-
1
-
-
0020596551
-
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
-
F. Barre-Sinoussi, J.C. Chermann, F. Rey, M.T. Nugeyre, S. Chamaret, and J. Gruest Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS) Science 220 1983 868 871
-
(1983)
Science
, vol.220
, pp. 868-871
-
-
Barre-Sinoussi, F.1
Chermann, J.C.2
Rey, F.3
Nugeyre, M.T.4
Chamaret, S.5
Gruest, J.6
-
2
-
-
0020932613
-
Isolation of a new retrovirus in a patient at risk for acquired immunodeficiency syndrome
-
J.C. Chermann, F. Barre-Sinoussi, C. Dauguet, F. Brun-Vezinet, C. Rouzioux, and W. Rozenbaum Isolation of a new retrovirus in a patient at risk for acquired immunodeficiency syndrome Antibiot Chemother 32 1983 48 53
-
(1983)
Antibiot Chemother
, vol.32
, pp. 48-53
-
-
Chermann, J.C.1
Barre-Sinoussi, F.2
Dauguet, C.3
Brun-Vezinet, F.4
Rouzioux, C.5
Rozenbaum, W.6
-
3
-
-
0037624182
-
Twenty years of therapy for HIV-1 infection
-
R.J. Pomerantz, and D.L. Horn Twenty years of therapy for HIV-1 infection Nat Med 9 2003 867 873
-
(2003)
Nat Med
, vol.9
, pp. 867-873
-
-
Pomerantz, R.J.1
Horn, D.L.2
-
4
-
-
13344278708
-
The emerging genetic diversity of HIV. the importance of global surveillance for diagnostics, research, and prevention
-
D.J. Hu, T.J. Dondero, M.A. Rayfield, J.R. George, G. Schochetman, and H.W. Jaffe The emerging genetic diversity of HIV. The importance of global surveillance for diagnostics, research, and prevention JAMA 275 1996 210 216
-
(1996)
JAMA
, vol.275
, pp. 210-216
-
-
Hu, D.J.1
Dondero, T.J.2
Rayfield, M.A.3
George, J.R.4
Schochetman, G.5
Jaffe, H.W.6
-
5
-
-
0025193794
-
Isolation and partial characterization of an unusual human immunodeficiency retrovirus from two persons of West-central African origin
-
R. De Leys, B. Vanderborght, M. Vanden Haesevelde, L. Heyndrickx, A. van Geel, and C. Wauters Isolation and partial characterization of an unusual human immunodeficiency retrovirus from two persons of West-central African origin J Virol 64 1990 1207 1216
-
(1990)
J Virol
, vol.64
, pp. 1207-1216
-
-
De Leys, R.1
Vanderborght, B.2
Vanden Haesevelde, M.3
Heyndrickx, L.4
Van Geel, A.5
Wauters, C.6
-
7
-
-
0035912248
-
Gulliver's travels in HIVland
-
R.A. Weiss Gulliver's travels in HIVland Nature 410 2001 963 967
-
(2001)
Nature
, vol.410
, pp. 963-967
-
-
Weiss, R.A.1
-
8
-
-
0036176509
-
The challenge of viral reservoirs in HIV-1 infection
-
J.N. Blankson, D. Persaud, and R.F. Siliciano The challenge of viral reservoirs in HIV-1 infection Annu Rev Med 53 2002 557 593
-
(2002)
Annu Rev Med
, vol.53
, pp. 557-593
-
-
Blankson, J.N.1
Persaud, D.2
Siliciano, R.F.3
-
9
-
-
0033613070
-
Latent reservoirs of HIV: Obstacles to the eradication of virus
-
T.W. Chun, and A.S. Fauci Latent reservoirs of HIV: obstacles to the eradication of virus Proc Natl Acad Sci USA 96 1999 10958 10961
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10958-10961
-
-
Chun, T.W.1
Fauci, A.S.2
-
10
-
-
0036289210
-
Macrophages and HIV infection: Therapeutical approaches toward this strategic virus reservoir
-
S. Aquaro, R. Calio, J. Balzarini, M.C. Bellocchi, E. Garaci, and C.F. Perno Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir Antiviral Res 55 2002 209 225
-
(2002)
Antiviral Res
, vol.55
, pp. 209-225
-
-
Aquaro, S.1
Calio, R.2
Balzarini, J.3
Bellocchi, M.C.4
Garaci, E.5
Perno, C.F.6
-
11
-
-
0035912249
-
HIV chemotherapy
-
D.D. Richman HIV chemotherapy Nature 410 2001 995 1001
-
(2001)
Nature
, vol.410
, pp. 995-1001
-
-
Richman, D.D.1
-
12
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
X. Wei, J.M. Decker, H. Liu, Z. Zhang, R.B. Arani, and J.M. Kilby Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy Antimicrob Agents Chemother 46 2002 1896 1905
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
Zhang, Z.4
Arani, R.B.5
Kilby, J.M.6
-
13
-
-
0030932188
-
Chemokine receptors as fusion cofactors for human immunodeficiency virus type 1 (HIV-1)
-
B.J. Doranz, J.F. Berson, J. Rucker, and R.W. Doms Chemokine receptors as fusion cofactors for human immunodeficiency virus type 1 (HIV-1) Immunol Res 16 1997 15 28
-
(1997)
Immunol Res
, vol.16
, pp. 15-28
-
-
Doranz, B.J.1
Berson, J.F.2
Rucker, J.3
Doms, R.W.4
-
14
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Y. Feng, C.C. Broder, P.E. Kennedy, and E.A. Berger HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor Science 272 1996 872 877
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
15
-
-
0030018156
-
CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
-
G. Alkhatib, C. Combadiere, C.C. Broder, Y. Feng, P.E. Kennedy, and P.M. Murphy CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1 Science 272 1996 1955 1958
-
(1996)
Science
, vol.272
, pp. 1955-1958
-
-
Alkhatib, G.1
Combadiere, C.2
Broder, C.C.3
Feng, Y.4
Kennedy, P.E.5
Murphy, P.M.6
-
16
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
H. Deng, R. Liu, W. Ellmeier, S. Choe, D. Unutmaz, and M. Burkhart Identification of a major co-receptor for primary isolates of HIV-1 Nature 381 1996 661 666
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
Choe, S.4
Unutmaz, D.5
Burkhart, M.6
-
17
-
-
15844389650
-
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
-
T. Dragic, V. Litwin, G.P. Allaway, S.R. Martin, Y. Huang, and K.A. Nagashima HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5 Nature 381 1996 667 673
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
Martin, S.R.4
Huang, Y.5
Nagashima, K.A.6
-
19
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
M. Samson, F. Libert, B.J. Doranz, J. Rucker, C. Liesnard, and C.M. Farber Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene Nature 382 1996 722 725
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.M.6
-
20
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
R. Liu, W.A. Paxton, S. Choe, D. Ceradini, S.R. Martin, and R. Horuk Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection Cell 86 1996 367 377
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
-
21
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
M. Dean, M. Carrington, C. Winkler, G.A. Huttley, M.W. Smith, and R. Allikmets Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study Science 273 1996 1856 1862
-
(1996)
Science
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
-
22
-
-
0032499260
-
Chemokines and leukocyte traffic
-
M. Baggiolini Chemokines and leukocyte traffic Nature 392 1998 565 568
-
(1998)
Nature
, vol.392
, pp. 565-568
-
-
Baggiolini, M.1
-
23
-
-
0036262275
-
International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature
-
P.M. Murphy International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature Pharmacol Rev 54 2002 227 229
-
(2002)
Pharmacol Rev
, vol.54
, pp. 227-229
-
-
Murphy, P.M.1
-
25
-
-
0028324332
-
High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR
-
P.J. Lodi, D.S. Garrett, J. Kuszewski, M.L. Tsang, J.A. Weatherbee, and W.J. Leonard High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR Science 263 1994 1762 1767
-
(1994)
Science
, vol.263
, pp. 1762-1767
-
-
Lodi, P.J.1
Garrett, D.S.2
Kuszewski, J.3
Tsang, M.L.4
Weatherbee, J.A.5
Leonard, W.J.6
-
26
-
-
0027372505
-
A receptor for the malarial parasite Plasmodium vivax: The erythrocyte chemokine receptor
-
R. Horuk, C.E. Chitnis, W.C. Darbonne, T.J. Colby, A. Rybicki, and T.J. Hadley A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor Science 261 1993 1182 1184
-
(1993)
Science
, vol.261
, pp. 1182-1184
-
-
Horuk, R.1
Chitnis, C.E.2
Darbonne, W.C.3
Colby, T.J.4
Rybicki, A.5
Hadley, T.J.6
-
27
-
-
0031434809
-
Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6
-
R.J. Nibbs, S.M. Wylie, J. Yang, N.R. Landau, and G.J. Graham Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6 J Biol Chem 272 1997 32078 32083
-
(1997)
J Biol Chem
, vol.272
, pp. 32078-32083
-
-
Nibbs, R.J.1
Wylie, S.M.2
Yang, J.3
Landau, N.R.4
Graham, G.J.5
-
28
-
-
0036099747
-
Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: Comparison to human CCX-CKR
-
J.R. Townson, and R.J. Nibbs Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR Eur J Immunol 32 2002 1230 1241
-
(2002)
Eur J Immunol
, vol.32
, pp. 1230-1241
-
-
Townson, J.R.1
Nibbs, R.J.2
-
29
-
-
0029060187
-
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation
-
A.D. Luster, S.M. Greenberg, and P. Leder The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation J Exp Med 182 1995 219 231
-
(1995)
J Exp Med
, vol.182
, pp. 219-231
-
-
Luster, A.D.1
Greenberg, S.M.2
Leder, P.3
-
30
-
-
0026694563
-
Endothelial cell binding of NAP-1/IL-8: Role in neutrophil emigration
-
A. Rot Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration Immunol Today 13 1992 291 294
-
(1992)
Immunol Today
, vol.13
, pp. 291-294
-
-
Rot, A.1
-
31
-
-
0033613247
-
Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses
-
G.S. Kuschert, F. Coulin, C.A. Power, A.E. Proudfoot, R.E. Hubbard, and A.J. Hoogewerf Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses Biochemistry 38 1999 12959 12968
-
(1999)
Biochemistry
, vol.38
, pp. 12959-12968
-
-
Kuschert, G.S.1
Coulin, F.2
Power, C.A.3
Proudfoot, A.E.4
Hubbard, R.E.5
Hoogewerf, A.J.6
-
32
-
-
0030810177
-
Glycosaminoglycans mediate cell surface oligomerization of chemokines
-
A.J. Hoogewerf, G.S. Kuschert, A.E. Proudfoot, F. Borlat, I. Clark-Lewis, and C.A. Power Glycosaminoglycans mediate cell surface oligomerization of chemokines Biochemistry 36 1997 13570 13578
-
(1997)
Biochemistry
, vol.36
, pp. 13570-13578
-
-
Hoogewerf, A.J.1
Kuschert, G.S.2
Proudfoot, A.E.3
Borlat, F.4
Clark-Lewis, I.5
Power, C.A.6
-
33
-
-
0021751840
-
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
-
A.G. Dalgleish, P.C. Beverley, P.R. Clapham, D.H. Crawford, M.F. Greaves, and R.A. Weiss The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus Nature 312 1984 763 767
-
(1984)
Nature
, vol.312
, pp. 763-767
-
-
Dalgleish, A.G.1
Beverley, P.C.2
Clapham, P.R.3
Crawford, D.H.4
Greaves, M.F.5
Weiss, R.A.6
-
34
-
-
0021720872
-
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
-
D. Klatzmann, E. Champagne, S. Chamaret, J. Gruest, D. Guetard, and T. Hercend T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV Nature 312 1984 767 768
-
(1984)
Nature
, vol.312
, pp. 767-768
-
-
Klatzmann, D.1
Champagne, E.2
Chamaret, S.3
Gruest, J.4
Guetard, D.5
Hercend, T.6
-
35
-
-
0023028190
-
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
-
P.J. Maddon, A.G. Dalgleish, J.S. McDougal, P.R. Clapham, R.A. Weiss, and R. Axel The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain Cell 47 1986 333 348
-
(1986)
Cell
, vol.47
, pp. 333-348
-
-
Maddon, P.J.1
Dalgleish, A.G.2
McDougal, J.S.3
Clapham, P.R.4
Weiss, R.A.5
Axel, R.6
-
36
-
-
0025731030
-
Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by Simian immunodeficiency virus
-
P.R. Clapham, D. Blanc, and R.A. Weiss Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by Simian immunodeficiency virus Virology 181 1991 703 715
-
(1991)
Virology
, vol.181
, pp. 703-715
-
-
Clapham, P.R.1
Blanc, D.2
Weiss, R.A.3
-
37
-
-
0026654559
-
Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryons
-
T. Dragic, P. Charneau, F. Clavel, and M. Alizon Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryons J Virol 66 1992 4794 4802
-
(1992)
J Virol
, vol.66
, pp. 4794-4802
-
-
Dragic, T.1
Charneau, P.2
Clavel, F.3
Alizon, M.4
-
38
-
-
0029655669
-
The receptor for HIV: Dissection of CD4 and studies on putative accessory factors
-
W. James, R.A. Weiss, and J.H. Simon The receptor for HIV: dissection of CD4 and studies on putative accessory factors Curr Top Microbiol Immunol 205 1996 137 158
-
(1996)
Curr Top Microbiol Immunol
, vol.205
, pp. 137-158
-
-
James, W.1
Weiss, R.A.2
Simon, J.H.3
-
39
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
E.A. Berger, P.M. Murphy, and J.M. Farber Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease Ann Rev Immunol 17 1999 657 700
-
(1999)
Ann Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
40
-
-
0032577581
-
Chemokine receptors: Keys to AIDS pathogenesis?
-
D.R. Littman Chemokine receptors: keys to AIDS pathogenesis? Cell 93 1998 677 680
-
(1998)
Cell
, vol.93
, pp. 677-680
-
-
Littman, D.R.1
-
41
-
-
0028168943
-
Changing virus-host interactions in the course of HIV-1 infection
-
F. Miedema, L. Meyaard, M. Koot, M.R. Klein, M.T. Roos, and M. Groenink Changing virus-host interactions in the course of HIV-1 infection Immunol Rev 140 1994 35 72
-
(1994)
Immunol Rev
, vol.140
, pp. 35-72
-
-
Miedema, F.1
Meyaard, L.2
Koot, M.3
Klein, M.R.4
Roos, M.T.5
Groenink, M.6
-
42
-
-
0029821869
-
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains
-
J.F. Berson, D. Long, B.J. Doranz, J. Rucker, F.R. Jirik, and R.W. Doms A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains J Virol 70 1996 6288 6295
-
(1996)
J Virol
, vol.70
, pp. 6288-6295
-
-
Berson, J.F.1
Long, D.2
Doranz, B.J.3
Rucker, J.4
Jirik, F.R.5
Doms, R.W.6
-
43
-
-
0029890173
-
Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES
-
C. Combadiere, S.K. Ahuja, H.L. Tiffany, and P.M. Murphy Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES J Leukocyte Biol 60 1996 147 152
-
(1996)
J Leukocyte Biol
, vol.60
, pp. 147-152
-
-
Combadiere, C.1
Ahuja, S.K.2
Tiffany, H.L.3
Murphy, P.M.4
-
44
-
-
0029986131
-
Molecular cloning and functional expression of a new human CC-chemokine receptor gene
-
M. Samson, O. Labbe, C. Mollereau, G. Vassart, and M. Parmentier Molecular cloning and functional expression of a new human CC-chemokine receptor gene Biochemistry 35 1996 3362 3367
-
(1996)
Biochemistry
, vol.35
, pp. 3362-3367
-
-
Samson, M.1
Labbe, O.2
Mollereau, C.3
Vassart, G.4
Parmentier, M.5
-
45
-
-
0005014748
-
The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
H. Choe, M. Farzan, Y. Sun, N. Sullivan, B. Rollins, and P.D. Ponath The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates Cell 85 1996 1135 1148
-
(1996)
Cell
, vol.85
, pp. 1135-1148
-
-
Choe, H.1
Farzan, M.2
Sun, Y.3
Sullivan, N.4
Rollins, B.5
Ponath, P.D.6
-
46
