메뉴 건너뛰기




Volumn 386, Issue 8, 2005, Pages 713-724

Splicing of a rare class of introns by the U12-dependent spliceosome

Author keywords

Pre mRNA splicing; U11 U12 snRNP; U12 dependent spliceosome

Indexed keywords

DROSOPHILA PROTEIN; MESSENGER RNA PRECURSOR; SMALL NUCLEAR RIBONUCLEOPROTEIN;

EID: 26844431946     PISSN: 14316730     EISSN: 14316730     Source Type: Journal    
DOI: 10.1515/BC.2005.084     Document Type: Review
Times cited : (125)

References (84)
  • 1
    • 0028895417 scopus 로고
    • Exon recognition in vertebrate splicing
    • Berget, S.M. (1995). Exon recognition in vertebrate splicing. J. Biol. Chem. 270, 2411-2414.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2411-2414
    • Berget, S.M.1
  • 2
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black, D.L. (2003). Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72, 291-336.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 3
    • 0032247416 scopus 로고    scopus 로고
    • Evolutionary fates and origins of U12-type introns
    • Burge, C.B., Padgett, R.A., and Sharp, P.A. (1998). Evolutionary fates and origins of U12-type introns. Mol. Cell 2, 773-785.
    • (1998) Mol. Cell , vol.2 , pp. 773-785
    • Burge, C.B.1    Padgett, R.A.2    Sharp, P.A.3
  • 4
    • 0001468848 scopus 로고    scopus 로고
    • Splicing of precursors to mRNAs by the spliceosomes
    • 2nd edition, R.F. Gesteland, T.R. Cech and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press)
    • Burge, C.B., Tuschl, T., and Sharp, P.A. (1999). Splicing of precursors to mRNAs by the spliceosomes. In: The RNA world, 2nd edition, R.F. Gesteland, T.R. Cech and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press), pp. 525-560.
    • (1999) The RNA World , pp. 525-560
    • Burge, C.B.1    Tuschl, T.2    Sharp, P.A.3
  • 5
    • 0033792637 scopus 로고    scopus 로고
    • The question remains: Is the spliceosome a ribozyme?
    • Collins, C.A. and Guthrie, C. (2000). The question remains: is the spliceosome a ribozyme? Nat. Struct. Biol. 7, 850-854.
    • (2000) Nat. Struct. Biol. , vol.7 , pp. 850-854
    • Collins, C.A.1    Guthrie, C.2
  • 6
    • 0031306509 scopus 로고    scopus 로고
    • Terminal intron dinucleotide sequences do not distinguish between U2- and U12-dependent introns
    • Dietrich, R.C., Incorvaia, R., and Padgett, R.A. (1997). Terminal intron dinucleotide sequences do not distinguish between U2- and U12-dependent introns. Mol. Cell 1, 151-160.
    • (1997) Mol. Cell , vol.1 , pp. 151-160
    • Dietrich, R.C.1    Incorvaia, R.2    Padgett, R.A.3
  • 7
    • 0034743971 scopus 로고    scopus 로고
    • Role of the 3′ splice site in U12-dependent intron splicing
    • Dietrich, R.C., Peris, M.J., Seyboldt, A.S., and Padgett, R.A. (2001a). Role of the 3′ splice site in U12-dependent intron splicing. Mol. Cell. Biol. 21, 1942-1952.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1942-1952
    • Dietrich, R.C.1    Peris, M.J.2    Seyboldt, A.S.3    Padgett, R.A.4
  • 8
    • 0034762872 scopus 로고    scopus 로고
    • Alternative splicing of U12-dependent introns in vivo responds to purine-rich enhancers
    • Dietrich, R.C., Shukla, G.C., Fuller, J.D., and Padgett, R.A. (2001b). Alternative splicing of U12-dependent introns in vivo responds to purine-rich enhancers. RNA 7, 1378-1388.
    • (2001) RNA , vol.7 , pp. 1378-1388
    • Dietrich, R.C.1    Shukla, G.C.2    Fuller, J.D.3    Padgett, R.A.4
  • 9
    • 9344271506 scopus 로고    scopus 로고
    • Modified nucleotides at the 5′ end of human U2 snRNA are required for spliceosomal E-complex formation
    • Dönmez, G., Hartmuth, K., and Lührmann, R. (2004). Modified nucleotides at the 5′ end of human U2 snRNA are required for spliceosomal E-complex formation. RNA 10, 1925-1933.
    • (2004) RNA , vol.10 , pp. 1925-1933
    • Dönmez, G.1    Hartmuth, K.2    Lührmann, R.3
  • 10
    • 0033119176 scopus 로고    scopus 로고
    • Initial recognition of U12-dependent introns requires both U11/5′ splice-site and U12/branchpoint interactions
    • Frilander, M.J. and Steitz, J.A. (1999). Initial recognition of U12-dependent introns requires both U11/5′ splice-site and U12/branchpoint interactions. Genes Dev. 13, 851-863.
    • (1999) Genes Dev. , vol.13 , pp. 851-863
    • Frilander, M.J.1    Steitz, J.A.2
  • 11
    • 0035104772 scopus 로고    scopus 로고
    • Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome
    • Frilander, M.J. and Steitz, J.A. (2001). Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome. Mol. Cell 7, 217-226.
    • (2001) Mol. Cell , vol.7 , pp. 217-226
    • Frilander, M.J.1    Steitz, J.A.2
  • 12
    • 20344369784 scopus 로고    scopus 로고
    • Proximity of the U12 snRNA with both the 5′ splice site and the branch point during the early stages of spliceosome assembly
    • in press
    • Frilander, M.J. and Meng, X. (2005). Proximity of the U12 snRNA with both the 5′ splice site and the branch point during the early stages of spliceosome assembly. Mol. Cell. Biol., in press.
    • (2005) Mol. Cell. Biol.
    • Frilander, M.J.1    Meng, X.2
  • 13
    • 0038670209 scopus 로고    scopus 로고
    • Molecular architecture of the multiprotein splicing factor SF3b
    • Golas, M.M., Sander, B., Will, C.L., Lührmann, R., and Stark, H. (2003). Molecular architecture of the multiprotein splicing factor SF3b. Science 300, 980-984.
    • (2003) Science , vol.300 , pp. 980-984
    • Golas, M.M.1    Sander, B.2    Will, C.L.3    Lührmann, R.4    Stark, H.5
  • 14
    • 15244359121 scopus 로고    scopus 로고
    • Major conformational change in the protein complex SF3b upon integration into the spliceosomal U11/U12 di-snRNP as revealed by electron cryomicroscopy
    • Golas, M.M., Sander, B., Will, C.L., Lührmann, R., and Stark, H. (2005). Major conformational change in the protein complex SF3b upon integration into the spliceosomal U11/U12 di-snRNP as revealed by electron cryomicroscopy. Mol. Cell 17, 869-883.
    • (2005) Mol. Cell , vol.17 , pp. 869-883
    • Golas, M.M.1    Sander, B.2    Will, C.L.3    Lührmann, R.4    Stark, H.5
  • 15
    • 0030044836 scopus 로고    scopus 로고
    • Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A
    • Gozani, O., Feld, R., and Reed, R. (1996). Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes Dev. 10, 233-243.
    • (1996) Genes Dev. , vol.10 , pp. 233-243
    • Gozani, O.1    Feld, R.2    Reed, R.3
  • 16
    • 0035252410 scopus 로고    scopus 로고
    • Alternative splicing: Increasing diversity in the proteomic world
    • Graveley, B.R. (2001). Alternative splicing: increasing diversity in the proteomic world. Trends Genet. 17, 100-107.
    • (2001) Trends Genet. , vol.17 , pp. 100-107
    • Graveley, B.R.1
  • 18
    • 0028366003 scopus 로고
    • Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites
    • Hall, S.L. and Padgett, R.A. (1994). Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites. J. Mol. Biol. 239, 357-365.
    • (1994) J. Mol. Biol. , vol.239 , pp. 357-365
    • Hall, S.L.1    Padgett, R.A.2
  • 19
    • 0029989519 scopus 로고    scopus 로고
    • Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns
    • Hall, S.L. and Padgett, R.A. (1996). Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns. Science 271, 1716-1718.
    • (1996) Science , vol.271 , pp. 1716-1718
    • Hall, S.L.1    Padgett, R.A.2
  • 21
    • 0035037737 scopus 로고    scopus 로고
    • Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway
    • Hastings, M.L. and Krainer, A.R. (2001). Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway. RNA 7, 471-482.
    • (2001) RNA , vol.7 , pp. 471-482
    • Hastings, M.L.1    Krainer, A.R.2
  • 22
    • 11444258520 scopus 로고    scopus 로고
    • An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites
    • Hastings, M.L., Resta, N., Traum, D., Stella, A., Guanti, G., and Krainer, A.R. (2005). An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites. Nat. Struct. Mol. Biol. 12, 54-59.
