-
2
-
-
23744503085
-
Aurora kinases: Shining lights on the therapeutic horizon?
-
Andrews PD. Aurora kinases: shining lights on the therapeutic horizon? Oncogene 2005; 24:5005-15.
-
(2005)
Oncogene
, vol.24
, pp. 5005-5015
-
-
Andrews, P.D.1
-
3
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
-
Pugacheva EN and Golemis EA. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol 2005; 7:937-46.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
4
-
-
0036468420
-
Centrosome composition and microtubule anchoring mechanisms
-
Bornens M. Centrosome composition and microtubule anchoring mechanisms. Curr Opin Cell Biol 2002; 14:25-34.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 25-34
-
-
Bornens, M.1
-
5
-
-
0037134898
-
The centrosome cycle
-
Meraldi P and Nigg E. A. The centrosome cycle. FEBS Lett 2002; 521:9-13.
-
(2002)
FEBS Lett
, vol.521
, pp. 9-13
-
-
Meraldi, P.1
Nigg, E.A.2
-
6
-
-
0034565442
-
Centrosome maturation
-
Palazzo RE, Vogel JM, Schnackenberg BJ, Hull DR and Wu X. Centrosome maturation. Curr Top Dev Biol 2000; 49:449-70.
-
(2000)
Curr Top Dev Biol
, vol.49
, pp. 449-470
-
-
Palazzo, R.E.1
Vogel, J.M.2
Schnackenberg, B.J.3
Hull, D.R.4
Wu, X.5
-
7
-
-
0035478337
-
The centrosome in vertebrates: More than a microtubule-organizing center
-
Rieder CL, Faruki S and Khodjakov A. The centrosome in vertebrates: more than a microtubule-organizing center. Trends Cell Biol 2001; 11:413-9.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 413-419
-
-
Rieder, C.L.1
Faruki, S.2
Khodjakov, A.3
-
11
-
-
0035945614
-
Adherens junctions inhibit asymmetric division in the Drosophila epithelium
-
Lu B, Roegiers F, Jan LY and Jan YN. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 2001; 409:522-5.
-
(2001)
Nature
, vol.409
, pp. 522-525
-
-
Lu, B.1
Roegiers, F.2
Jan, L.Y.3
Jan, Y.N.4
-
12
-
-
0035807797
-
Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila
-
USA
-
Roegiers F, Younger-Shepherd S, Jan LY and Jan YN. Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila. Proc Natl Acad Sci USA 2001; 98:14469-74.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 14469-14474
-
-
Roegiers, F.1
Younger-Shepherd, S.2
Jan, L.Y.3
Jan, Y.N.4
-
13
-
-
0141483737
-
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome
-
Yamashita YM, Jones DL and Fuller MT. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 2003; 301:1547-50.
-
(2003)
Science
, vol.301
, pp. 1547-1550
-
-
Yamashita, Y.M.1
Jones, D.L.2
Fuller, M.T.3
-
14
-
-
0034789121
-
Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
-
McCartney BM, McEwen DG, Grevengoed E, Maddox P, Bejsovec A and Peifer M. Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nat Cell Biol 2001; 3:933-8.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 933-938
-
-
McCartney, B.M.1
McEwen, D.G.2
Grevengoed, E.3
Maddox, P.4
Bejsovec, A.5
Peifer, M.6
-
15
-
-
1542374119
-
Parsing the polarity code
-
Macara, I. G. Parsing the polarity code. Nat Rev Mol Cell Biol 2004; 5:220-31.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 220-231
-
-
Macara, I.G.1
-
16
-
-
0346155807
-
Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote
-
Schneider SQ and Bowerman B. Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote. Annu Rev Genet 2003; 37:221-49.
-
(2003)
Annu Rev Genet
, vol.37
, pp. 221-249
-
-
Schneider, S.Q.1
Bowerman, B.2
-
17
-
-
0032567757
-
Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast
-
Miller RK and Rose MD. Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast. J Cell Biol 1998; 140:377-90.
-
(1998)
J Cell Biol
, vol.140
, pp. 377-390
-
-
Miller, R.K.1
Rose, M.D.2
-
18
-
-
0035312697
-
Control of spindle polarity and orientation in Saccharomyces cerevisiae
-
Segal M and Bloom K. Control of spindle polarity and orientation in Saccharomyces cerevisiae. Trends Cell Biol 2001; 11:160-6.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 160-166
-
-
Segal, M.1
Bloom, K.2
-
19
-
-
24644494270
-
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
-
Lechler T and Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005; 437:275-80.
-
(2005)
Nature
, vol.437
, pp. 275-280
-
-
Lechler, T.1
Fuchs, E.2
-
20
-
-
23644449576
-
Centrosome localization determines neuronal polarity
-
de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F and Dotti CG. Centrosome localization determines neuronal polarity. Nature 2005; 436:704-8.
-
(2005)
Nature
, vol.436
, pp. 704-708
-
-
De Anda, F.C.1
Pollarolo, G.2
Da Silva, J.S.3
Camoletto, P.G.4
Feiguin, F.5
Dotti, C.G.6
-
21
-
-
29244456404
-
Caught Nek-ing: Cilia and centrioles
-
Quarmby LM and Mahjoub MR. Caught Nek-ing: cilia and centrioles. J Cell Sci 2005; 118:5161-9.
-
(2005)
J Cell Sci
, vol.118
, pp. 5161-5169
-
-
Quarmby, L.M.1
Mahjoub, M.R.2
-
22
-
-
27144460671
-
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
-
Ross AJ, May-Simera H, Eichers ER, Kai M, Hill J, Jagger DJ, Leitch CC, Chapple JP, Munro PM, Fisher S, Tan PL, Phillips HM, Leroux MR, Henderson DJ, Murdoch JN, Copp AJ, Eliot MM, Lupski JR, Kemp DT, Dollfus H, Tada M, Katsanis N, Forge A and Beales PL. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet 2005; 37:1135-40.
-
(2005)
Nat Genet
, vol.37
, pp. 1135-1140
-
-
Ross, A.J.1
May-Simera, H.2
Eichers, E.R.3
Kai, M.4
Hill, J.5
Jagger, D.J.6
Leitch, C.C.7
Chapple, J.P.8
Munro, P.M.9
Fisher, S.10
Tan, P.L.11
Phillips, H.M.12
Leroux, M.R.13
Henderson, D.J.14
Murdoch, J.N.15
Copp, A.J.16
Eliot, M.M.17
Lupski, J.R.18
Kemp, D.T.19
Dollfus, H.20
Tada, M.21
Katsanis, N.22
Forge, A.23
Beales, P.L.24
more..
