-
1
-
-
0035888074
-
Estimating the world cancer burden: Globocan 2000
-
D.M. Parkin F. Bray J. Ferlay et al. Estimating the world cancer burden: Globocan 2000 Int J Cancer 94 2001 153-156
-
(2001)
Int J Cancer
, vol.94
, pp. 153-156
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
-
2
-
-
0036742628
-
Epidemiology and clinical presentation of hepatocellular carcinoma
-
A.M. Di Bisceglie Epidemiology and clinical presentation of hepatocellular carcinoma J Vasc Interv Radiol 13 2002 S169-S171
-
(2002)
J Vasc Interv Radiol
, vol.13
-
-
Di Bisceglie, A.M.1
-
3
-
-
0036189111
-
Prognostic prediction and treatment strategy in hepatocellular carcinoma
-
J. Bruix J.M. Llovet Prognostic prediction and treatment strategy in hepatocellular carcinoma Hepatology 35 2002 519-524
-
(2002)
Hepatology
, vol.35
, pp. 519-524
-
-
Bruix, J.1
Llovet, J.M.2
-
4
-
-
7044231396
-
Hepatocellular carcinoma: Recent trends in the United States
-
H.B. El-Serag Hepatocellular carcinoma: Recent trends in the United States Gastroenterology 127 2004 S27-S34
-
(2004)
Gastroenterology
, vol.127
-
-
El-Serag, H.B.1
-
5
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
H.B. El-Serag A.C. Mason Rising incidence of hepatocellular carcinoma in the United States N Engl J Med 340 1999 745-750
-
(1999)
N Engl J Med
, vol.340
, pp. 745-750
-
-
El-Serag, H.B.1
Mason, A.C.2
-
6
-
-
0141828970
-
Mechanisms of human hepatocarcinogenesis
-
W.B. Coleman Mechanisms of human hepatocarcinogenesis Curr Mol Med 3 2003 573-588
-
(2003)
Curr Mol Med
, vol.3
, pp. 573-588
-
-
Coleman, W.B.1
-
7
-
-
17044453428
-
Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma
-
M. Kondo H. Yamamoto H. Nagano et al. Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma Clin Cancer Res 5 1999 4005-4012
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4005-4012
-
-
Kondo, M.1
Yamamoto, H.2
Nagano, H.3
-
8
-
-
0032978469
-
Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation
-
H. Koga S. Sakisaka M. Ohishi et al. Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation Hepatology 29 1999 688-696
-
(1999)
Hepatology
, vol.29
, pp. 688-696
-
-
Koga, H.1
Sakisaka, S.2
Ohishi, M.3
-
9
-
-
0033063736
-
Cyclooxygenase-2 expression in hepatocellular carcinoma
-
G. Shiota M. Okubo T. Noumi et al. Cyclooxygenase-2 expression in hepatocellular carcinoma Hepatogastroenterology 46 1999 407-412
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 407-412
-
-
Shiota, G.1
Okubo, M.2
Noumi, T.3
-
10
-
-
0034905269
-
Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
-
S.H. Bae E.S. Jung Y.M. Park et al. Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398 Clin Cancer Res 7 2001 1410-1418
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1410-1418
-
-
Bae, S.H.1
Jung, E.S.2
Park, Y.M.3
-
11
-
-
0034906314
-
Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: Possible involvement of COX-2 in the angiogenesis of hepatitis C virus-positive cases
-
M.A. Rahman D.K. Dhar E. Yamaguchi et al. Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: Possible involvement of COX-2 in the angiogenesis of hepatitis C virus-positive cases Clin Cancer Res 7 2001 1325-1332
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1325-1332
-
-
Rahman, M.A.1
Dhar, D.K.2
Yamaguchi, E.3
-
12
-
-
0041822007
-
Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis
-
J. Leng C. Han A.J. Demetris et al. Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis Hepatology 38 2003 756-768
-
(2003)
Hepatology
, vol.38
, pp. 756-768
-
-
Leng, J.1
Han, C.2
Demetris, A.J.3
-
13
-
-
1842852639
-
Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma
-
A.S. Cheng H.L. Chan K.F. et al. To Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma Int J Oncol 24 2004 853-860
-
(2004)
Int J Oncol
, vol.24
, pp. 853-860
-
-
Cheng, A.S.1
Chan, H.L.2
To, K.F.3
-
14
-
-
0023901609
-
Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia
-
T. Ikeda S. Tozuka Y. Hasumura et al. Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia Cancer 61 1988 1813-1814
-
(1988)
Cancer
, vol.61
, pp. 1813-1814
-
-
Ikeda, T.1
Tozuka, S.2
Hasumura, Y.3
-
15
-
-
33644898889
-
1 transactivates EGFR/ Met receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells
-
[in press]
-
1 transactivates EGFR/Met receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. J Cell Physiol [in press].
-
J Cell Physiol
-
-
Han, C.1
Michalopoulos, G.2
Wu, T.3
-
16
-
-
0018372427
-
Evidence that indomethacin reversibly inhibits cell growth in the G1 phase of the cell cycle
-
B.M. Bayer M.A. Beaven Evidence that indomethacin reversibly inhibits cell growth in the G1 phase of the cell cycle Biochem Pharmacol 28 1979 441-443
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 441-443
-
-
Bayer, B.M.1
Beaven, M.A.2
-
17
-
-
0036788542
-
Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells
-
M.A. Kern D. Schubert D. Sahi et al. Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells Hepatology 36 2002 885-894
-
(2002)
Hepatology
, vol.36
, pp. 885-894
-
-
Kern, M.A.1
Schubert, D.2
Sahi, D.3
-
18
-
-
0036280432
-
Effect of nimesulide on proliferation and apoptosis of human hepatoma SMMC-7721 cells
-
G. Tian J.P. Yu H.S. Luo et al. Effect of nimesulide on proliferation and apoptosis of human hepatoma SMMC-7721 cells World J Gastroenterol 8 2002 483-487
-
(2002)
World J Gastroenterol
, vol.8
, pp. 483-487
-
-
Tian, G.1
Yu, J.P.2
Luo, H.S.3
-
19
-
-
0042198296
-
Inhibited proliferation of cyclooxygenase-2 expressing human hepatoma cells by NS-398, a selective COX-2 inhibitor
-
K.Q. Hu C.H. Yu Y. Mineyama et al. Inhibited proliferation of cyclooxygenase-2 expressing human hepatoma cells by NS-398, a selective COX-2 inhibitor Int J Oncol 22 2003 757-763
-
(2003)
Int J Oncol
, vol.22
, pp. 757-763
-
-
Hu, K.Q.1
Yu, C.H.2
Mineyama, Y.3
-
20
-
-
14944386105
-
Induction of Apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors
-
D. Fodera N. D'Alessandro A. Cusimano et al. Induction of Apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors Ann N Y Acad Sci 1028 2004 440-449
-
(2004)
Ann N Y Acad Sci
, vol.1028
, pp. 440-449
-
-
Fodera, D.1
D'lessandro, N.2
Cusimano, A.3
-
21
-
-
4344593795
-
NS398 inhibits the growth of Hep3B human hepatocellular carcinoma cells via caspase-independent apoptosis
-
M.K. Park S.Y. Hwang J.O. Kim et al. NS398 inhibits the growth of Hep3B human hepatocellular carcinoma cells via caspase-independent apoptosis Mol Cells 17 2004 45-50
-
(2004)
Mol Cells
, vol.17
, pp. 45-50
-
-
Park, M.K.1
Hwang, S.Y.2
Kim, J.O.3
-
22
-
-
12344272682
-
Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2
-
D.S. Huang K.Z. Shen J.F. Wei et al. Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2 World J Gastroenterol 11 2005 204-207
-
(2005)
World J Gastroenterol
, vol.11
, pp. 204-207
-
-
Huang, D.S.1
Shen, K.Z.2
Wei, J.F.3
-
23
-
-
0036100517
-
NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines
-
J. Cheng H. Imanishi Y. Amuro et al. NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines Int J Cancer 99 2002 755-761
-
(2002)
Int J Cancer
, vol.99
, pp. 755-761
-
-
Cheng, J.1
Imanishi, H.2
Amuro, Y.3
-
24
-
-
0029976175
-
Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, l-amino acid-defined diet in rats
-
T. Endoh Q. Tang A. Denda et al. Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, l -amino acid-defined diet in rats Carcinogenesis 17 1996 467-475
-
(1996)
Carcinogenesis
, vol.17
, pp. 467-475
-
-
Endoh, T.1
Tang, Q.2
Denda, A.3
-
25
-
-
0028287952
-
Prevention by acetylsalicylic acid of liver cirrhosis and carcinogenesis as well as generations of 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances caused by a choline-deficient, l-amino acid-defined diet in rats
