    Fetka, I.3    Wagner, E.F.4    Busslinger, M.5
  • 88
    • 0031038031 scopus 로고    scopus 로고
    • Essential functions of Pax5 (BSAP) in pro-B cell development: Difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus
    • Nutt SL, Urbánek P, Rolink A, Busslinger M. 1997. Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. Genes Dev. 11:476-91
    • (1997) Genes Dev. , vol.11 , pp. 476-491
    • Nutt, S.L.1    Urbánek, P.2    Rolink, A.3    Busslinger, M.4
  • 89
    • 0033533891 scopus 로고    scopus 로고
    • Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
    • Nutt SL, Heavey B, Rolink AG, Busslinger M. 1999. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401:556-62
    • (1999) Nature , vol.401 , pp. 556-562
    • Nutt, S.L.1    Heavey, B.2    Rolink, A.G.3    Busslinger, M.4
  • 90
    • 0033533822 scopus 로고    scopus 로고
    • Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors
    • Rolink AG, Nutt SL, Melchers F, Busslinger M. 1999. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors. Nature 401:603-6
    • (1999) Nature , vol.401 , pp. 603-606
    • Rolink, A.G.1    Nutt, S.L.2    Melchers, F.3    Busslinger, M.4
  • 91
    • 0037079696 scopus 로고    scopus 로고
    • Multiple hematopoietic cell lineages develop in vivo from transplanted Pax5-deficient pre-B I-cell clones
    • Schaniel C, Bruno L, Melchers F, Rolink AG. 2002. Multiple hematopoietic cell lineages develop in vivo from transplanted Pax5-deficient pre-B I-cell clones. Blood 99:472-78
    • (2002) Blood , vol.99 , pp. 472-478
    • Schaniel, C.1    Bruno, L.2    Melchers, F.3    Rolink, A.G.4
  • 92
    • 0037089220 scopus 로고    scopus 로고
    • Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones
    • Schaniel C, Gottar M, Roosnek E, Melchers F, Rolink AG. 2002. Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones. Blood 99:2760-66
    • (2002) Blood , vol.99 , pp. 2760-2766
    • Schaniel, C.1    Gottar, M.2    Roosnek, E.3    Melchers, F.4    Rolink, A.G.5
  • 93
    • 0042025062 scopus 로고    scopus 로고
    • Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPα and GATA factors
    • Heavey B, Charalambous C, Cobaleda C, Busslinger M. 2003. Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPα and GATA factors. EMBO J. 22:3887-97
    • (2003) EMBO J. , vol.22 , pp. 3887-3897
    • Heavey, B.1    Charalambous, C.2    Cobaleda, C.3    Busslinger, M.4
  • 94
    • 0034959755 scopus 로고    scopus 로고
    • Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis
    • Horcher M, Souabni A, Busslinger M. 2001. Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. Immunity 14:779-90
    • (2001) Immunity , vol.14 , pp. 779-790
    • Horcher, M.1    Souabni, A.2    Busslinger, M.3
  • 95
    • 0037025198 scopus 로고    scopus 로고
    • Reversion of B cell commitment upon loss of Pax5 expression
    • Mikkola I, Heavey B, Horcher M, Busslinger M. 2002. Reversion of B cell commitment upon loss of Pax5 expression. Science 297:110-13
    • (2002) Science , vol.297 , pp. 110-113
    • Mikkola, I.1    Heavey, B.2    Horcher, M.3    Busslinger, M.4
  • 96
    • 0030954167 scopus 로고    scopus 로고
    • Multilineage gene expression precedes commitment in the hematopoietic system
    • Hu M, Krause D, Greaves M, Sharkis S, Dexter M, et al. 1997. Multilineage gene expression precedes commitment in the hematopoietic system. Genes Dev. 11:774-85
