-
1
-
-
0002912139
-
Über die natur der centrosomen
-
in German
-
Boveri, T. Über die Natur der Centrosomen. Jena. Z. Med. Naturw. 28, 1-220 (1901) (in German).
-
(1901)
Jena. Z. Med. Naturw.
, vol.28
, pp. 1-220
-
-
Boveri, T.1
-
2
-
-
0035462382
-
Re-evaluating centrosome function
-
Doxsey, S. Re-evaluating centrosome function. Nature Rev. Mol. Cell Biol. 2, 688-698 (2001).
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 688-698
-
-
Doxsey, S.1
-
3
-
-
0036468420
-
Centrosome composition and microtubule anchoring mechanisms
-
Bornens, M. Centrosome composition and microtubule anchoring mechanisms. Curr. Opin. Cell Biol. 14, 25-34 (2002).
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 25-34
-
-
Bornens, M.1
-
4
-
-
0038142215
-
Polar expeditions - Provisioning the centrosome for mitosis
-
Blagden, S. P. & Glover, D. M. Polar expeditions - provisioning the centrosome for mitosis. Nature Cell Biol. 5, 505-511 (2003).
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 505-511
-
-
Blagden, S.P.1
Glover, D.M.2
-
5
-
-
84955645671
-
-
Wiley-VCH, Weinheim
-
Nigg, E. A. Centrosomes in Development and Disease (Wiley-VCH, Weinheim, 2004). This comprehensive book is focused on the centrosome and its associated proteins.
-
(2004)
Centrosomes in Development and Disease
-
-
Nigg, E.A.1
-
6
-
-
0033080404
-
Role of microtubules in the organization of the Golgi complex
-
Thyberg, J. & Moskalewski, S. Role of microtubules in the organization of the Golgi complex. Exp. Cell Res. 246, 263-279 (1999).
-
(1999)
Exp. Cell Res.
, vol.246
, pp. 263-279
-
-
Thyberg, J.1
Moskalewski, S.2
-
7
-
-
0033971720
-
Centrosome-independent mitotic spindle formation in vertebrates
-
Khodjakov, A., Cole, R. W., Oakley, B. R. & Rieder, C. L. Centrosome-independent mitotic spindle formation in vertebrates. Curr. Biol. 10, 59-67 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 59-67
-
-
Khodjakov, A.1
Cole, R.W.2
Oakley, B.R.3
Rieder, C.L.4
-
8
-
-
0035936898
-
Requirement of a centrosomal activity for cell cycle progression through G1 into S phase
-
Hinchcliffe, E. H., Miller, F. J., Cham, M., Khodjakov, A. & Sluder, G. Requirement of a centrosomal activity for cell cycle progression through G1 into S phase. Science 291, 1547-1550 (2001). This paper elegantly shows, using laser ablation, that centrosomes are not necessary to complete mitosis once cells are in S phase, but are required for the progression from G1 into S phase.
-
(2001)
Science
, vol.291
, pp. 1547-1550
-
-
Hinchcliffe, E.H.1
Miller, F.J.2
Cham, M.3
Khodjakov, A.4
Sluder, G.5
-
9
-
-
8544263424
-
Functional role of centrosomes in spindle assembly and organization
-
Varmark, H. Functional role of centrosomes in spindle assembly and organization, J. Cell. Biochem. 91, 904-914 (2004).
-
(2004)
J. Cell. Biochem.
, vol.91
, pp. 904-914
-
-
Varmark, H.1
-
10
-
-
0035873385
-
'It takes two to tango': Understanding how centrosome duplication is regulated throughout the cell cycle
-
Hinchcliffe, E. H. & Sluder, G. 'It takes two to tango': understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev. 15, 1167-1181 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 1167-1181
-
-
Hinchcliffe, E.H.1
Sluder, G.2
-
11
-
-
0014250991
-
The centriole cycle in synchronized HeLa cells
-
Bobbins, E., Jentzsch, G. & Micali, A. The centriole cycle in synchronized HeLa cells. J. Cell Biol. 36, 329-339 (1968).
-
(1968)
J. Cell Biol.
, vol.36
, pp. 329-339
-
-
Bobbins, E.1
Jentzsch, G.2
Micali, A.3
-
12
-
-
0036831681
-
Centrosome aberrations: Cause or consequence of cancer progression?
-
Nigg, E. A. Centrosome aberrations: cause or consequence of cancer progression? Nature Rev. Cancer 2, 815-825 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 815-825
-
-
Nigg, E.A.1
-
13
-
-
0033106326
-
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
Xu, X. et al. Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol. Cell 3, 389-395 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 389-395
-
-
Xu, X.1
-
14
-
-
0032170033
-
Centrosome defects and genetic instability in malignant tumors
-
Rhan, G. A. et al. Centrosome defects and genetic instability in malignant tumors. Cancer Res. 58, 3974-3985 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 3974-3985
-
-
Rhan, G.A.1
-
15
-
-
0029881977
-
Abnormal centrosome amplification in the absence of p53
-
Fukasawa, K., Choi, T., Kuriyama, R., Rulong, S. & Vande Woude, G. F. Abnormal centrosome amplification in the absence of p53. Science 271, 1744-1747 (1996).
-
(1996)
Science
, vol.271
, pp. 1744-1747
-
-
Fukasawa, K.1
Choi, T.2
Kuriyama, R.3
Rulong, S.4
Vande Woude, G.F.5
-
16
-
-
0032467050
-
Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected
-
Brinkley, B. R. & Goepfert, T. M. Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected. Cell Motil. Cytoskeleton 41, 281-288 (1998).
-
(1998)
Cell Motil. Cytoskeleton
, vol.41
, pp. 281-288
-
-
Brinkley, B.R.1
Goepfert, T.M.2
-
17
-
-
0037444168
-
Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas
-
Pihan, G. A., Wallace, J., Zhou, Y. & Doxsey, S. J. Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas. Cancer Res. 63, 1393-1404 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 1393-1404
-
-
Pihan, G.A.1
Wallace, J.2
Zhou, Y.3
Doxsey, S.J.4
-
18
-
-
0642286494
-
Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins
-
Duensing, S. & Munger, K. Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Prog. Cell Cycle Res. 5, 383-391 (2003).
