Thiazolidinediones (PPARγ ligands) increase IRS-1, UCP-2 and C/EBPα expression, but not transdifferentiation, in L6 muscle cells

Diabetologia

Volumn 46, Issue 1, 2003, Pages 48-52

  Hammarstedt, A ^a   Smith, U ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

C EBP ; Gene transcription; Insulin signalling; IRS; PPAR; Thiazolidinediones; UCP2

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; BIOLOGICAL MARKER; CCAAT ENHANCER BINDING PROTEIN ALPHA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROTEIN KINASE B; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; TRANSCRIPTION FACTOR AP 2; UNCOUPLING PROTEIN 2; CARRIER PROTEIN; CCAAT ENHANCER BINDING PROTEIN; CELL RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; ION CHANNEL; LIGAND; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; PHOSPHOPROTEIN; PROTEIN; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; GENE ACTIVATION; HUMAN; MUSCLE CELL; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CYTOLOGY; METABOLISM; TIME;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CELL LINE; ION CHANNELS; LIGANDS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PROTEINS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIAZOLES; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 0037285962     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-1002-7     Document Type: Article

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