-
1
-
-
0034799139
-
A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
-
Ciardiello, F., and Tortora, G. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin. Cancer Res., 7: 2958-2970, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2958-2970
-
-
Ciardiello, F.1
Tortora, G.2
-
2
-
-
0029565543
-
cAMP-dependent protein kinase: Role in normal and malignant growth
-
Cho-Chung, Y. S., Pepe, S., Clair, T., Budillon, A., and Nesterova, M. cAMP-dependent protein kinase: role in normal and malignant growth. Crit. Rev. Oncol. Hematol., 21: 33-61, 1995.
-
(1995)
Crit. Rev. Oncol. Hematol.
, vol.21
, pp. 33-61
-
-
Cho-Chung, Y.S.1
Pepe, S.2
Clair, T.3
Budillon, A.4
Nesterova, M.5
-
3
-
-
0033063774
-
The epidermal growth factor receptor and its inhibition in cancer therapy
-
Woodburn, J. R. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol. Ther., 82: 241-250, 1999.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 241-250
-
-
Woodburn, J.R.1
-
4
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an EGFR-selective tyrosine kinase inhibitor
-
Ciardiello, F., Caputo, R., Bianco, R., Damiano, V., Pomatico, G., De Placido, S., Bianco, A. R., and Tortora, G. Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an EGFR-selective tyrosine kinase inhibitor. Clin. Cancer Res., 6: 2053-2063, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Pomatico, G.5
De Placido, S.6
Bianco, A.R.7
Tortora, G.8
-
5
-
-
0034896362
-
Inhibition of growth factors production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
-
Ciardiello, F., Caputo, R., Bianco, R., Damiano, V., Fontanini, G., Cuccato, S., De Placido, S., Bianco, A. R., and Tortora, G. Inhibition of growth factors production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin. Cancer Res., 7: 1459-1465, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1459-1465
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Fontanini, G.5
Cuccato, S.6
De Placido, S.7
Bianco, A.R.8
Tortora, G.9
-
6
-
-
0033816198
-
Targeting of epidermal growth factor receptor and protein kinase A: Molecular basis and therapeutic applications
-
Tortora, G., and Ciardiello, F. Targeting of epidermal growth factor receptor and protein kinase A: molecular basis and therapeutic applications. Ann. Oncol., 11: 777-783, 2000.
-
(2000)
Ann. Oncol.
, vol.11
, pp. 777-783
-
-
Tortora, G.1
Ciardiello, F.2
-
7
-
-
0030614954
-
The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor
-
Tortora, G., Damiano, V., Bianco, C., Baldassarre, G., Bianco, A. R., Lanfrancone, L., Pelicci, P. G., and Ciardiello, F. The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor. Oncogene, 14: 923-928, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 923-928
-
-
Tortora, G.1
Damiano, V.2
Bianco, C.3
Baldassarre, G.4
Bianco, A.R.5
Lanfrancone, L.6
Pelicci, P.G.7
Ciardiello, F.8
-
8
-
-
0036187489
-
Protein kinase a type I: A target for cancer therapy
-
Tortora, G., and Ciardiello, F. Protein kinase a type I: a target for cancer therapy. Clin. Cancer Res., 8: 303-304, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 303-304
-
-
Tortora, G.1
Ciardiello, F.2
-
9
-
-
0029050664
-
A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth
-
Nesterova, M., and Cho Chung, Y. S. A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth. Nat. Med., 1: 528-533, 1997.
-
(1997)
Nat. Med.
