Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

Biochemical Journal

Volumn 380, Issue 2, 2004, Pages 419-424

  Dalgard, Clifton Lee ^a   Lu, Huasheng ^a   Mohyeldin, Ahmed ^a   Verma, Ajay ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Hypoxia; Hypoxia inducible factor (HIF); Oxaloacetate; Oxygen sensor; Prolyl hydroxylase; Pyruvate

Indexed keywords

CARBOXYLIC ACIDS; DISEASES; ENZYMES; FEEDBACK; GENES; GENETIC ENGINEERING; OXYGEN SENSORS;

2-OXOACIDS; GLYCOLYSIS; HETERODIMERIC TRANSCRIPTION FACTORS; MULTI-CELLULAR ORGANIZMS;

OXYGEN;

2 OXOACID; ASPARTIC ACID; HYPOXIA INDUCIBLE FACTOR 1; OXALOACETIC ACID; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PYRUVIC ACID; TRICARBOXYLIC ACID;

ARTICLE; BIOSENSOR; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GLUCONEOGENESIS; GLYCOLYSIS; HOMEOSTASIS; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; UPREGULATION;

ANOXIA; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM NEOPLASMS; CITRIC ACID CYCLE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLIOBLASTOMA; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETO ACIDS; MIXED FUNCTION OXYGENASES; NUCLEAR PROTEINS; OXALOACETATE; OXYGEN; PYRUVIC ACID; TRANSCRIPTION FACTORS;

CELLULAR ORGANISMS;

EID: 2642542967     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031647     Document Type: Article

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