    • (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 54-59
    • Hastings, M.L.1    Resta, N.2    Traum, D.3    Stella, A.4    Guanti, G.5    Krainer, A.R.6
  • 23
    • 0031440025 scopus 로고    scopus 로고
    • A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs
    • Horowitz, D.S., Kobayashi, R., and Krainer, A.R. (1997). A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. RNA 3, 1374-1387.
    • (1997) RNA , vol.3 , pp. 1374-1387
    • Horowitz, D.S.1    Kobayashi, R.2    Krainer, A.R.3
  • 24
    • 0031745936 scopus 로고    scopus 로고
    • Base pairing with U6atac snRNA is required for 5′ splice site activation of U12-dependent introns in vivo
    • Incorvaia, R. and Padgett, R.A. (1998). Base pairing with U6atac snRNA is required for 5′ splice site activation of U12-dependent introns in vivo. RNA 4, 709-718.
    • (1998) RNA , vol.4 , pp. 709-718
    • Incorvaia, R.1    Padgett, R.A.2
  • 25
    • 0025836071 scopus 로고
    • A reappraisal of non-consensus mRNA splice sites
    • Jackson, I.J. (1991). A reappraisal of non-consensus mRNA splice sites. Nucleic Acids Res. 19, 3795-3798.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3795-3798
    • Jackson, I.J.1
  • 26
    • 0036242097 scopus 로고    scopus 로고
    • Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
    • Jurica, M.S., Licklider, L.J., Gygi, S.R., Grigorieff, N., and Moore, M.J. (2002). Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8, 426-439.
    • (2002) RNA , vol.8 , pp. 426-439
    • Jurica, M.S.1    Licklider, L.J.2    Gygi, S.R.3    Grigorieff, N.4    Moore, M.J.5
  • 27
    • 0042671357 scopus 로고    scopus 로고
    • Pre-mRNA splicing: Awash in a sea of proteins
    • Jurica, M.S. and Moore, M.J. (2003). Pre-mRNA splicing: awash in a sea of proteins. Mol. Cell 12, 5-14.
    • (2003) Mol. Cell , vol.12 , pp. 5-14
    • Jurica, M.S.1    Moore, M.J.2
  • 28
    • 0030941474 scopus 로고    scopus 로고
    • U11 snRNA interacts in vivo with the 5′ splice site of U12-dependent (AU-AC) pre-mRNA introns
    • Kolossova, I. and Padgett, R.A. (1997). U11 snRNA interacts in vivo with the 5′ splice site of U12-dependent (AU-AC) pre-mRNA introns. RNA 3, 227-233.
    • (1997) RNA , vol.3 , pp. 227-233
    • Kolossova, I.1    Padgett, R.A.2
  • 29
    • 0035476520 scopus 로고    scopus 로고
    • A computational scan for U12-dependent introns in the human genome sequence
    • Levine, A. and Durbin, R. (2001). A computational scan for U12-dependent introns in the human genome sequence. Nucleic Acids Res. 29, 4006-4013.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4006-4013
    • Levine, A.1    Durbin, R.2
  • 30
    • 0033028397 scopus 로고    scopus 로고
    • The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes
    • Luo, H.R., Moreau, G.A., Levin, N., and Moore, M.J. (1999). The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes. RNA 5, 893-908.
    • (1999) RNA , vol.5 , pp. 893-908
    • Luo, H.R.1    Moreau, G.A.2    Levin, N.3    Moore, M.J.4
  • 31
  • 32
    • 0034640124 scopus 로고    scopus 로고
    • The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions
    • Makarov, E.M., Makarova, O.V., Achsel, T., and Lührmann, R. (2000). The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. J. Mol. Biol. 298, 567-575.
    • (2000) J. Mol. Biol. , vol.298 , pp. 567-575
    • Makarov, E.M.1    Makarova, O.V.2    Achsel, T.3    Lührmann, R.4
  • 33
    • 0037073946 scopus 로고    scopus 로고
    • Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome
    • Makarov, E.M., Makarova, O.V., Urlaub, H., Gentzel, M., Will, C.L., Wilm, M., and Lührmann, R. (2002). Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298, 2205-2208.
