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Volumn 19, Issue 1, 1998, Pages 43-48

Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPARα)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NAFENOPIN; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENOBARBITAL; RETINOID X RECEPTOR;

EID: 0031819433     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.1.43     Document Type: Article
Times cited : (137)

References (35)
  • 1
    • 0026100678 scopus 로고
    • Peroxisome proliferation and non-genotoxic carcinogenesis: Commentary on a symposium
    • Moody, D.E., Reddy, J.K., Lake, B.G., Popp, J.A. and Reese, D.H. (1991) Peroxisome proliferation and non-genotoxic carcinogenesis: commentary on a symposium. Fund. Appl. Toxicol., 6, 233-248.
    • (1991) Fund. Appl. Toxicol. , vol.6 , pp. 233-248
    • Moody, D.E.1    Reddy, J.K.2    Lake, B.G.3    Popp, J.A.4    Reese, D.H.5
  • 2
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators. Evaluation of the risk of hypolidaemic drugs and industrial plasticizers to humans
    • Reddy, J.K. and Lalwani, N.D. (1983) Carcinogenesis by hepatic peroxisome proliferators. Evaluation of the risk of hypolidaemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol., 12, 1-58.
    • (1983) Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwani, N.D.2
  • 4
    • 0022924249 scopus 로고
    • Peroxisome proliferation due to di(2-ethyl) phthalate: Species differences and possible mechanisms
    • Elcombe, C.R. and Mitchell, A. (1986) Peroxisome proliferation due to di(2-ethyl) phthalate: species differences and possible mechanisms. Environ. Hlth Perspect., 70, 211-219.
    • (1986) Environ. Hlth Perspect. , vol.70 , pp. 211-219
    • Elcombe, C.R.1    Mitchell, A.2
  • 6
    • 0025163524 scopus 로고
    • Too many rodent carcinogens: Mitogenesis increases mutagenesis
    • Ames, B.N. and Gold, L.S. (1990) Too many rodent carcinogens: mitogenesis increases mutagenesis. Science, 249, 970-971.
    • (1990) Science , vol.249 , pp. 970-971
    • Ames, B.N.1    Gold, L.S.2
  • 7
    • 0018400840 scopus 로고
    • Adaptive liver growth induced by xenobiotic compounds: Its nature and mechanism
    • Schulte-Hermann, R. (1979) Adaptive liver growth induced by xenobiotic compounds: its nature and mechanism. Arch. Toxicol. Suppl., 2, 113-124.
    • (1979) Arch. Toxicol. Suppl. , vol.2 , pp. 113-124
    • Schulte-Hermann, R.1
  • 9
    • 0028931999 scopus 로고
    • Apoptosis: Regulation and relevance to toxicology
    • Alison, M.R. and Sarraf, C.E. (1995) Apoptosis: regulation and relevance to toxicology. Hum. Exp. Toxicol., 14, 234-247.
    • (1995) Hum. Exp. Toxicol. , vol.14 , pp. 234-247
    • Alison, M.R.1    Sarraf, C.E.2
  • 10
    • 0028208243 scopus 로고
    • Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator, nafenopin
    • Bayly, A.C., Roberts, R.A. and Dive, C. (1994) Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator, nafenopin. J. Cell Biol., 125, 197-203.
    • (1994) J. Cell Biol. , vol.125 , pp. 197-203
    • Bayly, A.C.1    Roberts, R.A.2    Dive, C.3
  • 11
    • 0029776373 scopus 로고    scopus 로고
    • Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than with suppression of apoptosis
    • James, N.H. and Roberts, R.A. (1996) Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than with suppression of apoptosis. Carcinogenesis, 17, 1623-1632.
    • (1996) Carcinogenesis , vol.17 , pp. 1623-1632
    • James, N.H.1    Roberts, R.A.2
  • 12
    • 0030580220 scopus 로고    scopus 로고
    • Reduced expression of mature TGFβ1 correlates with the suppression of rat hepatocyte apoptosis by the peroxisome proliferator, nafenopin
    • Strange, J. and Roberts, R.A. (1996) Reduced expression of mature TGFβ1 correlates with the suppression of rat hepatocyte apoptosis by the peroxisome proliferator, nafenopin. Mutat. Res., 372, 107-113.
    • (1996) Mutat. Res. , vol.372 , pp. 107-113
    • Strange, J.1    Roberts, R.A.2
  • 13
    • 0029081713 scopus 로고
    • Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different discrete hepatocyte populations
    • Roberts, R.A., Soames, A.R., Gill, J.H., James, N.H. and Wheeldon, E.B. (1995) Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different discrete hepatocyte populations. Carcinogenesis, 16, 1693-1698.
