메뉴 건너뛰기




Volumn 29, Issue 2-3, 1996, Pages 297-307

Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type

Author keywords

Anti HIV agents: Bicyclams; Resistance: JM3100

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0029916728     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(95)00936-1     Document Type: Article
Times cited : (41)

References (28)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., Gendelman, H., Koenig, S., Folks, T., Willey, R., Rabson, A. and Martin, M. (1986) Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59, 284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.7
  • 2
    • 0023636684 scopus 로고
    • Rivabirin antagonizes inhibitory effects of pyrimidine 2′,3′-dideoxynucleosides but enhances inhibitory effects of purine 2′,3′-dideoxynucleosides on replication of human immunodeficiency virus in vitro
    • Baba, M., Pauwels, R., Balzarini, J., Herdewijn, P., De Clercq, E. and Desmyter, J. (1987) Rivabirin antagonizes inhibitory effects of pyrimidine 2′,3′-dideoxynucleosides but enhances inhibitory effects of purine 2′,3′-dideoxynucleosides on replication of human immunodeficiency virus in vitro. Antimicrob. Agents Chemother. 31, 1613-1617.
    • (1987) Antimicrob. Agents Chemother. , vol.31 , pp. 1613-1617
    • Baba, M.1    Pauwels, R.2    Balzarini, J.3    Herdewijn, P.4    De Clercq, E.5    Desmyter, J.6
  • 3
    • 0027363224 scopus 로고
    • Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
    • Balzarini, J., Karlsson, A., Pérez-Pérez, M., Camarasa, M., Tarpley, W. and De Clercq, E. (1993) Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus. Virology 196, 576-585.
    • (1993) Virology , vol.196 , pp. 576-585
    • Balzarini, J.1    Karlsson, A.2    Pérez-Pérez, M.3    Camarasa, M.4    Tarpley, W.5    De Clercq, E.6
  • 4
    • 0029067663 scopus 로고
    • Synthesis and structure-activity relationship of phenylenebis(-methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker
    • Bridger, G., Skerlj, R., Thornton, D., et al. (1995) Synthesis and structure-activity relationship of phenylenebis(-methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker. J. Med. Chem. 38, 366-378.
    • (1995) J. Med. Chem. , vol.38 , pp. 366-378
    • Bridger, G.1    Skerlj, R.2    Thornton, D.3
  • 5
    • 0027081705 scopus 로고
    • Human immunodeficiency virus inhibitors targeted at virus-cell fusion and/or viral uncoating
    • De Clercq, E. (1992) Human immunodeficiency virus inhibitors targeted at virus-cell fusion and/or viral uncoating. Int. J. lmmunother. 8, 115-123.
    • (1992) Int. J. Lmmunother. , vol.8 , pp. 115-123
    • De Clercq, E.1
  • 6
    • 0026683326 scopus 로고
    • Potent and selective inhibition of human immunodeficiency virus (HIV-1 and HIV-2) replication by a class of bicyclams interacting with a viral uncoating event
    • De Clercq, E., Yamamoto, N., Pauwels, R., et al. (1992) Potent and selective inhibition of human immunodeficiency virus (HIV-1 and HIV-2) replication by a class of bicyclams interacting with a viral uncoating event. Proc. Natl. Acad. Sci. U.S.A. 89, 5286-5290.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 5286-5290
    • De Clercq, E.1    Yamamoto, N.2    Pauwels, R.3
  • 7
    • 0028209166 scopus 로고
    • Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM 3100
    • De Clercq, E., Yamamoto N., Pauwels, R., et al. (1994) Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM 3100. Antimicrob. Agents Chemother. 38, 668-674.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 668-674
    • De Clercq, E.1    Yamamoto, N.2    Pauwels, R.3
  • 8
    • 0003973947 scopus 로고    scopus 로고
    • The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication
    • De Vreese, K., Kofler-Mongold, V., Leutgeb, C., et al. (1996a) The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication. J. Virol., 70, 689-696.