    • (1997) Genes Dev. , vol.11 , pp. 774-785
    • Hu, M.1    Krause, D.2    Greaves, M.3    Sharkis, S.4    Dexter, M.5
  • 97
    • 0032522538 scopus 로고    scopus 로고
    • Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments
    • Nutt SL, Morrison AM, Dörfler P, Rolink A, Busslinger M. 1998. Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J. 17:2319-33
    • (1998) EMBO J. , vol.17 , pp. 2319-2333
    • Nutt, S.L.1    Morrison, A.M.2    Dörfler, P.3    Rolink, A.4    Busslinger, M.5
  • 98
    • 0036906546 scopus 로고    scopus 로고
    • Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1
    • Souabni A, Cobaleda C, Schebesta M, Busslinger M. 2002. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 17:781-93
    • (2002) Immunity , vol.17 , pp. 781-793
    • Souabni, A.1    Cobaleda, C.2    Schebesta, M.3    Busslinger, M.4
  • 99
    • 0029833870 scopus 로고    scopus 로고
    • Pax-5 (BSAP) recruits Ets protooncogene family proteins to form functional ternary complexes on a B cell-specific promoter
    • Fitzsimmons D, Hodsdon W, Wheat W, Maira S-M, Wasylyk B, Hagman J. 1996. Pax-5 (BSAP) recruits Ets protooncogene family proteins to form functional ternary complexes on a B cell-specific promoter. Genes Dev. 10:2198-211
    • (1996) Genes Dev. , vol.10 , pp. 2198-2211
    • Fitzsimmons, D.1    Hodsdon, W.2    Wheat, W.3    Maira, S.-M.4    Wasylyk, B.5    Hagman, J.6
  • 100
    • 0026710736 scopus 로고
    • The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP
    • Kozmik Z, Wang S, Dörfler P, Adams B, Busslinger M. 1992. The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP. Mol. Cell. Biol. 12:2662-72
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2662-2672
    • Kozmik, Z.1    Wang, S.2    Dörfler, P.3    Adams, B.4    Busslinger, M.5
  • 101
    • 0036798665 scopus 로고    scopus 로고
    • Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene
    • Schebesta M, Pfeffer PL, Busslinger M. 2002. Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. Immunity 17:473-85
    • (2002) Immunity , vol.17 , pp. 473-485
    • Schebesta, M.1    Pfeffer, P.L.2    Busslinger, M.3
  • 102
    • 0037805640 scopus 로고    scopus 로고
    • Distinct signaling requirements for Dμ selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression of B cell progenitors
    • Hayashi K, Yamamoto M, Nojima T, Goitsuka R, Kitamura D. 2003. Distinct signaling requirements for Dμ selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression of B cell progenitors. Immunity 18:825-36
    • (2003) Immunity , vol.18 , pp. 825-836
    • Hayashi, K.1    Yamamoto, M.2    Nojima, T.3    Goitsuka, R.4    Kitamura, D.5
  • 104
    • 0343183096 scopus 로고    scopus 로고
    • Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family
    • Eberhard D, Jiménez G, Heavey B, Busslinger M. 2000. Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. EMBO J. 19:2292-303
    • (2000) EMBO J. , vol.19 , pp. 2292-2303
    • Eberhard, D.1    Jiménez, G.2    Heavey, B.3    Busslinger, M.4
  • 105
    • 16544393313 scopus 로고    scopus 로고
    • Co-recruitment of the Grg4 represser by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes
    • In press
    • Linderson Y, Eberhard D, Malin S, Johansson A, Busslinger M, Pettersson S. 2003. Co-recruitment of the Grg4 represser by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep. In press
    • (2003) EMBO Rep.
