Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 7919-7926

  Gardner, Lawrence B ^a,b   Li, Qing ^c   Park, Michele S ^d   Flanagan, W Michael ^f,g   Semenza, Gregg L ^e   Dang, Chi V ^a,b,c,h  

^a Department of Medicine ^*  (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Molecule and Cell Engineering   (United States)

^d Weill Cornell Graduate School of Biomedical Sciences   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f GILEAD SCIENCES   (United States)

^g Sunesis Pharmaceuticals Inc   (United States)

^h Departments of Pediatrics Medicine Oncology and Radiation Oncology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; METABOLISM; PROTEINS; REDUCTION;

EMBRYO FIBROBLASTS; HYPOPHOSPHORYLATION;

GENETIC ENGINEERING;

CYCLIN DEPENDENT KINASE 2; OXYGEN; PROTEIN P21; PROTEIN P27; PROTEIN P53; CDK2 PROTEIN, MOUSE; CDK2 PROTEIN, RAT; CDKN1B PROTEIN, MOUSE; CDKN1B PROTEIN, RAT; CELL CYCLE PROTEIN; CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; DNA BINDING PROTEIN; HIF1A PROTEIN, MOUSE; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICROTUBULE ASSOCIATED PROTEIN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL HYPOXIA; CELL PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; PHYSIOLOGY; PROMOTER REGION;

ANIMALIA; MAMMALIA; MURINAE;

ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL HYPOXIA; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA-BINDING PROTEINS; G1 PHASE; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; RATS; S PHASE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0035896558     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010189200     Document Type: Article

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