    • (1996) J. Virol. , vol.70 , pp. 689-696
    • De Vreese, K.1    Kofler-Mongold, V.2    Leutgeb, C.3
  • 9
    • 0029939009 scopus 로고    scopus 로고
    • The bicyclams, a new class of potent human immunodeficiency virus inhibitors, block viral entry after binding
    • in press
    • De Vreese, K., Reymen, D., Griffin, P., et al. (1996b) The bicyclams, a new class of potent human immunodeficiency virus inhibitors, block viral entry after binding. Antiviral Res., in press.
    • (1996) Antiviral Res.
    • De Vreese, K.1    Reymen, D.2    Griffin, P.3
  • 10
    • 0002130413 scopus 로고
    • Mutation rates and rapid evolution of RNA viruses
    • S.S. Morse (Ed), Raven Press, New York
    • Domingo, E. and Holland, J. (1994) Mutation rates and rapid evolution of RNA viruses. In: S.S. Morse (Ed), Evolutionary Biology of Viruses, pp. 161 184. Raven Press, New York.
    • (1994) Evolutionary Biology of Viruses , pp. 161-184
    • Domingo, E.1    Holland, J.2
  • 11
    • 0028327101 scopus 로고
    • Crystal structure of the principal neutralization site of HIV-1
    • Ghiara, J., Stura, E., Satanfield, R., Profy, A. and Wilson, I. (1994) Crystal structure of the principal neutralization site of HIV-1. Science 264, 82-85.
    • (1994) Science , vol.264 , pp. 82-85
    • Ghiara, J.1    Stura, E.2    Satanfield, R.3    Profy, A.4    Wilson, I.5
  • 13
    • 0026465275 scopus 로고
    • Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxycytidine
    • Gu, Z., Gao, Q., Li, X., Parniak, M. and Wainberg, M. (1992) Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxycytidine. J. Virol. 66, 7128-7135.
    • (1992) J. Virol. , vol.66 , pp. 7128-7135
    • Gu, Z.1    Gao, Q.2    Li, X.3    Parniak, M.4    Wainberg, M.5
  • 14
    • 0022404296 scopus 로고
    • Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4: An application in a plaque assay
    • Harada, S., Koyanagi, Y. and Yamamoto, N. (1985) Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4: an application in a plaque assay. Science 229, 563-566.
    • (1985) Science , vol.229 , pp. 563-566
    • Harada, S.1    Koyanagi, Y.2    Yamamoto, N.3
  • 16
    • 0026036042 scopus 로고
    • Zidovudine resistance predicted by direct detection of mutations in DNA from human immunodeficiency virus infected lymphocytes
    • Larder, B., Kellam, P. and Kemp, S. (1991) Zidovudine resistance predicted by direct detection of mutations in DNA from human immunodeficiency virus infected lymphocytes. AIDS 5, 137-144.
    • (1991) AIDS , vol.5 , pp. 137-144
    • Larder, B.1    Kellam, P.2    Kemp, S.3
  • 17
    • 0028988479 scopus 로고
    • pol gene quasispecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • Najera, L. Holguin, A., Quiñones-Mateu, M., et al. (1995) pol Gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J. Virol. 69, 23-31.
    • (1995) J. Virol. , vol.69 , pp. 23-31
    • Najera, L.1    Holguin, A.2    Quiñones-Mateu, M.3
  • 18
    • 0023687234 scopus 로고
    • Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
    • Pauwels, R., Balzarini, J., Baba, M., et al. (1988) Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J. Virol. Methods 20, 309-321.
    • (1988) J. Virol. Methods , vol.20 , pp. 309-321
    • Pauwels, R.1    Balzarini, J.2    Baba, M.3
  • 19
    • 0025014499 scopus 로고
    • Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
    • Pauwels, R., Andries, K., Desmyter, J., et al. (1990) Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives. Nature 343, 470-474.
    • (1990) Nature , vol.343 , pp. 470-474
    • Pauwels, R.1    Andries, K.2    Desmyter, J.3
  • 20
    • 0027407551 scopus 로고
    • Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of α-amlinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase
    • Pauwels, R., Andries, K., Debyser, Z., et al. (1993) Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of α-amlinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase. Proc. Natl. Acad. Sci. U.S.A. 90, 1711-1715.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 1711-1715
    • Pauwels, R.1    Andries, K.2    Debyser, Z.3
  • 21
    • 0025756141 scopus 로고
    • Three-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudine
    • Prichard, M., Prichard, L., Baguley, W., Nassiri, M. and Shipman, C. (1990) Three-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudine. Antimicrob. Agents Chemother. 35, 1060-1065.
    • (1990) Antimicrob. Agents Chemother. , vol.35 , pp. 1060-1065
    • Prichard, M.1    Prichard, L.2    Baguley, W.3    Nassiri, M.4    Shipman, C.5
  • 22
    • 0025765798 scopus 로고
    • Sulphated cyclodextrins are potent anti-HIV agents acting synergistically with 2′,3′-dideoxynucleoside analogues
    • Schols, D., De Clercq, E., Witvrouw, M., et al. (1991) Sulphated cyclodextrins are potent anti-HIV agents acting synergistically with 2′,3′-dideoxynucleoside analogues. Antiviral Chem. Chemother. 2, 45-53.
    • (1991) Antiviral Chem. Chemother. , vol.2 , pp. 45-53
    • Schols, D.1    De Clercq, E.2    Witvrouw, M.3
  • 23
    • 0025950055 scopus 로고
    • Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
    • St.Clair, M., Martin, J. and Tudor-Williams, G. (1991) Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 253, 1557-1559.
    • (1991) Science , vol.253 , pp. 1557-1559
    • St.Clair, M.1    Martin, J.2    Tudor-Williams, G.3
  • 24
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
    • Tisdale, M., Kemp, S., Parry, N. and Larder, B. (1993) Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc. Natl. Acad. Sci. U.S.A. 90, 5653-5656.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.2    Parry, N.3    Larder, B.4
  • 25
    • 0027957547 scopus 로고
    • Characterization of HIV-1 strains isolated from patients treated with TIBO R82913
    • Vandamme, A.-M., Debyser, Z., Pauwels, R., et al. (1994) Characterization of HIV-1 strains isolated from patients treated with TIBO R82913. AIDS Res. Hum. Retrovir. 10, 39-46.
    • (1994) AIDS Res. Hum. Retrovir. , vol.10 , pp. 39-46
    • Vandamme, A.-M.1    Debyser, Z.2    Pauwels, R.3
  • 26
    • 0028146612 scopus 로고
    • Activity of a sulfated polysaccharide extracted from the red seaweed Aghardiella tenera against human immunodeficiency virus and other enveloped viruses
    • Witvrouw, M., Esté, J.A., Quiñones-Mateu, M., et al. (1994a) Activity of a sulfated polysaccharide extracted from the red seaweed Aghardiella tenera against human immunodeficiency virus and other enveloped viruses. Antiviral Chem. Chemother. 5, 297-303.
    • (1994) Antiviral Chem. Chemother. , vol.5 , pp. 297-303
    • Witvrouw, M.1    Esté, J.A.2    Quiñones-Mateu, M.3
  • 27
    • 0028149715 scopus 로고
    • Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses
    • Witvrouw, M., Desmyter, J. and De Clercq, E. (1994b) Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses. Antiviral Chem. Chemother. 5, 345-359.
    • (1994) Antiviral Chem. Chemother. , vol.5 , pp. 345-359
    • Witvrouw, M.1    Desmyter, J.2    De Clercq, E.3
  • 28
    • 0030051924 scopus 로고    scopus 로고
    • Pharmacokinetics of the anti-HIV bicyclam SID791 (JM3100) in rabbits, as determined by both analytical and bioassay methods
    • Witvrouw, M., Sifert, J.M., Henson, G., Martellucci, S.A., Desmyter, J. and De Clercq, E. (1996) Pharmacokinetics of the anti-HIV bicyclam SID791 (JM3100) in rabbits, as determined by both analytical and bioassay methods. Antiviral Chem. Chemother., 7, 27-30.
    • (1996) Antiviral Chem. Chemother. , vol.7 , pp. 27-30
    • Witvrouw, M.1    Sifert, J.M.2    Henson, G.3    Martellucci, S.A.4    Desmyter, J.5    De Clercq, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.