Mechanisms involved in stimulation of human immunodeficiency virus type 1 replication by aminooxypentane RANTES

Journal of Virology

Volumn 75, Issue 18, 2001, Pages 8624-8638

  Marozsan, A J ^a   Torre, V S ^a   Johnson, M ^a   Ball, S C ^a   Cross, J V ^a   Templeton, D J ^a   Quinones Mateu M E ^a   Offord, R E ^a   Arts, E J ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOOXYPENTANE RANTES; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; RANTES; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS ACTIVATION; VIRUS DNA CELL DNA INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ANTI-HIV AGENTS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROVIRUSES; RANTES; RECEPTORS, CCR5; RECEPTORS, CXCR4; TRANSCRIPTION, GENETIC; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 0034881257     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.18.8624-8638.2001     Document Type: Article

References (64)

1. CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
2. Molecular mechanism of desensitization of the chemokine receptor CCR-5: Receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor
3. DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity
4. Preferential incorporation of nucleoside analogs after template switching during human immunodeficiency virus reverse transcription
5. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
6. Involvement of extracellular signal-regulated kinase module in HIV-mediated CD4 signals controlling activation of nuclear factor-kappa B and AP-1 transcription factors
7. Coreceptor use by primate lenti-viruses
8. Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA
9. Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry
10. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
11. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
12. How MAP kinases are regulated
13. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
14. Detection and analysis of HIV; isolation and quantitation of HIV in peripheral blood
15. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
16. RANTES-induced T cell activation correlates with CD3 expression
17. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
18. Identification of a major co-receptor for primary isolates of HIV-1
19. Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and RANTES beta-chemokines
20. Coreceptor use by primate lentiviruses
21. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
22. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
23. A synthetic inhibitor of the mitogen-activated protein kinase cascade
24. An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus
25. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection
26. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
27. + T lymphocytes
28. Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
29. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia
30. Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor
31. Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase
32. Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: Evidence for differential gene expression
33. CC-chemokines enhance the replication of T-tropic strains of HIV-1 in CD4(+) T cells: Role of signal transduction
34. STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1
35. HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation
36. Opposite effects of SDF-1 on human immunodeficiency virus type 1 replication
37. Genetic acceleration of AIDS progression by a promoter variant of CCR5
38. CCR5 promoter polymorphism and HIV-1 disease progression
39. Factors secreted by human T lymphotropic virus type 1 (HTLV-I)-infected cells can enhance or inhibit replication of HIV-1 in HTLV-1-uninfected cells: Implications for in vivo coinfection with HTLV-1 and HIV-1
40. Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway
41. Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian immunodeficiency virus to Jurkat T cells expressing CCR5 receptor
42. + T lymphocytes
43. A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression
44. LTR and tat variability of HIV-1 isolates from patients with divergent rates of disease progression
45. Similarities and differences in RANTES- and (AOP)-RANTES-triggered signals: Implications for chemotaxis
46. The biology of chemokines and their receptors
47. Chemokines and HIV replication
48. RANTES and MCP-3 inhibit the replication of T-cell-tropic human immunodeficiency virus type 1 strains (SF-2, MN, and HE)
49. Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro
50. Endocytosis and recycling of the HIV coreceptor CCR5
51. Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
52. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry
53. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression
54. Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1
55. Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs
56. The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity
57. Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines
58. Divergent regulation of HIV-1 replication in PBMC of infected individuals by CC chemokines: Suppression by RANTES, MIP-1alpha, and MCP-3, and enhancement by MCP-1
59. + T lymphocytes: R5 but not X4 viruses replicate in the absence of T-cell receptor restimulation
60. Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coreceptor complex
61. Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans
62. Chemokines: Understanding their role in T-lymphocyte biology
63. Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein
64. Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway