-
1
-
-
0031724471
-
WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: Involvement of the small GTPase RhoA
-
WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase RhoA. Mol. Cell. Biol. 18:6962-6970.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6962-6970
-
-
Adnane, J.1
Bizouarn, F.A.2
Qian, Y.3
Hamilton, A.D.4
Sebti, S.M.5
-
2
-
-
0029149885
-
Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site
-
Agnew, B. J., L. S. Minamide, and J. R. Bamburg. 1995. Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site. J. Biol. Chem. 270:17582-17587.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17582-17587
-
-
Agnew, B.J.1
Minamide, L.S.2
Bamburg, J.R.3
-
3
-
-
0031048791
-
Formation of actin stress fibers and focal adhesions enhanced by Rho kinase
-
Amano, M., K. Chihara, K. Kimura, Y. Fukata, N. Nakamura, Y. Matsuura, and K. Kaibuchi. 1997. Formation of actin stress fibers and focal adhesions enhanced by Rho kinase. Science 275:1308-1311.
-
(1997)
Science
, vol.275
, pp. 1308-1311
-
-
Amano, M.1
Chihara, K.2
Kimura, K.3
Fukata, Y.4
Nakamura, N.5
Matsuura, Y.6
Kaibuchi, K.7
-
4
-
-
0029786313
-
Phosphorylation and activation of myosin by Rho-associated kinase (Rho kinase)
-
Amano, M., M. Ito, K. Kimura, Y. Fukata, K. Chihara, T. Nakano, Y. Matsuura, and K. Kaibuchi. 1996. Phosphorylation and activation of myosin by Rho-associated kinase (Rho kinase). J. Biol. Chem. 271:20246-20249.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20246-20249
-
-
Amano, M.1
Ito, M.2
Kimura, K.3
Fukata, Y.4
Chihara, K.5
Nakano, T.6
Matsuura, Y.7
Kaibuchi, K.8
-
5
-
-
0033615525
-
Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin α chains
-
Aplin, A. E., S. M. Short, and R. L. Juliano. 1999. Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin α chains. J. Biol. Chem. 274:31223-31228.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31223-31228
-
-
Aplin, A.E.1
Short, S.M.2
Juliano, R.L.3
-
6
-
-
0032565962
-
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
-
Arber, S., F. A. Barbayannis, H. Hanser, C. Schneider, C. A. Stanyon, O. Bernard, and P. Caroni. 1998. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393:805-809.
-
(1998)
Nature
, vol.393
, pp. 805-809
-
-
Arber, S.1
Barbayannis, F.A.2
Hanser, H.3
Schneider, C.4
Stanyon, C.A.5
Bernard, O.6
Caroni, P.7
-
7
-
-
0032535711
-
INK4a-null mice
-
INK4a-null mice. Biochem. J. 336:551-560.
-
(1998)
Biochem. J.
, vol.336
, pp. 551-560
-
-
Auer, K.L.1
Park, J.S.2
Seth, P.3
Coffey, R.J.4
Darlington, G.5
Abo, A.6
McMahon, M.7
Depinho, R.A.8
Fisher, P.B.9
Dent, P.10
-
8
-
-
0034711221
-
Distinct roles of the adaptor protein She and focal adhesion kinase in integrin signaling to ERK
-
Barberis, L., K. K. Wary, G. Fiucci, F. Liu, E. Hirsch, M. Brancaccio, F. Altruda, G. Tarone, and F. G. Giancotti. 2000. Distinct roles of the adaptor protein She and focal adhesion kinase in integrin signaling to ERK. J. Biol. Chem. 275:36532-36540.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36532-36540
-
-
Barberis, L.1
Wary, K.K.2
Fiucci, G.3
Liu, F.4
Hirsch, E.5
Brancaccio, M.6
Altruda, F.7
Tarone, G.8
Giancotti, F.G.9
-
9
-
-
0030963016
-
Requirement for Rho in integrin signalling
-
Barry, S. T., H. M. Flinn, M. J. Humphries, D. R. Critchley, and A. J. Ridley. 1997. Requirement for Rho in integrin signalling. Cell Adhes. Commun. 4:387-398.
-
(1997)
Cell Adhes. Commun.
, vol.4
, pp. 387-398
-
-
Barry, S.T.1
Flinn, H.M.2
Humphries, M.J.3
Critchley, D.R.4
Ridley, A.J.5
-
10
-
-
0030028947
-
Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1
-
Bohmer, R. M., E. Scharf, and R. K. Assoian. 1996. Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1. Mol. Biol. Cell 7:101-111.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 101-111
-
-
Bohmer, R.M.1
Scharf, E.2
Assoian, R.K.3
-
11
-
-
0034769926
-
Distinct effects of mitogens and the actin cytoskeleton on CREB and pocket protein phosphorylation control the extent and timing of cyclin A promoter activity
-
Bottazzi, M. E., M. Buzzai, X. Zhu, C. Desdouets, C. Brechot, and R. K. Assoian. 2001. Distinct effects of mitogens and the actin cytoskeleton on CREB and pocket protein phosphorylation control the extent and timing of cyclin A promoter activity. Mol. Cell. Biol. 21:7607-7616.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7607-7616
-
-
Bottazzi, M.E.1
Buzzai, M.2
Zhu, X.3
Desdouets, C.4
Brechot, C.5
Assoian, R.K.6
-
12
-
-
0029731588
-
Focal adhesions, contractility, and signaling
-
Burridge, K., and M. Chrzanowska-Wodnicka. 1996. Focal adhesions, contractility, and signaling. Annu. Rev. Cell Dev. Biol. 12:463-518.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 463-518
-
-
Burridge, K.1
Chrzanowska-Wodnicka, M.2
-
14
-
-
0030953763
-
Geometric control of cell life and death
-
Chen, C. S., M. Mrksich, S. Huang, G. M. Whitesides, and D. E. Ingber. 1997. Geometric control of cell life and death. Science 276:1425-1428.
-
(1997)
Science
, vol.276
, pp. 1425-1428
-
-
Chen, C.S.1
Mrksich, M.2
Huang, S.3
Whitesides, G.M.4
Ingber, D.E.5
-
16
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka, M., and K. Burridge. 1996. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133:1403-1415.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
17
-
-
0032572557
-
Integrin-mediated signals regulated by members of the Rho family of GTPases
-
Clark, E. A., W. G. King, J. S. Brugge, M. Symons, and R. O. Hynes. 1998. Integrin-mediated signals regulated by members of the Rho family of GTPases. J. Cell Biol. 142:573-586.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 573-586
-
-
Clark, E.A.1
King, W.G.2
Brugge, J.S.3
Symons, M.4
Hynes, R.O.5
-
18
-
-
0037192630
-
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway
-
Coles, L. C., and P. E. Shaw. 2002. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. Oncogene 21:2236-2244.
-
(2002)
Oncogene
, vol.21
, pp. 2236-2244
-
-
Coles, L.C.1
Shaw, P.E.2
-
19
-
-
0034739844
-
Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression
-
Danen, E. H., P. Sonneveld, A. Sonnenberg, and K. M. Yamada. 2000. Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression. J. Cell Biol. 151:1413-1422.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1413-1422
-
-
Danen, E.H.1
Sonneveld, P.2
Sonnenberg, A.3
Yamada, K.M.4
-
20
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., H. Reddy, M. Caivano, and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95-105.
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
21
-
-
0018140371
-
Role of cell shape in growth control
-
Folkman, J., and A. Moscona. 1978. Role of cell shape in growth control. Nature 273:345-349.
-
(1978)
Nature
, vol.273
, pp. 345-349
-
-
Folkman, J.1
Moscona, A.2
-
22
-
-
0035903148
-
Fibroblast quiescence in floating or released collagen matrices: Contribution of the ERK signaling pathway and actin cytoskeletal organization
-
Fringer, J., and F. Grinnell. 2001. Fibroblast quiescence in floating or released collagen matrices: contribution of the ERK signaling pathway and actin cytoskeletal organization. J. Biol. Chem. 276:31047-31052.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31047-31052
-
-
Fringer, J.1
Grinnell, F.2
-
23
-
-
0030830220
-
Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
-
Frost, J. A., H. Steen, P. Shapiro, T. Lewis, N. Ahn, P. E. Shaw, and M. H. Cobb. 1997. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J. 16:6426-6438.