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 383-391
-
-
Duensing, S.1
Munger, K.2
-
19
-
-
0034730196
-
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
-
Duensing, S, et al. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc. Natl Acad. Sci. USA 97, 10002-10007 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10002-10007
-
-
Duensing, S.1
-
20
-
-
4043107077
-
GMAP-210 recruits γ-tubulin complexes to cis-Golgi membranes and is required for Golgi ribbon formation
-
Rios, R. M., Sanchis, A., Tassin, A. M., Fedriani, C. & Bomens, M. GMAP-210 recruits γ-tubulin complexes to cis-Golgi membranes and is required for Golgi ribbon formation. Cell 118, 323-335 (2004).
-
(2004)
Cell
, vol.118
, pp. 323-335
-
-
Rios, R.M.1
Sanchis, A.2
Tassin, A.M.3
Fedriani, C.4
Bomens, M.5
-
21
-
-
0346874342
-
Proteomic characterization of the human centrosome by protein correlation profiling
-
Andersen, J. S. et al. Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426, 570-574 (2003). This is the first global study of the protein content of the centrosome using a proteomics approach.
-
(2003)
Nature
, vol.426
, pp. 570-574
-
-
Andersen, J.S.1
-
22
-
-
1942534004
-
Regulation of the TGFβ signalling pathway by ubiquitin-mediated degradation
-
Izzi, L. & Attisano, L. Regulation of the TGFβ signalling pathway by ubiquitin-mediated degradation. Oncogene 23, 2071-2078 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 2071-2078
-
-
Izzi, L.1
Attisano, L.2
-
23
-
-
3943055513
-
Ubiquitin-dependent regulation of the synapse
-
DiAntonio, A. & Hicke, L. Ubiquitin-dependent regulation of the synapse. Annu. Rev. Neurosci. 27, 223-246 (2004).
-
(2004)
Annu. Rev. Neurosci.
, vol.27
, pp. 223-246
-
-
Diantonio, A.1
Hicke, L.2
-
24
-
-
0036284778
-
The anaphase-promoting complex: Proteolysis in mitosis and beyond
-
Peters, J. M. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol. Cell 9, 931-943 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 931-943
-
-
Peters, J.M.1
-
25
-
-
1542344435
-
Proteasomes and their kin: Proteases in the machine age
-
Pickart, C. M. & Cohen, R. E. Proteasomes and their kin: proteases in the machine age. Nature Rev. Mol. Cell Biol. 5, 177-187 (2004). A comprehensive review of ubiquitin-proteasome protein degradation.
-
(2004)
Nature Rev. Mol. Cell Biol.
, vol.5
, pp. 177-187
-
-
Pickart, C.M.1
Cohen, R.E.2
-
26
-
-
0029909097
-
Ubiquitin-mediated proteolysis centers in HeLa cells: Indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome
-
Wojcik, C., Schroeter, D., Wilk, S., Lamprecht, J. & Paweletz, N. Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome. Eur. J. Cell Biol. 71, 311-318 (1996).
-
(1996)
Eur. J. Cell Biol.
, vol.71
, pp. 311-318
-
-
Wojcik, C.1
Schroeter, D.2
Wilk, S.3
Lamprecht, J.4
Paweletz, N.5
-
27
-
-
0345593387
-
Dynamic association of proteasomal machinery with the centrosome
-
Wigley, W. C. et al. Dynamic association of proteasomal machinery with the centrosome. J. Cell Biol. 145, 481-490 (1999). This article shows the centrosomal localization of various members of the ubiquitin-proteasome degradation pathway, indicating that the centrosome functions as a cellular centre for protein folding, aggregation and proteolysis.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 481-490
-
-
Wigley, W.C.1
-
28
-
-
0034614416
-
Activity and regulation of the centrosome-associated proteasome
-
Fabunmi, R. P., Wigley, W. C., Thomas, P. J. & DeMartino, G. N. Activity and regulation of the centrosome-associated proteasome. J. Biol. Chem. 275, 409-413 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 409-413
-
-
Fabunmi, R.P.1
Wigley, W.C.2
Thomas, P.J.3
DeMartino, G.N.4
-
29
-
-
0036092459
-
The intracellular localization of the proteasome
-
Gordon, C. The intracellular localization of the proteasome. Curr. Top. Microbiol. Immunol. 268, 175-184 (2002).
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.268
, pp. 175-184
-
-
Gordon, C.1
-
30
-
-
0037417254
-
Alzheimers disease and Parkinson's disease
-
Nussbaum, R. L. & Ellis, C. E. Alzheimers disease and Parkinson's disease. N. Engl. J. Med. 348, 1356-1364 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1356-1364
-
-
Nussbaum, R.L.1
Ellis, C.E.2
-
31
-
-
0030015934
-
Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism
-
Ishikawa, A. & Tsuji, S. Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism. Neurology 47, 160-166 (1996).
-
(1996)
Neurology
, vol.47
, pp. 160-166
-
-
Ishikawa, A.1
Tsuji, S.2
-
32
-
-
0028198309
-
Familial juvenile parkinsonism: Clinical and pathologic study in a family
-
Takahashi, H. et al. Familial juvenile parkinsonism: clinical and pathologic study in a family. Neurology 44, 437-441 (1994).
-
(1994)
Neurology
, vol.44
, pp. 437-441
-
-
Takahashi, H.1
-
33
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T. et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608 (1998).
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
-
34
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai, Y., Soda, M. & Takahashi, R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem. 275, 35661-35664 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
35
-
-
0033933048
-
Family Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H. et al. Family Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nature Genet. 25, 302-305 (2000). The authors report that parkin is a ubiquitin-protein ligase, raising the possibility that accumulation of parkin targets might underlie the pathogenesis of Parkinson disease.
-
(2000)
Nature Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
-
36
-
-
0142074728
-
Parkin is recruited to the centrosome in response to inhibition of proteasomes
-
Zhao, J., Ren, Y., Jang, Q. & Feng, J. Parkin is recruited to the centrosome in response to inhibition of proteasomes. J. Cell Sci. 116, 4011-4019 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4011-4019
-
-
Zhao, J.1
Ren, Y.2
Jang, Q.3
Feng, J.4
-
37
-
-
0032568534
-
α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M, & Goedert, M. α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl Acad. Sci. USA 95, 6469-6473 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
38
-
-
0030882856
-
α-synudein in Lewy bodies
-
Spillantini, M. G. et al. α-Synudein in Lewy bodies. Nature 388, 839-840 (1997).