-
A. Denda Q. Tang T. Endoh et al. Prevention by acetylsalicylic acid of liver cirrhosis and carcinogenesis as well as generations of 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances caused by a choline-deficient, l -amino acid-defined diet in rats Carcinogenesis 15 1994 1279-1283
-
(1994)
Carcinogenesis
, vol.15
, pp. 1279-1283
-
-
Denda, A.1
Tang, Q.2
Endoh, T.3
-
26
-
-
0032543384
-
Prevention by inhibitors of arachidonic acid cascade of liver carcinogenesis, cirrhosis and oxidative DNA damage caused by a choline-deficient, l-amino acid-defined diet in rats
-
A. Denda T. Endoh Q. Tang et al. Prevention by inhibitors of arachidonic acid cascade of liver carcinogenesis, cirrhosis and oxidative DNA damage caused by a choline-deficient, l -amino acid-defined diet in rats Mutat Res 402 1998 279-288
-
(1998)
Mutat Res
, vol.402
, pp. 279-288
-
-
Denda, A.1
Endoh, T.2
Tang, Q.3
-
27
-
-
0024326041
-
Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis
-
A. Denda H. Ura T. Tsujiuchi et al. Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis Carcinogenesis 10 1989 1929-1935
-
(1989)
Carcinogenesis
, vol.10
, pp. 1929-1935
-
-
Denda, A.1
Ura, H.2
Tsujiuchi, T.3
-
28
-
-
0027536463
-
Inhibitory effect of the non-steroidal anti-inflammatory drugs, indomethacin and piroxicam on 2-acetylaminofluorene-induced hepatocarcinogenesis in male ACI/N rats
-
T. Tanaka T. Kojima A. Okumura et al. Inhibitory effect of the non-steroidal anti-inflammatory drugs, indomethacin and piroxicam on 2-acetylaminofluorene-induced hepatocarcinogenesis in male ACI/N rats Cancer Lett 68 1993 111-118
-
(1993)
Cancer Lett
, vol.68
, pp. 111-118
-
-
Tanaka, T.1
Kojima, T.2
Okumura, A.3
-
29
-
-
0024383951
-
Elevated levels of prostaglandin E2 in the liver of rats fed a choline deficient diet: Possible involvement in liver tumor promotion
-
C. Gupta M. Banks H. Shinozuka Elevated levels of prostaglandin E2 in the liver of rats fed a choline deficient diet: Possible involvement in liver tumor promotion Cancer Lett 46 1989 129-135
-
(1989)
Cancer Lett
, vol.46
, pp. 129-135
-
-
Gupta, C.1
Banks, M.2
Shinozuka, H.3
-
30
-
-
3242809061
-
Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice
-
M.A. Kern M.M. Schoneweiss D. Sahi et al. Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice Carcinogenesis 25 2004 1193-1199
-
(2004)
Carcinogenesis
, vol.25
, pp. 1193-1199
-
-
Kern, M.A.1
Schoneweiss, M.M.2
Sahi, D.3
-
31
-
-
24344500895
-
Celecoxib, a cyclooxygenase-2 inhibitor, prevents induction of liver preneoplastic lesions in rats
-
L. Marquez-Rosado M.C. Trejo-Solis C.M. Garcia-Cuellar et al. Celecoxib, a cyclooxygenase-2 inhibitor, prevents induction of liver preneoplastic lesions in rats J Hepatol 43 2005 653-660
-
(2005)
J Hepatol
, vol.43
, pp. 653-660
-
-
Marquez-Rosado, L.1
Trejo-Solis, M.C.2
Garcia-Cuellar, C.M.3
-
32
-
-
0028338536
-
Diversity of group types, regulation, and function of phospholipase A2
-
E.A. Dennis Diversity of group types, regulation, and function of phospholipase A2 J Biol Chem 269 1994 13057-13060
-
(1994)
J Biol Chem
, vol.269
, pp. 13057-13060
-
-
Dennis, E.A.1
-
33
-
-
0030614354
-
The growing phospholipase A2 superfamily of signal transduction enzymes
-
E.A. Dennis The growing phospholipase A2 superfamily of signal transduction enzymes Trends Biochem Sci 22 1997 1-2
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 1-2
-
-
Dennis, E.A.1
-
35
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
R.N. Dubois S.B. Abramson L. Crofford et al. Cyclooxygenase in biology and disease FASEB J 12 1998 1063-1073
-
(1998)
FASEB J
, vol.12
, pp. 1063-1073
-
-
Dubois, R.N.1
Abramson, S.B.2
Crofford, L.3
-
36
-
-
0035235121
-
Cox-2-specific inhibitors: Definition of a new therapeutic concept
-
K.M. Verburg T.J. Maziasz E. Weiner et al. Cox-2-specific inhibitors: definition of a new therapeutic concept Am J Ther 8 2001 49-64
-
(2001)
Am J Ther
, vol.8
, pp. 49-64
-
-
Verburg, K.M.1
Maziasz, T.J.2
Weiner, E.3
-
37
-
-
0034676492
-
A causal relationship between unscheduled eicosanoid signaling and tumor development: Cancer chemoprevention by inhibitors of arachidonic acid metabolism
-
F. Marks K. Muller-Decker G. Furstenberger A causal relationship between unscheduled eicosanoid signaling and tumor development: Cancer chemoprevention by inhibitors of arachidonic acid metabolism Toxicology 153 2000 11-26
-
(2000)
Toxicology
, vol.153
, pp. 11-26
-
-
Marks, F.1
Muller-Decker, K.2
Furstenberger, G.3
-
38
-
-
0034471496
-
Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia
-
E. Fosslien Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia Crit Rev Clin Lab Sci 37 2000 431-502
-
(2000)
Crit Rev Clin Lab Sci
, vol.37
, pp. 431-502
-
-
Fosslien, E.1
-
39
-
-
0033655574
-
COX-2 and colon cancer: Potential targets for chemoprevention
-
D.B. Fournier G.B. Gordon COX-2 and colon cancer: Potential targets for chemoprevention J Cell Biochem Suppl. 34 2000 97-102
-
(2000)
J Cell Biochem
, Issue.SUPPL. 34
, pp. 97-102
-
-
Fournier, D.B.1
Gordon, G.B.2
-
40
-
-
0034530889
-
The contributions of cyclooxygenase-2 to tumor angiogenesis
-
S. Gately The contributions of cyclooxygenase-2 to tumor angiogenesis Cancer Metastasis Rev 19 2000 19-27
-
(2000)
Cancer Metastasis Rev
, vol.19
, pp. 19-27
-
-
Gately, S.1
-
41
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer, and development
-
C.S. Williams M. Mann R.N. DuBois The role of cyclooxygenases in inflammation, cancer, and development Oncogene 18 1999 7908-7916
-
(1999)
Oncogene
, vol.18
, pp. 7908-7916
-
-
Williams, C.S.1
Mann, M.2
DuBois, R.N.3
-
42
-
-
0034993850
-
Regulated formation of eicosanoids
-
F.A. Fitzpatrick R. Soberman Regulated formation of eicosanoids J Clin Invest 107 2001 1347-1351
-
(2001)
J Clin Invest
, vol.107
, pp. 1347-1351
-
-
Fitzpatrick, F.A.1
Soberman, R.2
-
43
-
-
0034971264
-
Why there are two cyclooxygenase isozymes
-
W.L. Smith R. Langenbach Why there are two cyclooxygenase isozymes J Clin Invest 107 2001 1491-1495
-
(2001)
J Clin Invest
, vol.107
, pp. 1491-1495
-
-
Smith, W.L.1
Langenbach, R.2
-
44
-
-
0033791318
-
Cyclooxygenases: Structural, cellular, and molecular biology
-
W.L. Smith D.L. DeWitt R.M. Garavito Cyclooxygenases: Structural, cellular, and molecular biology Annu Rev Biochem 69 2000 145-182
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 145-182
-
-
Smith, W.L.1
DeWitt, D.L.2
Garavito, R.M.3
-
45
-
-
0035496616
-
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
-
R.A. Gupta R.N. Dubois Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 Nat Rev Cancer 1 2001 11-21
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 11-21
-
-
Gupta, R.A.1
Dubois, R.N.2
-
46
-
-
4143107932
-
Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
-
D.L. Simmons R.M. Botting T. Hla Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition Pharmacol Rev 56 2004 387-437
-
(2004)
Pharmacol Rev
, vol.56
, pp. 387-437
-
-
Simmons, D.L.1
Botting, R.M.2
Hla, T.3
-
47
-
-
0031919154
-
Molecular mechanisms of prostaglandin transport
-
V.L. Schuster Molecular mechanisms of prostaglandin transport Annu Rev Physiol 60 1998 221-242
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 221-242
-
-
Schuster, V.L.1
-
48
-
-
0035468642
-
Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer
-
A.J. Dannenberg N.K. Altorki J.O. Boyle et al. Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer Lancet Oncol 2 2001 544-551
-
(2001)
Lancet Oncol
, vol.2
, pp. 544-551
-
-
Dannenberg, A.J.1
Altorki, N.K.2
Boyle, J.O.3
-
49
-
-
0141963117
-
Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents?
