-
1
-
-
0022495870
-
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
-
Adachi, A., Gendelman, H., Koenig, S., Folks, T., Willey, R., Rabson, A. and Martin, M. (1986) Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59, 284-291.
-
(1986)
J. Virol.
, vol.59
, pp. 284-291
-
-
Adachi, A.1
Gendelman, H.2
Koenig, S.3
Folks, T.4
Willey, R.5
Rabson, A.6
Martin, M.7
-
2
-
-
0023636684
-
Rivabirin antagonizes inhibitory effects of pyrimidine 2′,3′-dideoxynucleosides but enhances inhibitory effects of purine 2′,3′-dideoxynucleosides on replication of human immunodeficiency virus in vitro
-
Baba, M., Pauwels, R., Balzarini, J., Herdewijn, P., De Clercq, E. and Desmyter, J. (1987) Rivabirin antagonizes inhibitory effects of pyrimidine 2′,3′-dideoxynucleosides but enhances inhibitory effects of purine 2′,3′-dideoxynucleosides on replication of human immunodeficiency virus in vitro. Antimicrob. Agents Chemother. 31, 1613-1617.
-
(1987)
Antimicrob. Agents Chemother.
, vol.31
, pp. 1613-1617
-
-
Baba, M.1
Pauwels, R.2
Balzarini, J.3
Herdewijn, P.4
De Clercq, E.5
Desmyter, J.6
-
3
-
-
0027363224
-
Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
-
Balzarini, J., Karlsson, A., Pérez-Pérez, M., Camarasa, M., Tarpley, W. and De Clercq, E. (1993) Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus. Virology 196, 576-585.
-
(1993)
Virology
, vol.196
, pp. 576-585
-
-
Balzarini, J.1
Karlsson, A.2
Pérez-Pérez, M.3
Camarasa, M.4
Tarpley, W.5
De Clercq, E.6
-
4
-
-
0029067663
-
Synthesis and structure-activity relationship of phenylenebis(-methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker
-
Bridger, G., Skerlj, R., Thornton, D., et al. (1995) Synthesis and structure-activity relationship of phenylenebis(-methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker. J. Med. Chem. 38, 366-378.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 366-378
-
-
Bridger, G.1
Skerlj, R.2
Thornton, D.3
-
5
-
-
0027081705
-
Human immunodeficiency virus inhibitors targeted at virus-cell fusion and/or viral uncoating
-
De Clercq, E. (1992) Human immunodeficiency virus inhibitors targeted at virus-cell fusion and/or viral uncoating. Int. J. lmmunother. 8, 115-123.
-
(1992)
Int. J. Lmmunother.
, vol.8
, pp. 115-123
-
-
De Clercq, E.1
-
6
-
-
0026683326
-
Potent and selective inhibition of human immunodeficiency virus (HIV-1 and HIV-2) replication by a class of bicyclams interacting with a viral uncoating event
-
De Clercq, E., Yamamoto, N., Pauwels, R., et al. (1992) Potent and selective inhibition of human immunodeficiency virus (HIV-1 and HIV-2) replication by a class of bicyclams interacting with a viral uncoating event. Proc. Natl. Acad. Sci. U.S.A. 89, 5286-5290.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 5286-5290
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
-
7
-
-
0028209166
-
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM 3100
-
De Clercq, E., Yamamoto N., Pauwels, R., et al. (1994) Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM 3100. Antimicrob. Agents Chemother. 38, 668-674.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 668-674
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
-
8
-
-
0003973947
-
The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication
-
De Vreese, K., Kofler-Mongold, V., Leutgeb, C., et al. (1996a) The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication. J. Virol., 70, 689-696.
-
(1996)
J. Virol.
, vol.70
, pp. 689-696
-
-
De Vreese, K.1
Kofler-Mongold, V.2
Leutgeb, C.3
-
9
-
-
0029939009
-
The bicyclams, a new class of potent human immunodeficiency virus inhibitors, block viral entry after binding
-
in press
-
De Vreese, K., Reymen, D., Griffin, P., et al. (1996b) The bicyclams, a new class of potent human immunodeficiency virus inhibitors, block viral entry after binding. Antiviral Res., in press.
-
(1996)
Antiviral Res.