    • Linderson, Y.1    Eberhard, D.2    Malin, S.3    Johansson, A.4    Busslinger, M.5    Pettersson, S.6
  • 106
    • 0035697276 scopus 로고    scopus 로고
    • Structural studies of Ets-1/Pax5 complex formation on DNA
    • Garvie CW, Hagman J, Wolberger C. 2001. Structural studies of Ets-1/Pax5 complex formation on DNA. Mol. Cell 8:1267-76
    • (2001) Mol. Cell , vol.8 , pp. 1267-1276
    • Garvie, C.W.1    Hagman, J.2    Wolberger, C.3
  • 107
    • 0033602163 scopus 로고    scopus 로고
    • Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
    • Yokota Y, Mansouri A, Mori S, Sugawara S, Adachi S, et al. 1999. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397:702-6
    • (1999) Nature , vol.397 , pp. 702-706
    • Yokota, Y.1    Mansouri, A.2    Mori, S.3    Sugawara, S.4    Adachi, S.5
  • 109
    • 0037386339 scopus 로고    scopus 로고
    • Transcriptional profiling identifies Id2 function in dendritic cell development
    • Hacker C, Kirsch RD, Ju X-S, Hieronymus T, Gust TC, et al. 2003. Transcriptional profiling identifies Id2 function in dendritic cell development. Nat. Immunol. 4:380-86
    • (2003) Nat. Immunol. , vol.4 , pp. 380-386
    • Hacker, C.1    Kirsch, R.D.2    Ju, X.-S.3    Hieronymus, T.4    Gust, T.C.5
  • 111
    • 0032878286 scopus 로고    scopus 로고
    • Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3
    • Jaleco AC, Stegmann APA, Heemskerk MHM, Couwenberg F, Bakker AQ, et al. 1999. Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3. Blood 94:2631-46
    • (1999) Blood , vol.94 , pp. 2631-2646
    • Jaleco, A.C.1    Stegmann, A.P.A.2    Heemskerk, M.H.M.3    Couwenberg, F.4    Bakker, A.Q.5
  • 113
    • 0036533339 scopus 로고    scopus 로고
    • Deciphering the role of Notch signaling in lymphopoiesis
    • Izon DJ, Punt JA, Pear WS. 2002. Deciphering the role of Notch signaling in lymphopoiesis. Curr. Opin. Immunol. 14:192-99
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 192-199
    • Izon, D.J.1    Punt, J.A.2    Pear, W.S.3
  • 114
    • 20244389684 scopus 로고    scopus 로고
    • Notch1 expression in early lymphopoiesis influences B versus T lineage determination
    • Pui JC, Allman D, Xu L, DeRocco S, Karnell FG, et al. 1999. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11:299-308
    • (1999) Immunity , vol.11 , pp. 299-308
    • Pui, J.C.1    Allman, D.2    Xu, L.3    DeRocco, S.4    Karnell, F.G.5
  • 115
    • 0035476891 scopus 로고    scopus 로고
    • Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
    • Jaleco AC, Neves H, Hooijberg E, Gameiro P, Clode N, et al. 2001. Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. J. Exp. Med. 194:991-1001
    • (2001) J. Exp. Med. , vol.194 , pp. 991-1001
    • Jaleco, A.C.1    Neves, H.2    Hooijberg, E.3    Gameiro, P.4    Clode, N.5
  • 116
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by Delta-like-1 in vitro
    • Schmitt TM, Zúñiga-Pflücker JC. 2002. Induction of T cell development from hematopoietic progenitor cells by Delta-like-1 in vitro. Immunity 17:749-56
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zúñiga-Pflücker, J.C.2
  • 117
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • Radtke F, Wilson A, Stark G, Bauer M, van Meerwijk J, et al. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10:547-58
    • (1999) Immunity , vol.10 , pp. 547-558
    • Radtke, F.1    Wilson, A.2    Stark, G.3    Bauer, M.4    Van Meerwijk, J.5
  • 118
    • 0035477668 scopus 로고    scopus 로고
    • Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
    • Wilson A, MacDonald HR, Radtke F. 2001. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J. Exp. Med. 194:1003-12
    • (2001) J. Exp. Med. , vol.194 , pp. 1003-1012
    • Wilson, A.1    MacDonald, H.R.2    Radtke, F.3
  • 119
    • 0031923281 scopus 로고    scopus 로고
    • Notch inhibition of E47 supports the existence of a novel signaling pathway
    • Ordentlich P, Lin A, Shen C-P, Blaumueller C, Matsuno K, et al. 1998. Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell. Biol. 18:2230-39
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2230-2239
    • Ordentlich, P.1    Lin, A.2    Shen, C.-P.3    Blaumueller, C.4    Matsuno, K.5
  • 120
    • 0038819130 scopus 로고    scopus 로고