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
-
39
-
-
0036316947
-
Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
-
McNaught, K. S. et al. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J. Neurochem. 81, 301-306 (2002).
-
(2002)
J. Neurochem.
, vol.81
, pp. 301-306
-
-
McNaught, K.S.1
-
40
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi, K. et al. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann. Neurol. 47, 521-523 (2000).
-
(2000)
Ann. Neurol.
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
-
41
-
-
0029904487
-
NACR a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A. & Lansbury, P. T. Jr. NACR a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35, 13709-13715 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
-
42
-
-
0031696092
-
Structure/function in neuroprotection and apoptosis
-
Borden, K. L. Structure/function in neuroprotection and apoptosis. Ann. Neurol. 44, S65-S71 (1998).
-
(1998)
Ann. Neurol.
, vol.44
-
-
Borden, K.L.1
-
43
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson's disease
-
Conway, K. A., Harper, J. D. & Lansbury, P. T. Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson's disease. Nature Med. 4, 1381-1320 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 1381-11320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
44
-
-
0034681163
-
Acceleration of oligomenzation, not fibrillization, is a shared property of both α-syunclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway, K. A. et al. Acceleration of oligomenzation, not fibrillization, is a shared property of both α-syunclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc. Natl Acad. Sci. USA 91, 571-576 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 571-576
-
-
Conway, K.A.1
-
45
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M. H. et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047 (1997).
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
-
46
-
-
0033607801
-
Degradation of α-synuclein by proteasome
-
Bennett, M. C. et al. Degradation of α-synuclein by proteasome. J. Biol. Chem. 274, 33855-33858 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33855-33858
-
-
Bennett, M.C.1
-
47
-
-
0035253217
-
Macromolecular crowding: An important but neglected aspect of the intracellular environment
-
Ellis, R. J. Macromolecular crowding: an important but neglected aspect of the intracellular environment. Curr. Opin. Struct. Biol. 11, 114-119 (2001).
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 114-119
-
-
Ellis, R.J.1
-
48
-
-
0037177250
-
Molecular crowding accelerates fibrillization of α-synuclein: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease?
-
Shtilerman, M. D., Ding, T. T. & Lansbury, P. T. Molecular crowding accelerates fibrillization of α-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease? Biochemistry 41, 3855-3860 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 3855-3860
-
-
Shtilerman, M.D.1
Ding, T.T.2
Lansbury, P.T.3
-
49
-
-
0037181497
-
Accelerated α-synuclein fibrillization in crowded milieu
-
Uversky, V. N., Cooper, E. M., Bower, K. S., Li, J. & Fink, A. L. Accelerated α-synuclein fibrillization in crowded milieu. FEBS Lett. 515, 99-103 (2002).
-
(2002)
FEBS Lett.
, vol.515
, pp. 99-103
-
-
Uversky, V.N.1
Cooper, E.M.2
Bower, K.S.3
Li, J.4
Fink, A.L.5
-
50
-
-
0037031651
-
New directions in neuronal migration
-
Hatten, M. E. New directions in neuronal migration. Science 297, 1660-1663 (2002).
-
(2002)
Science
, vol.297
, pp. 1660-1663
-
-
Hatten, M.E.1
-
51
-
-
0019791275
-
Distribution of microtubule organizing centers in migrating sheets of endothelial cells
-
Gotlieb, A. I., May, L. M., Subrahmanyan, L. & Kalnins, V. I. Distribution of microtubule organizing centers in migrating sheets of endothelial cells. J. Cell Biol. 91, 589-594 (1981).
-
(1981)
J. Cell Biol.
, vol.91
, pp. 589-594
-
-
Gotlieb, A.I.1
May, L.M.2
Subrahmanyan, L.3
Kalnins, V.I.4
-
52
-
-
0030928756
-
Centrosome positioning and directionality of cell movements
-
Ueda, M., Graf, R., MacWilliams, H. K., Schliwa, M. & Euteneuer, U. Centrosome positioning and directionality of cell movements. Proc. Natl Acad. Sci. USA 94, 9674-9678 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9674-9678
-
-
Ueda, M.1
Graf, R.2
MacWilliams, H.K.3
Schliwa, M.4
Euteneuer, U.5
-
53
-
-
0033136701
-
Genetic malformations of the human cerebral cortex
-
Walsh, C. A. Genetic malformations of the human cerebral cortex. Neuron 23, 19-29 (1999).
-
(1999)
Neuron
, vol.23
, pp. 19-29
-
-
Walsh, C.A.1
-
54
-
-
0035868823
-
LIS1 and dynein motor function in neuronal migration and development
-
Wynshaw-Boris, A. & Gambello, M. J. LIS1 and dynein motor function in neuronal migration and development. Genes Dev. 15, 639-651 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 639-651
-
-
Wynshaw-Boris, A.1
Gambello, M.J.2
-
55
-
-
0033153135
-
Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons
-
Francis, F. et al. Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Neuron 23, 247-256 (1999).
-
(1999)
Neuron
, vol.23
, pp. 247-256
-
-
Francis, F.1
-
56
-
-
0028023599
-
Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase
-
Hattori, M., Adachi, H., Tsujimoto, M., Arai, H. & Inoue, K. Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase. Nature 370, 216-218 (1994).
-
(1994)
Nature
, vol.370
, pp. 216-218
-
-
Hattori, M.1
Adachi, H.2
Tsujimoto, M.3
Arai, H.4
Inoue, K.5
-
57
-
-
0027176708
-
Isolation of a Miller-Dieker lissencephaly gene containing G protein β-subunit-like repeats
-
Reiner, O. et al. Isolation of a Miller-Dieker lissencephaly gene containing G protein β-subunit-like repeats. Nature 364, 717-721 (1993).
-
(1993)
Nature
, vol.364
, pp. 717-721
-
-
Reiner, O.1
-
58
-
-
0031735518
-
Nuclear migration, nucleokinesis and lissencephaly
-
Morris, N. R., Efimov, V. P. & Xiang, X. Nuclear migration, nucleokinesis and lissencephaly. Trends Cell Biol. 8, 467-470 (1998).