-
-
De Vreese, K.1
Reymen, D.2
Griffin, P.3
-
10
-
-
0002130413
-
Mutation rates and rapid evolution of RNA viruses
-
S.S. Morse (Ed), Raven Press, New York
-
Domingo, E. and Holland, J. (1994) Mutation rates and rapid evolution of RNA viruses. In: S.S. Morse (Ed), Evolutionary Biology of Viruses, pp. 161 184. Raven Press, New York.
-
(1994)
Evolutionary Biology of Viruses
, pp. 161-184
-
-
Domingo, E.1
Holland, J.2
-
11
-
-
0028327101
-
Crystal structure of the principal neutralization site of HIV-1
-
Ghiara, J., Stura, E., Satanfield, R., Profy, A. and Wilson, I. (1994) Crystal structure of the principal neutralization site of HIV-1. Science 264, 82-85.
-
(1994)
Science
, vol.264
, pp. 82-85
-
-
Ghiara, J.1
Stura, E.2
Satanfield, R.3
Profy, A.4
Wilson, I.5
-
12
-
-
0028932336
-
Current antiviral agents
-
Goldthorpe, S., Kinchington, D. and Lovelidge, D. (1995) Current antiviral agents. Int. Antiviral News 3, 92-98.
-
(1995)
Int. Antiviral News
, vol.3
, pp. 92-98
-
-
Goldthorpe, S.1
Kinchington, D.2
Lovelidge, D.3
-
13
-
-
0026465275
-
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxycytidine
-
Gu, Z., Gao, Q., Li, X., Parniak, M. and Wainberg, M. (1992) Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxycytidine. J. Virol. 66, 7128-7135.
-
(1992)
J. Virol.
, vol.66
, pp. 7128-7135
-
-
Gu, Z.1
Gao, Q.2
Li, X.3
Parniak, M.4
Wainberg, M.5
-
14
-
-
0022404296
-
Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4: An application in a plaque assay
-
Harada, S., Koyanagi, Y. and Yamamoto, N. (1985) Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4: an application in a plaque assay. Science 229, 563-566.
-
(1985)
Science
, vol.229
, pp. 563-566
-
-
Harada, S.1
Koyanagi, Y.2
Yamamoto, N.3
-
15
-
-
0028077124
-
V3-mediated heparin neutralization of HIV type 1
-
Javaherian, K., Khiroya, R., Quinlan, C., Boyd, J. and Hanham, K. (1995) V3-mediated heparin neutralization of HIV type 1. AIDS Res. Hum. Retroviruses 10, 1421-1423.
-
(1995)
AIDS Res. Hum. Retroviruses
, vol.10
, pp. 1421-1423
-
-
Javaherian, K.1
Khiroya, R.2
Quinlan, C.3
Boyd, J.4
Hanham, K.5
-
16
-
-
0026036042
-
Zidovudine resistance predicted by direct detection of mutations in DNA from human immunodeficiency virus infected lymphocytes
-
Larder, B., Kellam, P. and Kemp, S. (1991) Zidovudine resistance predicted by direct detection of mutations in DNA from human immunodeficiency virus infected lymphocytes. AIDS 5, 137-144.
-
(1991)
AIDS
, vol.5
, pp. 137-144
-
-
Larder, B.1
Kellam, P.2
Kemp, S.3
-
17
-
-
0028988479
-
pol gene quasispecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy
-
Najera, L. Holguin, A., Quiñones-Mateu, M., et al. (1995) pol Gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J. Virol. 69, 23-31.
-
(1995)
J. Virol.
, vol.69
, pp. 23-31
-
-
Najera, L.1
Holguin, A.2
Quiñones-Mateu, M.3
-
18
-
-
0023687234
-
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
-
Pauwels, R., Balzarini, J., Baba, M., et al. (1988) Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J. Virol. Methods 20, 309-321.
-
(1988)
J. Virol. Methods
, vol.20
, pp. 309-321
-
-
Pauwels, R.1
Balzarini, J.2
Baba, M.3
-
19
-
-
0025014499
-
Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
-
Pauwels, R., Andries, K., Desmyter, J., et al. (1990) Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives. Nature 343, 470-474.