    • (1995) Carcinogenesis , vol.16 , pp. 1693-1698
    • Roberts, R.A.1    Soames, A.R.2    Gill, J.H.3    James, N.H.4    Wheeldon, E.B.5
  • 14
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann, I. and Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347, 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 15
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf, D.J., Thummel, C., Beato, M. et al. (1995) The nuclear receptor superfamily: the second decade. Cell, 83, 835-839.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 16
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleitrophic effects of peroxisome proliferators
    • Lee, S.S.-T., Pineau, T., Drago, J., Lee, E.J., Owens, J.O., Kroetz, D.L., Fernandez-Salguero, P.M., Westphal, H. and Gonzalez, F.J. (1995) Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleitrophic effects of peroxisome proliferators. Mol. Cell. Biol., 15, 3012-3022.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.-T.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.O.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 17
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer, S.A., Umesono, K., Noonan, D.J., Heyman, R.A. and Evans, R.M. (1992) Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature, 358, 771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 18
    • 0027525576 scopus 로고
    • The peroxisome proliferator-activated receptor: Retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
    • Issemann, I., Prince, R.A., Tugwood, J.D. and Green, S. (1993) The peroxisome proliferator-activated receptor: retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrin., 11, 37-47.
    • (1993) J. Mol. Endocrin. , vol.11 , pp. 37-47
    • Issemann, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 19
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl Coa oxidase gene
    • Tugwood, J.D., Issemann, I., Anderson, R.G., Bundell, K.R., McPheat, W.L. and Green, S. (1992) The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO J., 11, 433-439.
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 20
    • 0028033268 scopus 로고
    • The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
    • Gulick, T., Cresci, S., Caira, T., Moore, D.D. and Kelly, D.P. (1994) The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc. Natl Acad. Sci. USA, 91, 11012-11016.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11012-11016
    • Gulick, T.1    Cresci, S.2    Caira, T.3    Moore, D.D.4    Kelly, D.P.5
  • 21
    • 0028953133 scopus 로고
    • Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
    • Aldridge, T.C., Tugwood, J.D. and Green, S. (1995) Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription. Biochem. J., 306, 473-479.
    • (1995) Biochem. J. , vol.306 , pp. 473-479
    • Aldridge, T.C.1    Tugwood, J.D.2    Green, S.3
  • 22
    • 0026730908 scopus 로고
    • The peroxisome proliferator activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid w-hydroxylase by clofibric acid
    • Muerhoff, A.S., Griffin, K.J. and Johnson, E.F. (1992) The peroxisome proliferator activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid w-hydroxylase by clofibric acid. J. Biol. Chem., 267, 19051-19053.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19051-19053
    • Muerhoff, A.S.1    Griffin, K.J.2    Johnson, E.F.3
  • 23
    • 0021770224 scopus 로고
    • Compilation and analysis of sequencesupstream from the translational start site in eukaryotic mRNAs
    • Kozak, M. (1984) Compilation and analysis of sequencesupstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res., 2, 857-872.
    • (1984) Nucleic Acids Res. , vol.2 , pp. 857-872
    • Kozak, M.1
  • 24
    • 0015752890 scopus 로고
    • Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion
    • Seglen, P.O. (1973) Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion. Exp. Cell Res., 82, 391-398.
    • (1973) Exp. Cell Res. , vol.82 , pp. 391-398
    • Seglen, P.O.1
  • 25
    • 0004282518 scopus 로고
    • SAS Institute Incorporated, New York
    • Cary, N.C. (1989) SAS/STAT User's Guide. SAS Institute Incorporated, New York.
    • (1989) SAS/STAT User's Guide
    • Cary, N.C.1
  • 26
    • 0028037369 scopus 로고
    • Molecular mechanisms of dominant negative activity by nuclear hormone receptors
    • Yen, P.M. and Chin, W.W. (1994) Molecular mechanisms of dominant negative activity by nuclear hormone receptors. Mol. Endocrinol., 8, 1450-1454.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1450-1454
    • Yen, P.M.1    Chin, W.W.2
  • 27
    • 0028916339 scopus 로고
    • The role of Barbie box sequences as cis-acting elements involved in the barbiturate-mediated induction of cytochromes P450BM-1 and P450BM-3 in Bacillus megaterium
    • Liang, Q., He, J.S. and Fulco, J.S. (1995)The role of Barbie box sequences as cis-acting elements involved in the barbiturate-mediated induction of cytochromes P450BM-1 and P450BM-3 in Bacillus megaterium. J. Biol. Chem., 270, 4438-4450.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4438-4450
    • Liang, Q.1    He, J.S.2    Fulco, J.S.3
  • 28
    • 0031428482 scopus 로고    scopus 로고
    • Tumour necrosis factor α (TNF-α) suppreses apoptosis and induces S-phase in rodent hepatocytes: A mediator of the hepatocarcinogenicity of peroxisome proliferators?