-
23
-
-
20944435539
-
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
-
Simons M, Gloy J, Ganner A, Bullerkotte A, Bashkurov M, Kronig C, Schermer B, Benzing T, Cabello OA, Jenny A, Mlodzik M, Polok B, Driever W, Obara T and Walz G. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005; 37:537-43.
-
(2005)
Nat Genet
, vol.37
, pp. 537-543
-
-
Simons, M.1
Gloy, J.2
Ganner, A.3
Bullerkotte, A.4
Bashkurov, M.5
Kronig, C.6
Schermer, B.7
Benzing, T.8
Cabello, O.A.9
Jenny, A.10
Mlodzik, M.11
Polok, B.12
Driever, W.13
Obara, T.14
Walz, G.15
-
24
-
-
27144529532
-
PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts
-
Schneider L, Clement CA, Teilmann SC, Pazour GJ, Hoffmann EK, Satir P and Christensen ST. PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts. Curr Biol 2005; 15:1861-6.
-
(2005)
Curr Biol
, vol.15
, pp. 1861-1866
-
-
Schneider, L.1
Clement, C.A.2
Teilmann, S.C.3
Pazour, G.J.4
Hoffmann, E.K.5
Satir, P.6
Christensen, S.T.7
-
25
-
-
22344445826
-
Cilia and the cell cycle?
-
Quarmby LM and Parker JD. Cilia and the cell cycle? J Cell Biol 2005; 169:707-10.
-
(2005)
J Cell Biol
, vol.169
, pp. 707-710
-
-
Quarmby, L.M.1
Parker, J.D.2
-
26
-
-
0037048312
-
The Nek2 protein kinase: A novel regulator of centrosome structure
-
Fry AM. The Nek2 protein kinase: a novel regulator of centrosome structure. Oncogene 2002; 21:6184-94.
-
(2002)
Oncogene
, vol.21
, pp. 6184-6194
-
-
Fry, A.M.1
-
27
-
-
0030928756
-
Centrosome positioning and directionality of cell movements
-
USA
-
Ueda M, Graf R, MacWilliams HK, Schliwa M and Euteneuer U. Centrosome positioning and directionality of cell movements. Proc Natl Acad Sci USA 1997; 94:9674-8.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 9674-9678
-
-
Ueda, M.1
Graf, R.2
MacWilliams, H.K.3
Schliwa, M.4
Euteneuer, U.5
-
28
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes CD and Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 1999; 144:1235-44.
-
(1999)
J Cell Biol
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
29
-
-
0034749519
-
Centrosome behavior in motile HGF-treated PtK2 cells expressing GFP-gamma tubulin
-
Danowski BA, Khodjakov A and Wadsworth P. Centrosome behavior in motile HGF-treated PtK2 cells expressing GFP-gamma tubulin. Cell Motil Cytoskeleton 2001; 50:59-68.
-
(2001)
Cell Motil Cytoskeleton
, vol.50
, pp. 59-68
-
-
Danowski, B.A.1
Khodjakov, A.2
Wadsworth, P.3
-
30
-
-
0037049545
-
Microtubule release from the centrosome in migrating cells
-
Abal M, Piel M, Bouckson-Castaing V, Mogensen M, Sibarita JB and Bornens M. Microtubule release from the centrosome in migrating cells. J Cell Biol 2002; 159:731-7.
-
(2002)
J Cell Biol
, vol.159
, pp. 731-737
-
-
Abal, M.1
Piel, M.2
Bouckson-Castaing, V.3
Mogensen, M.4
Sibarita, J.B.5
Bornens, M.6
-
31
-
-
24944577909
-
Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization
-
Etienne-Manneville S, Manneville JB, Nicholls S, Ferenczi MA and Hall A. Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization. J Cell Biol 2005; 170:895-901.
-
(2005)
J Cell Biol
, vol.170
, pp. 895-901
-
-
Etienne-Manneville, S.1
Manneville, J.B.2
Nicholls, S.3
Ferenczi, M.A.4
Hall, A.5
-
32
-
-
21644460380
-
Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways
-
Cau J and Hall A. Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways. J Cell Sci 2005; 118:2579-87.
-
(2005)
J Cell Sci
, vol.118
, pp. 2579-2587
-
-
Cau, J.1
Hall, A.2
-
33
-
-
0037434790
-
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
-
Etienne-Manneville S and Hall A. Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 2003; 421:753-6.
-
(2003)
Nature
, vol.421
, pp. 753-756
-
-
Etienne-Manneville, S.1
Hall, A.2
-
34
-
-
0035985157
-
Centrosome reorientation in wound-edge cells is cell type specific
-
Yvon AM, Walker JW, Danowski B, Fagerstrom C, Khodjakov A and Wadsworth P. Centrosome reorientation in wound-edge cells is cell type specific. Mol Biol Cell 2002; 13:1871-80.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1871-1880
-
-
Yvon, A.M.1
Walker, J.W.2
Danowski, B.3
Fagerstrom, C.4
Khodjakov, A.5
Wadsworth, P.6
-
35
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl P and Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003; 3:362-74.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
36
-
-
1642282882
-
Prespecification and plasticity: Shifting mechanisms of cell migration
-
Friedl P. Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol 2004; 16:14-23.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 14-23
-
-
Friedl, P.1
-
37
-
-
7444229923
-
A centrosomal localization signal in cyclin e required for Cdk2-independent S phase entry
-
Matsumoto Y and Maller JL. A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry. Science 2004; 306:885-8.
-
(2004)
Science
, vol.306
, pp. 885-888
-
-
Matsumoto, Y.1
Maller, J.L.2
-
38
-
-
0033594469
-
Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
-
Matsumoto Y, Hayashi K and Nishida E. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells. Curr Biol 1999; 9:429-32.
-
(1999)
Curr Biol
, vol.9
, pp. 429-432
-
-
Matsumoto, Y.1
Hayashi, K.2
Nishida, E.3
-
39
-
-
0033055061
-
Cyclin-dependent kinase control of centrosome duplication
-
USA
-
Lacey KR, Jackson PK and Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proc Natl Acad Sci USA 1999; 96:2817-22.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 2817-2822
-
-
Lacey, K.R.1
Jackson, P.K.2
Stearns, T.3
-
40
-
-
0032517865
-
Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells
-
Bobinnec Y, Khodjakov A, Mir LM, Rieder CL, Edde B and Bornens M. Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells. J Cell Biol 1998; 143:1575-89.