    • Pax5 determines B- versus T-cell fate and does not block early myeloid-lineage development
    • Cotta CV, Zhang Z, Kim H-G, Klug CA. 2003. Pax5 determines B- versus T-cell fate and does not block early myeloid-lineage development. Blood 101:4342-46
    • (2003) Blood , vol.101 , pp. 4342-4346
    • Cotta, C.V.1    Zhang, Z.2    Kim, H.-G.3    Klug, C.A.4
  • 123
    • 0033711624 scopus 로고    scopus 로고
    • Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
    • Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, et al. 2000. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 13:15-24
    • (2000) Immunity , vol.13 , pp. 15-24
    • Reya, T.1    O'Riordan, M.2    Okamura, R.3    Devaney, E.4    Willert, K.5
  • 124
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, et al. 2003. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423:409-14
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3    Domen, J.4    Scherer, D.C.5
  • 125
    • 0027222102 scopus 로고
    • Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes
    • van de Wetering M, Oosterwegel M, van Norren K, Clevers H. 1993. Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J. 12:3847-54
    • (1993) EMBO J. , vol.12 , pp. 3847-3854
    • Van De Wetering, M.1    Oosterwegel, M.2    Van Norren, K.3    Clevers, H.4
  • 126
    • 15844362094 scopus 로고    scopus 로고
    • Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4
    • Schilham MW, Oosterwegel MA, Moerer P, Ya J, de Boer PAJ, et al. 1996. Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature 380:711-14
    • (1996) Nature , vol.380 , pp. 711-714
    • Schilham, M.W.1    Oosterwegel, M.A.2    Moerer, P.3    Ya, J.4    De Boer, P.A.J.5
  • 127
    • 0035838988 scopus 로고    scopus 로고
    • Cytokine-specific transcriptional regulation through an IL-5Rα interacting protein
    • Geijsen N, Uings U, Pals C, Armstrong J, McKinnon M, et al. 2001. Cytokine-specific transcriptional regulation through an IL-5Rα interacting protein. Science 293:1136-38
    • (2001) Science , vol.293 , pp. 1136-1138
    • Geijsen, N.1    Uings, U.2    Pals, C.3    Armstrong, J.4    McKinnon, M.5
  • 128
    • 16044375187 scopus 로고    scopus 로고
    • Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5Rα-deficient mice
    • Yoshida T, Ikuta K, Sugaya H, Maki K, Takagi M, et al. 1996. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5Rα-deficient mice. Immunity 4:483-94
    • (1996) Immunity , vol.4 , pp. 483-494
    • Yoshida, T.1    Ikuta, K.2    Sugaya, H.3    Maki, K.4    Takagi, M.5
  • 130
    • 0033525063 scopus 로고    scopus 로고
    • The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif
    • Lin D, Gish GD, Songyang Z, Pawson T. 1999. The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif. J. Biol. Chem. 274:3726-33
    • (1999) J. Biol. Chem. , vol.274 , pp. 3726-3733
    • Lin, D.1    Gish, G.D.2    Songyang, Z.3    Pawson, T.4
  • 131
    • 0038506030 scopus 로고    scopus 로고
    • IRF-4/8 orchestrate the pre-B-to-B transition in lymphocyte development
    • Lu R, Medina KL, Lancki DW, Singh H. 2003. IRF-4/8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 17:1703-8
    • (2003) Genes Dev. , vol.17 , pp. 1703-1708
    • Lu, R.1    Medina, K.L.2    Lancki, D.W.3    Singh, H.4
  • 132
    • 0036530202 scopus 로고    scopus 로고
    • Differential surrogate light chain expression governs B-cell differentiation
    • Wang YH, Stephan RP, Scheffold A, Kunkel D, Karasuyama H, et al. 2002. Differential surrogate light chain expression governs B-cell differentiation. Blood 99:2459-67
    • (2002) Blood , vol.99 , pp. 2459-2467
    • Wang, Y.H.1    Stephan, R.P.2    Scheffold, A.3    Kunkel, D.4    Karasuyama, H.5
  • 133
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. 2001. Translating the histone code. Science 293:1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 134
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • Turner BM. 2002. Cellular memory and the histone code. Cell 111:285-91
    • (2002) Cell , vol.111 , pp. 285-291
    • Turner, B.M.1
  • 136
    • 0037089626 scopus 로고    scopus 로고
    • SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
    • Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ III. 2002. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16:919-32