    • Rolfe, M., James, N.H. and Roberts, R.A. (1997) Tumour necrosis factor α (TNF-α) suppreses apoptosis and induces S-phase in rodent hepatocytes: a mediator of the hepatocarcinogenicity of peroxisome proliferators? Carcinogenesis, 18, 2277-2280.
    • (1997) Carcinogenesis , vol.18 , pp. 2277-2280
    • Rolfe, M.1    James, N.H.2    Roberts, R.A.3
  • 29
    • 0025051058 scopus 로고
    • Biologically active products of stimulated liver macrophages (Kupffer cells)
    • Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem., 192, 245-261.
    • (1990) Eur. J. Biochem. , vol.192 , pp. 245-261
    • Decker, K.1
  • 30
    • 0030070481 scopus 로고    scopus 로고
    • Peroxisome proliferators activate kupffer cells in vivo
    • Bojes, H.K. and Thurman, R.G. (1996) Peroxisome proliferators activate kupffer cells in vivo. Cancer Res., 56, 1-4.
    • (1996) Cancer Res. , vol.56 , pp. 1-4
    • Bojes, H.K.1    Thurman, R.G.2
  • 31
    • 0031417341 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor-alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator WY-14,643
    • Bojes, H.K., Germolec, D.R., Simeonova, P., Bruccolrei, A., Schoonhoven, R., Luster, M.I. and Thurman, R.G. (1997) Antibodies to tumor necrosis factor-alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator WY-14,643. Carcinogenesis, 18, 669-674.
    • (1997) Carcinogenesis , vol.18 , pp. 669-674
    • Bojes, H.K.1    Germolec, D.R.2    Simeonova, P.3    Bruccolrei, A.4    Schoonhoven, R.5    Luster, M.I.6    Thurman, R.G.7
  • 32
    • 0025652794 scopus 로고
    • Isolation, purification and characterisation of liver cell types
    • Hendriks, H.F.J., Brouwer, A. and Knook, D.L. (1991) Isolation, purification and characterisation of liver cell types. Methods Enzymol., 190, 49-58.
    • (1991) Methods Enzymol. , vol.190 , pp. 49-58
    • Hendriks, H.F.J.1    Brouwer, A.2    Knook, D.L.3
  • 33
    • 0000886373 scopus 로고
    • Mechanism-based risk assessment of peroxisome proliferating rodent hepatocarcinogens
    • Reddy, J.K., Suga, T., Mannaerts, G.P., Lazarow, P.B. and Subramani, S. (eds) The New York Academy of Sciences, New York
    • Williams, G.M. and Perrone, C. (1995) Mechanism-based risk assessment of peroxisome proliferating rodent hepatocarcinogens. In Reddy, J.K., Suga, T., Mannaerts, G.P., Lazarow, P.B. and Subramani, S. (eds) Peroxisomes: Biology and Role in Toxicology and Disease. The New York Academy of Sciences, New York, pp. 554-572.
    • (1995) Peroxisomes: Biology and Role in Toxicology and Disease , pp. 554-572
    • Williams, G.M.1    Perrone, C.2
  • 34
    • 0027191040 scopus 로고
    • cDNA cloning, chromosomal mapping and functional characterisation of the human peroxisome proliferator-activated receptor
    • Sher, T., Yi, H.F., McBride, W. and Gonzalez, F.J. (1993) cDNA cloning, chromosomal mapping and functional characterisation of the human peroxisome proliferator-activated receptor. Biochemistry, 32, 5598-5604.
    • (1993) Biochemistry , vol.32 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    McBride, W.3    Gonzalez, F.J.4
  • 35
    • 0027959552 scopus 로고
    • Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators
    • Mukherjee, R., Jow, L., Noonan, D. and McDonnell, D.P. (1994) Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J. Steroid Biochem., 51, 157-166.
    • (1994) J. Steroid Biochem. , vol.51 , pp. 157-166
    • Mukherjee, R.1    Jow, L.2    Noonan, D.3    McDonnell, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.