, vol.1
, pp. 528-533
-
-
Nesterova, M.1
Cho Chung, Y.S.2
-
10
-
-
0030729721
-
Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A
-
Tortora, G., Caputo, R., Damiano, V., Bianco, R., Pepe, S., Bianco, A. R., Jiang, Z., Agrawal, S., and Ciardiello, F. Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A. Proc. Natl. Acad. Sci. USA, 94: 12586-12591, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12586-12591
-
-
Tortora, G.1
Caputo, R.2
Damiano, V.3
Bianco, R.4
Pepe, S.5
Bianco, A.R.6
Jiang, Z.7
Agrawal, S.8
Ciardiello, F.9
-
11
-
-
0033598705
-
Antitumor activity and pharmacokinetics of a mixed-backbone oligonucleotide targeted to the RIα subunit of protein kinase A following oral administration
-
Wang, H., Cai, Q., Zeng, X., Yu, D., Agrawal, S., and Zhang, R. Antitumor activity and pharmacokinetics of a mixed-backbone oligonucleotide targeted to the RIα subunit of protein kinase A following oral administration. Proc. Natl. Acad. Sci. USA, 96: 13989-13994, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13989-13994
-
-
Wang, H.1
Cai, Q.2
Zeng, X.3
Yu, D.4
Agrawal, S.5
Zhang, R.6
-
12
-
-
0034130453
-
Oral antisense targeting protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis and growth factors production
-
Tortora, G., Bianco, R., Damiano, V., Fontanini, G., De Placido, S., Bianco, A. R., and Ciardiello, F. Oral antisense targeting protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis and growth factors production. Clin. Cancer Res., 6: 2506-2512, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2506-2512
-
-
Tortora, G.1
Bianco, R.2
Damiano, V.3
Fontanini, G.4
De Placido, S.5
Bianco, A.R.6
Ciardiello, F.7
-
13
-
-
16144362509
-
Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A
-
Ciardiello, F., Damiano, V., Bianco, R., Bianco, C., Fontanini, G., De Laurentiis, M., De Placido, S., Mendelsohn, J., Bianco, A. R., and Tortora, G. Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A. J. Natl. Cancer Inst. (Bethesda), 88: 1770-1776, 1996.
-
(1996)
J. Natl. Cancer Inst. (Bethesda)
, vol.88
, pp. 1770-1776
-
-
Ciardiello, F.1
Damiano, V.2
Bianco, R.3
Bianco, C.4
Fontanini, G.5
De Laurentiis, M.6
De Placido, S.7
Mendelsohn, J.8
Bianco, A.R.9
Tortora, G.10
-
14
-
-
0036177671
-
Cyclooxygenase-2: A therapeutic target
-
Turini, M. E., and DuBois, R. N. Cyclooxygenase-2: a therapeutic target. Annu. Rev. Med., 53: 35-57, 2002.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 35-57
-
-
Turini, M.E.1
DuBois, R.N.2
-
15
-
-
0033761153
-
Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients
-
Masunaga, R., Kohno, H., Dhar, D. K., Ohno, S., Shibakita, M., Kinugasa, S., Yoshimura, H., Tachibana, M., Kubota, H., and Nagasue, N. Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients. Clin. Cancer Res., 6: 4064-4068, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4064-4068
-
-
Masunaga, R.1
Kohno, H.2
Dhar, D.K.3
Ohno, S.4
Shibakita, M.5
Kinugasa, S.6
Yoshimura, H.7
Tachibana, M.8
Kubota, H.9
Nagasue, N.10
-
16
-
-
0035126879
-
Cyclooxygenase-2 is overexpressed in human cervical cancer
-
Kulkarni, S., Rader, J. S., Zhang, F., Liapis, H., Koki, A. T., Masferrer, J. L., Subbaramaiah, K., and Dannenberg, A. J. Cyclooxygenase-2 is overexpressed in human cervical cancer. Clin. Cancer Res., 7: 429-434, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 429-434
-
-
Kulkarni, S.1
Rader, J.S.2
Zhang, F.3
Liapis, H.4
Koki, A.T.5
Masferrer, J.L.6
Subbaramaiah, K.7
Dannenberg, A.J.8
-
17
-
-
0034901568
-
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
-
Khuri, F. R., Wu, H., Lee, J. J., Kemp, B. L., Lotan, R., Lippman, S. M., Feng, L., Hong, W. K., and Xu, X-C. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin. Cancer Res., 7: 861-867, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 861-867
-
-
Khuri, F.R.1
Wu, H.2
Lee, J.J.3
Kemp, B.L.4
Lotan, R.5
Lippman, S.M.6
Feng, L.7
Hong, W.K.8
Xu, X.-C.9
-
18
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer, J. L., Leahy, K. M., Koki, A. T., Zweifel, B. S., Settle, S. L., Woerner, M., Edwards, D. A., Flickinger, A. G., Moore, R. J., and Seibert, K. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res., 60: 1306-1311, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
Zweifel, B.S.4
Settle, S.L.5
Woerner, M.6
Edwards, D.A.7
Flickinger, A.G.8
Moore, R.J.9
Seibert, K.10
-
19
-
-
0035902487
-
Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration
-
Rudnick, D. A., Perlmutter, D. H., and Muglia, L. J. Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration. Proc. Natl. Acad. Sci., USA, 98: 8885-8890, 2001.