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
C.C. Bleul, M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, and J. Sodroski The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry Nature 382 1996 829 833
-
(1996)
Nature
, vol.382
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
Parolin, C.4
Clark-Lewis, I.5
Sodroski, J.6
-
47
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
E. Oberlin, A. Amara, F. Bachelerie, C. Bessia, J.L. Virelizier, and F. Arenzana-Seisdedos The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1 Nature 382 1996 833 835
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.L.5
Arenzana-Seisdedos, F.6
-
48
-
-
0032529071
-
HIV gp120: Double lock strategy foils host defences
-
Q.J. Sattentau HIV gp120: double lock strategy foils host defences Structure 6 1998 945 949
-
(1998)
Structure
, vol.6
, pp. 945-949
-
-
Sattentau, Q.J.1
-
49
-
-
0034598905
-
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
-
T.B. Geijtenbeek, D.S. Kwon, R. Torensma, S.J. van Vliet, G.C. van Duijnhoven, and J. Middel DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells Cell 100 2000 587 597
-
(2000)
Cell
, vol.100
, pp. 587-597
-
-
Geijtenbeek, T.B.1
Kwon, D.S.2
Torensma, R.3
Van Vliet, S.J.4
Van Duijnhoven, G.C.5
Middel, J.6
-
50
-
-
0035889149
-
HIV gp120 receptors on human dendritic cells
-
S.G. Turville, J. Arthos, K.M. Donald, G. Lynch, H. Naif, and G. Clark HIV gp120 receptors on human dendritic cells Blood 98 2001 2482 2488
-
(2001)
Blood
, vol.98
, pp. 2482-2488
-
-
Turville, S.G.1
Arthos, J.2
Donald, K.M.3
Lynch, G.4
Naif, H.5
Clark, G.6
-
51
-
-
16144365317
-
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
-
A. Trkola, T. Dragic, J. Arthos, J.M. Binley, W.C. Olson, and G.P. Allaway CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5 Nature 384 1996 184 187
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
Dragic, T.2
Arthos, J.3
Binley, J.M.4
Olson, W.C.5
Allaway, G.P.6
-
52
-
-
16144365650
-
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
-
L. Wu, N.P. Gerard, R. Wyatt, H. Choe, C. Parolin, and N. Ruffing CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5 Nature 384 1996 179 183
-
(1996)
Nature
, vol.384
, pp. 179-183
-
-
Wu, L.1
Gerard, N.P.2
Wyatt, R.3
Choe, H.4
Parolin, C.5
Ruffing, N.6
-
53
-
-
0032990223
-
Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
-
T.L. Hoffman, C.C. LaBranche, W. Zhang, G. Canziani, J. Robinson, and I. Chaiken Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein Proc Natl Acad Sci USA 96 1999 6359 6364
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6359-6364
-
-
Hoffman, T.L.1
Labranche, C.C.2
Zhang, W.3
Canziani, G.4
Robinson, J.5
Chaiken, I.6
-
54
-
-
0029955497
-
The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection
-
F. Cocchi, A.L. DeVico, A. Garzino-Demo, A. Cara, R.C. Gallo, and P. Lusso The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection Nat Med 2 1996 1244 1247
-
(1996)
Nat Med
, vol.2
, pp. 1244-1247
-
-
Cocchi, F.1
Devico, A.L.2
Garzino-Demo, A.3
Cara, A.4
Gallo, R.C.5
Lusso, P.6
-
55
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
W. Weissenhorn, A. Dessen, S.C. Harrison, J.J. Skehel, and D.C. Wiley Atomic structure of the ectodomain from HIV-1 gp41 Nature 387 1997 426 430
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
Skehel, J.J.4
Wiley, D.C.5
-
56
-
-
0037474328
-
Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion
-
R. Barbouche, R. Miquelis, I.M. Jones, and E. Fenouillet Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion J Biol Chem 278 2003 3131 3136
-
(2003)
J Biol Chem
, vol.278
, pp. 3131-3136
-
-
Barbouche, R.1
Miquelis, R.2
Jones, I.M.3
Fenouillet, E.4
-
57
-
-
0034715519
-
Beyond receptor expression: The influence of receptor conformation, density, and affinity in HIV-1 infection
-
R.W. Doms Beyond receptor expression: the influence of receptor conformation, density, and affinity in HIV-1 infection Virology 276 2000 229 237
-
(2000)
Virology
, vol.276
, pp. 229-237
-
-
Doms, R.W.1
-
59
-
-
0032837825
-
Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: Two distinct mechanisms of HIV-1 dual tropism
-
Y. Yi, S.N. Isaacs, D.A. Williams, I. Frank, D. Schols, and E. De Clercq Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism J Virol 73 1999 7117 7125
-
(1999)
J Virol
, vol.73
, pp. 7117-7125
-
-
Yi, Y.1
Isaacs, S.N.2
Williams, D.A.3
Frank, I.4
Schols, D.5
De Clercq, E.6
-
60
-
-
0031783562
-
Chemokine receptors and their crucial role in human immunodeficiency virus infection: Major breakthroughs in HIV research
-
T.B. Kristiansen, T.B. Knudsen, and J. Eugen-Olsen Chemokine receptors and their crucial role in human immunodeficiency virus infection: major breakthroughs in HIV research Scand J Immunol 48 1998 339 346
-
(1998)
Scand J Immunol
, vol.48
, pp. 339-346
-
-
Kristiansen, T.B.1
Knudsen, T.B.2
Eugen-Olsen, J.3
-
61
-
-
0034817270
-
Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists
-
E. De Clercq, and D. Schols Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists Antiviral Chem Chemother 12 2001 19 31
-
(2001)
Antiviral Chem Chemother
, vol.12
, pp. 19-31
-
-
De Clercq, E.1
Schols, D.2
-
62
-
-
0036633807
-
Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence
-
A. Jekle, B. Schramm, P. Jayakumar, V. Trautner, D. Schols, and E. De Clercq Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence J Virol 76 2002 6966 6973
-
(2002)
J Virol
, vol.76
, pp. 6966-6973
-
-
Jekle, A.1
Schramm, B.2
Jayakumar, P.3
Trautner, V.4
Schols, D.5
De Clercq, E.6
-
63
-
-
0037695061
-
In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells
-
A. Jekle, O.T. Keppler, E. De Clercq, D. Schols, M. Weinstein, and M.A. Goldsmith In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells J Virol 77 2003 5846 5854
-
(2003)
J Virol
, vol.77
, pp. 5846-5854
-
-
Jekle, A.1
Keppler, O.T.2
De Clercq, E.3
Schols, D.4
Weinstein, M.5
Goldsmith, M.A.6
-
65
-
-
0030670330
-
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression
-
G. Scarlatti, E. Tresoldi, A. Bjorndal, R. Fredriksson, C. Colognesi, and H.K. Deng In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression Nat Med 3 1997 1259 1265
-
(1997)
Nat Med
, vol.3
, pp. 1259-1265
-
-
Scarlatti, G.1
Tresoldi, E.2
Bjorndal, A.3
Fredriksson, R.4
Colognesi, C.5
Deng, H.K.6
-
66
-
-
0030070991
-
Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
-
J.W. Mellors, C.R. Rinaldo Jr., P. Gupta, R.M. White, J.A. Todd, and L.A. Kingsley Prognosis in HIV-1 infection predicted by the quantity of virus in plasma Science 272 1996 1167 1170
-
(1996)
Science
, vol.272
, pp. 1167-1170
-
-
Mellors, J.W.1
Rinaldo Jr., C.R.2
Gupta, P.3
White, R.M.4
Todd, J.A.5
Kingsley, L.A.6
-
67
-
-
0029064202
-
Virologic and immunologic characterization of symptomatic and asymptomatic primary HIV-1 infection
-
D.R. Henrard, E. Daar, H. Farzadegan, S.J. Clark, J. Phillips, and G.M. Shaw Virologic and immunologic characterization of symptomatic and asymptomatic primary HIV-1 infection J Acquir Immune Defic Syndr Hum Retrovirol 9 1995 305 310
-
(1995)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.9
, pp. 305-310
-
-
Henrard, D.R.1
Daar, E.2
Farzadegan, H.3
Clark, S.J.4
Phillips, J.5
Shaw, G.M.6
-
68
-
-
0028874048
-
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
-
D.D. Ho, A.U. Neumann, A.S. Perelson, W. Chen, J.M. Leonard, and M. Markowitz Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection Nature 373 1995 123 126
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
Neumann, A.U.2
Perelson, A.S.3
Chen, W.4
Leonard, J.M.5
Markowitz, M.6
-
69
-
-
0031575431
-
Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals
-
R.I. Connor, K.E. Sheridan, D. Ceradini, S. Choe, and N.R. Landau Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals J Exp Med 185 1997 621 628
-
(1997)
J Exp Med
, vol.185
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
70
-
-
0033059948
-
Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4
-
J.A. Este, C. Cabrera, J. Blanco, A. Gutierrez, G. Bridger, and G. Henson Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4 J Virol 73 1999 5577 5585
-
(1999)
J Virol
, vol.73
, pp. 5577-5585
-
-
Este, J.A.1
Cabrera, C.2
Blanco, J.3
Gutierrez, A.4
Bridger, G.5
Henson, G.6
-
71
-
-
0032728566
-
Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo
-
S. Glushakova, Y. Yi, J.C. Grivel, A. Singh, D. Schols, and E. De Clercq Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo J Clin Invest 104 1999 R7 R11
-
(1999)
J Clin Invest
, vol.104
-
-
Glushakova, S.1
Yi, Y.2
Grivel, J.C.3
Singh, A.4
Schols, D.5
De Clercq, E.6
-
72
-
-
0026600926
-
Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
-
H. Schuitemaker, M. Koot, N.A. Kootstra, M.W. Dercksen, R.E. de Goede, and R.P. van Steenwijk Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population J Virol 66 1992 1354 1360
-
(1992)
J Virol
, vol.66
, pp. 1354-1360
-
-
Schuitemaker, H.1
Koot, M.2
Kootstra, N.A.3
Dercksen, M.W.4
De Goede, R.E.5
Van Steenwijk, R.P.6
-
73
-
-
0026606727
-
Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
-
R.A. Fouchier, M. Groenink, N.A. Kootstra, M. Tersmette, H.G. Huisman, and F. Miedema Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule J Virol 66 1992 3183 3187
-
(1992)
J Virol
, vol.66
, pp. 3183-3187
-
-
Fouchier, R.A.1
Groenink, M.2
Kootstra, N.A.3
Tersmette, M.4
Huisman, H.G.5
Miedema, F.6
-
74
-
-
0028950499
-
Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR
-
R.A. Fouchier, M. Brouwer, S.M. Broersen, and H. Schuitemaker Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR J Clin Microbiol 33 1995 906 911
-
(1995)
J Clin Microbiol
, vol.33
, pp. 906-911
-
-
Fouchier, R.A.1
Brouwer, M.2
Broersen, S.M.3
Schuitemaker, H.4
-
75
-
-
0038637409
-
Predicting HIV-1 coreceptor usage with sequence analysis
-
M.A. Jensen, and A.B. 't Wout Predicting HIV-1 coreceptor usage with sequence analysis AIDS Rev 5 2003 104 112
-
(2003)
AIDS Rev
, vol.5
, pp. 104-112
-
-
Jensen, M.A.1
Wout A B, '.T.2
-
76
-
-
1842415431
-
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
-
A. Bjorndal, H. Deng, M. Jansson, J.R. Fiore, C. Colognesi, and A. Karlsson Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype J Virol 71 1997 7478 7487
-
(1997)
J Virol
, vol.71
, pp. 7478-7487
-
-
Bjorndal, A.1
Deng, H.2
Jansson, M.3
Fiore, J.R.4
Colognesi, C.5
Karlsson, A.6
-
77
-
-
0037223748
-
Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins
-
G. Lin, F. Baribaud, J. Romano, R.W. Doms, and J.A. Hoxie Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins J Virol 77 2003 931 942
-
(2003)
J Virol
, vol.77
, pp. 931-942
-
-
Lin, G.1
Baribaud, F.2
Romano, J.3
Doms, R.W.4
Hoxie, J.A.5
-
78
-
-
0034466833
-
Evolution of the human immunodeficiency virus type 1 envelope during infection reveals molecular corollaries of specificity for coreceptor utilization and AIDS pathogenesis
-
Q.X. Hu, A.P. Barry, Z.X. Wang, S.M. Connolly, S.C. Peiper, and M.L. Greenberg Evolution of the human immunodeficiency virus type 1 envelope during infection reveals molecular corollaries of specificity for coreceptor utilization and AIDS pathogenesis J Virol 74 2000 11858 11872
-
(2000)
J Virol
, vol.74
, pp. 11858-11872
-
-
Hu, Q.X.1
Barry, A.P.2
Wang, Z.X.3
Connolly, S.M.4
Peiper, S.C.5
Greenberg, M.L.6
-
79
-
-
0030745286
-
HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
-
A. Amara, S.L. Gall, O. Schwartz, J. Salamero, M. Montes, and P. Loetscher HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication J Exp Med 186 1997 139 146
-
(1997)
J Exp Med
, vol.186
, pp. 139-146
-
-
Amara, A.1
Gall, S.L.2
Schwartz, O.3
Salamero, J.4
Montes, M.5
Loetscher, P.6
-
80
-
-
0032550337
-
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
-
M. Mack, B. Luckow, P.J. Nelson, J. Cihak, G. Simmons, and P.R. Clapham Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity J Exp Med 187 1998 1215 1224
-
(1998)
J Exp Med
, vol.187
, pp. 1215-1224
-
-
MacK, M.1
Luckow, B.2
Nelson, P.J.3
Cihak, J.4
Simmons, G.5
Clapham, P.R.6
-
81
-
-
0345003718
-
Opposite effects of SDF-1 on human immunodeficiency virus type 1 replication
-
V. Marechal, F. Arenzana-Seisdedos, J.M. Heard, and O. Schwartz Opposite effects of SDF-1 on human immunodeficiency virus type 1 replication J Virol 73 1999 3608 3615
-
(1999)
J Virol
, vol.73
, pp. 3608-3615
-
-
Marechal, V.1
Arenzana-Seisdedos, F.2
Heard, J.M.3
Schwartz, O.4
-
83
-
-
12644274812
-
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure
-
W.A. Paxton, S.R. Martin, D. Tse, T.R. O'Brien, J. Skurnick, and N.L. VanDevanter Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure Nat Med 2 1996 412 417
-
(1996)
Nat Med
, vol.2
, pp. 412-417
-
-
Paxton, W.A.1
Martin, S.R.2
Tse, D.3
O'Brien, T.R.4
Skurnick, J.5
Vandevanter, N.L.6
-
84
-
-
0032889517
-
Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
-
C.J. Gordon, M.A. Muesing, A.E. Proudfoot, C.A. Power, J.P. Moore, and A. Trkola Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion J Virol 73 1999 684 694
-
(1999)
J Virol
, vol.73
, pp. 684-694
-
-
Gordon, C.J.1
Muesing, M.A.2
Proudfoot, A.E.3
Power, C.A.4
Moore, J.P.5
Trkola, A.6
-
85
-
-
0032038626
-
Dichotomous effects of beta-chemokines on HIV replication in monocytes and monocyte-derived macrophages
-
M.D. Kelly, H.M. Naif, S.L. Adams, A.L. Cunningham, and A.R. Lloyd Dichotomous effects of beta-chemokines on HIV replication in monocytes and monocyte-derived macrophages J Immunol 160 1998 3091 3095
-
(1998)
J Immunol
, vol.160
, pp. 3091-3095
-
-
Kelly, M.D.1
Naif, H.M.2
Adams, S.L.3
Cunningham, A.L.4
Lloyd, A.R.5
-
86
-
-
0034881257
-
Mechanisms involved in stimulation of human immunodeficiency virus type 1 replication by aminooxypentane RANTES
-
A.J. Marozsan, V.S. Torre, M. Johnson, S.C. Ball, J.V. Cross, and D.J. Templeton Mechanisms involved in stimulation of human immunodeficiency virus type 1 replication by aminooxypentane RANTES J Virol 75 2001 8624 8638
-
(2001)
J Virol
, vol.75
, pp. 8624-8638
-
-
Marozsan, A.J.1