    • (2002) Science , vol.298 , pp. 2205-2208
    • Makarov, E.M.1    Makarova, O.V.2    Urlaub, H.3    Gentzel, M.4    Will, C.L.5    Wilm, M.6    Lührmann, R.7
  • 34
    • 0036500141 scopus 로고    scopus 로고
    • Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing
    • Makarova, O.V., Makarov, E.M., Liu, S., Vornlocher, H.P., and Lührmann, R. (2002). Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4 /U6*U5 tri-snRNP formation and pre-mRNA splicing. EMBO J. 21, 1148-1157.
    • (2002) EMBO J. , vol.21 , pp. 1148-1157
    • Makarova, O.V.1    Makarov, E.M.2    Liu, S.3    Vornlocher, H.P.4    Lührmann, R.5
  • 35
    • 3242737496 scopus 로고    scopus 로고
    • A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing
    • Makarova, O.V., Makarov, E.M., Urlaub, H., Will, C.L., Gentzel, M., Wilm, M., and Lührmann, R. (2004). A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J. 23, 2381-2391.
    • (2004) EMBO J. , vol.23 , pp. 2381-2391
    • Makarova, O.V.1    Makarov, E.M.2    Urlaub, H.3    Will, C.L.4    Gentzel, M.5    Wilm, M.6    Lührmann, R.7
  • 36
    • 0029767662 scopus 로고    scopus 로고
    • SR proteins and splicing control
    • Manley, J.L. and Tacke, R. (1996). SR proteins and splicing control. Genes Dev. 10, 1569-1579.
    • (1996) Genes Dev. , vol.10 , pp. 1569-1579
    • Manley, J.L.1    Tacke, R.2
  • 37
    • 0032707206 scopus 로고    scopus 로고
    • A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs
    • Massenet, S. and Branlant, C. (1999). A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs. RNA 5, 1495-1503.
    • (1999) RNA , vol.5 , pp. 1495-1503
    • Massenet, S.1    Branlant, C.2
  • 38
    • 0024230675 scopus 로고
    • Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc
    • Montzka, K.A. and Steitz, J.A. (1988). Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. Proc. Natl. Acad. Sci. USA 85, 8885-8889.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8885-8889
    • Montzka, K.A.1    Steitz, J.A.2
  • 39
    • 0001877802 scopus 로고
    • Splicing of precursors to mRNA by the spliceosome
    • R.F. Gesteland and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press)
    • Moore, M.J., Query, C.C., and Sharp, P.A. (1993). Splicing of precursors to mRNA by the spliceosome. In: The RNA World, R.F. Gesteland and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press), pp. 303-357.
    • (1993) The RNA World , pp. 303-357
    • Moore, M.J.1    Query, C.C.2    Sharp, P.A.3
  • 40
    • 0002340095 scopus 로고    scopus 로고
    • RNA-RNA interactions in nuclear pre-mRNA splicing
    • R.W. Simons and M. Grunberg-Manago, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press)
    • Nilsen, T.W. (1998). RNA-RNA interactions in nuclear pre-mRNA splicing. In: RNA Structure and Function, R.W. Simons and M. Grunberg-Manago, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press), pp. 279-308.
    • (1998) RNA Structure and Function , pp. 279-308
    • Nilsen, T.W.1
  • 41
    • 0033229873 scopus 로고    scopus 로고
    • Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5′ stem-loop of U4 snRNA
    • Nottrott, S., Hartmuth, K., Fabrizio, P., Urlaub, H., Vidovic, I., Ficner, R., and Lührmann, R. (1999). Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5′ stem-loop of U4 snRNA. EMBO J. 18, 6119-6133.
    • (1999) EMBO J. , vol.18 , pp. 6119-6133
    • Nottrott, S.1    Hartmuth, K.2    Fabrizio, P.3    Urlaub, H.4    Vidovic, I.5    Ficner, R.6    Lührmann, R.7
  • 42
    • 0037107418 scopus 로고    scopus 로고
    • Hierarchical, clustered protein interactions with U4/U6 snRNA: A biochemical role for U4/U6 proteins
    • Nottrott, S., Urlaub, H., and Lührmann, R. (2002). Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO J. 21, 5527-5538.
    • (2002) EMBO J. , vol.21 , pp. 5527-5538
    • Nottrott, S.1    Urlaub, H.2    Lührmann, R.3
  • 43
    • 0036213247 scopus 로고    scopus 로고
    • A revised model for U4atac/U6atac snRNA base pairing
    • Padgett, R.A. and Shukla, G.C. (2002). A revised model for U4atac/U6atac snRNA base pairing. RNA 8, 125-128.
