Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness

Clinical Cancer Research

Volumn 12, Issue 4, 2006, Pages 1080-1087

  Jokilehto, Terhi ^a,b,c   Rantanen, Krista ^a,b   Luukkaa, Marjaana ^c   Heikkinen, Pekka ^a,b   Grenman, Reidar ^c   Minn, Heikki ^c   Kronqvist, Pauliina ^c   Jaakkola, Panu M ^a,b  

^a TURKU CENTRE FOR BIOTECHNOLOGY   (Finland)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MESSENGER RNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE PHD2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER INVASION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ENDOTHELIUM CELL; FEMALE; GENE OVEREXPRESSION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN TARGETING; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME;

ACTIVE TRANSPORT, CELL NUCLEUS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CELL LINE; CELL NUCLEUS; DIOXYGENASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HEAD AND NECK NEOPLASMS; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MICROSCOPY, CONFOCAL; NEOPLASM INVASIVENESS; PROCOLLAGEN-PROLINE DIOXYGENASE; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 33644781737     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-2022     Document Type: Article

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