Torre, V.S.2
Johnson, M.3
Ball, S.C.4
Cross, J.V.5
Templeton, D.J.6
-
87
-
-
0032924183
-
Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants
-
D.E. Mosier, G.R. Picchio, R.J. Gulizia, R. Sabbe, P. Poignard, and L. Picard Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants J Virol 73 1999 3544 3550
-
(1999)
J Virol
, vol.73
, pp. 3544-3550
-
-
Mosier, D.E.1
Picchio, G.R.2
Gulizia, R.J.3
Sabbe, R.4
Poignard, P.5
Picard, L.6
-
88
-
-
0032768967
-
The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity
-
A. Trkola, C. Gordon, J. Matthews, E. Maxwell, T. Ketas, and L. Czaplewski The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity J Virol 73 1999 6370 6379
-
(1999)
J Virol
, vol.73
, pp. 6370-6379
-
-
Trkola, A.1
Gordon, C.2
Matthews, J.3
Maxwell, E.4
Ketas, T.5
Czaplewski, L.6
-
89
-
-
77956722892
-
Dual effect of CCR5 Δ32 gene deletion in HIV-1-infected patients. Copenhagen AIDS Study Group
-
P. Garred, J. Eugen-Olsen, A.K. Iversen, T.L. Benfield, A. Svejgaard, and B. Hofmann Dual effect of CCR5 Δ32 gene deletion in HIV-1-infected patients. Copenhagen AIDS Study Group Lancet 349 1997 1884
-
(1997)
Lancet
, vol.349
, pp. 1884
-
-
Garred, P.1
Eugen-Olsen, J.2
Iversen, A.K.3
Benfield, T.L.4
Svejgaard, A.5
Hofmann, B.6
-
90
-
-
17544384752
-
Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 Δ32
-
N.L. Michael, J.A. Nelson, V.N. KewalRamani, G. Chang, S.J. O'Brien, and J.R. Mascola Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 Δ32 J Virol 72 1998 6040 6047
-
(1998)
J Virol
, vol.72
, pp. 6040-6047
-
-
Michael, N.L.1
Nelson, J.A.2
Kewalramani, V.N.3
Chang, G.4
O'Brien, S.J.5
Mascola, J.R.6
-
91
-
-
20044377204
-
The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility
-
E. Gonzalez, H. Kulkarni, H. Bolivar, A. Mangano, R. Sanchez, and G. Catano The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility Science 307 2005 1434 1440
-
(2005)
Science
, vol.307
, pp. 1434-1440
-
-
Gonzalez, E.1
Kulkarni, H.2
Bolivar, H.3
Mangano, A.4
Sanchez, R.5
Catano, G.6
-
92
-
-
0032482926
-
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
-
Q. Ma, D. Jones, P.R. Borghesani, R.A. Segal, T. Nagasawa, and T. Kishimoto Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice Proc Natl Acad Sci USA 95 1998 9448 9453
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9448-9453
-
-
Ma, Q.1
Jones, D.2
Borghesani, P.R.3
Segal, R.A.4
Nagasawa, T.5
Kishimoto, T.6
-
93
-
-
0029758113
-
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
-
T. Nagasawa, S. Hirota, K. Tachibana, N. Takakura, S. Nishikawa, and Y. Kitamura Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1 Nature 382 1996 635 638
-
(1996)
Nature
, vol.382
, pp. 635-638
-
-
Nagasawa, T.1
Hirota, S.2
Tachibana, K.3
Takakura, N.4
Nishikawa, S.5
Kitamura, Y.6
-
94
-
-
0032507962
-
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
-
Y.R. Zou, A.H. Kottmann, M. Kuroda, I. Taniuchi, and D.R. Littman Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development Nature 393 1998 595 599
-
(1998)
Nature
, vol.393
, pp. 595-599
-
-
Zou, Y.R.1
Kottmann, A.H.2
Kuroda, M.3
Taniuchi, I.4
Littman, D.R.5
-
95
-
-
0032745543
-
The LD78β isoform of MIP-1α is the most potent CCR5 agonist and HIV-1-inhibiting chemokine
-
P. Menten, S. Struyf, E. Schutyser, A. Wuyts, E. De Clercq, and D. Schols The LD78β isoform of MIP-1α is the most potent CCR5 agonist and HIV-1-inhibiting chemokine J Clin Invest 104 1999 R1 R5
-
(1999)
J Clin Invest
, vol.104
-
-
Menten, P.1
Struyf, S.2
Schutyser, E.3
Wuyts, A.4
De Clercq, E.5
Schols, D.6
-
96
-
-
0034744508
-
The LD78β isoform of MIP-1α is the most potent CC-chemokine in inhibiting CCR5-dependent human immunodeficiency virus type 1 replication in human macrophages
-
S. Aquaro, P. Menten, S. Struyf, P. Proost, J. Van Damme, and E. De Clercq The LD78β isoform of MIP-1α is the most potent CC-chemokine in inhibiting CCR5-dependent human immunodeficiency virus type 1 replication in human macrophages J Virol 75 2001 4402 4406
-
(2001)
J Virol
, vol.75
, pp. 4402-4406
-
-
Aquaro, S.1
Menten, P.2
Struyf, S.3
Proost, P.4
Van Damme, J.5
De Clercq, E.6
-
97
-
-
0038560496
-
CD26, let it cut or cut it down
-
I. De Meester, S. Korom, J. Van Damme, and S. Scharpe CD26, let it cut or cut it down Immunol Today 20 1999 367 375
-
(1999)
Immunol Today
, vol.20
, pp. 367-375
-
-
De Meester, I.1
Korom, S.2
Van Damme, J.3
Scharpe, S.4
-
98
-
-
17044448314
-
CD26-processed RANTES(3-68), but not intact RANTES, has potent anti-HIV-1 activity
-
D. Schols, P. Proost, S. Struyf, A. Wuyts, M.I. De, and S. Scharpe CD26-processed RANTES(3-68), but not intact RANTES, has potent anti-HIV-1 activity Antiviral Res 39 1998 175 187
-
(1998)
Antiviral Res
, vol.39
, pp. 175-187
-
-
Schols, D.1
Proost, P.2
Struyf, S.3
Wuyts, A.4
De, M.I.5
Scharpe, S.6
-
99
-
-
0032571360
-
Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase. IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection
-
P. Proost, M.I. De, D. Schols, S. Struyf, A.M. Lambeir, and A. Wuyts Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase. IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection J Biol Chem 273 1998 7222 7227
-
(1998)
J Biol Chem
, vol.273
, pp. 7222-7227
-
-
Proost, P.1
De, M.I.2
Schols, D.3
Struyf, S.4
Lambeir, A.M.5
Wuyts, A.6
-
100
-
-
16044370301
-
HIV blocked by chemokine antagonist
-
F. Arenzana-Seisdedos, J.L. Virelizier, D. Rousset, I. Clark-Lewis, P. Loetscher, and B. Moser HIV blocked by chemokine antagonist Nature 383 1996 400
-
(1996)
Nature
, vol.383
, pp. 400
-
-
Arenzana-Seisdedos, F.1
Virelizier, J.L.2
Rousset, D.3
Clark-Lewis, I.4
Loetscher, P.5
Moser, B.6
-
101
-
-
0030951442
-
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
-
G. Simmons, P.R. Clapham, L. Picard, R.E. Offord, M.M. Rosenkilde, and T.W. Schwartz Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist Science 276 1997 276 279
-
(1997)
Science
, vol.276
, pp. 276-279
-
-
Simmons, G.1
Clapham, P.R.2
Picard, L.3
Offord, R.E.4
Rosenkilde, M.M.5
Schwartz, T.W.6
-
102
-
-
0030022954
-
Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist
-
A.E. Proudfoot, C.A. Power, A.J. Hoogewerf, M.O. Montjovent, F. Borlat, and R.E. Offord Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist J Biol Chem 271 1996 2599 2603
-
(1996)
J Biol Chem
, vol.271
, pp. 2599-2603
-
-
Proudfoot, A.E.1
Power, C.A.2
Hoogewerf, A.J.3
Montjovent, M.O.4
Borlat, F.5
Offord, R.E.6
-
103
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
M.M. Lederman, R.S. Veazey, R. Offord, D.E. Mosier, J. Dufour, and M. Mefford Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5 Science 306 2004 485 487
-
(2004)
Science
, vol.306
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
Mosier, D.E.4
Dufour, J.5
Mefford, M.6
-
104
-
-
0034671725
-
Aminooxypentane addition to the chemokine macrophage inflammatory protein-1alpha P increases receptor affinities and HIV inhibition
-
J.R. Townson, G.J. Graham, N.R. Landau, B. Rasala, and R.J. Nibbs Aminooxypentane addition to the chemokine macrophage inflammatory protein-1alpha P increases receptor affinities and HIV inhibition J Biol Chem 275 2000 39254 39261
-
(2000)
J Biol Chem
, vol.275
, pp. 39254-39261
-
-
Townson, J.R.1
Graham, G.J.2
Landau, N.R.3
Rasala, B.4
Nibbs, R.J.5
-
105
-
-
0032990719
-
Enhanced inhibition of human immunodeficiency virus type 1 by Met-stromal-derived factor 1beta correlates with down-modulation of CXCR4
-
O.O. Yang, S.L. Swanberg, Z. Lu, M. Dziejman, J. McCoy, and A.D. Luster Enhanced inhibition of human immunodeficiency virus type 1 by Met-stromal-derived factor 1beta correlates with down-modulation of CXCR4 J Virol 73 1999 4582 4589
-
(1999)
J Virol
, vol.73
, pp. 4582-4589
-
-
Yang, O.O.1
Swanberg, S.L.2
Lu, Z.3
Dziejman, M.4
McCoy, J.5
Luster, A.D.6
-
106
-
-
0026683326
-
Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event
-
E. De Clercq, N. Yamamoto, R. Pauwels, M. Baba, D. Schols, and H. Nakashima Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event Proc Natl Acad Sci USA 89 1992 5286 5290
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5286-5290
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
Baba, M.4
Schols, D.5
Nakashima, H.6
-
107
-
-
0038681342
-
The bicyclam AMD3100 story
-
E. De Clercq The bicyclam AMD3100 story Nat Rev Drug Discov 2 2003 581 587
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 581-587
-
-
De Clercq, E.1
-
108
-
-
0028209166
-
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100
-
E. De Clercq, N. Yamamoto, R. Pauwels, J. Balzarini, M. Witvrouw, and K. De Vreese Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100 Antimicrob Agents Chemother 38 1994 668 674
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 668-674
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
Balzarini, J.4
Witvrouw, M.5
De Vreese, K.6
-
109
-
-
0029067663
-
Synthesis and structure-activity relationships of phenylenebis(methylene) -linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker
-
G.J. Bridger, R.T. Skerlj, D. Thornton, S. Padmanabhan, S.A. Martellucci, and G.W. Henson Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker J Med Chem 38 1995 366 378
-
(1995)
J Med Chem
, vol.38
, pp. 366-378
-
-
Bridger, G.J.1
Skerlj, R.T.2
Thornton, D.3
Padmanabhan, S.4
Martellucci, S.A.5
Henson, G.W.6
-
110
-
-
0029086827
-
Quantitative structural activity relationship study of bis-tetraazacyclic compounds. a novel series of HIV-1 and HIV-2 inhibitors
-
H.C. Joao, K. De Vreese, R. Pauwels, E. De Clercq, G.W. Henson, and G.J. Bridger Quantitative structural activity relationship study of bis-tetraazacyclic compounds. A novel series of HIV-1 and HIV-2 inhibitors J Med Chem 38 1995 3865 3873
-
(1995)
J Med Chem
, vol.38
, pp. 3865-3873
-
-
Joao, H.C.1
De Vreese, K.2
Pauwels, R.3
De Clercq, E.4
Henson, G.W.5
Bridger, G.J.6
-
111
-
-
0003973947
-
The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication
-
K. De Vreese, V. Kofler-Mongold, C. Leutgeb, V. Weber, K. Vermeire, and S. Schacht The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication J Virol 70 1996 689 696
-
(1996)
J Virol
, vol.70
, pp. 689-696
-
-
De Vreese, K.1
Kofler-Mongold, V.2
Leutgeb, C.3
Weber, V.4
Vermeire, K.5
Schacht, S.6
-
112
-
-
0030781371
-
Sensitivity of human immunodeficiency virus to bicyclam derivatives is influenced by the three-dimensional structure of gp120
-
K. De Vreese, N.I. Van, K. Vermeire, J. Anne, and E. De Clercq Sensitivity of human immunodeficiency virus to bicyclam derivatives is influenced by the three-dimensional structure of gp120 Antimicrob Agents Chemother 41 1997 2616 2620
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 2616-2620
-
-
De Vreese, K.1
Van, N.I.2
Vermeire, K.3
Anne, J.4
De Clercq, E.5
-
113
-
-
0029916728
-
Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1
-
J.A. Este, K. De Vreese, M. Witvrouw, J.C. Schmit, A.M. VanDamme, and J. Anne Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1 Antiviral Res 29 1996 297 307
-
(1996)
Antiviral Res
, vol.29
, pp. 297-307
-
-
Este, J.A.1
De Vreese, K.2
Witvrouw, M.3
Schmit, J.C.4
Vandamme, A.M.5
Anne, J.6
-
114
-
-
0030835663
-
Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4
-
D. Schols, J.A. Este, G. Henson, and E. De Clercq Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4 Antiviral Res 35 1997 147 156
-
(1997)
Antiviral Res
, vol.35
, pp. 147-156
-
-
Schols, D.1
Este, J.A.2
Henson, G.3
De Clercq, E.4
-
115
-
-
0030830661
-
Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
-
D. Schols, S. Struyf, J. Van Damme, J.A. Este, G. Henson, and E. De Clercq Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4 J Exp Med 186 1997 1383 1388
-
(1997)
J Exp Med
, vol.186
, pp. 1383-1388
-
-
Schols, D.1
Struyf, S.2
Van Damme, J.3
Este, J.A.4
Henson, G.5
De Clercq, E.6
-
116
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
G.A. Donzella, D. Schols, S.W. Lin, J.A. Este, K.A. Nagashima, and P.J. Maddon AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor Nat Med 4 1998 72 77
-
(1998)
Nat Med
, vol.4
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
Este, J.A.4
Nagashima, K.A.5
Maddon, P.J.6
-
117
-
-
0033989712
-
Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease
-
B. Schramm, M.L. Penn, R.F. Speck, S.Y. Chan, E. De Clercq, and D. Schols Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease J Virol 74 2000 184 192
-
(2000)
J Virol
, vol.74
, pp. 184-192
-
-
Schramm, B.1
Penn, M.L.2
Speck, R.F.3
Chan, S.Y.4
De Clercq, E.5
Schols, D.6
-
118
-
-
0037063329
-
Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4
-
S. Hatse, K. Princen, G. Bridger, E. De Clercq, and D. Schols Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4 FEBS Lett 527 2002 255 262
-
(2002)
FEBS Lett
, vol.527
, pp. 255-262
-
-
Hatse, S.1
Princen, K.2
Bridger, G.3
De Clercq, E.4
Schols, D.5
-
119
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
-
C.W. Hendrix, C. Flexner, R.T. MacFarland, C. Giandomenico, E.J. Fuchs, and E. Redpath Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers Antimicrob Agents Chemother 44 2000 1667 1673
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
Giandomenico, C.4
Fuchs, E.J.5
Redpath, E.6
-
120
-
-
4644227515
-
Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection
-
C.W. Hendrix, A.C. Collier, M.M. Lederman, D. Schols, R.B. Pollard, and S. Brown Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection J Acquir Immune Defic Syndr 37 2004 1253 1262
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
, pp. 1253-1262
-
-
Hendrix, C.W.1
Collier, A.C.2
Lederman, M.M.3
Schols, D.4
Pollard, R.B.5
Brown, S.6
-
121
-
-
0030780377
-
A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
-
T. Murakami, T. Nakajima, Y. Koyanagi, K. Tachibana, N. Fujii, and H. Tamamura A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection J Exp Med 186 1997 1389 1393
-
(1997)
J Exp Med
, vol.186
, pp. 1389-1393
-
-
Murakami, T.1
Nakajima, T.2
Koyanagi, Y.3
Tachibana, K.4
Fujii, N.5
Tamamura, H.6
-
122
-
-
0032954383
-