    • (2002) RNA , vol.8 , pp. 125-128
    • Padgett, R.A.1    Shukla, G.C.2
  • 44
    • 0345169036 scopus 로고    scopus 로고
    • Splicing double: Insights from the second spliceosome
    • Patel, A.A. and Steitz, J.A. (2003). Splicing double: insights from the second spliceosome. Nat. Rev. Mol. Cell. Biol. 4, 960-970.
    • (2003) Nat. Rev. Mol. Cell. Biol. , vol.4 , pp. 960-970
    • Patel, A.A.1    Steitz, J.A.2
  • 45
    • 0037099491 scopus 로고    scopus 로고
    • The splicing of U12-type introns can be a rate-limiting step in gene expression
    • Patel, A.A., McCarthy, M., and Steitz, J.A. (2002). The splicing of U12-type introns can be a rate-limiting step in gene expression. EMBO J. 21, 3804-3815.
    • (2002) EMBO J. , vol.21 , pp. 3804-3815
    • Patel, A.A.1    McCarthy, M.2    Steitz, J.A.3
  • 46
    • 0036674269 scopus 로고    scopus 로고
    • Large-scale proteomic analysis of the human spliceosome
    • Rappsilber, J., Ryder, U., Lamond, A.I. and Mann, M. (2002). Large-scale proteomic analysis of the human spliceosome. Genome Res. 12, 1231-1245.
    • (2002) Genome Res. , vol.12 , pp. 1231-1245
    • Rappsilber, J.1    Ryder, U.2    Lamond, A.I.3    Mann, M.4
  • 47
    • 0029933504 scopus 로고    scopus 로고
    • Initial splice-site recognition and pairing during pre-mRNA splicing
    • Reed, R. (1996). Initial splice-site recognition and pairing during pre-mRNA splicing. Curr. Opin. Genet. Dev. 6, 215-220.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 215-220
    • Reed, R.1
  • 48
    • 0000189848 scopus 로고    scopus 로고
    • Spliceosome assembly
    • A.R. Krainer, ed. (Oxford, UK: IRL Press)
    • Reed, R. and Palandjian, L. (1997). Spliceosome assembly. In: Eukaryotic mRNA processing, A.R. Krainer, ed. (Oxford, UK: IRL Press), pp. 103-129.
    • (1997) Eukaryotic MRNA Processing , pp. 103-129
    • Reed, R.1    Palandjian, L.2
  • 49
    • 1842693352 scopus 로고    scopus 로고
    • Multiple roles of the SR protein family in splicing regulation
    • Sanford, J.R., Longman, D., and Caceres, J.F. (2003). Multiple roles of the SR protein family in splicing regulation. Prog. Mol. Subcell. Biol. 31, 33-58.
    • (2003) Prog. Mol. Subcell. Biol. , vol.31 , pp. 33-58
    • Sanford, J.R.1    Longman, D.2    Caceres, J.F.3
  • 51
    • 1342346504 scopus 로고    scopus 로고
    • An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes
    • Scamborova, P., Wong, A., and Steitz, J.A. (2004). An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes. Mol. Cell. Biol. 24, 1855-1869.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1855-1869
    • Scamborova, P.1    Wong, A.2    Steitz, J.A.3
  • 52
    • 4143124637 scopus 로고    scopus 로고
    • RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies
    • Schaffert, N., Hossbach, M., Heintzmann, R., Achsel, T., and Lührmann, R. (2004). RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies. EMBO J. 23, 3000-3009.
    • (2004) EMBO J. , vol.23 , pp. 3000-3009
    • Schaffert, N.1    Hossbach, M.2    Heintzmann, R.3    Achsel, T.4    Lührmann, R.5
  • 53
    • 0036240466 scopus 로고    scopus 로고
    • Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions
    • Schneider, C., Will, C.L., Makarova, O.V., Makarov, E.M., and Lührmann, R. (2002). Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Mol. Cell. Biol. 22, 3219-3229.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3219-3229
    • Schneider, C.1    Will, C.L.2    Makarova, O.V.3    Makarov, E.M.4    Lührmann, R.5
  • 54
    • 3042791298 scopus 로고    scopus 로고
    • Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila
    • Schneider, C., Will, C.L., Brosius, J., Frilander, M.J., and Lührmann, R. (2004). Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proc. Natl. Acad. Sci. USA 101, 9584-9589.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9584-9589
    • Schneider, C.1    Will, C.L.2    Brosius, J.3    Frilander, M.J.4    Lührmann, R.5
  • 55
    • 0032943029 scopus 로고    scopus 로고
    • Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plants
    • Shukla, G.C. and Padgett, R.A. (1999). Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plants. RNA 5, 525-538.
