Detection of transforming growth factor-α protein and messenger RNA in hepatobiliary diseases by immunohistochemical and in situ hybridization techniques

Human Pathology

Volumn 27, Issue 8, 1996, Pages 787-792

  Harada, Kenichi ^a   Terada, Tadashi ^a   Nakanuma, Yasuni ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

in situ hybridization; intrahepatic biliary tree; transforming growth factor

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; BILE DUCT CARCINOMA; CHOLELITHIASIS; CLINICAL ARTICLE; COMMON BILE DUCT STONE; DNA PROBE; HEPATOBILIARY DISEASE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; PANCREAS TUMOR; SIGNAL TRANSDUCTION;

EID: 0029837615     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(96)90450-5     Document Type: Article

References (29)

1. De Larco JE, Todaro GJ: Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci U S A 75:4001-4005, 1978
2. Derynck R: Transforming growth factor alpha. Cell 54:593-595, 1988
3. Evarts RP, Nakatsukasa H, Marsdon ER, et al: Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation. Mol Carcinogen 5:25-31, 1992
4. Schaff Z, Hsia CC, Sarosi I, et al: Overexpression of transforming growth factor-alpha in hepatocellular carcinoma and focal nodular hyperplasia from European patients. HUM PATHOL 25:644-651, 1994
5. Maher JJ, Friedman SL: Parenchymal and nonparenchymal cell interactions in the liver. Semin Liver Dis 13:13-20, 1993
6. Hsia CC, Axiotis CA, Di Bisceglie AM, et al: Transforming growth factor-alpha in human hepatocellular carcinoma and coexpression with hepatitis B surface antigen in adjacent liver. Cancer 70:1049-1056, 1992
7. Yasui W, Ji ZQ, Kuniyasu H, et al: Expression of transforming growth factor alpha in human tissues: Immunohistochemical study and Northern blot analysis. Virchows Arch [A] 421:513-519, 1992
8. Mead JE, Fausto N: Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci U S A 86:1558-1562, 1989
9. Derynck R, Goeddel DV, Ullrich A, et al: Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors. Cancer Res 47:707-712, 1987
10. Castilla A, PrietoJ, Fausto N: Transforming growth factors beta 1 and alpha in chronic liver disease: Effects of interferon alpha therapy. N Engl J Med 324:933-940, 1991
11. Arteaga CL, Hanauske AR, Clark GM, et al: Immunoreactive alpha transforming growth factor activity in effusions from cancer patients as a marker of tumor burden and patient prognosis. Cancer Res 48:5023-5028, 1988
12. Sherwin SA, Twardzik DR, Bohn WH, et al: High-molecular-weight transforming growth factor activity in the urine of patients with disseminated cancer. Cancer Res 43:403-407, 1983
13. Chuang LY, Tsai JH, Teh YC, et al: Epidermal growth factor-related transforming growth factors in the urine of patients with hepatocellular carcinoma. Hepatology 13:1112-1116, 1991
14. Scheuer PJ: Liver Biopsy Interpretation, (eds 3 and 4). London, England, Bailliers Tindall, 1980 and 1988
15. Portamann B, Popper H, Neuberger J, et al: Sequential and diagnostic features in primary biliary cirrhosis based on serial histologic study in 209 patients. Gastroenterology 88:1777-1790, 1985
16. Nakanuma Y, Ohta G: Histometric and serial section observations of the intrahepatic bile ducts in primary biliary cirrhosis. Gastroenterology 76:1326-1332, 1979
17. Danque POV, Bach N, Schaffner F, et al: HLA-DR expression in bile duct damage in hepatitis C. Mod Pathol 6:327-332, 1993
18. Lefkowitch JH, Schiff ER, Davis GL, et al: Pathological diagnosis of chronic hepatitis C: A multicenter comparative study with chronic hepatitis B. Gastroenterology 104:595-603, 1993
19. Coakley WT, James CJ: A simple linear transform for the Folin-Lowry protein calibration curve to 1.0 mg/ml. Anal Biochem 85:90-97, 1978
20. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-683, 1970
21. Masuhara M, Katyal SL, Nakamura T, et al: Differential expression of hepatocyte growth factor, transforming growth factor-alpha and transforming growth factor-beta 1 messenger RNAs in two experimental models of liver cell proliferation. Hepatology 16:1241-1249, 1992
22. Burr AW, Carpenter MR, Hines JE, et al: Intrahepatic distribution of transforming growth factor-alpha during liver regeneration following carbon tetrachloride-induced necrosis. J Pathol 170:95-100, 1993
23. Beauchamp RD, Barnard JA, McCutchen CM, et al: Localization of transforming growth factor alpha and its receptor in gastric mucosal cells: Implications for a regulatory role in acid secretion and mucosal renewal. J Clin Invest 84:1017-1023, 1989
24. Chang LC, Chou MY, Chow P, et al: Detection of transforming growth factor-alpha messenger RNA in normal and chemically transformed hamster oral epithelium by in situ hybridization. Cancer Res 49:6700-6707, 1989
25. Meyer DH, Bachem MG, Gressner AM: Bidirectional effects of Kupffer cells on hepatocyte proliferation in vitro. FEBS Lett 283:150-154, 1991
26. Nakanuma Y, Harada K: Florid duct lesion in primary biliary cirrhosis shows highly proliferative activities. J Hepatol 19:216-221, 1993
27. van Eyken P, Desmet VJ: Cytokeratins and the liver. Liver 13:113-122, 1993
28. Uchida T, Peters RL: The nature and origin of proliferated bile ductules in alcoholic liver disease. Am J Clin Pathol 79:326-333, 1983
29. Sell S: Liver stem cells. Mod Pathol 7:105-112, 1994