-
(1990)
Nature
, vol.343
, pp. 470-474
-
-
Pauwels, R.1
Andries, K.2
Desmyter, J.3
-
20
-
-
0027407551
-
Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of α-amlinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase
-
Pauwels, R., Andries, K., Debyser, Z., et al. (1993) Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of α-amlinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase. Proc. Natl. Acad. Sci. U.S.A. 90, 1711-1715.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 1711-1715
-
-
Pauwels, R.1
Andries, K.2
Debyser, Z.3
-
21
-
-
0025756141
-
Three-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudine
-
Prichard, M., Prichard, L., Baguley, W., Nassiri, M. and Shipman, C. (1990) Three-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudine. Antimicrob. Agents Chemother. 35, 1060-1065.
-
(1990)
Antimicrob. Agents Chemother.
, vol.35
, pp. 1060-1065
-
-
Prichard, M.1
Prichard, L.2
Baguley, W.3
Nassiri, M.4
Shipman, C.5
-
22
-
-
0025765798
-
Sulphated cyclodextrins are potent anti-HIV agents acting synergistically with 2′,3′-dideoxynucleoside analogues
-
Schols, D., De Clercq, E., Witvrouw, M., et al. (1991) Sulphated cyclodextrins are potent anti-HIV agents acting synergistically with 2′,3′-dideoxynucleoside analogues. Antiviral Chem. Chemother. 2, 45-53.
-
(1991)
Antiviral Chem. Chemother.
, vol.2
, pp. 45-53
-
-
Schols, D.1
De Clercq, E.2
Witvrouw, M.3
-
23
-
-
0025950055
-
Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
-
St.Clair, M., Martin, J. and Tudor-Williams, G. (1991) Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 253, 1557-1559.
-
(1991)
Science
, vol.253
, pp. 1557-1559
-
-
St.Clair, M.1
Martin, J.2
Tudor-Williams, G.3
-
24
-
-
0027285372
-
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
-
Tisdale, M., Kemp, S., Parry, N. and Larder, B. (1993) Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc. Natl. Acad. Sci. U.S.A. 90, 5653-5656.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 5653-5656
-
-
Tisdale, M.1
Kemp, S.2
Parry, N.3
Larder, B.4
-
25
-
-
0027957547
-
Characterization of HIV-1 strains isolated from patients treated with TIBO R82913
-
Vandamme, A.-M., Debyser, Z., Pauwels, R., et al. (1994) Characterization of HIV-1 strains isolated from patients treated with TIBO R82913. AIDS Res. Hum. Retrovir. 10, 39-46.
-
(1994)
AIDS Res. Hum. Retrovir.
, vol.10
, pp. 39-46
-
-
Vandamme, A.-M.1
Debyser, Z.2
Pauwels, R.3
-
26
-
-
0028146612
-
Activity of a sulfated polysaccharide extracted from the red seaweed Aghardiella tenera against human immunodeficiency virus and other enveloped viruses
-
Witvrouw, M., Esté, J.A., Quiñones-Mateu, M., et al. (1994a) Activity of a sulfated polysaccharide extracted from the red seaweed Aghardiella tenera against human immunodeficiency virus and other enveloped viruses. Antiviral Chem. Chemother. 5, 297-303.
-
(1994)
Antiviral Chem. Chemother.
, vol.5
, pp. 297-303
-
-
Witvrouw, M.1
Esté, J.A.2
Quiñones-Mateu, M.3
-
27
-
-
0028149715
-
Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses
-
Witvrouw, M., Desmyter, J. and De Clercq, E. (1994b) Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses. Antiviral Chem. Chemother. 5, 345-359.
-
(1994)
Antiviral Chem. Chemother.
, vol.5
, pp. 345-359
-
-
Witvrouw, M.1
Desmyter, J.2
De Clercq, E.3
-
28
-
-
0030051924
-
Pharmacokinetics of the anti-HIV bicyclam SID791 (JM3100) in rabbits, as determined by both analytical and bioassay methods
-
Witvrouw, M., Sifert, J.M., Henson, G., Martellucci, S.A., Desmyter, J. and De Clercq, E. (1996) Pharmacokinetics of the anti-HIV bicyclam SID791 (JM3100) in rabbits, as determined by both analytical and bioassay methods. Antiviral Chem. Chemother., 7, 27-30.
-
(1996)
Antiviral Chem. Chemother.
, vol.7
, pp. 27-30
-
-
Witvrouw, M.1
Sifert, J.M.2
Henson, G.3
Martellucci, S.A.4
Desmyter, J.5
De Clercq, E.6
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