T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure
-
R. Arakaki, H. Tamamura, M. Premanathan, K. Kanbara, S. Ramanan, and K. Mochizuki T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure J Virol 73 1999 1719 1723
-
(1999)
J Virol
, vol.73
, pp. 1719-1723
-
-
Arakaki, R.1
Tamamura, H.2
Premanathan, M.3
Kanbara, K.4
Ramanan, S.5
Mochizuki, K.6
-
123
-
-
0032583575
-
A low-molecular-weight inhibitor against the chemokine receptor CXCR4: A strong anti-HIV peptide T140
-
H. Tamamura, Y. Xu, T. Hattori, X. Zhang, R. Arakaki, and K. Kanbara A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140 Biochem Biophys Res Com 253 1998 877 882
-
(1998)
Biochem Biophys Res Com
, vol.253
, pp. 877-882
-
-
Tamamura, H.1
Xu, Y.2
Hattori, T.3
Zhang, X.4
Arakaki, R.5
Kanbara, K.6
-
124
-
-
0030773515
-
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
-
B.J. Doranz, K. Grovit-Ferbas, M.P. Sharron, S.H. Mao, M.B. Goetz, and E.S. Daar A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor J Exp Med 186 1997 1395 1400
-
(1997)
J Exp Med
, vol.186
, pp. 1395-1400
-
-
Doranz, B.J.1
Grovit-Ferbas, K.2
Sharron, M.P.3
Mao, S.H.4
Goetz, M.B.5
Daar, E.S.6
-
125
-
-
0028939016
-
Antiherpetic activities of N-alpha-acetyl-nona-d-arginine amide acetate
-
M. Sumner-Smith, Y. Zheng, Y.P. Zhang, E.M. Twist, and S.C. Climie Antiherpetic activities of N-alpha-acetyl-nona-d-arginine amide acetate Drugs Exp Clin Res 21 1995 1 6
-
(1995)
Drugs Exp Clin Res
, vol.21
, pp. 1-6
-
-
Sumner-Smith, M.1
Zheng, Y.2
Zhang, Y.P.3
Twist, E.M.4
Climie, S.C.5
-
126
-
-
0034915564
-
Safe use of the CXCR4 inhibitor ALX40-4C in humans
-
B.J. Doranz, L.G. Filion, F. Diaz-Mitoma, D.S. Sitar, J. Sahai, and F. Baribaud Safe use of the CXCR4 inhibitor ALX40-4C in humans AIDS Res Hum Retrovir 17 2001 475 486
-
(2001)
AIDS Res Hum Retrovir
, vol.17
, pp. 475-486
-
-
Doranz, B.J.1
Filion, L.G.2
Diaz-Mitoma, F.3
Sitar, D.S.4
Sahai, J.5
Baribaud, F.6
-
127
-
-
0042668582
-
Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1
-
N. Zhou, J. Fang, E. Acheampong, M. Mukhtar, and R.J. Pomerantz Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1 Virology 312 2003 196 203
-
(2003)
Virology
, vol.312
, pp. 196-203
-
-
Zhou, N.1
Fang, J.2
Acheampong, E.3
Mukhtar, M.4
Pomerantz, R.J.5
-
128
-
-
0033971512
-
A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: Inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry
-
D. Daelemans, D. Schols, M. Witvrouw, C. Pannecouque, S. Hatse, and S. van Dooren A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry Mol Pharmacol 57 2000 116 124
-
(2000)
Mol Pharmacol
, vol.57
, pp. 116-124
-
-
Daelemans, D.1
Schols, D.2
Witvrouw, M.3
Pannecouque, C.4
Hatse, S.5
Van Dooren, S.6
-
129
-
-
0030976612
-
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication
-
F. Hamy, E.R. Felder, G. Heizmann, J. Lazdins, F. Aboul-ela, and G. Varani An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication Proc Natl Acad Sci USA 94 1997 3548 3553
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3548-3553
-
-
Hamy, F.1
Felder, E.R.2
Heizmann, G.3
Lazdins, J.4
Aboul-Ela, F.5
Varani, G.6
-
130
-
-
0037388121
-
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity
-
K. Ichiyama, S. Yokoyama-Kumakura, Y. Tanaka, R. Tanaka, K. Hirose, and K. Bannai A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity Proc Natl Acad Sci USA 100 2003 4185 4190
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4185-4190
-
-
Ichiyama, K.1
Yokoyama-Kumakura, S.2
Tanaka, Y.3
Tanaka, R.4
Hirose, K.5
Bannai, K.6
-
131
-
-
0041893844
-
Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist
-
Boston, USA
-
D. Schols, S. Claes, S. Hatse, K. Princen, K. Vermeire, and E. De Clercq Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist Proceedings of the 10th conference on retroviruses and opportunistic infections Boston, USA 2003 [Abstract book, p. 257]
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
-
-
Schols, D.1
Claes, S.2
Hatse, S.3
Princen, K.4
Vermeire, K.5
De Clercq, E.6
-
132
-
-
8644270505
-
Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist
-
K. Princen, S. Hatse, K. Vermeire, S. Aquaro, E. De Clercq, and L.O. Gerlach Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist J Virol 78 2004 12996 13006
-
(2004)
J Virol
, vol.78
, pp. 12996-13006
-
-
Princen, K.1
Hatse, S.2
Vermeire, K.3
Aquaro, S.4
De Clercq, E.5
Gerlach, L.O.6
-
133
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
M. Baba, O. Nishimura, N. Kanzaki, M. Okamoto, H. Sawada, and Y. Iizawa A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity Proc Natl Acad Sci USA 96 1999 5698 5703
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
-
134
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
T. Dragic, A. Trkola, D.A. Thompson, E.G. Cormier, F.A. Kajumo, and E. Maxwell A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5 Proc Natl Acad Sci USA 97 2000 5639 5644
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5639-5644
-
-
Dragic, T.1
Trkola, A.2
Thompson, D.A.3
Cormier, E.G.4
Kajumo, F.A.5
Maxwell, E.6
-
135
-
-
0035940445
-
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
-
J.M. Strizki, S. Xu, N.E. Wagner, L. Wojcik, J. Liu, and Y. Hou SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo Proc Natl Acad Sci USA 98 2001 12718 12723
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12718-12723
-
-
Strizki, J.M.1
Xu, S.2
Wagner, N.E.3
Wojcik, L.4
Liu, J.5
Hou, Y.6
-
136
-
-
0003339453
-
SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1 infected subjects
-
Seattle, USA
-
J. Reynes, R. Rouzier, T. Kanouni, V. Baillat, B. Baroudy, and A. Keung SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1 infected subjects Proceedings of the Ninth conference on retroviruses and opportunistic infections Seattle, USA 2002 [Abstract book, p. 53]
-
(2002)
Proceedings of the Ninth Conference on Retroviruses and Opportunistic Infections
-
-
Reynes, J.1
Rouzier, R.2
Kanouni, T.3
Baillat, V.4
Baroudy, B.5
Keung, A.6
-
137
-
-
2642563856
-
SCH-D: Antiviral activity of CCR5 receptor antagonist
-
San Fransisco, USA
-
D. Schurmann, R. Rouzier, R. Nougarede, J. Reynes, G. Fatkenheuer, and F. Raffi SCH-D: Antiviral activity of CCR5 receptor antagonist Proceedings of the 11th conference on retroviruses and opportunistic infections San Fransisco, USA 2004 [Abstract book, p. 128]
-
(2004)
Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections
-
-
Schurmann, D.1
Rouzier, R.2
Nougarede, R.3
Reynes, J.4
Fatkenheuer, G.5
Raffi, F.6
-
138
-
-
0035860744
-
Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5
-
K. Maeda, K. Yoshimura, S. Shibayama, H. Habashita, H. Tada, and K. Sagawa Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5 J Biol Chem 276 2001 35194 35200
-
(2001)
J Biol Chem
, vol.276
, pp. 35194-35200
-
-
Maeda, K.1
Yoshimura, K.2
Shibayama, S.3
Habashita, H.4
Tada, H.5
Sagawa, K.6
-
139
-
-
21644478914
-
AK602: A novel HIV-specific spirodiketopiperazine CCR5 inhibitor potent against a wide spectrum of R5-HIV
-
Boston, USA
-
K. Maeda, H. Nakata, T. Miyakawa, H. Ogata, Y. Koh, and S. Shibayama AK602: a novel HIV-specific spirodiketopiperazine CCR5 inhibitor potent against a wide spectrum of R5-HIV Proceedings of the 10th conference on retroviruses and opportunistic infections Boston, USA 2003 [Abstract book, p. 61]
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
-
-
Maeda, K.1
Nakata, H.2
Miyakawa, T.3
Ogata, H.4
Koh, Y.5
Shibayama, S.6
-
140
-
-
1842829822
-
The preclinical pharmacokinetics and safety pharmacology of the anti-HIV CCR5 antagonist, UK-427857
-
Boston, USA
-
C. Napier, P. Dorr, R. Gladue, R. Halliday, D. Leishman, and I. Machin The preclinical pharmacokinetics and safety pharmacology of the anti-HIV CCR5 antagonist, UK-427857 Proceedings of the 10th conference on retroviruses and opportunistic infections Boston, USA 2003 [Abstract book, p. 251]
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
-
-
Napier, C.1
Dorr, P.2
Gladue, R.3
Halliday, R.4
Leishman, D.5
MacHin, I.6
-
141
-
-
0035173073
-
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140
-
A. Trkola, T.J. Ketas, K.A. Nagashima, L. Zhao, T. Cilliers, and L. Morris Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140 J Virol 75 2001 579 588
-
(2001)
J Virol
, vol.75
, pp. 579-588
-
-
Trkola, A.1
Ketas, T.J.2
Nagashima, K.A.3
Zhao, L.4
Cilliers, T.5
Morris, L.6
-
142
-
-
3543086670
-
Control of HIV-1 replication in the hu-PBL-SCID mouse model by an anti-CCR5 monoclonal antibody
-
San Francisco, USA
-
M. Franti, L. Ramos, S. Maloveste, D. Geerdes, K.A. Nagashima, and T. Ketas Control of HIV-1 replication in the hu-PBL-SCID mouse model by an anti-CCR5 monoclonal antibody Proceedings of the 11th conference on retroviruses and opportunistic infections San Francisco, USA 2004 [Abstract book, p. 257]
-
(2004)
Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections
-
-
Franti, M.1
Ramos, L.2
Maloveste, S.3
Geerdes, D.4
Nagashima, K.A.5
Ketas, T.6
-
143
-
-
0011309256
-
AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans
-
Seattle, USA
-
D. Schols, S. Claes, E. De Clercq, C. Hendrix, G. Bridger, and G. Calandra AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans Proceedings of the 9th conference on retroviruses and opportunistic infections Seattle, USA 2002 [Abstract book, p. 53]
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
-
-
Schols, D.1
Claes, S.2
De Clercq, E.3
Hendrix, C.4
Bridger, G.5
Calandra, G.6
-
144
-
-
0042896002
-
Potent in vivo anti-R5-HIV effects of AK602, a novel spirodiketopiperazine (SDP)-containing HIV-specific CCR5 inhibitor, in hu-PBMC-NOD-SCID Mice
-
Boston, USA
-
H. Nakata, K. Maeda, Y. Kawano, T. Miyakawa, S. Shibayama, and M. Matsuo Potent in vivo anti-R5-HIV effects of AK602, a novel spirodiketopiperazine (SDP)-containing HIV-specific CCR5 inhibitor, in hu-PBMC-NOD-SCID Mice Proceedings of the 10th conference on retroviruses and opportunistic infections Boston, USA 2003 [Abstract book, p. 258]
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
-
-
Nakata, H.1
Maeda, K.2
Kawano, Y.3
Miyakawa, T.4
Shibayama, S.5
Matsuo, M.6
-
145
-
-
0030604727
-
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
-
B.J. Doranz, J. Rucker, Y. Yi, R.J. Smyth, M. Samson, and S.C. Peiper A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors Cell 85 1996 1149 1158
-
(1996)
Cell
, vol.85
, pp. 1149-1158
-
-
Doranz, B.J.1
Rucker, J.2
Yi, Y.3
Smyth, R.J.4
Samson, M.5
Peiper, S.C.6
-
146
-
-
0032512586
-
Identification of the chemokine receptor TER1/CCR8 expressed in brain-derived cells and T cells as a new coreceptor for HIV-1 infection
-
A. Jinno, N. Shimizu, Y. Soda, Y. Haraguchi, T. Kitamura, and H. Hoshino Identification of the chemokine receptor TER1/CCR8 expressed in brain-derived cells and T cells as a new coreceptor for HIV-1 infection Biochem Biophys Res Commun 243 1998 497 502
-
(1998)
Biochem Biophys Res Commun
, vol.243
, pp. 497-502
-
-
Jinno, A.1
Shimizu, N.2
Soda, Y.3
Haraguchi, Y.4
Kitamura, T.5
Hoshino, H.6
-
147
-
-
0031982583
-
The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains
-
R. Horuk, J. Hesselgesser, Y. Zhou, D. Faulds, M. Halks-Miller, and S. Harvey The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains J Biol Chem 273 1998 386 391
-
(1998)
J Biol Chem
, vol.273
, pp. 386-391
-
-
Horuk, R.1
Hesselgesser, J.2
Zhou, Y.3
Faulds, D.4
Halks-Miller, M.5
Harvey, S.6
-
148
-
-
17544397389
-
The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1
-
H. Choe, M. Farzan, M. Konkel, K. Martin, Y. Sun, and L. Marcon The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1 J Virol 72 1998 6113 6118
-
(1998)
J Virol
, vol.72
, pp. 6113-6118
-
-
Choe, H.1
Farzan, M.2
Konkel, M.3
Martin, K.4
Sun, Y.5
Marcon, L.6
-
149
-
-
0032508407
-
Identification of CX3CR1. a chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1
-
C. Combadiere, K. Salzwedel, E.D. Smith, H.L. Tiffany, E.A. Berger, and P.M. Murphy Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1 J Biol Chem 273 1998 23799 23804
-
(1998)
J Biol Chem
, vol.273
, pp. 23799-23804
-
-
Combadiere, C.1
Salzwedel, K.2
Smith, E.D.3
Tiffany, H.L.4
Berger, E.A.5
Murphy, P.M.6
-
150
-
-
0031008794
-
STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1
-
F. Liao, G. Alkhatib, K.W. Peden, G. Sharma, E.A. Berger, and J.M. Farber STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1 J Exp Med 185 1997 2015 2023
-
(1997)
J Exp Med
, vol.185
, pp. 2015-2023
-
-
Liao, F.1
Alkhatib, G.2
Peden, K.W.3
Sharma, G.4
Berger, E.A.5
Farber, J.M.6
-
151
-
-
0034304479
-
A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo
-
M. Matloubian, A. David, S. Engel, J.E. Ryan, and J.G. Cyster A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo Nat Immunol 1 2000 298 304
-
(2000)
Nat Immunol
, vol.1
, pp. 298-304
-
-
Matloubian, M.1
David, A.2
Engel, S.3
Ryan, J.E.4
Cyster, J.G.5
-
152
-
-
0031662094
-
An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus
-
A.L. Edinger, T.L. Hoffman, M. Sharron, B. Lee, Y. Yi, and W. Choe An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus J Virol 72 1998 7934 7940
-
(1998)
J Virol
, vol.72
, pp. 7934-7940
-
-
Edinger, A.L.1
Hoffman, T.L.2
Sharron, M.3
Lee, B.4
Yi, Y.5
Choe, W.6
-
153
-
-
0030751948
-
Expression cloning of new receptors used by simian and human immunodeficiency viruses
-
H.K. Deng, D. Unutmaz, V.N. KewalRamani, and D.R. Littman Expression cloning of new receptors used by simian and human immunodeficiency viruses Nature 388 1997 296 300
-
(1997)
Nature
, vol.388
, pp. 296-300
-
-
Deng, H.K.1
Unutmaz, D.2
Kewalramani, V.N.3
Littman, D.R.4
-
154
-
-
0030007839
-
A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3
-
M. Heiber, A. Marchese, T. Nguyen, H.H. Heng, S.R. George, and B.F. O'Dowd A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3 Genomics 32 1996 462 465
-
(1996)
Genomics
, vol.32
, pp. 462-465
-
-
Heiber, M.1
Marchese, A.2
Nguyen, T.3
Heng, H.H.4
George, S.R.5
O'Dowd, B.F.6
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