-
G. Gasparini R. Longo R. Sarmiento et al. Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents? Lancet Oncol 4 2003 605-615
-
(2003)
Lancet Oncol
, vol.4
, pp. 605-615
-
-
Gasparini, G.1
Longo, R.2
Sarmiento, R.3
-
50
-
-
0034939632
-
Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: An adaptive metabolic system
-
J.K. Reddy T. Hashimoto Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: An adaptive metabolic system Annu Rev Nutr 21 2001 193-230
-
(2001)
Annu Rev Nutr
, vol.21
, pp. 193-230
-
-
Reddy, J.K.1
Hashimoto, T.2
-
51
-
-
0034569799
-
Peroxisome proliferator-activated receptors, coactivators, and downstream targets
-
Spring
-
C. Qi Y. Zhu J.K. Reddy Peroxisome proliferator-activated receptors, coactivators, and downstream targets Cell Biochem Biophys 32 Spring 2000 187-204
-
(2000)
Cell Biochem Biophys
, vol.32
, pp. 187-204
-
-
Qi, C.1
Zhu, Y.2
Reddy, J.K.3
-
52
-
-
0033542873
-
Medical significance of peroxisome proliferator-activated receptors
-
J. Vamecq N. Latruffe Medical significance of peroxisome proliferator-activated receptors Lancet 354 1999 141-148
-
(1999)
Lancet
, vol.354
, pp. 141-148
-
-
Vamecq, J.1
Latruffe, N.2
-
53
-
-
0032816777
-
Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
-
J.C. Fruchart P. Duriez B. Staels Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis Curr Opin Lipidol 10 1999 245-257
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 245-257
-
-
Fruchart, J.C.1
Duriez, P.2
Staels, B.3
-
54
-
-
0000548749
-
Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging
-
I. Pineda Torra P. Gervois B. Staels Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging Curr Opin Lipidol 10 1999 151-159
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 151-159
-
-
Pineda Torra, I.1
Gervois, P.2
Staels, B.3
-
55
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
B. Desvergne W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr Rev 20 1999 649-688
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
56
-
-
0033305499
-
Orphan nuclear receptors: From gene to function
-
V. Giguere Orphan nuclear receptors: From gene to function Endocr Rev 20 1999 689-725
-
(1999)
Endocr Rev
, vol.20
, pp. 689-725
-
-
Giguere, V.1
-
57
-
-
0030669636
-
The role of peroxisome proliferator activated receptor alpha in peroxisome proliferation, physiological homeostasis, and chemical carcinogenesis
-
F.J. Gonzalez The role of peroxisome proliferator activated receptor alpha in peroxisome proliferation, physiological homeostasis, and chemical carcinogenesis Adv Exp Med Biol 422 1997 109-125
-
(1997)
Adv Exp Med Biol
, vol.422
, pp. 109-125
-
-
Gonzalez, F.J.1
-
58
-
-
0028972025
-
15-Deoxy-delta 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
B.M. Forman P. Tontonoz J. Chen et al. 15-Deoxy-delta 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma Cell 83 1995 803-812
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
-
59
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
S.A. Kliewer J.M. Lenhard T.M. Willson et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation Cell 83 1995 813-819
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
-
60
-
-
0029661982
-
The PPARalpha-leukotriene B4 pathway to inflammation control
-
[see comments]
-
P.R. Devchand H. Keller J.M. Peters et al. The PPARalpha-leukotriene B4 pathway to inflammation control [see comments] Nature 384 1996 39-43
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
-
61
-
-
0036083383
-
85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells
-
C. Han A.J. Demetris G. Michalopoulos et al. 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells Am J Physiol Gastrointest Liver Physiol 282 2002 G586-G597
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
-
-
Han, C.1
Demetris, A.J.2
Michalopoulos, G.3
-
62
-
-
0037031820
-
85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells
-
R. Pawliczak C. Han X.L. Huang et al. 85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells J Biol Chem 277 2002 33153-33163
-
(2002)
J Biol Chem
, vol.277
, pp. 33153-33163
-
-
Pawliczak, R.1
Han, C.2
Huang, X.L.3
-
63
-
-
10344233226
-
Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells
-
R. Pawliczak C. Logun P. Madara et al. Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells J Biol Chem 279 2004 48550-48561
-
(2004)
J Biol Chem
, vol.279
, pp. 48550-48561
-
-
Pawliczak, R.1
Logun, C.2
Madara, P.3
-
64
-
-
17144403485
-
Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma
-
T.C. Tang R.T. Poon C.P. Lau et al. Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma World J Gastroenterol 11 2005 1896-1902
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1896-1902
-
-
Tang, T.C.1
Poon, R.T.2
Lau, C.P.3
-
65
-
-
0030049390
-
Prostaglandin synthase 2
-
H.R. Herschman Prostaglandin synthase 2 Biochim Biophys Acta 1299 1996 125-140
-
(1996)
Biochim Biophys Acta
, vol.1299
, pp. 125-140
-
-
Herschman, H.R.1
-
66
-
-
0033855617
-
Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/ enhancer-binding proteins
-
N.A. Callejas L. Bosca C.S. Williams et al. Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins Gastroenterology 119 2000 493-501
-
(2000)
Gastroenterology
, vol.119
, pp. 493-501
-
-
Callejas, N.A.1
Bosca, L.2
Williams, C.S.3
-
67
-
-
0036955336
-
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
-
E. Lara-Pezzi M.V. Gomez-Gaviro B.G. Galvez et al. The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression J Clin Invest 110 2002 1831-1838
-
(2002)
J Clin Invest
, vol.110
, pp. 1831-1838
-
-
Lara-Pezzi, E.1
Gomez-Gaviro, M.V.2
Galvez, B.G.3
-
68
-
-
4744351642
-
Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2
-
A.S. Cheng H.L. Chan W.K. Leung et al. Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2 Mod Pathol 17 2004 1169-1179
-
(2004)
Mod Pathol
, vol.17
, pp. 1169-1179
-
-
Cheng, A.S.1
Chan, H.L.2
Leung, W.K.3
-
69
-
-
22544447811
-
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: Role of prostaglandin E2 in RNA replication
-
G. Waris A. Siddiqui Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: Role of prostaglandin E2 in RNA replication J Virol 79 2005 9725-9734
-
(2005)
J Virol
, vol.79
, pp. 9725-9734
-
-
Waris, G.1
Siddiqui, A.2
-
70
-
-
19944411839
-
Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta
-
M. Joo Y.S. Hahn M. Kwon et al. Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta J Virol 79 2005 7648-7657
-
(2005)
J Virol
, vol.79
, pp. 7648-7657
-
-
Joo, M.1
Hahn, Y.S.2
Kwon, M.3
-
71
-
-
17644368895
-
Effect of heptitis C virus core protein on cellular gene expression: Specific inhibition of cyclooxygenase 2
-
R. Jhaveri P. Kundu A.M. Shapiro et al. Effect of heptitis C virus core protein on cellular gene expression: Specific inhibition of cyclooxygenase 2 J Infect Dis 191 2005 1498-1506
-
(2005)
J Infect Dis
, vol.191
, pp. 1498-1506
-
-
Jhaveri, R.1
Kundu, P.2
Shapiro, A.M.3
-
72
-
-
0037310126
-
Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways
-
Y. Araki S. Okamura S.P. Hussain et al. Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways Cancer Res 63 2003 728-734
-
(2003)
Cancer Res
, vol.63
, pp. 728-734
-
-
Araki, Y.1
Okamura, S.2
Hussain, S.P.3
-
73
-
-
3543100257
-
Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells
-
H. Murata S. Tsuji M. Tsujii et al. Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells Lab Invest 84 2004 1050-1059
-
(2004)
Lab Invest
, vol.84
, pp. 1050-1059
-
-
Murata, H.1
Tsuji, S.2
Tsujii, M.3
-
74
-
-
0034676333
-
IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells
-
A. Di Popolo A. Memoli A. Apicella et al. IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells Oncogene 19 2000 5517-5524
-
(2000)
Oncogene
, vol.19
, pp. 5517-5524
-
-
Di Popolo, A.1
Memoli, A.2
Apicella, A.3
-
75
-
-
0031022784
-
Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization
-
A. Marchio M. Meddeb P. Pineau et al. Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization Genes Chromosomes Cancer 18 1997 59-65
-
(1997)
Genes Chromosomes Cancer
, vol.18
, pp. 59-65
-
-
Marchio, A.1
Meddeb, M.2
Pineau, P.3
-
76
-
-
0035446479
-
Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis
-
F. Niketeghad H.J. Decker W.H. Caselmann et al. Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis Br J Cancer 85 2001 697-704
-
(2001)
Br J Cancer
, vol.85
, pp. 697-704
-
-
Niketeghad, F.1
Decker, H.J.2
Caselmann, W.H.3
-
77
-
-
0033613852
-
Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways
-
M. Murakami T. Kambe S. Shimbara et al. Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways J Biol Chem 274 1999 3103-3115
-
(1999)
J Biol Chem
, vol.274
, pp. 3103-3115
-
-
Murakami, M.1
Kambe, T.2
Shimbara, S.3
-
78
-
-
18544383004
-
Cyclooxygenase-2 mRNA is up-regulated in cirrhotic or chronic hepatitis liver adjacent to hepatocellular carcinoma
-
S. Morinaga Y. Yamamoto Y. Noguchi et al. Cyclooxygenase-2 mRNA is up-regulated in cirrhotic or chronic hepatitis liver adjacent to hepatocellular carcinoma J Gastroenterol Hepatol 17 2002 1110-1116
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 1110-1116
-
-
Morinaga, S.1
Yamamoto, Y.2
Noguchi, Y.3
-
79
-
-
0037411105
-
Expression of cyclooxygenase2 and cytosolic phospholipase A(2) in the liver tissue of patients with chronic hepatitis and liver cirrhosis
-
J. Cheng H. Imanishi H. Iijima et al. Expression of cyclooxygenase2 and cytosolic phospholipase A(2) in the liver tissue of patients with chronic hepatitis and liver cirrhosis Hepatol Res 23 2002 185-195
-
(2002)
Hepatol Res
, vol.23
, pp. 185-195
-
-
Cheng, J.1
Imanishi, H.2
Iijima, H.3
-
80
-
-
1842454831
-
Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: A possible role for COX-2 in the pathogenesis of liver cirrhosis
-
N.A. Mohammed S.A. Abd El-Aleem H.A. El-Hafiz et al. Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: A possible role for COX-2 in the pathogenesis of liver cirrhosis J Clin Pathol 57 2004 350-354
-
(2004)
J Clin Pathol
, vol.57
, pp. 350-354
-
-
Mohammed, N.A.1
Abd El-Aleem, S.A.2
El-Hafiz, H.A.3
-
82
-
-
0027416652
-
Hyperdynamic state in chronic liver diseases
-
R.J. Groszmann Hyperdynamic state in chronic liver diseases J Hepatol 17 Suppl. 2 1993 S38-S40
-
(1993)
J Hepatol
, vol.17
, Issue.SUPPL. 2
-
-
Groszmann, R.J.1
-
83
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
M. Tsujii S. Kawano S. Tsuji et al. Cyclooxygenase regulates angiogenesis induced by colon cancer cells Cell 93 1998 705-716
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
-
84
-
-
0042666923
-
JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1
-
H. Yamamoto M. Kondo S. Nakamori et al. JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1 Gastroenterology 125 2003 556-571
-
(2003)
Gastroenterology
, vol.125
, pp. 556-571
-
-
Yamamoto, H.1
Kondo, M.2
Nakamori, S.3
-
85
-
-
0031778206
-
Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
-
O.N. El-Assal A. Yamanoi Y. Soda et al. Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver Hepatology 27 1998 1554-1562
-
(1998)
Hepatology
, vol.27
, pp. 1554-1562
-
-
El-Assal, O.N.1
Yamanoi, A.2
Soda, Y.3
-
86
-
-
0027386134
-
Interferon-alpha increases prostaglandin E2 production by cultured liver biopsy in patients with chronic viral hepatitis: Can non-steroidal anti-inflammatory drugs improve the therapeutic response to interferon?
-
P. Andreone C. Cursaro G. Gasbarrini et al. Interferon-alpha increases prostaglandin E2 production by cultured liver biopsy in patients with chronic viral hepatitis: Can non-steroidal anti-inflammatory drugs improve the therapeutic response to interferon? J Hepatol 19 1993 228-231
-
(1993)
J Hepatol
, vol.19
, pp. 228-231
-
-
Andreone, P.1
Cursaro, C.2
Gasbarrini, G.3
-
87
-
-
0032811406
-
Nonsteroidal anti-inflammatory drug metabolism potentiates interferon alfa signaling by increasing STAT1 phosphorylation
-
S. Giambartolomei M. Artini C. Almerighi et al. Nonsteroidal anti-inflammatory drug metabolism potentiates interferon alfa signaling by increasing STAT1 phosphorylation Hepatology 30 1999 510-516
-
(1999)
Hepatology
, vol.30
, pp. 510-516
-
-
Giambartolomei, S.1
Artini, M.2
Almerighi, C.3
-
88
-
-
0038383547
-
Interferon-alpha combined with ketoprofen as treatment of naive patients with chronic hepatitis C: A randomized controlled trial
-
P. Andreone A. Gramenzi C. Cursaro et al. Interferon-alpha combined with ketoprofen as treatment of naive patients with chronic hepatitis C: A randomized controlled trial J Viral Hepat 10 2003 306-309
-
(2003)
J Viral Hepat
, vol.10
, pp. 306-309
-
-
Andreone, P.1
Gramenzi, A.2
Cursaro, C.3
-
89
-
-
1942489017
-
Anti-HCV activities of selective polyunsaturated fatty acids
-
G.Z. Leu T.Y. Lin J.T. Hsu Anti-HCV activities of selective polyunsaturated fatty acids Biochem Biophys Res Commun 318 2004 275-280
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 275-280
-
-
Leu, G.Z.1
Lin, T.Y.2
Hsu, J.T.3
-
90
-
-
0041570010
-
Arachidonic acid in mononuclear cells and its clinical significance in HCV cirrhotic patients
-
M. Okita K. Tomioka Y. Ota et al. Arachidonic acid in mononuclear cells and its clinical significance in HCV cirrhotic patients Nutrition 19 2003 727-732
-
(2003)
Nutrition
, vol.19
, pp. 727-732
-
-
Okita, M.1
Tomioka, K.2
Ota, Y.3
-
91
-
-
1442290121
-
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha
-
E.J. Moon C.H. Jeong J.W. Jeong et al. Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha FASEB J 18 2004 382-384
-
(2004)
FASEB J
, vol.18
, pp. 382-384
-
-
Moon, E.J.1
Jeong, C.H.2
Jeong, J.W.3
-
92
-
-
0036169713
-
Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy
-
A.S. Cheng H.L. Chan N.W. Leung et al. Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy Aliment Pharmacol Ther 16 2002 251-260
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 251-260
-
-
Cheng, A.S.1
Chan, H.L.2
Leung, N.W.3
-
93
-
-
0031059248
-
Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat
-
[see comments]
-
A.A. Nanji L. Miao P. Thomas et al. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat [see comments] Gastroenterology 112 1997 943-951
-
(1997)
Gastroenterology
, vol.112
, pp. 943-951
-
-
Nanji, A.A.1
Miao, L.2
Thomas, P.3
-
94
-
-
0030665615
-
Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat
-
A.A. Nanji D. Zakim A. Rahemtulla et al. Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat Hepatology 26 1997 1538-1545
-
(1997)
Hepatology
, vol.26
, pp. 1538-1545
-
-
Nanji, A.A.1
Zakim, D.2
Rahemtulla, A.3
-
95
-
-
0034090264
-
Hepatocellular carcinoma
-
K. Okuda Hepatocellular carcinoma J Hepatol 32 2000 225-237
-
(2000)
J Hepatol
, vol.32
, pp. 225-237
-
-
Okuda, K.1
-
96
-
-
0036859903
-
Understanding the hypercarcinogenic state in chronic hepatitis: A clue to the prevention of human hepatocellular carcinoma
-
O. Hino K. Kajino T. Umeda Understanding the hypercarcinogenic state in chronic hepatitis: A clue to the prevention of human hepatocellular carcinoma J Gastroenterol 37 2002 883-887
-
(2002)
J Gastroenterol
, vol.37
, pp. 883-887
-
-
Hino, O.1
Kajino, K.2
Umeda, T.3
-
97
-
-
0028226265
-
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
-
T. Kosaka A. Miyata H. Ihara et al. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2 Eur J Biochem 221 1994 889-897
-
(1994)
Eur J Biochem
, vol.221
, pp. 889-897
-
-
Kosaka, T.1
Miyata, A.2
Ihara, H.3
-
98
-
-
0027223097
-
Characterization and hormonal regulation of the promoter of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Identification of functional and protein-binding regions
-
J. Sirois L.O. Levy D.L. Simmons et al. Characterization and hormonal regulation of the promoter of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Identification of functional and protein-binding regions J Biol Chem 268 1993 12199-12206
-
(1993)
J Biol Chem
, vol.268
, pp. 12199-12206
-
-
Sirois, J.1
Levy, L.O.2
Simmons, D.L.3
-
99
-
-
0026702494
-
Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
-
B.S. Fletcher D.A. Kujubu D.M. Perrin et al. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase J Biol Chem 267 1992 4338-4344
-
(1992)
J Biol Chem
, vol.267
, pp. 4338-4344
-
-
Fletcher, B.S.1
Kujubu, D.A.2
Perrin, D.M.3
-
100
-
-
0035086794
-
Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells
-
J.W. Lim H. Kim K.H. Kim Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells Lab Invest 81 2001 349-360
-
(2001)
Lab Invest
, vol.81
, pp. 349-360
-
-
Lim, J.W.1
Kim, H.2
Kim, K.H.3
-
101
-
-
7244234090
-
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: Role of viral core and NS5A proteins
-
O. Nunez A. Fernandez-Martinez P.L. Majano et al. Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: Role of viral core and NS5A proteins Gut 53 2004 1665-1672
-
(2004)
Gut
, vol.53
, pp. 1665-1672
-
-
Nunez, O.1
Fernandez-Martinez, A.2
Majano, P.L.3
-
102
-
-
4544283162
-
Effect of prostaglandin E2 and prostaglandin I2 on PDGF-induced proliferation of LI90, a human hepatic stellate cell line
-
A.Y. Hui A.S. Cheng H.L. Chan et al. Effect of prostaglandin E2 and prostaglandin I2 on PDGF-induced proliferation of LI90, a human hepatic stellate cell line Prostaglandins Leukot Essent Fatty Acids 71 2004 329-333
-
(2004)
Prostaglandins Leukot Essent Fatty Acids
, vol.71
, pp. 329-333
-
-
Hui, A.Y.1
Cheng, A.S.2
Chan, H.L.3
-
103
-
-
0036402137
-
Inhibition of the expression of alpha-smooth muscle actin in human hepatic stellate cell line, LI90, by a selective cyclooxygenase 2 inhibitor, NS-398
-
J. Cheng H. Imanishi W. Liu et al. Inhibition of the expression of alpha-smooth muscle actin in human hepatic stellate cell line, LI90, by a selective cyclooxygenase 2 inhibitor, NS-398 Biochem Biophys Res Commun 297 2002 1128-1134
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 1128-1134
-
-
Cheng, J.1
Imanishi, H.2
Liu, W.3
-
104
-
-
4444359223
-
Prostaglandin E2 inhibits transforming growth factor beta 1-mediated induction of collagen alpha 1(I) in hepatic stellate cells
-
A.Y. Hui A.J. Dannenberg J.J. Sung et al. Prostaglandin E2 inhibits transforming growth factor beta 1-mediated induction of collagen alpha 1(I) in hepatic stellate cells J Hepatol 41 2004 251-258
-
(2004)
J Hepatol
, vol.41
, pp. 251-258
-
-
Hui, A.Y.1
Dannenberg, A.J.2
Sung, J.J.3
-
105
-
-
17744398428
-
Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells
-
E. Efsen A. Bonacchi S. Pastacaldi et al. Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells Hepatology 33 2001 713-721
-
(2001)
Hepatology
, vol.33
, pp. 713-721
-
-
Efsen, E.1
Bonacchi, A.2
Pastacaldi, S.3
-
106
-
-
21744459082
-
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation
-
A. Planaguma J. Claria R. Miquel et al. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation FASEB J 19 2005 1120-1122
-
(2005)
FASEB J
, vol.19
, pp. 1120-1122
-
-
Planaguma, A.1
Claria, J.2
Miquel, R.3
-
107
-
-
0035461364
-
Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy
-
M. Casado N.A. Callejas J. Rodrigo et al. Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy FASEB J 15 2001 2016-2018
-
(2001)
FASEB J
, vol.15
, pp. 2016-2018
-
-
Casado, M.1
Callejas, N.A.2
Rodrigo, J.3
-
108
-
-
0035663287
-
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice
-
T.P. Reilly J.N. Brady M.R. Marchick et al. A protective role for cyclooxygenase-2 in drug-induced liver injury in mice Chem Res Toxicol 14 2001 1620-1628
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 1620-1628
-
-
Reilly, T.P.1
Brady, J.N.2
Marchick, M.R.3
-
109
-
-
18344372909
-
Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells
-
S. Abiru K. Nakao T. Ichikawa et al. Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells Hepatology 35 2002 1117-1124
-
(2002)
Hepatology
, vol.35
, pp. 1117-1124
-
-
Abiru, S.1
Nakao, K.2
Ichikawa, T.3
-
110
-
-
17844404832
-
Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells
-
R. Mayoral A. Fernandez-Martinez L. Bosca et al. Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells Carcinogenesis 26 2005 753-761
-
(2005)
Carcinogenesis
, vol.26
, pp. 753-761
-
-
Mayoral, R.1
Fernandez-Martinez, A.2
Bosca, L.3
-
111
-
-
0035082529
-
Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes
-
N.A. Callejas M. Casado M.J. Diaz-Guerra et al. Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes Hepatology 33 2001 860-867
-
(2001)
Hepatology
, vol.33
, pp. 860-867
-
-
Callejas, N.A.1
Casado, M.2
Diaz-Guerra, M.J.3
-
112
-
-
0035207130
-
Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer
-
F. Cianchi C. Cortesini P. Bechi et al. Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer Gastroenterology 121 2001 1339-1347
-
(2001)
Gastroenterology
, vol.121
, pp. 1339-1347
-
-
Cianchi, F.1
Cortesini, C.2
Bechi, P.3
-
113
-
-
0035190559
-
Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma
-
I.O. Ng R.T. Poon J.M. Lee et al. Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma Am J Clin Pathol 116 2001 838-845
-
(2001)
Am J Clin Pathol
, vol.116
, pp. 838-845
-
-
Ng, I.O.1
Poon, R.T.2
Lee, J.M.3
-
114
-
-
0035132143
-
Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: A prospective study
-
R.T. Poon I.O. Ng C. Lau et al. Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: A prospective study Ann Surg 233 2001 227-235
-
(2001)
Ann Surg
, vol.233
, pp. 227-235
-
-
Poon, R.T.1
Ng, I.O.2
Lau, C.3
-
115
-
-
0035811070
-
Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells
-
S. Murono H. Inoue T. Tanabe et al. Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells Proc Natl Acad Sci USA 98 2001 6905-6910
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6905-6910
-
-
Murono, S.1
Inoue, H.2
Tanabe, T.3
-
116
-
-
0034796261
-
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
-
M. Sonoshita K. Takaku N. Sasaki et al. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice Nat Med 7 2001 1048-1051
-
(2001)
Nat Med
, vol.7
, pp. 1048-1051
-
-
Sonoshita, M.1
Takaku, K.2
Sasaki, N.3
-
117
-
-
19144366561
-
Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor
-
M. Mise S. Arii H. Higashituji et al. Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor Hepatology 23 1996 455-464
-
(1996)
Hepatology
, vol.23
, pp. 455-464
-
-
Mise, M.1
Arii, S.2
Higashituji, H.3
-
118
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
I. Vivanco C.L. Sawyers The phosphatidylinositol 3-Kinase AKT pathway in human cancer Nat Rev Cancer 2 2002 489-501
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
119
-
-
0035949699
-
AKT plays a central role in tumorigenesis
-
J.R. Testa A. Bellacosa AKT plays a central role in tumorigenesis Proc Natl Acad Sci USA 98 2001 10983-10985
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10983-10985
-
-
Testa, J.R.1
Bellacosa, A.2
-
120
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
M.A. Lawlor D.R. Alessi PKB/Akt: A key mediator of cell proliferation, survival and insulin responses? J Cell Sci 114 2001 2903-2910
-
(2001)
J Cell Sci
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
121
-
-
0346850745
-
Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis
-
C.M. Schmidt Y. Wang C. Wiesenauer Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis J Gastrointest Surg 7 2003 1024-1033
-
(2003)
J Gastrointest Surg
, vol.7
, pp. 1024-1033
-
-
Schmidt, C.M.1
Wang, Y.2
Wiesenauer, C.3
-
122
-
-
0034646688
-
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
-
A.L. Hsu T.T. Ching D.S. Wang et al. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2 J Biol Chem 275 2000 11397-11403
-
(2000)
J Biol Chem
, vol.275
, pp. 11397-11403
-
-
Hsu, A.L.1
Ching, T.T.2
Wang, D.S.3
-
123
-
-
0035650943
-
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib
-
S. Grosch I. Tegeder E. Niederberger et al. COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib FASEB J 15 2001 2742-2744
-
(2001)
FASEB J
, vol.15
, pp. 2742-2744
-
-
Grosch, S.1
Tegeder, I.2
Niederberger, E.3
-
124
-
-
0037008686
-
Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line
-
S. Arico S. Pattingre C. Bauvy et al. Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line J Biol Chem 277 2002 27613-27621
-
(2002)
J Biol Chem
, vol.277
, pp. 27613-27621
-
-
Arico, S.1
Pattingre, S.2
Bauvy, C.3
-
125
-
-
0036531924
-
Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines
-
C. Waskewich R.D. Blumenthal H. Li et al. Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines Cancer Res 62 2002 2029-2033
-
(2002)
Cancer Res
, vol.62
, pp. 2029-2033
-
-
Waskewich, C.1
Blumenthal, R.D.2
Li, H.3
-
126
-
-
0035851187
-
Ppargamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
E.D. Rosen B.M. Spiegelman Ppargamma: A nuclear regulator of metabolism, differentiation, and cell growth J Biol Chem 276 2001 37731-37734
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
127
-
-
0031589638
-
Peroxisome proliferator-activated receptor gamma: A key regulator of adipogenesis and systemic insulin sensitivity
-
B.M. Spiegelman Peroxisome proliferator-activated receptor gamma: A key regulator of adipogenesis and systemic insulin sensitivity Eur J Med Res 2 1997 457-464
-
(1997)
Eur J Med Res
, vol.2
, pp. 457-464
-
-
Spiegelman, B.M.1
-
128
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
O. Gavrilova M. Haluzik K. Matsusue et al. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass J Biol Chem 278 2003 34268-34276
-
(2003)
J Biol Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
-
129
-
-
0038121972
-
PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway
-
C. Han A.J. Demetris G.K. Michalopoulos et al. PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway Hepatology 38 2003 167-177
-
(2003)
Hepatology
, vol.38
, pp. 167-177
-
-
Han, C.1
Demetris, A.J.2
Michalopoulos, G.K.3
-
130
-
-
0347753697
-
Peroxisome-proliferator-activated receptors and cancers: Complex stories
-
L. Michalik B. Desvergne W. Wahli Peroxisome-proliferator-activated receptors and cancers: Complex stories Nat Rev Cancer 4 2004 61-70
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 61-70
-
-
Michalik, L.1
Desvergne, B.2
Wahli, W.3
-
131
-
-
0035035402
-
Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines
-
H. Koga S. Sakisaka M. Harada et al. Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines Hepatology 33 2001 1087-1097
-
(2001)
Hepatology
, vol.33
, pp. 1087-1097
-
-
Koga, H.1
Sakisaka, S.2
Harada, M.3
-
132
-
-
0345687980
-
Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells
-
W. Motomura N. Takahashi M. Nagamine et al. Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells Int J Cancer 108 2004 41-46
-
(2004)
Int J Cancer
, vol.108
, pp. 41-46
-
-
Motomura, W.1
Takahashi, N.2
Nagamine, M.3
-
133
-
-
20144389197
-
Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells
-
K.L. Schaefer K. Wada H. Takahashi et al. Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells Cancer Res 65 2005 2251-2259
-
(2005)
Cancer Res
, vol.65
, pp. 2251-2259
-
-
Schaefer, K.L.1
Wada, K.2
Takahashi, H.3
-
134
-
-
17844395188
-
Peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition of human hepatocellular carcinoma
-
M.A. Rumi H. Sato S. Ishihara et al. Peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition of human hepatocellular carcinoma Br J Cancer 84 2001 1640-1647
-
(2001)
Br J Cancer
, vol.84
, pp. 1640-1647
-
-
Rumi, M.A.1
Sato, H.2
Ishihara, S.3
-
135
-
-
0038713185
-
Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells
-
H. Koga M. Harada M. Ohtsubo et al. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells Hepatology 37 2003 1086-1096
-
(2003)
Hepatology
, vol.37
, pp. 1086-1096
-
-
Koga, H.1
Harada, M.2
Ohtsubo, M.3
-
136
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor
-
P. Tontonoz S. Singer B.M. Forman et al. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor Proc Natl Acad Sci USA 94 1997 237-241
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
-
137
-
-
0033616795
-
Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma
-
G.D. Demetri C.D. Fletcher E. Mueller et al. Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma Proc Natl Acad Sci USA 96 1999 3951-3956
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3951-3956
-
-
Demetri, G.D.1
Fletcher, C.D.2
Mueller, E.3
-
138
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARgamma
-
P. Sarraf E. Mueller D. Jones et al. Differentiation and reversal of malignant changes in colon cancer through PPARgamma Nat Med 4 1998 1046-1052
-
(1998)
Nat Med
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
-
139
-
-
0033152206
-
Loss-of-function mutations in PPAR gamma associated with human colon cancer
-
P. Sarraf E. Mueller W.M. Smith et al. Loss-of-function mutations in PPAR gamma associated with human colon cancer Mol Cell 3 1999 799-804
-
(1999)
Mol Cell
, vol.3
, pp. 799-804
-
-
Sarraf, P.1
Mueller, E.2
Smith, W.M.3
-
140
-
-
0031844535
-
The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers
-
R.N. DuBois R. Gupta J. Brockman et al. The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers Carcinogenesis 19 1998 49-53
-
(1998)
Carcinogenesis
, vol.19
, pp. 49-53
-
-
DuBois, R.N.1
Gupta, R.2
Brockman, J.3
-
141
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
E. Elstner C. Muller K. Koshizuka et al. Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice Proc Natl Acad Sci USA 95 1998 8806-8811
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
-
142
-
-
0343855442
-
Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer
-
E. Mueller M. Smith P. Sarraf et al. Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer Proc Natl Acad Sci USA 97 2000 10990-10995
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10990-10995
-
-
Mueller, E.1
Smith, M.2
Sarraf, P.3
-
143
-
-
0032145363
-
Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
-
T. Kubota K. Koshizuka E.A. Williamson et al. Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo Cancer Res 58 1998 3344-3352
-
(1998)
Cancer Res
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
Koshizuka, K.2
Williamson, E.A.3
-
144
-
-
0034880165
-
Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells
-
K.I. Nakashiro Y. Hayashi A. Kita et al. Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells Am J Pathol 159 2001 591-597
-
(2001)
Am J Pathol
, vol.159
, pp. 591-597
-
-
Nakashiro, K.I.1
Hayashi, Y.2
Kita, A.3
-
145
-
-
0034652462
-
Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer
-
T.H. Chang E. Szabo Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer Cancer Res 60 2000 1129-1138
-
(2000)
Cancer Res
, vol.60
, pp. 1129-1138
-
-
Chang, T.H.1
Szabo, E.2
-
146
-
-
0035394518
-
Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies
-
T. Ikezoe C.W. Miller S. Kawano et al. Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies Cancer Res 61 2001 5307-5310
-
(2001)
Cancer Res
, vol.61
, pp. 5307-5310
-
-
Ikezoe, T.1
Miller, C.W.2
Kawano, S.3
-
147
-
-
0034889267
-
Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells
-
C.E. Clay A.M. Namen G. Atsumi et al. Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells J Invest Med 49 2001 413-420
-
(2001)
J Invest Med
, vol.49
, pp. 413-420
-
-
Clay, C.E.1
Namen, A.M.2
Atsumi, G.3
-
148
-
-
12144287188
-
PPAR gamma signaling exacerbates mammary gland tumor development
-
E. Saez J. Rosenfeld A. Livolsi et al. PPAR gamma signaling exacerbates mammary gland tumor development Genes Dev 18 2004 528-540
-
(2004)
Genes Dev
, vol.18
, pp. 528-540
-
-
Saez, E.1
Rosenfeld, J.2
Livolsi, A.3
-
149
-
-
0031694577
-
Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
-
A.M. Lefebvre I. Chen P. Desreumaux et al. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice Nat Med 4 1998 1053-1057
-
(1998)
Nat Med
, vol.4
, pp. 1053-1057
-
-
Lefebvre, A.M.1
Chen, I.2
Desreumaux, P.3
-
150
-
-
0031667938
-
Activators of the nuclear receptor PPARgamma enhance colon polyp formation
-
E. Saez P. Tontonoz M.C. Nelson et al. Activators of the nuclear receptor PPARgamma enhance colon polyp formation Nat Med 4 1998 1058-1061
-
(1998)
Nat Med
, vol.4
, pp. 1058-1061
-
-
Saez, E.1
Tontonoz, P.2
Nelson, M.C.3
-
151
-
-
0037109043
-
APC-dependent suppression of colon carcinogenesis by PPARgamma
-
G.D. Girnun W.M. Smith S. Drori et al. APC-dependent suppression of colon carcinogenesis by PPARgamma Proc Natl Acad Sci USA 99 2002 13771-13776
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13771-13776
-
-
Girnun, G.D.1
Smith, W.M.2
Drori, S.3
-
152
-
-
7244253108
-
Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-beta-induced mitoinhibition
-
C. Han A.J. Demetris Y. Liu et al. Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-beta-induced mitoinhibition J Biol Chem 279 2004 44344-44354
-
(2004)
J Biol Chem
, vol.279
, pp. 44344-44354
-
-
Han, C.1
Demetris, A.J.2
Liu, Y.3
-
153
-
-
0142186679
-
Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma
-
L.C. Bell-Parikh T. Ide J.A. Lawson et al. Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma J Clin Invest 112 2003 945-955
-
(2003)
J Clin Invest
, vol.112
, pp. 945-955
-
-
Bell-Parikh, L.C.1
Ide, T.2
Lawson, J.A.3
-
154
-
-
85047690989
-
15-Deoxy-delta 12,14-PGJ2: Endogenous PPARgamma ligand or minor eicosanoid degradation product
-
W.S. Powell 15-Deoxy-delta 12,14-PGJ2: Endogenous PPARgamma ligand or minor eicosanoid degradation product J Clin Invest 112 2003 828-830
-
(2003)
J Clin Invest
, vol.112
, pp. 828-830
-
-
Powell, W.S.1
-
155
-
-
0018888058
-
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
-
J.K. Reddy D.L. Azarnoff C.E. Hignite Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens Nature 283 1980 397-398
-
(1980)
Nature
, vol.283
, pp. 397-398
-
-
Reddy, J.K.1
Azarnoff, D.L.2
Hignite, C.E.3
-
156
-
-
0033849091
-
Peroxisome proliferator-activated receptors in tumorigenesis: Targets of tumour promotion and treatment
-
S.J. Roberts-Thomson Peroxisome proliferator-activated receptors in tumorigenesis: Targets of tumour promotion and treatment Immunol Cell Biol 78 2000 436-441
-
(2000)
Immunol Cell Biol
, vol.78
, pp. 436-441
-
-
Roberts-Thomson, S.J.1
-
157
-
-
0034677853
-
Central role of PPARalpha in the mechanism of action of hepatocarcinogenic peroxisome proliferators
-
J.C. Corton P.J. Lapinskas F.J. Gonzalez Central role of PPARalpha in the mechanism of action of hepatocarcinogenic peroxisome proliferators Mutat Res 448 2000 139-151
-
(2000)
Mutat Res
, vol.448
, pp. 139-151
-
-
Corton, J.C.1
Lapinskas, P.J.2
Gonzalez, F.J.3
-
158
-
-
0032545018
-
Mechanism of action of the nongenotoxic peroxisome proliferators: Role of the peroxisome proliferator-activator receptor alpha
-
F.J. Gonzalez J.M. Peters R.C. Cattley Mechanism of action of the nongenotoxic peroxisome proliferators: Role of the peroxisome proliferator-activator receptor alpha J Natl Cancer Inst 90 1998 1702-1709
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1702-1709
-
-
Gonzalez, F.J.1
Peters, J.M.2
Cattley, R.C.3
-
159
-
-
0029557218
-
Peroxisome proliferation: Current mechanisms relating to nongenotoxic carcinogenesis
-
B.G. Lake Peroxisome proliferation: Current mechanisms relating to nongenotoxic carcinogenesis Toxicol Lett 82-83 1995 673-681
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 673-681
-
-
Lake, B.G.1
-
160
-
-
0031418657
-
Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
-
J.M. Peters R.C. Cattley F.J. Gonzalez Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643 Carcinogenesis 18 1997 2029-2033
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
161
-
-
0038648463
-
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: Comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen
-
K. Meyer J.S. Lee P.A. Dyck et al. Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen Carcinogenesis 24 2003 975-984
-
(2003)
Carcinogenesis
, vol.24
, pp. 975-984
-
-
Meyer, K.1
Lee, J.S.2
Dyck, P.A.3
-
162
-
-
0024430314
-
Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis
-
J.K. Reddy M.S. Rao Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis Mutat Res 214 1989 63-68
-
(1989)
Mutat Res
, vol.214
, pp. 63-68
-
-
Reddy, J.K.1
Rao, M.S.2
-
163
-
-
0034678013
-
Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis
-
A.V. Yeldandi M.S. Rao J.K. Reddy Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis Mutat Res 448 2000 159-177
-
(2000)
Mutat Res
, vol.448
, pp. 159-177
-
-
Yeldandi, A.V.1
Rao, M.S.2
Reddy, J.K.3
-
164
-
-
0021368812
-
Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator
-
M.S. Rao N.D. Lalwani T.K. Watanabe et al. Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator Cancer Res 44 1984 1072-1076
-
(1984)
Cancer Res
, vol.44
, pp. 1072-1076
-
-
Rao, M.S.1
Lalwani, N.D.2
Watanabe, T.K.3
-
165
-
-
0031781381
-
Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver
-
J.M. Peters T. Aoyama R.C. Cattley et al. Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver Carcinogenesis 19 1998 1989-1994
-
(1998)
Carcinogenesis
, vol.19
, pp. 1989-1994
-
-
Peters, J.M.1
Aoyama, T.2
Cattley, R.C.3
-
166
-
-
0030013157
-
Growth regulation by peroxisome proliferators: Opposing activities in early and late G1
-
B.J. Ledwith T.E. Johnson L.K. Wagner et al. Growth regulation by peroxisome proliferators: Opposing activities in early and late G1 Cancer Res 56 1996 3257-3264
-
(1996)
Cancer Res
, vol.56
, pp. 3257-3264
-
-
Ledwith, B.J.1
Johnson, T.E.2
Wagner, L.K.3
-
167
-
-
0031427598
-
Decreased hepatocyte growth factor level by Wy-14,643, non-genotoxic hepatocarcinogen in F-344 rats
-
Y. Motoki H. Tamura R. Morita et al. Decreased hepatocyte growth factor level by Wy-14,643, non-genotoxic hepatocarcinogen in F-344 rats Carcinogenesis 18 1997 1303-1309
-
(1997)
Carcinogenesis
, vol.18
, pp. 1303-1309
-
-
Motoki, Y.1
Tamura, H.2
Morita, R.3
-
168
-
-
0028208243
-
Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin
-
A.C. Bayly R.A. Roberts C. Dive Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin J Cell Biol 125 1994 197-203
-
(1994)
J Cell Biol
, vol.125
, pp. 197-203
-
-
Bayly, A.C.1
Roberts, R.A.2
Dive, C.3
-
169
-
-
0031695507
-
Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens
-
J.G. Christensen A.J. Gonzales R.C. et al. Cattley Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens Cell Growth Differ 9 1998 815-825
-
(1998)
Cell Growth Differ
, vol.9
, pp. 815-825
-
-
Christensen, J.G.1
Gonzales, A.J.2
Cattley, R.C.3
-
170
-
-
0032818872
-
Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice
-
J.G. Christensen E.H. Romach L.N. Healy et al. Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice Carcinogenesis 20 1999 1583-1590
-
(1999)
Carcinogenesis
, vol.20
, pp. 1583-1590
-
-
Christensen, J.G.1
Romach, E.H.2
Healy, L.N.3
-
171
-
-
17344379118
-
Apoptosis and proliferation in nongenotoxic carcinogenesis: Species differences and role of PPARalpha
-
R.A. Roberts N.H. James S.C. Hasmall et al. Apoptosis and proliferation in nongenotoxic carcinogenesis: Species differences and role of PPARalpha Toxicol Lett 112-113 2000 49-57
-
(2000)
Toxicol Lett
, vol.112-113
, pp. 49-57
-
-
Roberts, R.A.1
James, N.H.2
Hasmall, S.C.3
-
172
-
-
0031819433
-
Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)
-
R.A. Roberts N.H. James N.J. Woodyatt et al. Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha) Carcinogenesis 19 1998 43-48
-
(1998)
Carcinogenesis
, vol.19
, pp. 43-48
-
-
Roberts, R.A.1
James, N.H.2
Woodyatt, N.J.3
-
173
-
-
0031428482
-
Tumour necrosis factor alpha (TNF alpha) suppresses apoptosis and induces DNA synthesis in rodent hepatocytes: A mediator of the hepatocarcinogenicity of peroxisome proliferators?
-
M. Rolfe N.H. James R.A. Roberts Tumour necrosis factor alpha (TNF alpha) suppresses apoptosis and induces DNA synthesis in rodent hepatocytes: A mediator of the hepatocarcinogenicity of peroxisome proliferators? Carcinogenesis 18 1997 2277-2280
-
(1997)
Carcinogenesis
, vol.18
, pp. 2277-2280
-
-
Rolfe, M.1
James, N.H.2
Roberts, R.A.3
-
174
-
-
0032435382
-
Peroxisome proliferator-activated receptor (PPAR) alpha-regulated growth responses and their importance to hepatocarcinogenesis
-
N.H. James J.H. Gill R. Brindle et al. Peroxisome proliferator-activated receptor (PPAR) alpha-regulated growth responses and their importance to hepatocarcinogenesis Toxicol Lett 102-103 1998 91-96
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 91-96
-
-
James, N.H.1
Gill, J.H.2
Brindle, R.3
-
175
-
-
0035834654
-
Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver
-
S. Yu W.Q. Cao P. Kashireddy et al. Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver J Biol Chem 276 2001 42485-42491
-
(2001)
J Biol Chem
, vol.276
, pp. 42485-42491
-
-
Yu, S.1
Cao, W.Q.2
Kashireddy, P.3
-
176
-
-
9644255742
-
Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma
-
M. Hopfner A.P. Sutter A. Huether et al. Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma J Hepatol 41 2004 1008-1016
-
(2004)
J Hepatol
, vol.41
, pp. 1008-1016
-
-
Hopfner, M.1
Sutter, A.P.2
Huether, A.3
-
177
-
-
19944432263
-
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis
-
E. Schiffer C. Housset W. Cacheux et al. Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis Hepatology 41 2005 307-314
-
(2005)
Hepatology
, vol.41
, pp. 307-314
-
-
Schiffer, E.1
Housset, C.2
Cacheux, W.3
-
178
-
-
2942668459
-
Biology of the epidermal growth factor receptor family
-
C.J. Barnes R. Kumar Biology of the epidermal growth factor receptor family Cancer Treat Res 119 2004 1-13
-
(2004)
Cancer Treat Res
, vol.119
, pp. 1-13
-
-
Barnes, C.J.1
Kumar, R.2
-
179
-
-
3042782959
-
Epidermal growth factor receptor tyrosine kinase inhibitors
-
M. Ranson Epidermal growth factor receptor tyrosine kinase inhibitors Br J Cancer 90 2004 2250-2255
-
(2004)
Br J Cancer
, vol.90
, pp. 2250-2255
-
-
Ranson, M.1
-
180
-
-
0037561111
-
Inhibitors of epidermal-growth-factor receptors: A review of clinical research with a focus on non-small-cell lung cancer
-
S.S. Sridhar L. Seymour F.A. Shepherd Inhibitors of epidermal-growth-factor receptors: A review of clinical research with a focus on non-small-cell lung cancer Lancet Oncol 4 2003 397-406
-
(2003)
Lancet Oncol
, vol.4
, pp. 397-406
-
-
Sridhar, S.S.1
Seymour, L.2
Shepherd, F.A.3
-
181
-
-
4143076078
-
Targeting the epidermal growth factor receptor
-
B.F. El-Rayes P.M. LoRusso Targeting the epidermal growth factor receptor Br J Cancer 91 2004 418-424
-
(2004)
Br J Cancer
, vol.91
, pp. 418-424
-
-
El-Rayes, B.F.1
LoRusso, P.M.2
-
182
-
-
0038718522
-
Developing inhibitors of the epidermal growth factor receptor for cancer treatment
-
V. Grunwald M. Hidalgo Developing inhibitors of the epidermal growth factor receptor for cancer treatment J Natl Cancer Inst 95 2003 851-867
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 851-867
-
-
Grunwald, V.1
Hidalgo, M.2
-
183
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
N. Prenzel O.M. Fischer S. Streit et al. The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification Endocr Relat Cancer 8 2001 11-31
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
-
184
-
-
7244254665
-
Sustained activation of epidermal growth factor receptor in cholangiocarcinoma: A potent therapeutic target?
-
H. Tsubouchi Sustained activation of epidermal growth factor receptor in cholangiocarcinoma: A potent therapeutic target? J Hepatol 41 2004 859-861
-
(2004)
J Hepatol
, vol.41
, pp. 859-861
-
-
Tsubouchi, H.1
-
185
-
-
7244220245
-
Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells
-
J.H. Yoon G.Y. Gwak H.S. Lee et al. Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells J Hepatol 41 2004 808-814
-
(2004)
J Hepatol
, vol.41
, pp. 808-814
-
-
Yoon, J.H.1
Gwak, G.Y.2
Lee, H.S.3
-
186
-
-
3042563755
-
Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: Appraisal of an animal model of cholangiocarcinoma
-
Y.Y. Jan T.S. Yeh J.N. Yeh et al. Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: Appraisal of an animal model of cholangiocarcinoma Ann Surg 240 2004 89-94
-
(2004)
Ann Surg
, vol.240
, pp. 89-94
-
-
Jan, Y.Y.1
Yeh, T.S.2
Yeh, J.N.3
-
187
-
-
0029837615
-
Detection of transforming growth factor-alpha protein and messenger RNA in hepatobiliary diseases by immunohistochemical and in situ hybridization techniques
-
K. Harada T. Terada Y. Nakanuma Detection of transforming growth factor-alpha protein and messenger RNA in hepatobiliary diseases by immunohistochemical and in situ hybridization techniques Hum Pathol 27 1996 787-792
-
(1996)
Hum Pathol
, vol.27
, pp. 787-792
-
-
Harada, K.1
Terada, T.2
Nakanuma, Y.3
-
188
-
-
0035118561
-
Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma
-
Y. Ito T. Takeda Y. Sasaki et al. Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma Pathol Res Pract 197 2001 95-100
-
(2001)
Pathol Res Pract
, vol.197
, pp. 95-100
-
-
Ito, Y.1
Takeda, T.2
Sasaki, Y.3
-
189
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
R. Pai B. Soreghan I.L. Szabo et al. Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy Nat Med 8 2002 289-293
-
(2002)
Nat Med
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
-
190
-
-
0041816104
-
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
-
F.G. Buchanan D. Wang F. Bargiacchi et al. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor J Biol Chem 278 2003 35451-35457
-
(2003)
J Biol Chem
, vol.278
, pp. 35451-35457
-
-
Buchanan, F.G.1
Wang, D.2
Bargiacchi, F.3
-
191
-
-
0141593676
-
Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin
-
J. Shao S.B. Lee H. Guo et al. Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin Cancer Res 63 2003 5218-5223
-
(2003)
Cancer Res
, vol.63
, pp. 5218-5223
-
-
Shao, J.1
Lee, S.B.2
Guo, H.3
-
192
-
-
21244434022
-
Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invation through EP1 receptor-mediated activation of epidermal growth factor receptor and AKT
-
C. Han T. Wu Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invation through EP1 receptor-mediated activation of epidermal growth factor receptor and AKT J Biol Chem 2005
-
(2005)
J Biol Chem
-
-
Han, C.1
Wu, T.2
-
193
-
-
0035906821
-
Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma
-
Y. Ito T. Takeda M. Sakon et al. Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma Br J Cancer 84 2001 1377-1383
-
(2001)
Br J Cancer
, vol.84
, pp. 1377-1383
-
-
Ito, Y.1
Takeda, T.2
Sakon, M.3
-
194
-
-
10644245927
-
Vioxx withdrawal alarms cancer prevention researchers
-
C. Vanchieri Vioxx withdrawal alarms cancer prevention researchers J Natl Cancer Inst 96 2004 1734-1735
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1734-1735
-
-
Vanchieri, C.1
-
195
-
-
16544395558
-
Clinical trials. Nail-biting time for trials of COX-2 drugs
-
J. Couzin Clinical trials. Nail-biting time for trials of COX-2 drugs Science 306 2004 1673-1675
-
(2004)
Science
, vol.306
, pp. 1673-1675
-
-
Couzin, J.1
-
196
-
-
0037386939
-
Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect
-
G. Tortora R. Caputo V. Damiano et al. Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect Clin Cancer Res 9 2003 1566-1572
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1566-1572
-
-
Tortora, G.1
Caputo, R.2
Damiano, V.3
-
197
-
-
0033827119
-
Combinatorial chemoprevention of intestinal neoplasia
-
C.J. Torrance P.E. Jackson E. Montgomery et al. Combinatorial chemoprevention of intestinal neoplasia Nat Med 6 2000 1024-1028
-
(2000)
Nat Med
, vol.6
, pp. 1024-1028
-
-
Torrance, C.J.1
Jackson, P.E.2
Montgomery, E.3
-
198
-
-
0032780340
-
Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine
-
B. Ahn B.S. Han D.J. Kim et al. Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine Carcinogenesis 20 1999 1337-1344
-
(1999)
Carcinogenesis
, vol.20
, pp. 1337-1344
-
-
Ahn, B.1
Han, B.S.2
Kim, D.J.3
-
199
-
-
0033969322
-
Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
-
M. Jaiswal N.F. LaRusso L.J. Burgart et al. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism Cancer Res 60 2000 184-190
-
(2000)
Cancer Res
, vol.60
, pp. 184-190
-
-
Jaiswal, M.1
LaRusso, N.F.2
Burgart, L.J.3
-
200
-
-
0035170217
-
Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes
-
M. Jaiswal N.F. LaRusso R.A. Shapiro et al. Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes Gastroenterology 120 2001 190-199
-
(2001)
Gastroenterology
, vol.120
, pp. 190-199
-
-
Jaiswal, M.1
LaRusso, N.F.2
Shapiro, R.A.3
-
201
-
-
0037085929
-
Nitric oxide inhibits apoptosis downstream of cytochrome C release by nitrosylating caspase 9
-
N.J. Torok H. Higuchi S. Bronk et al. Nitric oxide inhibits apoptosis downstream of cytochrome C release by nitrosylating caspase 9 Cancer Res 62 2002 1648-1653
-
(2002)
Cancer Res
, vol.62
, pp. 1648-1653
-
-
Torok, N.J.1
Higuchi, H.2
Bronk, S.3
-
202
-
-
0036208533
-
The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line
-
O. Fantappie E. Masini I. Sardi et al. The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line Hepatology 35 2002 843-852
-
(2002)
Hepatology
, vol.35
, pp. 843-852
-
-
Fantappie, O.1
Masini, E.2
Sardi, I.3
-
203
-
-
0036144387
-
Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor
-
C.V. Rao C. Indranie B. Simi et al. Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor Cancer Res 62 2002 165-170
-
(2002)
Cancer Res
, vol.62
, pp. 165-170
-
-
Rao, C.V.1
Indranie, C.2
Simi, B.3
-
204
-
-
2442714172
-
Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis
-
T. Chen R.G. Nines S.M. Peschke et al. Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis Cancer Res 64 2004 3714-3717
-
(2004)
Cancer Res
, vol.64
, pp. 3714-3717
-
-
Chen, T.1
Nines, R.G.2
Peschke, S.M.3
-
205
-
-
9744228743
-
(n - 3) fatty acids and cancer therapy
-
W.E. Hardman (n - 3) fatty acids and cancer therapy J Nutr 134 2004 3427S-3430S
-
(2004)
J Nutr
, vol.134
-
-
Hardman, W.E.1
-
206
-
-
3042767902
-
Dietary long-chain n - 3 fatty acids for the prevention of cancer: A review of potential mechanisms
-
S.C. Larsson M. Kumlin M. Ingelman-Sundberg Dietary long-chain n - 3 fatty acids for the prevention of cancer: A review of potential mechanisms Am J Clin Nutr 79 2004 935-945
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 935-945
-
-
Larsson, S.C.1
Kumlin, M.2
Ingelman-Sundberg, M.3
-
207
-
-
0030817945
-
Dietary fat and colon cancer: Modulation of cyclooxygenase-2 by types and amount of dietary fat during the postinitiation stage of colon carcinogenesis
-
J. Singh R. Hamid B.S. Reddy Dietary fat and colon cancer: Modulation of cyclooxygenase-2 by types and amount of dietary fat during the postinitiation stage of colon carcinogenesis Cancer Res 57 1997 3465-3470
-
(1997)
Cancer Res
, vol.57
, pp. 3465-3470
-
-
Singh, J.1
Hamid, R.2
Reddy, B.S.3
-
208
-
-
10344263374
-
n - 3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway
-
G. Calviello F. Di Nicuolo S. Gragnoli et al. n - 3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway Carcinogenesis 25 2004 2303-2310
-
(2004)
Carcinogenesis
, vol.25
, pp. 2303-2310
-
-
Calviello, G.1
Di Nicuolo, F.2
Gragnoli, S.3
-
209
-
-
0037451893
-
Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours
-
M. Jelinska A. Tokarz R. Oledzka et al. Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours Biochim Biophys Acta 1637 2003 193-199
-
(2003)
Biochim Biophys Acta
, vol.1637
, pp. 193-199
-
-
Jelinska, M.1
Tokarz, A.2
Oledzka, R.3
-
210
-
-
0033844272
-
Modulation of liver microsomal monooxygenase system by dietary n - 6/n - 3 ratios in rat hepatocarcinogenesis
-
Y. Kim S.K. Ji H. Choi Modulation of liver microsomal monooxygenase system by dietary n - 6/n - 3 ratios in rat hepatocarcinogenesis Nutr Cancer 37 2000 65-72
-
(2000)
Nutr Cancer
, vol.37
, pp. 65-72
-
-
Kim, Y.1
Ji, S.K.2
Choi, H.3
-
211
-
-
0345491462
-
Modulating effects of diets high in omega-3 and omega-6 fatty acids in initiation and postinitiation stages of diethylnitrosamine-induced hepatocarcinogenesis in rats
-
K.M. Rahman S. Sugie K. Okamoto et al. Modulating effects of diets high in omega-3 and omega-6 fatty acids in initiation and postinitiation stages of diethylnitrosamine-induced hepatocarcinogenesis in rats Jpn J Cancer Res 90 1999 31-39
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 31-39
-
-
Rahman, K.M.1
Sugie, S.2
Okamoto, K.3
-
212
-
-
0029129410
-
Effect of fish oil on the development of AOM-induced glutathione S-transferase placental form positive hepatocellular foci in male F344 rats
-
S. Sugie K. Okamoto T. Tanaka et al. Effect of fish oil on the development of AOM-induced glutathione S-transferase placental form positive hepatocellular foci in male F344 rats Nutr Cancer 24 1995 187-195
-
(1995)
Nutr Cancer
, vol.24
, pp. 187-195
-
-
Sugie, S.1
Okamoto, K.2
Tanaka, T.3
-
213
-
-
0032753375
-
Eicosapentaenoic acid inhibits the growth of liver preneoplastic lesions and alters membrane phospholipid composition and peroxisomal beta-oxidation
-
G. Calviello P. Palozza P. Franceschelli et al. Eicosapentaenoic acid inhibits the growth of liver preneoplastic lesions and alters membrane phospholipid composition and peroxisomal beta-oxidation Nutr Cancer 34 1999 206-212
-
(1999)
Nutr Cancer
, vol.34
, pp. 206-212
-
-
Calviello, G.1
Palozza, P.2
Franceschelli, P.3
-
214
-
-
0032473553
-
Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: Effects on proliferation and apoptosis
-
G. Calviello P. Palozza E. Piccioni et al. Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: Effects on proliferation and apoptosis Int J Cancer 75 1998 699-705
-
(1998)
Int J Cancer
, vol.75
, pp. 699-705
-
-
Calviello, G.1
Palozza, P.2
Piccioni, E.3
-
215
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
D. Mukherjee S.E. Nissen E.J. Topol Risk of cardiovascular events associated with selective COX-2 inhibitors JAMA 286 2001 954-959
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
216
-
-
0037083074
-
Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac
-
W.B. White G. Faich A. Whelton et al. Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac Am J Cardiol 89 2002 425-430
-
(2002)
Am J Cardiol
, vol.89
, pp. 425-430
-
-
White, W.B.1
Faich, G.2
Whelton, A.3
-
217
-
-
6044274282
-
Coxibs and cardiovascular disease
-
G.A. Fitzgerald Coxibs and cardiovascular disease N Engl J Med 351 2004 1709-1711
-
(2004)
N Engl J Med
, vol.351
, pp. 1709-1711
-
-
Fitzgerald, G.A.1
|