-
(1998)
J Cell Biol
, vol.143
, pp. 1575-1589
-
-
Bobinnec, Y.1
Khodjakov, A.2
Mir, L.M.3
Rieder, C.L.4
Edde, B.5
Bornens, M.6
-
41
-
-
0037048279
-
On the role of aurora-A in centrosome function
-
Dutertre S, Descamps S and Prigent C. On the role of aurora-A in centrosome function. Oncogene 2002; 21:6175-83.
-
(2002)
Oncogene
, vol.21
, pp. 6175-6183
-
-
Dutertre, S.1
Descamps, S.2
Prigent, C.3
-
42
-
-
0141429171
-
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K and Saya H. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 2003; 114:585-98.
-
(2003)
Cell
, vol.114
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
Marumoto, T.4
Zhang, D.5
Nitta, M.6
Hatakeyama, K.7
Saya, H.8
-
43
-
-
0037322744
-
Active cyclin B1-Cdk1 first appears on centrosomes in prophase
-
Jackman M, Lindon C, Nigg EA and Pines J. Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol 2003; 5:143-8.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 143-148
-
-
Jackman, M.1
Lindon, C.2
Nigg, E.A.3
Pines, J.4
-
44
-
-
0032489799
-
Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome
-
Dictenberg JB, Zimmerman W, Sparks CA, Young A, Vidair C, Zheng Y, Carrington W, Fay FS and Doxsey SJ. Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome. J Cell Biol 1998; 141:163-74.
-
(1998)
J Cell Biol
, vol.141
, pp. 163-174
-
-
Dictenberg, J.B.1
Zimmerman, W.2
Sparks, C.A.3
Young, A.4
Vidair, C.5
Zheng, Y.6
Carrington, W.7
Fay, F.S.8
Doxsey, S.J.9
-
45
-
-
0033561311
-
The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells
-
Huang J and Raff JW. The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells. EMBO J 1999; 18:2184-95.
-
(1999)
EMBO J
, vol.18
, pp. 2184-2195
-
-
Huang, J.1
Raff, J.W.2
-
46
-
-
0034597590
-
Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos
-
Wakefield JG, Huang JY and Raff JW. Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos. Curr Biol 2000; 10:1367-70.
-
(2000)
Curr Biol
, vol.10
, pp. 1367-1370
-
-
Wakefield, J.G.1
Huang, J.Y.2
Raff, J.W.3
-
47
-
-
0037166933
-
The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time
-
Raff JW, Jeffers K and Huang JY. The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time. J Cell Biol 2002; 157:1139-49.
-
(2002)
J Cell Biol
, vol.157
, pp. 1139-1149
-
-
Raff, J.W.1
Jeffers, K.2
Huang, J.Y.3
-
48
-
-
0345593387
-
Dynamic association of proteasomal machinery with the centrosome
-
Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, DeMartino GN and Thomas PJ. Dynamic association of proteasomal machinery with the centrosome. J Cell Biol 1999; 145:481-90.
-
(1999)
J Cell Biol
, vol.145
, pp. 481-490
-
-
Wigley, W.C.1
Fabunmi, R.P.2
Lee, M.G.3
Marino, C.R.4
Muallem, S.5
DeMartino, G.N.6
Thomas, P.J.7
-
49
-
-
0035936920
-
Centrosome-dependent exit of cytokinesis in animal cells
-
Piel M, Nordberg J, Euteneuer U and Bornens M. Centrosome-dependent exit of cytokinesis in animal cells. Science 2001; 291:1550-3.
-
(2001)
Science
, vol.291
, pp. 1550-1553
-
-
Piel, M.1
Nordberg, J.2
Euteneuer, U.3
Bornens, M.4
-
50
-
-
26444544501
-
Cdk1/Erk2- And plk1-dependent phosphorylation of a centrosome protein, cep55, is required for its recruitment to midbody and cytokinesis
-
Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y and Khanna KK. Cdk1/Erk2- and plk1-dependent phosphorylation of a centrosome protein, cep55, is required for its recruitment to midbody and cytokinesis. Dev Cell 2005; 9:477-88.
-
(2005)
Dev Cell
, vol.9
, pp. 477-488
-
-
Fabbro, M.1
Zhou, B.B.2
Takahashi, M.3
Sarcevic, B.4
Lal, P.5
Graham, M.E.6
Gabrielli, B.G.7
Robinson, P.J.8
Nigg, E.A.9
Ono, Y.10
Khanna, K.K.11
-
51
-
-
20344387214
-
Conditional transgenic system for mouse aurora a kinase: Degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein
-
Fukuda T, Mishina Y, Walker MP and DiAugustine RP. Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Mol Cell Biol 2005; 25:5270-81.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5270-5281
-
-
Fukuda, T.1
Mishina, Y.2
Walker, M.P.3
DiAugustine, R.P.4
-
52
-
-
0037446847
-
A novel mechanism for activation of the protein kinase Aurora A
-
Eyers PA, Erikson E, Chen LG and Mailer JL. A novel mechanism for activation of the protein kinase Aurora A. Curr Biol 2003; 13:691-7.
-
(2003)
Curr Biol
, vol.13
, pp. 691-697
-
-
Eyers, P.A.1
Erikson, E.2
Chen, L.G.3
Mailer, J.L.4
-
53
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C and Zheng Y. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 2003; 5:242-8.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 242-248
-
-
Tsai, M.Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
54
-
-
3042734502
-
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition
-
Dutertre S, Cazales M, Quaranta M, Froment C, Trabut V, Dozier C, Mirey G, Bouche JP, Theis-Febvre N, Schmitt E, Monsarrat B, Prigent C and Ducommun B. Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 2004; 117:2523-31.
-
(2004)
J Cell Sci
, vol.117
, pp. 2523-2531
-
-
Dutertre, S.1
Cazales, M.2
Quaranta, M.3
Froment, C.4
Trabut, V.5
Dozier, C.6
Mirey, G.7
Bouche, J.P.8
Theis-Febvre, N.9
Schmitt, E.10
Monsarrat, B.11
Prigent, C.12
Ducommun, B.13
-
55
-
-
0028938482
-
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
-
Glover DM, Leibowitz MH, McLean DA and Parry H. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 1995; 81:95-105.