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 467-470
-
-
Morris, N.R.1
Efimov, V.P.2
Xiang, X.3
-
59
-
-
0038709367
-
Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependent
-
Zhang, J., Li, S., Fischer, R. & Xiang, X. Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependent. Mol. Biol. Cell 14, 1479-1488 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1479-1488
-
-
Zhang, J.1
Li, S.2
Fischer, R.3
Xiang, X.4
-
60
-
-
0030695246
-
Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit
-
Sapir, T., Elbaum, M. & Reiner, O. Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit. EMBO J. 16, 6977-6984 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 6977-6984
-
-
Sapir, T.1
Elbaum, M.2
Reiner, O.3
-
61
-
-
0033769717
-
Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1
-
Smith, D. S. et al. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nature Cell Biol. 2, 767-775 (2000). This paper describes the interaction between LIS1 and dynein, and the role of LIS1 in the regulation of dynein activity with emphasis on neuronal migration and axonal growth.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 767-775
-
-
Smith, D.S.1
-
62
-
-
0037049545
-
Microtubule release from the centrosome in migrating cells
-
Abal, M. et al. Microtubule release from the centrosome in migrating cells. J. Cell Biol. 159, 731-737 (2002).
-
(2002)
J. Cell Biol.
, vol.159
, pp. 731-737
-
-
Abal, M.1
-
63
-
-
0030850709
-
Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans
-
Wins, D. A., Liu, B., Xiang, X. & Morris, N. R. Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans. Mol. Gen. Genet 255, 194-200 (1997).
-
(1997)
Mol. Gen. Genet.
, vol.255
, pp. 194-200
-
-
Wins, D.A.1
Liu, B.2
Xiang, X.3
Morris, N.R.4
-
64
-
-
0032493049
-
The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC
-
Morris, S. M., Albrecht, U., Reiner, O., Eichele, G. & Yu-Lee, L. Y. The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. Curr. Biol. 8, 603-606 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 603-606
-
-
Morris, S.M.1
Albrecht, U.2
Reiner, O.3
Eichele, G.4
Yu-Lee, L.Y.5
-
65
-
-
0035893238
-
NudC associates with Lis1 and the dynein motor at the leading pole of neurons
-
Aumais, J. P. et al. NudC associates with Lis1 and the dynein motor at the leading pole of neurons. J. Neurosci. 21, RC187 (2001).
-
(2001)
J. Neurosci.
, vol.21
-
-
Aumais, J.P.1
-
66
-
-
0034520636
-
NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein
-
Niethammer, M. et al. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron 28, 697-711 (2000).
-
(2000)
Neuron
, vol.28
, pp. 697-711
-
-
Niethammer, M.1
-
67
-
-
0034520597
-
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system
-
Sasaki, S. et al. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron 28, 681-696 (2000).
-
(2000)
Neuron
, vol.28
, pp. 681-696
-
-
Sasaki, S.1
-
68
-
-
0034517593
-
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome
-
Feng, Y. et al. LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron 28, 665-679 (2000).
-
(2000)
Neuron
, vol.28
, pp. 665-679
-
-
Feng, Y.1
-
69
-
-
0346120151
-
Cytoskeletal-associated proteins in the migration of cortical neurons
-
Bielas, S. L. & Gleeson, J. G. Cytoskeletal-associated proteins in the migration of cortical neurons. J. Neurobiol. 58, 149-159 (2004).
-
(2004)
J. Neurobiol.
, vol.58
, pp. 149-159
-
-
Bielas, S.L.1
Gleeson, J.G.2
-
70
-
-
5144228139
-
Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning
-
Shu, T. et al. Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron 44, 263-277 (2004). This shows the role of NDEL1 in facilitating the interaction between LIS1 and dynein, its impact in the regulation of dynein activity, and its role in neuronal migration in mice.
-
(2004)
Neuron
, vol.44
, pp. 263-277
-
-
Shu, T.1
-
71
-
-
0037385481
-
Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3
-
Cardoso, C. et al. Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3. Am. J. Hum. Genet 72, 918-930 (2003).
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 918-930
-
-
Cardoso, C.1
-
72
-
-
0038757833
-
14-3-3ε is important for neuronal migration by binding to NUDEL: A molecular explanation for Miller-Dieker syndrome
-
Toyo-oka, K. et al. 14-3-3ε is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nature Genet 34, 274-285 (2003). The authors show that 14-3-3ε is involved in neuronal migration, binds to CDK5-p35-phosphorylated NDEL1 to maintain it in its phosphorylated state, and links the CDK5-D35 and LIS1 pathways of neuronal migration.
-
(2003)
Nature Genet.
, vol.34
, pp. 274-285
-
-
Toyo-oka, K.1
-
73
-
-
0028944942
-
Motility and cytoskeletal organization of migrating cerebellar granule neurons
-
Rivas, R. J. & Hatten, M. E. Motility and cytoskeletal organization of migrating cerebellar granule neurons. J. Neurosci. 15, 981-989 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 981-989
-
-
Rivas, R.J.1
Hatten, M.E.2
-
74
-
-
2942640554
-
Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration
-
Tanaka, T. et al. Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J. Cell Biol. 165, 709-721 (2004).
-
(2004)
J. Cell Biol.
, vol.165
, pp. 709-721
-
-
Tanaka, T.1
-
75
-
-
19244375809
-
Doublecortin mutations cluster in evolutionarily conserved functional domains
-
Sapir, T. et al. Doublecortin mutations cluster in evolutionarily conserved functional domains. Hum. Mol. Genet 9, 701-712 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 701-712
-
-
Sapir, T.1
-
76
-
-
0032832998
-
Doublecortin, a stabilizer of microtubules
-
Horesh, D. et al. Doublecortin, a stabilizer of microtubules. Hum. Mol. Genet. 8, 1599-1610 (1999).
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1599-1610
-
-
Horesh, D.1
-
77
-
-
0034703283
-
Interaction between LIS1 and doublecortin, two lissencephaly gene products
-
Caspi, M., Atlas, R., Kantor, A., Sapir, T. & Reiner, O. Interaction between LIS1 and doublecortin, two lissencephaly gene products. Hum. Mol. Genet. 9, 2205-2213 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2205-2213
-
-
Caspi, M.1
Atlas, R.2
Kantor, A.3
Sapir, T.4
Reiner, O.5
-
78
-
-
1942504197
-
DISC1 localizes to the centrosome by binding to kendrin
-
Myoshi, K. et al. DISC1 localizes to the centrosome by binding to kendrin. Biochem. Biophys. Res. Commun. 317, 1195-1199 (2004).