-
(1997)
EMBO J.
, vol.16
, pp. 6426-6438
-
-
Frost, J.A.1
Steen, H.2
Shapiro, P.3
Lewis, T.4
Ahn, N.5
Shaw, P.E.6
Cobb, M.H.7
-
24
-
-
0029741102
-
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
-
Gilmore, A. P., and L. H. Romer. 1996. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Biol. Cell 7:1209-1224.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 1209-1224
-
-
Gilmore, A.P.1
Romer, L.H.2
-
25
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
26
-
-
0032845724
-
Regulation of the hepatocyte cell cycle by type 1 collagen matrix: Role of cyclin D1
-
Hansen, L. K., and J. H. Albrecht. 1999. Regulation of the hepatocyte cell cycle by type 1 collagen matrix: role of cyclin D1. J. Cell Sci. 112:2971-2981.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 2971-2981
-
-
Hansen, L.K.1
Albrecht, J.H.2
-
28
-
-
0037193467
-
Defective Rac-mediated proliferation and survival after targeted mutation of the β1 integrin cytodomain
-
Hirsch, E., L. Barberis, M. Brancaccio, O. Azzolino, D. Xu, J. M. Kyriakis, L. Silengo, F. G. Giancotti, G. Tarone, R. Fassler, and F. Altruda. 2002. Defective Rac-mediated proliferation and survival after targeted mutation of the β1 integrin cytodomain. J. Cell Biol. 157:481-492.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 481-492
-
-
Hirsch, E.1
Barberis, L.2
Brancaccio, M.3
Azzolino, O.4
Xu, D.5
Kyriakis, J.M.6
Silengo, L.7
Giancotti, F.G.8
Tarone, G.9
Fassler, R.10
Altruda, F.11
-
29
-
-
0034282225
-
Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase
-
Howe, A. K., and R. L. Juliano. 2000. Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase. Nat. Cell Biol. 2:593-600.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 593-600
-
-
Howe, A.K.1
Juliano, R.L.2
-
30
-
-
0033525188
-
Kip1 degradation through its regulation of cyclin E/CDK2 activity
-
Kip1 degradation through its regulation of cyclin E/CDK2 activity. J. Biol. Chem. 274:3396-3401.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3396-3401
-
-
Hu, W.1
Bellone, C.J.2
Baldassare, J.J.3
-
31
-
-
0031739360
-
Kip1, and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension
-
Kip1, and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Mol. Biol. Cell 9:3179-3193.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3179-3193
-
-
Huang, S.1
Chen, C.S.2
Ingber, D.E.3
-
32
-
-
0036353562
-
1 that is cytoskeleton-dependent and MAP kinase (Erk) independent
-
1 that is cytoskeleton-dependent and MAP kinase (Erk) independent. Exp. Cell Res. 275:255-264.
-
(2002)
Exp. Cell Res.
, vol.275
, pp. 255-264
-
-
Huang, S.1
Ingber, D.E.2
-
33
-
-
0025372477
-
Fibronectin controls capillary endothelial cell growth by modulating cell shape
-
Ingber, D. E. 1990. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proc. Natl. Acad. Sci. USA 87:3579-3583.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3579-3583
-
-
Ingber, D.E.1
-
34
-
-
0034017744
-
Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases
-
Ishizaki, T., M. Uehata, I. Tamechika, J. Keel, K. Nonomura, M. Maekawa, and S. Narumiya. 2000. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol. Pharmacol. 57:976-983.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 976-983
-
-
Ishizaki, T.1
Uehata, M.2
Tamechika, I.3
Keel, J.4
Nonomura, K.5
Maekawa, M.6
Narumiya, S.7
-
35
-
-
0034118853
-
A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth
-
Iwamoto, H., M. Nakamuta, S. Tada, R. Sugimoto, M. Enjoji, and H. Nawata. 2000. A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth. J. Hepatol. 32:762-770.
-
(2000)
J. Hepatol.
, vol.32
, pp. 762-770
-
-
Iwamoto, H.1
Nakamuta, M.2
Tada, S.3
Sugimoto, R.4
Enjoji, M.5
Nawata, H.6
-
36
-
-
0019378350
-
Cell shape-mediated growth control of lens epithelial cells grown in culture
-
Iwig, M., D. Glaesser, and M. Bethge. 1981. Cell shape-mediated growth control of lens epithelial cells grown in culture. Exp. Cell Res. 131:47-55.
-
(1981)
Exp. Cell Res.
, vol.131
, pp. 47-55
-
-
Iwig, M.1
Glaesser, D.2
Bethge, M.3
-
37
-
-
0032860424
-
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
-
Kaibuchi, K., S. Kuroda, and M. Amano. 1999. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 68:459-486.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 459-486
-
-
Kaibuchi, K.1
Kuroda, S.2
Amano, M.3
-
38
-
-
0033615977
-
Phosphorylation of myosinbinding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
-
Kawano, Y., Y. Fukata, N. Oshiro, M. Amano, T. Nakamura, M. Ito, F. Matsumura, M. Inagaki, and K. Kaibuchi. 1999. Phosphorylation of myosinbinding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J. Cell Biol. 147:1023-1038.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1023-1038
-
-
Kawano, Y.1
Fukata, Y.2
Oshiro, N.3
Amano, M.4
Nakamura, T.5
Ito, M.6
Matsumura, F.7
Inagaki, M.8
Kaibuchi, K.9
-
39
-
-
0032511882
-
The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
-
King, A. J., H. Sun, B. Diaz, D. Barnard, W. Miao, S. Bagrodia, and M. S. Marshall. 1998. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature 396:180-183.
-
(1998)
Nature
, vol.396
, pp. 180-183
-
-
King, A.J.1
Sun, H.2
Diaz, B.3
Barnard, D.4
Miao, W.5
Bagrodia, S.6
Marshall, M.S.7
-
41
-
-
0035860701
-
Function of the Rho family GTPases in Ras-stimulated Raf activation
-
Li, W., H. Chong, and K. L. Guan. 2001. Function of the Rho family GTPases in Ras-stimulated Raf activation. J. Biol. Chem. 276:34728-34737.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34728-34737
-
-
Li, W.1
Chong, H.2
Guan, K.L.3
-
42
-
-
0031003237
-
Cell anchorage permits efficient signal transduction between ras and its downstream kinases
-
Lin, T. H., Q. Chen, A. Howe, and R. L. Juliano. 1997. Cell anchorage permits efficient signal transduction between ras and its downstream kinases. J. Biol. Chem. 272:8849-8852.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8849-8852
-
-
Lin, T.H.1
Chen, Q.2
Howe, A.3
Juliano, R.L.4
-
43
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
Maekawa, M., T. Ishizaki, S. Boku, N. Watanabe, A. Fujita, A. Iwamatsu, T. Obinata, K. Ohashi, K. Mizuno, and S. Narumiya. 1999. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285:895-898.
-
(1999)
Science
, vol.285
, pp. 895-898
-
-
Maekawa, M.1
Ishizaki, T.2
Boku, S.3
Watanabe, N.4
Fujita, A.5
Iwamatsu, A.6
Obinata, T.7
Ohashi, K.8
Mizuno, K.9
Narumiya, S.10
-
45
-
-
0028954797
-
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
-
Miyamoto, S., S. K. Akiyama, and K. M. Yamada. 1995. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 267:883-885.
-
(1995)
Science
, vol.267
, pp. 883-885
-
-
Miyamoto, S.1
Akiyama, S.K.2
Yamada, K.M.3
-
46
-
-
0030453194
-
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
-
Miyamoto, S., H. Teramoto, J. S. Gutkind, and K. M. Yamada. 1996. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol. 135:1633-1642.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1633-1642
-
-
Miyamoto, S.1
Teramoto, H.2
Gutkind, J.S.3
Yamada, K.M.4
-
47
-
-
0037088647
-
Cas and leads to phosphorylation of specific EGF receptor tyrosines
-
Cas and leads to phosphorylation of specific EGF receptor tyrosines. J. Biol. Chem. 277:9405-9414.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9405-9414
-
-
Moro, L.1
Dolce, L.2
Cabodi, S.3
Bergatto, E.4
Erba, E.B.5
Smeriglio, M.6
Turco, E.7
Retta, S.F.8
Giuffrida, M.G.9
Venturino, M.10
Godovac-Zimmermann, J.11
Conti, A.12
Schaefer, E.13
Beguinot, L.14
Tacchetti, C.15
Gaggini, P.16
Silengo, L.17
Tarone, G.18
Defilippi, P.19
-
48
-
-
0032538798
-
Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival
-
Moro, L., M. Venturino, C. Bozzo, L. Silengo, F. Altruda, L. Beguinot, G. Tarone, and P. Defilippi. 1998. Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO J. 17:6622-6632.
-
(1998)
EMBO J.
, vol.17
, pp. 6622-6632
-
-
Moro, L.1
Venturino, M.2
Bozzo, C.3
Silengo, L.4
Altruda, F.5
Beguinot, L.6
Tarone, G.7
Defilippi, P.8
-
49
-
-
0034602959
-
Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
-
Ohashi, K., K. Nagata, M. Maekawa, T. Ishizaki, S. Narumiya, and K. Mizuno. 2000. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J. Biol. Chem. 275:3577-3582.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3577-3582
-
-
Ohashi, K.1
Nagata, K.2
Maekawa, M.3
Ishizaki, T.4
Narumiya, S.5
Mizuno, K.6
-
52
-
-
0037178873
-
MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway
-
Pawlak, G., and D. M. Helfman. 2002. MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway. J. Biol. Chem. 277:26927-26933.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26927-26933
-
-
Pawlak, G.1
Helfman, D.M.2
-
53
-
-
0036156469
-
Post-transcriptional downregulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts
-
Pawlak, G., and D. M. Helfman. 2002. Post-transcriptional downregulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts. Mol. Biol. Cell 13:336-347.
-
(2002)
Mol. Biol. Cell.
, vol.13
, pp. 336-347
-
-
Pawlak, G.1
Helfman, D.M.2
-
55
-
-
0033081753
-
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
-
Ren, X. D., W. B. Kiosses, and M. A. Schwartz. 1999. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18:578-585.
-
(1999)
EMBO J.
, vol.18
, pp. 578-585
-
-
Ren, X.D.1
Kiosses, W.B.2
Schwartz, M.A.3
-
56
-
-
0033229747
-
Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
-
Renshaw, M. W., L. S. Price, and M. A. Schwartz. 1999. Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase. J. Cell Biol. 147:611-618.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 611-618
-
-
Renshaw, M.W.1
Price, L.S.2
Schwartz, M.A.3
-
57
-
-
0030766846
-
Growth factor activation of MAP kinase requires cell adhesion
-
Renshaw, M. W., X. D. Ren, and M. A. Schwartz. 1997. Growth factor activation of MAP kinase requires cell adhesion. EMBO J. 16:5592-5599.
-
(1997)
EMBO J.
, vol.16
, pp. 5592-5599
-
-
Renshaw, M.W.1
Ren, X.D.2
Schwartz, M.A.3
-
59
-
-
0030694182
-
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
-
Richardson, A., R. K. Malik, J. D. Hildebrand, and J. T. Parsons. 1997. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Mol. Cell. Biol. 17:6906-6914.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6906-6914
-
-
Richardson, A.1
Malik, R.K.2
Hildebrand, J.D.3
Parsons, J.T.4
-
61
-
-
0032589393
-
α5β1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells
-
Roovers, K., G. Davey, X. Zhu, M. E. Bottazzi, and R. K. Assoian. 1999. α5β1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells. Mol. Biol. Cell 10:3197-3204.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 3197-3204
-
-
Roovers, K.1
Davey, G.2
Zhu, X.3
Bottazzi, M.E.4
Assoian, R.K.5
-
62
-
-
0034603082
-
Fibroblast quiescence and the disruption of ERK signaling in mechanically unloaded collagen matrices
-
Rosenfeldt, H., and F. Grinnell. 2000. Fibroblast quiescence and the disruption of ERK signaling in mechanically unloaded collagen matrices. J. Biol. Chem. 275:3088-3092.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3088-3092
-
-
Rosenfeldt, H.1
Grinnell, F.2
-
63
-
-
0033545354
-
Transformation mediated by RhoA requires activity of ROCK kinases
-
Sahai, E., T. Ishizaki, S. Narumiya, and R. Treisman. 1999. Transformation mediated by RhoA requires activity of ROCK kinases. Curr. Biol. 9:136-145.
-
(1999)
Curr. Biol.
, vol.9
, pp. 136-145
-
-
Sahai, E.1
Ishizaki, T.2
Narumiya, S.3
Treisman, R.4
-
64
-
-
0035865137
-
Cross-talk between Ras and Rho signalling pathways in transformation favors proliferation and increased motility
-
Sahai, E., M. F. Olson, and C. J. Marshall. 2001. Cross-talk between Ras and Rho signalling pathways in transformation favors proliferation and increased motility. EMBO J. 20:755-766.
-
(2001)
EMBO J.
, vol.20
, pp. 755-766
-
-
Sahai, E.1
Olson, M.F.2
Marshall, C.J.3
-
65
-
-
0023644877
-
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase
-
Saitoh, M., T. Ishikawa, S. Matsushima, M. Naka, and H. Hidaka. 1987. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J. Biol. Chem. 262:7796-7801.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7796-7801
-
-
Saitoh, M.1
Ishikawa, T.2
Matsushima, S.3
Naka, M.4
Hidaka, H.5
-
66
-
-
0342314481
-
Inhibition of Rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries
-
Sawada, N., H. Itoh, K. Ueyama, J. Yamashita, K. Doi, T. H. Chun, M. Inoue, K. Masatsugu, T. Saito, Y. Fukunaga, S. Sakaguchi, H. Arai, N. Ohno, M. Komeda, and K. Nakao. 2000. Inhibition of Rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation 101:2030-2033.
-
(2000)
Circulation
, vol.101
, pp. 2030-2033
-
-
Sawada, N.1
Itoh, H.2
Ueyama, K.3
Yamashita, J.4
Doi, K.5
Chun, T.H.6
Inoue, M.7
Masatsugu, K.8
Saito, T.9
Fukunaga, Y.10
Sakaguchi, S.11
Arai, H.12
Ohno, N.13
Komeda, M.14
Nakao, K.15
-
67
-
-
0030814976
-
αVβ3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF
-
Schneller, M., K. Vuori, and E. Ruoslahti. 1997. αVβ3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF. EMBO J. 16:5600-5607.
-
(1997)
EMBO J.
, vol.16
, pp. 5600-5607
-
-
Schneller, M.1
Vuori, K.2
Ruoslahti, E.3
-
69
-
-
0032895264
-
Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle
-
Tang, D., D. Mehta, and S. J. Gunst. 1999. Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle. Am. J. Physiol. 276:C250-C258.
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Tang, D.1
Mehta, D.2
Gunst, S.J.3
-
70
-
-
0036277026
-
Myofibroblasts and mechano-regulation of connective tissue remodeling
-
Tomasek, J. J., G. Gabbiani, B. Hinz, C. Chaponnier, and R. A. Brown. 2002. Myofibroblasts and mechano-regulation of connective tissue remodeling. Nat. Rev. Mol. Cell. Biol. 3:349-363.
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
71
-
-
0034698841
-
Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts
-
Totsukawa, G., Y. Yamakita, S. Yamashiro, D. J. Hartshorne, Y. Sasaki, and F. Matsumura. 2000. Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J. Cell Biol. 150:797-806.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 797-806
-
-
Totsukawa, G.1
Yamakita, Y.2
Yamashiro, S.3
Hartshorne, D.J.4
Sasaki, Y.5
Matsumura, F.6
-
72
-
-
0035808419
-
Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase
-
Sumi, T., K. Matsumoto, and T. Nakamura. 2001. Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase. J. Biol. Chem. 276:670-676.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 670-676
-
-
Sumi, T.1
Matsumoto, K.2
Nakamura, T.3
-
73
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst, L., and C. D'Souza-Schorey. 1997. Rho GTPases and signaling networks. Genes Dev. 11:2295-2322.