-
(1995)
Cell
, vol.81
, pp. 95-105
-
-
Glover, D.M.1
Leibowitz, M.H.2
McLean, D.A.3
Parry, H.4
-
56
-
-
0347324949
-
Aurora-a kinase maintains the fidelity of early and late mitotic events in HeLa cells
-
Marumoto T, Honda S, Hara T, Nitta M, Hirota T, Kohmura E and Saya H. Aurora-a kinase maintains the fidelity of early and late mitotic events in HeLa cells. J Biol Chem 2003.
-
(2003)
J Biol Chem
-
-
Marumoto, T.1
Honda, S.2
Hara, T.3
Nitta, M.4
Hirota, T.5
Kohmura, E.6
Saya, H.7
-
57
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ and Plowman GD. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 1998; 17:3052-65.
-
(1998)
EMBO J
, vol.17
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
Chan, C.S.11
Novotny, M.12
Slamon, D.J.13
Plowman, G.D.14
-
58
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR and Sen S. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998; 20:189-93.
-
(1998)
Nat Genet
, vol.20
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
-
59
-
-
0037099531
-
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis
-
Goepfert TM, Adigun YE, Zhong L, Gay J, Medina D and Brinkley WR. Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. Cancer Res 2002; 62:4115-22.
-
(2002)
Cancer Res
, vol.62
, pp. 4115-4122
-
-
Goepfert, T.M.1
Adigun, Y.E.2
Zhong, L.3
Gay, J.4
Medina, D.5
Brinkley, W.R.6
-
60
-
-
0034025874
-
Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer
-
Tanner MM, Grenman S, Koul A, Johannsson O, Meltzer P, Pejovic T, Borg A and Isola JJ. Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin Cancer Res 2000; 6:1833-9.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1833-1839
-
-
Tanner, M.M.1
Grenman, S.2
Koul, A.3
Johannsson, O.4
Meltzer, P.5
Pejovic, T.6
Borg, A.7
Isola, J.J.8
-
61
-
-
0033135640
-
Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast
-
Tanaka T, Kimura M, Matsunaga K, Fukada D, Mori H and Okano Y. Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res 1999; 59:2041-4.
-
(1999)
Cancer Res
, vol.59
, pp. 2041-2044
-
-
Tanaka, T.1
Kimura, M.2
Matsunaga, K.3
Fukada, D.4
Mori, H.5
Okano, Y.6
-
62
-
-
0037084163
-
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- Cells
-
Meraldi P, Honda R and Nigg EA. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. Embo J 2002; 21:483-92.
-
(2002)
Embo J
, vol.21
, pp. 483-492
-
-
Meraldi, P.1
Honda, R.2
Nigg, E.A.3
-
63
-
-
0037586498
-
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
-
Anand S, Penrhyn-Lowe S and Venkitaraman AR. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 2003; 3:51-62.
-
(2003)
Cancer Cell
, vol.3
, pp. 51-62
-
-
Anand, S.1
Penrhyn-Lowe, S.2
Venkitaraman, A.R.3
-
64
-
-
9944220985
-
Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
-
Zhang D, Hirota T, Marumoto T, Shimizu M, Kunitoku N, Sasayama T, Arima Y, Feng L, Suzuki M, Takeya M and Saya H. Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene 2004; 23:8720-30.
-
(2004)
Oncogene
, vol.23
, pp. 8720-8730
-
-
Zhang, D.1
Hirota, T.2
Marumoto, T.3
Shimizu, M.4
Kunitoku, N.5
Sasayama, T.6
Arima, Y.7
Feng, L.8
Suzuki, M.9
Takeya, M.10
Saya, H.11
-
65
-
-
0032213515
-
Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
-
Tatsuka M, Katayama H, Ota T, Tanaka T, Odashima S, Suzuki F and Terada Y. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res 1998; 58:4811-6.
-
(1998)
Cancer Res
, vol.58
, pp. 4811-4816
-
-
Tatsuka, M.1
Katayama, H.2
Ota, T.3
Tanaka, T.4
Odashima, S.5
Suzuki, F.6
Terada, Y.7
-
66
-
-
0037386929
-
Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer
-
Gritsko TM, Coppola D, Paciga JE, Yang L, Sun M, Shelley SA, Fiorica JV, Nicosia SV and Cheng JQ. Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer. Clin Cancer Res 2003; 9:1420-6.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1420-1426
-
-
Gritsko, T.M.1
Coppola, D.2
Paciga, J.E.3
Yang, L.4
Sun, M.5
Shelley, S.A.6
Fiorica, J.V.7
Nicosia, S.V.8
Cheng, J.Q.9
-
67
-
-
20144386737
-
Chfr is required for tumor suppression and Aurora A regulation
-
Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ, Ward IM, Saya H, Fang G, van Deursen J and Chen J. Chfr is required for tumor suppression and Aurora A regulation. Nat Genet 2005; 37:401-6.
-
(2005)
Nat Genet
, vol.37
, pp. 401-406
-
-
Yu, X.1
Minter-Dykhouse, K.2
Malureanu, L.3
Zhao, W.M.4
Zhang, D.5
Merkle, C.J.6
Ward, I.M.7
Saya, H.8
Fang, G.9
Van Deursen, J.10
Chen, J.11
-
68
-
-
0037009435
-
Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function
-
Chen SS, Chang PC, Cheng YW, Tang FM and Lin YS. Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function. Embo J 2002; 21:4491-9.
-
(2002)
Embo J
, vol.21
, pp. 4491-4499
-
-
Chen, S.S.1
Chang, P.C.2
Cheng, Y.W.3
Tang, F.M.4
Lin, Y.S.5
-
69
-
-
9144251019
-
Phosphorylation by aurora kinase a induces Mdm2-mediated destabilization and inhibition of p53
-
Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA and Sen S. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 2004; 36:55-62.
-
(2004)
Nat Genet
, vol.36
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
Yuan, Z.M.4
Bondaruk, J.5
Suzuki, F.6
Fujii, S.7
Arlinghaus, R.B.8
Czerniak, B.A.9
Sen, S.10
-
70
-
-
0022403659
-
Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies
-
Zantema A, Fransen JA, Davis-Olivier A, Ramaekers FC, Vooijs GP, DeLeys B and Van der Eb AJ. Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies. Virology 1985; 142:44-58.
-
(1985)
Virology
, vol.142
, pp. 44-58
-
-
Zantema, A.1
Fransen, J.A.2
Davis-Olivier, A.3
Ramaekers, F.C.4
Vooijs, G.P.5
DeLeys, B.6
Van Der Eb, A.J.7
-
71
-
-
0029891787
-
Human Enhancer of Filamentation 1 (HEF1), a novel p130Cas-like docking protein, associates with FAK, and induces pseudohyphal growth in yeast
-
Law SF, Estojak J, Wang B, Mysliwiec T, Kruh GD and Golemis EA. Human Enhancer of Filamentation 1 (HEF1), a novel p130Cas-like docking protein, associates with FAK, and induces pseudohyphal growth in yeast. Mol. Cell. Biol. 1996; 16:3327-3337.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3327-3337
-
-
Law, S.F.1
Estojak, J.2
Wang, B.3
Mysliwiec, T.4
Kruh, G.D.5
Golemis, E.A.6
-
72
-
-
0029904694
-
Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta-1 integrin-mediated signaling in lymphocytes
-
Minegishi M, Tachibana K, Sato T, Iwata S, Nojima Y and Morimoto C. Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta-1 integrin-mediated signaling in lymphocytes. J. Exp. Med. 1996; 184:1365-1375.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1365-1375
-
-
Minegishi, M.1
Tachibana, K.2
Sato, T.3
Iwata, S.4
Nojima, Y.5
Morimoto, C.6
-
73
-
-
0029562687
-
Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn
-
Ishino M, Ohba T, Sasaki H and Sasaki T. Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 1995; 11:2331-2338.
-
(1995)
Oncogene
, vol.11
, pp. 2331-2338
-
-
Ishino, M.1
Ohba, T.2
Sasaki, H.3
Sasaki, T.4
-
74
-
-
0028915798
-
Proline-rich sequences that bind to Src homology 3 domains with individual specificities
-
USA
-
Alexandropoulos K, Cheng G and Baltimore D. Proline-rich sequences that bind to Src homology 3 domains with individual specificities. Proc. Nat. Acad. Sci. USA 1995; 92:3110-3114.
-
(1995)
Proc. Nat. Acad. Sci.
, vol.92
, pp. 3110-3114
-
-
Alexandropoulos, K.1
Cheng, G.2
Baltimore, D.3
-
75
-
-
0027990414
-
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner
-
Sakai R, Iwamatsu A, Hirano N, Ogawa S, Tanaka T, Mano H, Yazaki Y and Hirai H. A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J 1994; 13:3748-3756.
-
(1994)
EMBO J
, vol.13
, pp. 3748-3756
-
-
Sakai, R.1
Iwamatsu, A.2
Hirano, N.3
Ogawa, S.4
Tanaka, T.5
Mano, H.6
Yazaki, Y.7
Hirai, H.8
-
76
-
-
0034160011
-
Integrin signaling: A new Cas(t) of characters enters the stage
-
O'Neill GM, Fashena SJ and Golemis EA. Integrin signaling: a new Cas(t) of characters enters the stage. Trends Cell Biol. 2000; 10:111-119.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 111-119
-
-
O'Neill, G.M.1
Fashena, S.J.2
Golemis, E.A.3
-
77
-
-
0035474419
-
Functions of the adapter protein Cas: Signal convergence and the determination of cellular responses
-
Bouton AH, Riggins R B and Bruce-Staskal PJ. Functions of the adapter protein Cas: signal convergence and the determination of cellular responses. Oncogene 2001; 20:6448-58.
-
(2001)
Oncogene
, vol.20
, pp. 6448-6458
-
-
Bouton, A.H.1
Riggins, R.B.2
Bruce-Staskal, P.J.3
-
78
-
-
0029766101
-
Coordinate activation of c-Src by SH3- And SH2-binding sites on a novel, p130Cas-related protein, Sin
-
Alexandropoulos K and Baltimore D. Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel, p130Cas-related protein, Sin. Genes Dev. 1996; 10:1341-1355.
-
(1996)
Genes Dev
, vol.10
, pp. 1341-1355
-
-
Alexandropoulos, K.1
Baltimore, D.2
-
79
-
-
0033860096
-
Regulation of c-SRC activity and function by the adapter protein CAS
-
Burnham MR, Bruce-Staskal PJ, Harte MT, Weidow CL, Ma A, Weed SA and Bouton AH. Regulation of c-SRC activity and function by the adapter protein CAS. Mol Cell Biol 2000; 20:5865-78.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5865-5878
-
-
Burnham, M.R.1
Bruce-Staskal, P.J.2
Harte, M.T.3
Weidow, C.L.4
Ma, A.5
Weed, S.A.6
Bouton, A.H.7
-
80
-
-
21344443681
-
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells
-
Brabek J, Constancio SS, Siesser PF, Shin NY, Pozzi A and Hanks SK. Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Mol Cancer Res 2005; 3:307-15.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 307-315
-
-
Brabek, J.1
Constancio, S.S.2
Siesser, P.F.3
Shin, N.Y.4
Pozzi, A.5
Hanks, S.K.6
-
81
-
-
0032559562
-
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
-
Klemke RL, Leng J, Molander R, Brooks PC, Vuori K and Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol 1998; 140:961-972.
-
(1998)
J Cell Biol
, vol.140
, pp. 961-972
-
-
Klemke, R.L.1
Leng, J.2
Molander, R.3
Brooks, P.C.4
Vuori, K.5
Cheresh, D.A.6
-
82
-
-
0036153173
-
Dissection of HEF1-dependent functions in motility and transcriptional regulation
-
Fashena SJ, Einarson MB, O'Neill GM, Patriotis CP and Golemis EA. Dissection of HEF1-dependent functions in motility and transcriptional regulation. J. Cell. Sci. 2002; 115:99-111.
-
(2002)
J. Cell. Sci.
, vol.115
, pp. 99-111
-
-
Fashena, S.J.1
Einarson, M.B.2
O'Neill, G.M.3
Patriotis, C.P.4
Golemis, E.A.5
-
83
-
-
0033625871
-
Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells
-
Albert ML, Kim JI and Birge RB. alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat Cell Biol 2000; 2:899-905.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 899-905
-
-
Albert, M.L.1
Kim, J.I.2
Birge, R.B.3
-
84
-
-
0036629341
-
Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake
-
Bruce-Staskal PJ, Weidow CL, Gibson JJ and Bouton AH. Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake. J Cell Sci 2002; 115:2689-700.
-
(2002)
J Cell Sci
, vol.115
, pp. 2689-2700
-
-
Bruce-Staskal, P.J.1
Weidow, C.L.2
Gibson, J.J.3
Bouton, A.H.4
-
86
-
-
0031215023
-
The epithelial cell default-phenotype hypothesis and its implications for cancer
-
Frisch SM. The epithelial cell default-phenotype hypothesis and its implications for cancer. BioEssays 1997; 19:705-709.
-
(1997)
BioEssays
, vol.19
, pp. 705-709
-
-
Frisch, S.M.1
-
87
-
-
0034959232
-
Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics
-
O'Neill GM and Golemis EA. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol. Cell. Biol. 2001; 21:5094-5108.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5094-5108
-
-
O'Neill, G.M.1
Golemis, E.A.2
-
88
-
-
0034194714
-
Matrix survival signaling: From fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
-
Almeida EA, Ilic D, Han Q, Hauck CR, Jin F, Kawakatsu H, Schlaepfer DD and Damsky CH. Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase. J Cell Biol 2000; 149:741-54.
-
(2000)
J Cell Biol
, vol.149
, pp. 741-754
-
-
Almeida, E.A.1
Ilic, D.2
Han, Q.3
Hauck, C.R.4
Jin, F.5
Kawakatsu, H.6
Schlaepfer, D.D.7
Damsky, C.H.8
-
89
-
-
0032866076
-
Cas Mediates Transcriptional Activation of the Serum Response Element by Src
-
Hakak Y and Martin GS. Cas Mediates Transcriptional Activation of the Serum Response Element by Src. Mol Cell Biol 1999; 19:6953-6962.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6953-6962
-
-
Hakak, Y.1
Martin, G.S.2
-
90
-
-
13244273515
-
AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner
-
Felekkis KN, Narsimhan RP, Near R, Castro AF, Zheng Y, Quilliam LA and Lerner A. AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner. Mol Cancer Res 2005; 3:32-41.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 32-41
-
-
Felekkis, K.N.1
Narsimhan, R.P.2
Near, R.3
Castro, A.F.4
Zheng, Y.5
Quilliam, L.A.6
Lerner, A.7
-
91
-
-
0034684987
-
Bcar1/p130Cas protein and primary breast cancer: Prognosis and response to tamoxifen treatment
-
van der Flier S, Brinkman A, Look MP, Kok EM, Meijer-Van Gelder ME, Klijn JG, Dorssers LC and Foekens JA. Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment. J Natl Cancer Inst 2000; 92:120-7.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 120-127
-
-
Van Der Flier, S.1
Brinkman, A.2
Look, M.P.3
Kok, E.M.4
Meijer-Van Gelder, M.E.5
Klijn, J.G.6
Dorssers, L.C.7
Foekens, J.A.8
-
92
-
-
0034684997
-
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells
-
Brinkman A, van Der Flier S, Kok EM and Dorssers LC. BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells. J Natl Cancer Inst 2000; 92:112-20.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 112-120
-
-
Brinkman, A.1
Van Der Flier, S.2
Kok, E.M.3
Dorssers, L.C.4
-
93
-
-
0033797764
-
BCAR1/p130Cas expression in untreated and acquired tamoxifen-resistant human breast carcinomas
-
van der Flier S, Chan CM, Brinkman A, Smid M, Johnston SR, Dorssers LC and Dowsett M. BCAR1/p130Cas expression in untreated and acquired tamoxifen-resistant human breast carcinomas. Int J Cancer 2000; 89:465-8.
-
(2000)
Int J Cancer
, vol.89
, pp. 465-468
-
-
Van Der Flier, S.1
Chan, C.M.2
Brinkman, A.3
Smid, M.4
Johnston, S.R.5
Dorssers, L.C.6
Dowsett, M.7
-
94
-
-
0034770128
-
Tamoxifen resistance in breast cancer: Elucidating mechanisms
-
Dorssers LC, Van der Flier S, Brinkman A, van Agthoven T, Veldscholte J, Berns EM, Klijn JG, Beex LV and Foekens JA. Tamoxifen resistance in breast cancer: elucidating mechanisms. Drugs 2001; 61:1721-33.
-
(2001)
Drugs
, vol.61
, pp. 1721-1733
-
-
Dorssers, L.C.1
Van Der Flier, S.2
Brinkman, A.3
Van Agthoven, T.4
Veldscholte, J.5
Berns, E.M.6
Klijn, J.G.7
Beex, L.V.8
Foekens, J.A.9
-
95
-
-
0037438577
-
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42
-
Cai D, Felekkis KN, Near RI, O'Neill GM, van Seventer JM, Golemis EA and Lerner A. The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42. J Immunol 2003; 170:969-78.
-
(2003)
J Immunol
, vol.170
, pp. 969-978
-
-
Cai, D.1
Felekkis, K.N.2
Near, R.I.3
O'Neill, G.M.4
Van Seventer, J.M.5
Golemis, E.A.6
Lerner, A.7
-
96
-
-
0030941828
-
Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2
-
Manie SN, Astier A, Haghayeghi N, Canty T, Druker BJ, Hirai H and Freedman AS. Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2. J Biol Chem 1997; 272:15636-41.
-
(1997)
J Biol Chem
, vol.272
, pp. 15636-15641
-
-
Manie, S.N.1
Astier, A.2
Haghayeghi, N.3
Canty, T.4
Druker, B.J.5
Hirai, H.6
Freedman, A.S.7
-
97
-
-
33645219589
-
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
-
Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR and Gladson CL. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene 2005.
-
(2005)
Oncogene
-
-
Natarajan, M.1
Stewart, J.E.2
Golemis, E.A.3
Pugacheva, E.N.4
Alexandropoulos, K.5
Cox, B.D.6
Wang, W.7
Grammer, J.R.8
Gladson, C.L.9
-
98
-
-
24744452389
-
Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance
-
Seo S, Asai T, Saito T, Suzuki T, Morishita Y, Nakamoto T, Ichikawa M, Yamamoto G, Kawazu M, Yamagata T, Sakai R, Mitani K; Ogawa S, Kurokawa M, Chiba S and Hirai H. Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance. J Immunol 2005; 175:3492-501.