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.317
, pp. 1195-1199
-
-
Myoshi, K.1
-
79
-
-
0037766786
-
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation
-
Morris, J. A., Kandpal, G., Ma, L. & Austin, C. P. DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum. Mol. Genet. 12, 1591-1608 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1591-1608
-
-
Morris, J.A.1
Kandpal, G.2
Ma, L.3
Austin, C.P.4
-
80
-
-
0034982847
-
Molecular genetics of bipolar disorder
-
Kato, T. Molecular genetics of bipolar disorder. Neurosci. Res. 40, 105-113 (2001).
-
(2001)
Neurosci. Res.
, vol.40
, pp. 105-113
-
-
Kato, T.1
-
81
-
-
10744229990
-
Disrupted in schizophrenia 1 and nudel form a neurodevelopmentally regulated protein complex: Implications for schizophrenia and other major neurological disorders
-
Brandon, N. J. et al. Disrupted in schizophrenia 1 and nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol. Cell. Neurosci. 25, 42-55 (2004).
-
(2004)
Mol. Cell. Neurosci.
, vol.25
, pp. 42-55
-
-
Brandon, N.J.1
-
82
-
-
0042622356
-
Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
-
Miyoshi, K. et al. Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol. Psychiatry 8, 685-694 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 685-694
-
-
Miyoshi, K.1
-
83
-
-
0037422609
-
Disrupted-in-schizophrenia-1 (DISC-1): Mutant truncation prevents binding to nudE-like (NUDEL) and inhibits neurite outgrowth
-
Ozeki, Y. et al. Disrupted-in-schizophrenia-1 (DISC-1): mutant truncation prevents binding to nudE-like (NUDEL) and inhibits neurite outgrowth. Proc. Natl Acad. Sci. USA 100, 289-294 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 289-294
-
-
Ozeki, Y.1
-
84
-
-
0032567765
-
Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon
-
Ahmad, F. J., Echeverri, C. J., Vallee, R. B. & Baas, P. W. Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J. Cell Biol. 140, 391-401 (1998).
-
(1998)
J. Cell Biol.
, vol.140
, pp. 391-401
-
-
Ahmad, F.J.1
Echeverri, C.J.2
Vallee, R.B.3
Baas, P.W.4
-
85
-
-
0029093287
-
Microtubules released from the neuronal centrosome are transported into the axon
-
Ahmad, F. J. & Baas, P. W. Microtubules released from the neuronal centrosome are transported into the axon. J. Cell Sci. 108, 2761-2769 (1995).
-
(1995)
J. Cell Sci.
, vol.108
, pp. 2761-2769
-
-
Ahmad, F.J.1
Baas, P.W.2
-
86
-
-
0028324308
-
Inhibition of microtubule nucleation at the neuronal centrosome compromises axon growth
-
Ahmad, F. J., Joshi, H. C., Centonze, V. E. & Baas, P. W. Inhibition of microtubule nucleation at the neuronal centrosome compromises axon growth. Neuron 12, 271-280 (1994).
-
(1994)
Neuron
, vol.12
, pp. 271-280
-
-
Ahmad, F.J.1
Joshi, H.C.2
Centonze, V.E.3
Baas, P.W.4
-
87
-
-
2942531080
-
Hereditary spastic paraplegia: Spastin phenotype and function
-
Fink, J. K. & Rainier, S. Hereditary spastic paraplegia: spastin phenotype and function. Arch. Neurol. 61, 830-633 (2004).
-
(2004)
Arch. Neurol.
, vol.61
, pp. 830-1633
-
-
Fink, J.K.1
Rainier, S.2
-
88
-
-
0032721512
-
Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia
-
Hazan, J. et al. Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia. Nature Genet. 23, 296-303 (1999).
-
(1999)
Nature Genet.
, vol.23
, pp. 296-303
-
-
Hazan, J.1
-
89
-
-
3042853307
-
Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules
-
Karabay, A., Yu, W., Solowska, J. M., Baird, D. H. & Baas, P. W. Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules. J. Neurosci. 24, 5778-5788 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 5778-5788
-
-
Karabay, A.1
Yu, W.2
Solowska, J.M.3
Baird, D.H.4
Baas, P.W.5
-
90
-
-
0027424297
-
Identification of katanin, an ATPase that severs and disassembles stable microtubules
-
McNally, F. J. & Vale, R. D. Identification of katanin, an ATPase that severs and disassembles stable microtubules. Cell 75, 419-429 (1993).
-
(1993)
Cell
, vol.75
, pp. 419-429
-
-
McNally, F.J.1
Vale, R.D.2
-
91
-
-
5744240094
-
Spastin interacts with the centrosomal protein NA14, and is enriched in the spindle pole, the midbody and the distal axon
-
Errico, A., Claudiani, P., D'Addio, M. & Rugarti, E. I. Spastin interacts with the centrosomal protein NA14, and is enriched in the spindle pole, the midbody and the distal axon. Hum. Mol. Genet. 13, 2121-2132 (2004). This paper shows the subcellular localization of spastin to regions of dynamic microtubule organization, including the centrosome, providing an intriguing explanation for axonal degeneration in hereditary spastic paraplegia.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2121-2132
-
-
Errico, A.1
Claudiani, P.2
D'Addio, M.3
Rugarti, E.I.4
-
92
-
-
3142647116
-
The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function
-
Trotta, N., Orso, G., Rossetto, M. G., Daga, A. & Broadie, K. The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr. Biol. 14, 1135-1147 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 1135-1147
-
-
Trotta, N.1
Orso, G.2
Rossetto, M.G.3
Daga, A.4
Broadie, K.5
-
93
-
-
0037730408
-
Chlamydomonas DIP13 and human NA14: A new class of proteins associated with microtubule structures is involved in cell division
-
Pfannenschmid, F. et al. Chlamydomonas DIP13 and human NA14: a new class of proteins associated with microtubule structures is involved in cell division. J. Cell Sci. 116, 1449-1462 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1449-1462
-
-
Pfannenschmid, F.1
-
95
-
-
0041656292
-
The hunt for huntingtin function: Interaction partners tell many different stones
-
Harjes, P. & Wanker, E. E. The hunt for huntingtin function: interaction partners tell many different stones. Trends Biochem. Sci. 28, 425-433 (2003).