-
(1997)
Genes Dev.
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
74
-
-
0030584077
-
The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
-
Wary, K. K., F. Mainiero, S. J. Isakoff, E. E. Marcantonio, and F. G. Giancotti. 1996. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 87:733-743.
-
(1996)
Cell
, vol.87
, pp. 733-743
-
-
Wary, K.K.1
Mainiero, F.2
Isakoff, S.J.3
Marcantonio, E.E.4
Giancotti, F.G.5
-
75
-
-
0032483575
-
A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
-
Wary, K. K., A. Mariotti, C. Zurzolo, and F. G. Giancotti. 1998. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94:625-634.
-
(1998)
Cell
, vol.94
, pp. 625-634
-
-
Wary, K.K.1
Mariotti, A.2
Zurzolo, C.3
Giancotti, F.G.4
-
78
-
-
0020515736
-
Factors influencing the expression of stress fibers in vascular endothelial cells in situ
-
White, G. E., M. A. Gimbrone, Jr., and K. Fujiwara. 1983. Factors influencing the expression of stress fibers in vascular endothelial cells in situ. J. Cell Biol. 97:416-424.
-
(1983)
J. Cell Biol.
, vol.97
, pp. 416-424
-
-
White, G.E.1
Gimbrone M.A., Jr.2
Fujiwara, K.3
-
79
-
-
0020664146
-
Actin filament stress fibers in vascular endothelial cells in vivo
-
Wong, A. J., T. D. Pollard, and I. M. Herman. 1983. Actin filament stress fibers in vascular endothelial cells in vivo. Science 219:867-869.
-
(1983)
Science
, vol.219
, pp. 867-869
-
-
Wong, A.J.1
Pollard, T.D.2
Herman, I.M.3
-
80
-
-
0032565769
-
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
-
Yang, N., O. Higuchi, K. Ohashi, K. Nagata, A. Wada, K. Kangawa, E. Nishida, and K. Mizuno. 1998. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393:809-812.
-
(1998)
Nature
, vol.393
, pp. 809-812
-
-
Yang, N.1
Higuchi, O.2
Ohashi, K.3
Nagata, K.4
Wada, A.5
Kangawa, K.6
Nishida, E.7
Mizuno, K.8
-
81
-
-
0030210726
-
FAK and paxillin in aortic endothelial cells induced by mechanical strain
-
FAK and paxillin in aortic endothelial cells induced by mechanical strain. Am. J. Physiol. 271:C635-C649.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Yano, Y.1
Geibel, J.2
Sumpio, B.E.3
-
82
-
-
0037040291
-
Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1
-
Zang, M., C. Hayne, and Z. Luo. 2002. Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1. J. Biol. Chem. 277:4395-4405.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4395-4405
-
-
Zang, M.1
Hayne, C.2
Luo, Z.3
-
83
-
-
0035661624
-
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
-
Zhao, J., R. Pestell, and J. L. Guan. 2001. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Mol. Biol. Cell 12:4066-4077.
-
(2001)
Mol. Biol. Cell.
, vol.12
, pp. 4066-4077
-
-
Zhao, J.1
Pestell, R.2
Guan, J.L.3
-
84
-
-
0032576547
-
Regulation of the cell cycle by focal adhesion kinase
-
Zhao, J. H., H. Reiske, and J. L. Guan. 1998. Regulation of the cell cycle by focal adhesion kinase. J. Cell Biol. 143:1997-2008.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1997-2008
-
-
Zhao, J.H.1
Reiske, H.2
Guan, J.L.3
-
85
-
-
0029876639
-
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
-
Zhu, X., M. Ohtsubo, R. M. Bohmer, J. M. Roberts, and R. K. Assoian. 1996. Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol. 133:391-403.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 391-403
-
-
Zhu, X.1
Ohtsubo, M.2
Bohmer, R.M.3
Roberts, J.M.4
Assoian, R.K.5
|