-
(2005)
J Immunol
, vol.175
, pp. 3492-3501
-
-
Seo, S.1
Asai, T.2
Saito, T.3
Suzuki, T.4
Morishita, Y.5
Nakamoto, T.6
Ichikawa, M.7
Yamamoto, G.8
Kawazu, M.9
Yamagata, T.10
Sakai, R.11
Mitani, K.12
Ogawa, S.13
Kurokawa, M.14
Chiba, S.15
Hirai, H.16
-
99
-
-
0031813880
-
Cell-cycle regulated processing of HEF1 to multiple protein forms differentially targeted to multiple compartments
-
Law SF, Zhang Y-Z, Klein-Szanto A and Golemis EA. Cell-cycle regulated processing of HEF1 to multiple protein forms differentially targeted to multiple compartments. Mol. Cell. Biol. 1998; 18:3540-3551.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3540-3551
-
-
Law, S.F.1
Zhang, Y.-Z.2
Klein-Szanto, A.3
Golemis, E.A.4
-
100
-
-
6944255304
-
Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid
-
Merrill RA, See AW, Wertheim ML and Clagett-Dame M. Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid. Dev Dyn 2004; 231:564-75.
-
(2004)
Dev Dyn
, vol.231
, pp. 564-575
-
-
Merrill, R.A.1
See, A.W.2
Wertheim, M.L.3
Clagett-Dame, M.4
-
101
-
-
24344483878
-
Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its amiproliterative and migratory responses
-
Levy L and Hill CS. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its amiproliterative and migratory responses. Mol Cell Biol 2005; 25:8108-25.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8108-8125
-
-
Levy, L.1
Hill, C.S.2
-
102
-
-
0037131380
-
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion
-
Zheng M and McKeown-Longo PJ. Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion. J Biol Chem 2002; 277:39599-608.
-
(2002)
J Biol Chem
, vol.277
, pp. 39599-39608
-
-
Zheng, M.1
McKeown-Longo, P.J.2
-
103
-
-
0034671642
-
A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member, HEF1
-
Liu X, Elia AEH, Law SF, Golemis EA, Farley J and Wang T. A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member, HEF1. EMBO J. 2000; 19:6759-6769.
-
(2000)
EMBO J.
, vol.19
, pp. 6759-6769
-
-
Liu, X.1
Aeh, E.2
Law, S.F.3
Golemis, E.A.4
Farley, J.5
Wang, T.6
-
104
-
-
33645216791
-
AIP4/hItch is an Ubiquitin E3 ligase for HEF1 in TGF-{beta} signaling pathways
-
Feng L, Guedes S and Wang T. AIP4/hItch is an Ubiquitin E3 ligase For HEF1 In TGF-{beta} signaling pathways. J Biol Chem 2004.
-
(2004)
J Biol Chem
-
-
Feng, L.1
Guedes, S.2
Wang, T.3
-
105
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15:740-6.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
106
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2:442-54.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
107
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL and Massague J. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436:518-24.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
108
-
-
0037769884
-
Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles
-
Faragher AJ and Fry AM. Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles. Mol Biol Cell 2003; 14:2876-89.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2876-2889
-
-
Faragher, A.J.1
Fry, A.M.2
-
109
-
-
0037101950
-
The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles
-
Mayor T, Hacker U, Stierhof YD and Nigg EA. The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. J Cell Sci 2002; 115:3275-84.
-
(2002)
J Cell Sci
, vol.115
, pp. 3275-3284
-
-
Mayor, T.1
Hacker, U.2
Stierhof, Y.D.3
Nigg, E.A.4
-
110
-
-
0032518798
-
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
-
Fry AM, Meraldi P and Nigg EA. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. Embo J 1998; 17:470-81.
-
(1998)
Embo J
, vol.17
, pp. 470-481
-
-
Fry, A.M.1
Meraldi, P.2
Nigg, E.A.3
-
111
-
-
26944442735
-
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
-
Zhao ZS, Lim JP, Ng YW, Lim L and Manser E. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell 2005; 20:237-49.
-
(2005)
Mol Cell
, vol.20
, pp. 237-249
-
-
Zhao, Z.S.1
Lim, J.P.2
Ng, Y.W.3
Lim, L.4
Manser, E.5
-
112
-
-
27644482717
-
Pak GITs to Aurora-A
-
Cotteret S and Chernoff J. Pak GITs to Aurora-A. Dev Cell 2005; 9:573-4.
-
(2005)
Dev Cell
, vol.9
, pp. 573-574
-
-
Cotteret, S.1
Chernoff, J.2
-
114
-
-
18544412767
-
Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor
-
Hirota T, Morisaki T, Nishiyama Y, Marumoto T, Tada K, Hara T, Masuko N, Inagaki M, Hatakeyama K and Saya H. Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor. J Cell Biol 2000; 149:1073-86.
-
(2000)
J Cell Biol
, vol.149
, pp. 1073-1086
-
-
Hirota, T.1
Morisaki, T.2
Nishiyama, Y.3
Marumoto, T.4
Tada, K.5
Hara, T.6
Masuko, N.7
Inagaki, M.8
Hatakeyama, K.9
Saya, H.10
-
115
-
-
27144473914
-
The extracellular matrix guides the orientation of the cell division axis
-
Thery M, Racine V, Pepin A, Piel M, Chen Y, Sibarita JB and Bornens M. The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol 2005; 7:947-53.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 947-953
-
-
Thery, M.1
Racine, V.2
Pepin, A.3
Piel, M.4
Chen, Y.5
Sibarita, J.B.6
Bornens, M.7
-
116
-
-
7744232293
-
Activation of a signaling cascade by cytoskeleton stretch
-
Tamada M, Sheetz MP and Sawada Y. Activation of a signaling cascade by cytoskeleton stretch. Dev Cell 2004; 7:709-18.
-
(2004)
Dev Cell
, vol.7
, pp. 709-718
-
-
Tamada, M.1
Sheetz, M.P.2
Sawada, Y.3
-
117
-
-
0031673072
-
A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos
-
Schumacher JM, Ashcroft N, Donovan PJ and Golden A. A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Development 1998; 125:4391-402.
-
(1998)
Development
, vol.125
, pp. 4391-4402
-
-
Schumacher, J.M.1
Ashcroft, N.2
Donovan, P.J.3
Golden, A.4
-
118
-
-
0037117408
-
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
-
Berdnik D and Knoblich JA. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol 2002; 12:640-7.
-
(2002)
Curr Biol
, vol.12
, pp. 640-647
-
-
Berdnik, D.1
Knoblich, J.A.2
-
119
-
-
1642406286
-
An aurora kinase is essential for flagellar disassembly in Chlamydomonas
-
Pan J, Wang Q and Snell WJ. An aurora kinase is essential for flagellar disassembly in Chlamydomonas. Dev Cell 2004; 6:445-51.