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 425-433
-
-
Harjes, P.1
Wanker, E.E.2
-
96
-
-
0030726894
-
Glued subunit of dynactin
-
Glued subunit of dynactin. Hum. Mol. Genet 6, 2205-2212 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2205-2212
-
-
Engelender, S.1
-
97
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier, L. R. et al. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118, 127-138 (2004). This article demonstrates that the huntingtin protein is involved in vesicular transport of brain-derived neurotrophic factor (BDNF) along microtubules and proposes that defects in this process are relevant to Huntington disease.
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
-
98
-
-
0030986659
-
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
-
Kalchman, M. A. et al. HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain. Nature Genet. 16, 44-53 (1997).
-
(1997)
Nature Genet.
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
-
99
-
-
0031056478
-
HIP-I: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
Wanker, E. E. et al. HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system. Hum. Mol. Genet 6, 487-495 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.E.1
-
100
-
-
0036173770
-
Recruitment and actuation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
-
Gervais, F. G. et al. Recruitment and actuation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nature Cell Biol. 4, 95-105 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 95-105
-
-
Gervais, F.G.1
-
101
-
-
0141706698
-
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia
-
Baker, S. A., Freeman, K., Luby-Phelps, K., Pazour, G. J. & Besharse, J. C. IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. J. Biol. Chem. 278, 34211-34218 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34211-34218
-
-
Baker, S.A.1
Freeman, K.2
Luby-Phelps, K.3
Pazour, G.J.4
Besharse, J.C.5
-
102
-
-
0036544554
-
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance
-
Pazour, G. J. et al. The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J. Cell Biol. 157, 103-113 (2002).
-
(2002)
J. Cell Biol.
, vol.157
, pp. 103-113
-
-
Pazour, G.J.1
-
103
-
-
0035504960
-
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients
-
Sathasivam, K. et al. Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients. Hum. Mol. Genet. 10, 2425-2435 (2001).
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2425-2435
-
-
Sathasivam, K.1
-
104
-
-
0037227766
-
The vertebrate primary cilium is a sensory organelle
-
Pazour, G. J. & Witman, G. B. The vertebrate primary cilium is a sensory organelle. Curr. Opin. Cell Biol. 15, 105-110 (2003).
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 105-110
-
-
Pazour, G.J.1
Witman, G.B.2
-
105
-
-
0036844195
-
Intraflagellar transport
-
Rosenbaum, J. L. & Witman, G. B. Intraflagellar transport. Nature Rev. Mol. Cell Biol. 3, 813-825 (2002). A comprehensive review that describes the ultrastructure of cilia, flagella, the process of intraflagellar transport and some of the phenotypic consequences of perturbations in this process.
-
(2002)
Nature Rev. Mol. Cell Biol.
, vol.3
, pp. 813-825
-
-
Rosenbaum, J.L.1
Witman, G.B.2
-
106
-
-
0027158027
-
Reversal of left-right asymmetry: A situs inversus mutation
-
Yokoyama, T. et al. Reversal of left-right asymmetry: a situs inversus mutation. Science 260, 679-682 (1993).
-
(1993)
Science
, vol.260
, pp. 679-682
-
-
Yokoyama, T.1
-
107
-
-
1342302885
-
A perspective on inversin
-
Eley, L. et al. A perspective on inversin. Cell Biol. Int. 28, 119-124 (2004).
-
(2004)
Cell Biol. Int.
, vol.28
, pp. 119-124
-
-
Eley, L.1
-
108
-
-
0037115494
-
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
-
Morgan, D. et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum. Mol. Genet 11, 3345-3350 (2002).
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 3345-3350
-
-
Morgan, D.1
-
109
-
-
0037959910
-
The left-right determinant inversin is a component of node monocilia and other 9+0 cilia
-
Watanabe, D. et al. The left-right determinant inversin is a component of node monocilia and other 9+0 cilia. Development 130, 1725-1734 (2003). The authors describe the subcellular localization patterns of inversin, as well as the specific expression of this protein in primary cilia.
-
(2003)
Development
, vol.130
, pp. 1725-1734
-
-
Watanabe, D.1
-
110
-
-
0001577217
-
Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells
-
Sorokin, S. Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells. J. Cell Biol. 15, 363-377 (1962).
-
(1962)
J. Cell Biol.
, vol.15
, pp. 363-377
-
-
Sorokin, S.1
-
111
-
-
1842579395
-
The oligogenic properties of Bardet-Biedl syndrome
-
Katsanis, N. The oligogenic properties of Bardet-Biedl syndrome. Hum. Mol. Genet. 13, R65-R71 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
-
-
Katsanis, N.1
-
112
-
-
4444254983
-
Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
-
Kulaga, H. M. et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nature Genet 36, 994-998 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 994-998
-
-
Kulaga, H.M.1
-
113
-
-
20244381625
-
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
-
Kim, J. C. et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nature Genet. 36, 462-470 (2004). This is the first functional characterization of a Bardet-Biedl syndrome protein, BBS4, showing it to be involved in the transport of centrosomal proteins to the pericentriolar region in a dynein-dependent manner.
-
(2004)
Nature Genet.
, vol.36
, pp. 462-470
-
-
Kim, J.C.1
-
114
-
-
3042738924
-
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport
-
Blacque, O. E. et al. Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev. 18, 1630-1642 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 1630-1642
-
-
Blacque, O.E.1
-
115
-
-
0142104970
-
Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome
-
Ansley, S. J. et al. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 425, 628-633 (2003). Provides the first link between the pleiotropic phenotype of Bardet-Biedl syndrome with ciliary dysfunction.
-
(2003)
Nature
, vol.425
, pp. 628-633
-
-
Ansley, S.J.1
-
116
-
-
0037191046
-
Assembly of centrosomal proteins and microtubule organization depends on PCM-1
-
Dammermann, A. & Merdes, A. Assembly of centrosomal proteins and microtubule organization depends on PCM-1. J. Cell Biol. 159, 255-266 (2002).