-
(2001)
Proc. Natl. Acad. Sci., USA
, vol.98
, pp. 8885-8890
-
-
Rudnick, D.A.1
Perlmutter, D.H.2
Muglia, L.J.3
-
20
-
-
0033827119
-
Combinatorial chemoprevention of intestinal neoplasia
-
Torrance, C. J., Jackson, P. E., Montgomery, E., Kinzler, K. W., Vogelstein, B., Wissner, A., Nunes, M., Frost, P., and Discafani, C. M. Combinatorial chemoprevention of intestinal neoplasia. Nat. Med., 6: 1024-1028, 2000.
-
(2000)
Nat. Med.
, vol.6
, pp. 1024-1028
-
-
Torrance, C.J.1
Jackson, P.E.2
Montgomery, E.3
Kinzler, K.W.4
Vogelstein, B.5
Wissner, A.6
Nunes, M.7
Frost, P.8
Discafani, C.M.9
-
21
-
-
0033451177
-
COX-2 inhibitors. A new class of antiangiogenic agents
-
Masferrer, J. L., Koki, A., and Seibert, K. COX-2 inhibitors. A new class of antiangiogenic agents. Ann. N. Y. Acad. Sci., 889: 84-86, 1999.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.889
, pp. 84-86
-
-
Masferrer, J.L.1
Koki, A.2
Seibert, K.3
-
23
-
-
0029127219
-
Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
-
Weidner, N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res. Treat., 36: 169-180, 1995.
-
(1995)
Breast Cancer Res. Treat.
, vol.36
, pp. 169-180
-
-
Weidner, N.1
-
25
-
-
0031039923
-
Transforming growth factor α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP2-dependent DNA binding and transactivation
-
Gille, J., Swerlick, R. A., and Caughman, S. W. Transforming growth factor α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP2-dependent DNA binding and transactivation. EMBO J., 16: 750-759, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
26
-
-
0030888688
-
8-Chloro-cAMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer
-
Bianco, C., Tortora, G., Baldassarre, G., Caputo, R., Fontanini, G., Chinè, S., Bianco, A. R., and Ciardiello, F. 8-chloro-cAMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer. Clin. Cancer Res., 3: 439-448, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 439-448
-
-
Bianco, C.1
Tortora, G.2
Baldassarre, G.3
Caputo, R.4
Fontanini, G.5
Chinè, S.6
Bianco, A.R.7
Ciardiello, F.8
-
27
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii, M., Kawano, S., Tsujii, S., Sawaoka, H., Hori, M., and DuBois, R. N. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell, 93: 705-716, 1998.
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsujii, S.3
Sawaoka, H.4
Hori, M.5
DuBois, R.N.6
-
28
-
-
0030952695
-
Cyclooxygenase-2 expression in colon cancer cells increases metastatic potential
-
Tsujii, M., Kawano, S., and DuBois, R. N. Cyclooxygenase-2 expression in colon cancer cells increases metastatic potential. Proc. Natl. Acad. Sci., USA, 94: 3326-3340, 1997.
-
(1997)
Proc. Natl. Acad. Sci., USA
, vol.94
, pp. 3326-3340
-
-
Tsujii, M.1
Kawano, S.2
DuBois, R.N.3
-
29
-
-
0034530889
-
The contributions of cyclooxygenase-2 to tumor angiogenesis
-
Gately, S. The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev., 19: 19-27, 2000.
-
(2000)
Cancer Metastasis Rev.
, vol.19
, pp. 19-27
-
-
Gately, S.1
-
30
-
-
0035674731
-
Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity
-
Tortora, G., Caputo, R., Damiano, V., Fontanini, G., Melisi, D., Veneziani, B. M., Zunino, F., Bianco, A. R., and Ciardiello, F. Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. Clin. Cancer Res., 7: 4156-4163, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 4156-4163
-
-
Tortora, G.1
Caputo, R.2
Damiano, V.3
Fontanini, G.4
Melisi, D.5
Veneziani, B.M.6
Zunino, F.7
Bianco, A.R.8
Ciardiello, F.9
-
31
-
-
0034055374
-
Inhibition of cyclooxygenase-2 decreases DNA synthesis induced by platelet-derived growth factor in Swiss 3T3 fibroblasts
-
Castano, E., Bartrons, R., and Gil, J. Inhibition of cyclooxygenase-2 decreases DNA synthesis induced by platelet-derived growth factor in Swiss 3T3 fibroblasts. J. Pharmacol. Exp. Ther., 293: 509-513, 2000.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 509-513
-
-
Castano, E.1
Bartrons, R.2
Gil, J.3
|