-
(2004)
Dev Cell
, vol.6
, pp. 445-451
-
-
Pan, J.1
Wang, Q.2
Snell, W.J.3
-
120
-
-
0035140597
-
New insights: Nephronophthisis-medullary cystic kidney disease
-
Hildebrandt F and Omram H. New insights: nephronophthisis-medullary cystic kidney disease. Pediatr Nephrol 2001; 16:168-76.
-
(2001)
Pediatr Nephrol
, vol.16
, pp. 168-176
-
-
Hildebrandt, F.1
Omram, H.2
-
121
-
-
0034630157
-
Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells
-
Donaldson JC, Dempsey PJ, Reddy S, Bouton AH, Coffey RJ and Hanks SK. Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells. Exp Cell Res 2000; 256:168-78.
-
(2000)
Exp Cell Res
, vol.256
, pp. 168-178
-
-
Donaldson, J.C.1
Dempsey, P.J.2
Reddy, S.3
Bouton, A.H.4
Coffey, R.J.5
Hanks, S.K.6
-
122
-
-
0035859888
-
Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2
-
U S A
-
Benzing T, Gerke P, Hopker K, Hildebrandt F, Kim E and Walz G. Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. Proc Natl Acad Sci U S A 2001; 98:9784-9.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 9784-9789
-
-
Benzing, T.1
Gerke, P.2
Hopker, K.3
Hildebrandt, F.4
Kim, E.5
Walz, G.6
-
123
-
-
0034672628
-
Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation
-
Geng L, Burrow CR, Li HP and Wilson PD. Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. Biochim Biophys Acta 2000; 1535:21-35.
-
(2000)
Biochim Biophys Acta
, vol.1535
, pp. 21-35
-
-
Geng, L.1
Burrow, C.R.2
Li, H.P.3
Wilson, P.D.4
-
124
-
-
0019833279
-
Multinucleation and inhibition of cytokinesis in suspended cells: Reversal upon reattachment to a substrate
-
Ben-Ze'ev A and Raz A. Multinucleation and inhibition of cytokinesis in suspended cells: reversal upon reattachment to a substrate. Cell 1981; 26:107-15.
-
(1981)
Cell
, vol.26
, pp. 107-115
-
-
Ben-Ze'ev, A.1
Raz, A.2
-
125
-
-
0018742870
-
Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium
-
Orly J and Sato G. Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium. Cell 1979; 17:295-305.
-
(1979)
Cell
, vol.17
, pp. 295-305
-
-
Orly, J.1
Sato, G.2
-
126
-
-
3843063704
-
Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration
-
Xie Z and Tsai L. H. Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration. Cell Cycle 2004; 3:108-10.
-
(2004)
Cell Cycle
, vol.3
, pp. 108-110
-
-
Xie, Z.1
Tsai, L.H.2
-
127
-
-
21644466387
-
Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53
-
Golubovskaya VM, Finch R and Cance WG. Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53. J Biol Chem 2005; 280:25008-21.
-
(2005)
J Biol Chem
, vol.280
, pp. 25008-25021
-
-
Golubovskaya, V.M.1
Finch, R.2
Cance, W.G.3
-
128
-
-
0033601745
-
Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: Role of mitosis-specific serine phosphorylation of FAK
-
Yamakita Y, Totsukawa G, Yamashiro S, Fry D, Zhang X, Hanks SK and Matsumura F. Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK. J Cell Biol 1999; 144:315-24.
-
(1999)
J Cell Biol
, vol.144
, pp. 315-324
-
-
Yamakita, Y.1
Totsukawa, G.2
Yamashiro, S.3
Fry, D.4
Zhang, X.5
Hanks, S.K.6
Matsumura, F.7
-
129
-
-
0035661624
-
Transcriptional Activation of Cyclin D1 Promoter by FAK Contributes to Cell Cycle Progression
-
Zhao J, Pestell R and Guan JL. Transcriptional Activation of Cyclin D1 Promoter by FAK Contributes to Cell Cycle Progression. Mol Biol Cell 2001; 12:4066-77.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 4066-4077
-
-
Zhao, J.1
Pestell, R.2
Guan, J.L.3
-
130
-
-
0035736485
-
Timing of cyclin D1 expression within G1 phase is controlled by Rho
-
Welsh CF, Roovers K, Villanueva J, Liu Y, Schwartz MA and Assoian RK. Timing of cyclin D1 expression within G1 phase is controlled by Rho. Nat Cell Biol 2001; 3:950-7.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 950-957
-
-
Welsh, C.F.1
Roovers, K.2
Villanueva, J.3
Liu, Y.4
Schwartz, M.A.5
Assoian, R.K.6
-
131
-
-
0037641217
-
Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases
-
Roovers K and Assoian RK. Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases. Mol Cell Biol 2003; 23:4283-94.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4283-4294
-
-
Roovers, K.1
Assoian, R.K.2
-
132
-
-
27144555447
-
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
-
Caussinus E and Gonzalez C. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet 2005; 37:1125-9.
-
(2005)
Nat Genet
, vol.37
, pp. 1125-1129
-
-
Caussinus, E.1
Gonzalez, C.2
-
133
-
-
18044391525
-
Aurora kinases, aneuploidy and cancer, a coincidence or a real link?
-
Giet R, Petretti C and Prigent C. Aurora kinases, aneuploidy and cancer, a coincidence or a real link? Trends Cell Biol 2005; 15:241-50.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 241-250
-
-
Giet, R.1
Petretti, C.2
Prigent, C.3
-
134
-
-
0036726312
-
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
-
Weaver VM, Lelievre S, Lakins JN, Chrenek MA, Jones JC, Giancotti F, Werb Z and Bissell MJ. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2002; 2:205-16.
-
(2002)
Cancer Cell
, vol.2
, pp. 205-216
-
-
Weaver, V.M.1
Lelievre, S.2
Lakins, J.N.3
Ma, C.4
Jones, J.C.5
Giancotti, F.6
Werb, Z.7
Bissell, M.J.8
-
135
-
-
0037020196
-
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
-
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK and Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 2002; 111:29-40.
-
(2002)
Cell
, vol.111
, pp. 29-40
-
-
Debnath, J.1
Mills, K.R.2
Collins, N.L.3
Reginato, M.J.4
Muthuswamy, S.K.5
Brugge, J.S.6
|