-
(2002)
J. Cell Biol.
, vol.159
, pp. 255-266
-
-
Dammermann, A.1
Merdes, A.2
-
117
-
-
0033615982
-
Centriolar satellites: Molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis
-
Kubo, A., Sasaki, H., Yuba-Kubo, A., Tsukita, S. & Shiina, N. Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J. Cell Biol. 147, 969-979 (1999).
-
(1999)
J. Cell Biol.
, vol.147
, pp. 969-979
-
-
Kubo, A.1
Sasaki, H.2
Yuba-Kubo, A.3
Tsukita, S.4
Shiina, N.5
-
118
-
-
4143115620
-
Comparative genomic analysis identities an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3)
-
Chiang, A. P. et al. Comparative genomic analysis identities an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3). Am. J. Hum. Genet. 75, 475-484 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 475-484
-
-
Chiang, A.P.1
-
119
-
-
4444291840
-
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Hedl syndrome
-
Fan, Y. et al. Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Hedl syndrome. Nature Genet. 36, 989-993 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 989-993
-
-
Fan, Y.1
-
120
-
-
0035135929
-
Small GTP-binding proteins
-
Takai, Y, Sasaki, T. & Matozaki, T. Small GTP-binding proteins, Physiol. Rev. 81, 153-208 (2001).
-
(2001)
Physiol. Rev.
, vol.81
, pp. 153-208
-
-
Takai, Y.1
Sasaki, T.2
Matozaki, T.3
-
121
-
-
0036785149
-
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
-
Yoder B. K., Hou, X. & Guay-Woodford, L. M. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J. Am. Soc. Nephrol. 13, 2508-2516 (2002).
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2508-2516
-
-
Yoder, B.K.1
Hou, X.2
Guay-Woodford, L.M.3
-
122
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli, S. M. et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nature Genet 33, 129-137 (2003).
-
(2003)
Nature Genet.
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
-
123
-
-
0041592700
-
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
-
Otto, E. A. et al. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nature Genet. 34, 413-420 (2003).
-
(2003)
Nature Genet.
, vol.34
, pp. 413-420
-
-
Otto, E.A.1
-
124
-
-
0033825277
-
Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: The role of ninein
-
Mogensen, M. M., Malik, A., Piel, M., Bouckson-Castaing, V. & Bornens, M. Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein. J. Cell Sci. 113, 3013-3023 (2000).
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3013-3023
-
-
Mogensen, M.M.1
Malik, A.2
Piel, M.3
Bouckson-Castaing, V.4
Bornens, M.5
-
125
-
-
0034737302
-
Mechanisms of left-right determination in vertebrates
-
Capdevila, J., Vogan, K. J., Tabin, C. J. & Izpisúa Belmonte, J. C. Mechanisms of left-right determination in vertebrates. Cell 101, 9-21 (2000).
-
(2000)
Cell
, vol.101
, pp. 9-21
-
-
Capdevila, J.1
Vogan, K.J.2
Tabin, C.J.3
Izpisúa Belmonte, J.C.4
-
126
-
-
0036901166
-
Intraflagellar transport and cilia-dependent diseases
-
Pazour, G. J. & Rosenbaum, J. L. Intraflagellar transport and cilia-dependent diseases. Trends Cell Biol. 12, 551-555 (2002).
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 551-555
-
-
Pazour, G.J.1
Rosenbaum, J.L.2
-
127
-
-
0034735526
-
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
-
Pazour, G. J. et al. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J. Cell Biol. 151, 709-718 (2000).
-
(2000)
J. Cell Biol.
, vol.151
, pp. 709-718
-
-
Pazour, G.J.1
-
128
-
-
20144386878
-
MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis
-
in the press
-
Kim, J. C. et al. MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis. J. Cell Sci. (in the press).
-
J. Cell Sci.
-
-
Kim, J.C.1
-
129
-
-
0033577894
-
-/- mice analysis
-
-/- mice analysis. J. Cell Biol. 145, 825-636 (1999).
-
(1999)
J. Cell Biol.
, vol.145
, pp. 825-1636
-
-
Takeda, S.1
-
130
-
-
0344420336
-
LIS1 association with dynactin is required for nuclear motility and genomic union in the fertilized mammalian oocyte
-
Payne, C., St John, J. C., Ramalho-Santos, J. & Schatten, G. LIS1 association with dynactin is required for nuclear motility and genomic union in the fertilized mammalian oocyte. Cell Motil. Cytoskeleton 56, 245-251 (2003).
-
(2003)
Cell Motil. Cytoskeleton
, vol.56
, pp. 245-251
-
-
Payne, C.1
St John, J.C.2
Ramalho-Santos, J.3
Schatten, G.4
-
131
-
-
0037309808
-
Centrosome and spindle pole body dynamics. Review and abstracts of the EMBO/EMBL Conference on Centrosomes and Spindle Pole Bodies, Heidelberg, September 13-17,2002
-
Palazzo, R. E. Centrosome and spindle pole body dynamics. Review and abstracts of the EMBO/EMBL Conference on Centrosomes and Spindle Pole Bodies, Heidelberg, September 13-17,2002. Cell Motil. Cytoskeleton 54, 148-194 (2003).
-
(2003)
Cell Motil. Cytoskeleton
, vol.54
, pp. 148-194
-
-
Palazzo, R.E.1
-
132
-
-
0033559541
-
Histone ubiquitination and chromatin remodeling in mouse spermatogenesis
-
Baarends, W. M. et al. Histone ubiquitination and chromatin remodeling in mouse spermatogenesis. Dev. Biol. 207, 322-333 (1999).
-
(1999)
Dev. Biol.
, vol.207
, pp. 322-333
-
-
Baarends, W.M.1
-
133
-
-
0037774827
-
Ubiquitination of prohibitin in mammalian sperm mitochondria: Possible roles in the regulation of mitochondrial inheritance and sperm quality control
-
Thompson, W. E., Ramalho-Santos, J. & Sutovsky, P. Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control. Biol. Reprod. 69, 254-260 (2003).
-
(2003)
Biol. Reprod.