    • (2002) Genes Dev. , vol.16 , pp. 919-932
    • Schultz, D.C.1    Ayyanathan, K.2    Negorev, D.3    Maul, G.G.4    Rauscher III, F.J.5
  • 137
    • 0037625160 scopus 로고    scopus 로고
    • Gene segment selection in V(D)J recombination: Accessibility and beyond
    • Krangel MS. 2003. Gene segment selection in V(D)J recombination: accessibility and beyond. Nat. Immunol. 4:624-30
    • (2003) Nat. Immunol. , vol.4 , pp. 624-630
    • Krangel, M.S.1
  • 138
    • 0034695501 scopus 로고    scopus 로고
    • A role for histone acetylation in the developmental regulation of V(D)J recombination
    • McMurry MT, Krangel MS. 2000. A role for histone acetylation in the developmental regulation of V(D)J recombination. Science 287:495-98
    • (2000) Science , vol.287 , pp. 495-498
    • McMurry, M.T.1    Krangel, M.S.2
  • 139
    • 0035890244 scopus 로고    scopus 로고
    • Stepwise activation of the immunoglobulin μ heavy chain gene locus
    • Chowdhury D, Sen R. 2001. Stepwise activation of the immunoglobulin μ heavy chain gene locus. EMBO J. 20:6394-403
    • (2001) EMBO J. , vol.20 , pp. 6394-6403
    • Chowdhury, D.1    Sen, R.2
  • 141
    • 0037332014 scopus 로고    scopus 로고
    • Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements
    • Chowdhury D, Sen R. 2003. Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements. Immunity 18:229-41
    • (2003) Immunity , vol.18 , pp. 229-241
    • Chowdhury, D.1    Sen, R.2
  • 142
    • 0037320925 scopus 로고    scopus 로고
    • Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
    • Su IH, Basavaraj A, Krutchinsky AN, Hobert O, Ullrich A, et al. 2003. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat. Immunol. 4:124-31
    • (2003) Nat. Immunol. , vol.4 , pp. 124-131
    • Su, I.H.1    Basavaraj, A.2    Krutchinsky, A.N.3    Hobert, O.4    Ullrich, A.5
  • 143
    • 0037963483 scopus 로고    scopus 로고
    • The establishment and maintenance of lymphocyte identity through gene silencing
    • Smale ST. 2003. The establishment and maintenance of lymphocyte identity through gene silencing. Nat. Immunol. 4:607-15
    • (2003) Nat. Immunol. , vol.4 , pp. 607-615
    • Smale, S.T.1
  • 144
    • 0037023361 scopus 로고    scopus 로고
    • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
    • Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, et al. 2002. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296:158-62
    • (2002) Science , vol.296 , pp. 158-162
    • Kosak, S.T.1    Skok, J.A.2    Medina, K.L.3    Riblet, R.4    Le Beau, M.M.5
  • 145
    • 0033083793 scopus 로고    scopus 로고
    • Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
    • Brown KE, Baxter J, Graf D, Merkenschlager M, Fisher AG. 1999. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell 3:207-17
    • (1999) Mol. Cell , vol.3 , pp. 207-217
    • Brown, K.E.1    Baxter, J.2    Graf, D.3    Merkenschlager, M.4    Fisher, A.G.5
  • 147
    • 0033103013 scopus 로고    scopus 로고
    • Ikaros sets thresholds for T cell activation and regulates chromosome propagation
    • Avitahl N, Winandy S, Friedrich C, Jones B, Ge Y, Georgopoulos K. 1999. Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity 10:333-43
    • (1999) Immunity , vol.10 , pp. 333-343
    • Avitahl, N.1    Winandy, S.2    Friedrich, C.3    Jones, B.4    Ge, Y.5    Georgopoulos, K.6
  • 149
    • 0033805828 scopus 로고    scopus 로고
    • An Ikaros-containing chromatin-remodeling complex in adult-type erythroid cells
    • O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, et al. 2000. An Ikaros-containing chromatin-remodeling complex in adult-type erythroid cells. Mol Cell Biol. 20:7572-82
    • (2000) Mol Cell Biol. , vol.20 , pp. 7572-7582
    • O'Neill, D.W.1    Schoetz, S.S.2    Lopez, R.A.3    Castle, M.4    Rabinowitz, L.5
  • 150
    • 0035281938 scopus 로고    scopus 로고
    • Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes
    • Sif S, Saurin AJ, Imbalzano AN, Kingston RE. 2001. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. Genes Dev. 15:603-18
    • (2001) Genes Dev. , vol.15 , pp. 603-618
    • Sif, S.1    Saurin, A.J.2    Imbalzano, A.N.3    Kingston, R.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.