, vol.69
, pp. 254-260
-
-
Thompson, W.E.1
Ramalho-Santos, J.2
Sutovsky, P.3
-
134
-
-
0029760356
-
Two major autoantigen-antibody systems of the mitotic spindle apparatus
-
Andrade, L. E., Chan, E. K., Peebles, C. L. & Tan, E. M. Two major autoantigen-antibody systems of the mitotic spindle apparatus. Arthritis Rheum. 39, 1643-1653 (1996).
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 1643-1653
-
-
Andrade, L.E.1
Chan, E.K.2
Peebles, C.L.3
Tan, E.M.4
-
135
-
-
0028353367
-
PCM-1, a 228-kD centrosome autoantigen with a distinct cell cycle distribution
-
Balczon, R., Bao, L, & Zimmer, W. E. PCM-1, a 228-kD centrosome autoantigen with a distinct cell cycle distribution. J. Cell Biol. 124, 783-793 (1994).
-
(1994)
J. Cell Biol.
, vol.124
, pp. 783-793
-
-
Balczon, R.1
Bao, L.2
Zimmer, W.E.3
-
136
-
-
0019805796
-
Purine nucleoside phosphorylase is associated with centrioles and basal bodies
-
Oliver, J. M., Osborne, W. R., Pfeiffer, J. R., Child, F. M. & Berlin, R. D. Purine nucleoside phosphorylase is associated with centrioles and basal bodies. J. Cell Biol. 91, 837-847 (1981).
-
(1981)
J. Cell Biol.
, vol.91
, pp. 837-847
-
-
Oliver, J.M.1
Osborne, W.R.2
Pfeiffer, J.R.3
Child, F.M.4
Berlin, R.D.5
-
137
-
-
0031685161
-
Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient
-
Sasaki, Y. et al. Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient. Hum. Genet. 103, 81-85 (1998).
-
(1998)
Hum. Genet.
, vol.103
, pp. 81-85
-
-
Sasaki, Y.1
-
138
-
-
0036290509
-
Possible implication of Golgi-nucleating function for the centrosome
-
Takatsuki, A., Nakamura, M. & Kono, Y. Possible implication of Golgi-nucleating function for the centrosome. Biochem. Biophys. Res. Commun. 291, 494-500 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 494-500
-
-
Takatsuki, A.1
Nakamura, M.2
Kono, Y.3
-
139
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho, I. et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253, 665-669 (1991).
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
-
140
-
-
2342501364
-
Comparative genomic identification of conserved flagellar and basal body proteins that includes a novel gene for Bardet-Biedl syndrome
-
Li, J. B. et al. Comparative genomic identification of conserved flagellar and basal body proteins that includes a novel gene for Bardet-Biedl syndrome. Cell 117, 541-552 (2004).
-
(2004)
Cell
, vol.117
, pp. 541-552
-
-
Li, J.B.1
-
141
-
-
0034161335
-
FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cal myeloproliferative disorder with t(8;9)(p12;q33)
-
Guasch, G. et al. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cal myeloproliferative disorder with t(8;9)(p12;q33). Blood 95, 1788-1796 (2000).
-
(2000)
Blood
, vol.95
, pp. 1788-1796
-
-
Guasch, G.1
-
142
-
-
0031930213
-
Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome
-
Mack, G. J. et al. Autoantibodies to a group Of centrosomal proteins in human autoimmune sera reactive with the centrosome. Arthritis Rheum. 41, 551-558 (1998).
-
(1998)
Arthritis Rheum.
, vol.41
, pp. 551-558
-
-
Mack, G.J.1
-
143
-
-
0037184063
-
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity
-
Niwa, J. et al. Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity. J. Biol. Chem. 277, 36793-36798 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36793-36798
-
-
Niwa, J.1
-
144
-
-
1842562857
-
Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis
-
Takeuchi, H. et al. Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis. J. Neurochem. 89, 64-72 (2004).
-
(2004)
J. Neurochem.
, vol.89
, pp. 64-72
-
-
Takeuchi, H.1
-
145
-
-
0028219183
-
Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene
-
Engle, L. J. & Kennett, R. H. Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene. Genomes 19, 407-416 (1994).
-
(1994)
Genomes
, vol.19
, pp. 407-416
-
-
Engle, L.J.1
Kennett, R.H.2
-
146
-
-
0032555152
-
Localization of myosin-V in the centrosome
-
Espreafico, E. M. et al. Localization of myosin-V in the centrosome. Proc. Natl Acad. Sci. USA 95, 8636-8641 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8636-8641
-
-
Espreafico, E.M.1
-
147
-
-
0042388258
-
Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia
-
Arber, D. A. et al. Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia. Hum. Pathol. 34, 809-813 (2003).
-
(2003)
Hum. Pathol.
, vol.34
, pp. 809-813
-
-
Arber, D.A.1
-
148
-
-
0037333446
-
A poly(ADP-ribose) polymerase haplotype spanning the promoter region confers susceptibility to rheumatoid arthritis
-
Pascual, M. et al. A poly(ADP-ribose) polymerase haplotype spanning the promoter region confers susceptibility to rheumatoid arthritis. Arthritis Rheum. 48, 638-641 (2003).
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 638-641
-
-
Pascual, M.1
-
149
-
-
0242721664
-
Central role for the Wemer syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage
-
von Kobbe, C. et al. Central role for the Wemer syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage. Mol. Cell Biol. 23, 8601-8613 (2003).
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 8601-8613
-
-
Von Kobbe, C.1
-
150
-
-
0034738957
-
RET/PCM-1: A novel fusion gene in papillary thyroid carcinoma
-
Corvi, R., Berger, N., Balczon, R. & Romeo, G. RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma. Oncogene 19, 4236-4242 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 4236-4242
-
-
Corvi, R.1
Berger, N.2
Balczon, R.3
Romeo, G.4
-
151
-
-
0033778278
-
Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines
-
Simizu, S. & Osada, H. Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines. Nature Cell Biol. 2, 852-854 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 852-854
-
-
Simizu, S.1
Osada, H.2
-
152
-
-
0031715527
-
Organization, expression and polymorphism of the human persyn gene
-
Ninkina, N. N. et al. Organization, expression and polymorphism of the human persyn gene. Hum. Mol. Genet. 7, 1417-1424 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1417-1424
-
-
Ninkina, N.N.1
|