    • (1999) RNA , vol.5 , pp. 525-538
    • Shukla, G.C.1    Padgett, R.A.2
  • 56
    • 0035038510 scopus 로고    scopus 로고
    • The intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loop
    • Shukla, G.C. and Padgett, R.A. (2001). The intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loop. RNA 7, 94-105.
    • (2001) RNA , vol.7 , pp. 94-105
    • Shukla, G.C.1    Padgett, R.A.2
  • 57
    • 0036285645 scopus 로고    scopus 로고
    • A catalytically active group II intron domain 5 can function in the U12-dependent spliceosome
    • Shukla, G.C. and Padgett, R.A. (2002). A catalytically active group II intron domain 5 can function in the U12-dependent spliceosome. Mol. Cell 9, 1145-1150.
    • (2002) Mol. Cell , vol.9 , pp. 1145-1150
    • Shukla, G.C.1    Padgett, R.A.2
  • 58
    • 0346458700 scopus 로고    scopus 로고
    • U4 small nuclear RNA can function in both the major and minor spliceosomes
    • Shukla, G.C. and Padgett, R.A. (2004). U4 small nuclear RNA can function in both the major and minor spliceosomes. Proc. Natl. Acad. Sci. USA 101, 93-98.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 93-98
    • Shukla, G.C.1    Padgett, R.A.2
  • 59
    • 0030833215 scopus 로고    scopus 로고
    • Metal ion catalysis during splicing of premessenger RNA
    • Sontheimer, E.J., Sun, S., and Piccirilli, J.A. (1997). Metal ion catalysis during splicing of premessenger RNA. Nature 388, 801-805.
    • (1997) Nature , vol.388 , pp. 801-805
    • Sontheimer, E.J.1    Sun, S.2    Piccirilli, J.A.3
  • 60
    • 0028917214 scopus 로고
    • A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing
    • Sun, J.S. and Manley, J.L. (1995). A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing. Genes Dev. 9, 843-854.
    • (1995) Genes Dev. , vol.9 , pp. 843-854
    • Sun, J.S.1    Manley, J.L.2
  • 61
    • 0029763477 scopus 로고    scopus 로고
    • Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
    • Tarn, W.Y. and Steitz, J.A. (1996a). Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns. Science 273, 1824-1832.
    • (1996) Science , vol.273 , pp. 1824-1832
    • Tarn, W.Y.1    Steitz, J.A.2
  • 62
    • 0029863992 scopus 로고    scopus 로고
    • A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro
    • Tarn, W.Y. and Steitz, J.A. (1996b). A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro. Cell 84, 801-811.
    • (1996) Cell , vol.84 , pp. 801-811
    • Tarn, W.Y.1    Steitz, J.A.2
  • 63
    • 0030995509 scopus 로고    scopus 로고
    • Pre-mRNA splicing: The discovery of a new spliceosome doubles the challenge
    • Tarn, W.Y. and Steitz, J.A. (1997). Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge. Trends Biochem. Sci. 22, 132-137.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 132-137
    • Tarn, W.Y.1    Steitz, J.A.2
  • 64
    • 0031916381 scopus 로고    scopus 로고
    • The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins
    • Teigelkamp, S., Achsel, T., Mundt, C., Gothel, S.F., Cronshagen, U., Lane, W.S., Marahiel, M., and Lührmann, R. (1998). The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins. RNA 4, 127-141.
    • (1998) RNA , vol.4 , pp. 127-141
    • Teigelkamp, S.1    Achsel, T.2    Mundt, C.3    Gothel, S.F.4    Cronshagen, U.5    Lane, W.S.6    Marahiel, M.7    Lührmann, R.8
  • 65
    • 0035909314 scopus 로고    scopus 로고
    • Splicing-related catalysis by protein-free snRNAs
    • Valadkhan, S. and Manley, J.L. (2001). Splicing-related catalysis by protein-free snRNAs. Nature 413, 701-707.
    • (2001) Nature , vol.413 , pp. 701-707
    • Valadkhan, S.1    Manley, J.L.2
  • 66
    • 0038719932 scopus 로고    scopus 로고
    • Characterization of the catalytic activity of U2 and U6 snRNAs
    • Valadkhan, S. and Manley, J.L. (2003). Characterization of the catalytic activity of U2 and U6 snRNAs. RNA 9, 892-904.
    • (2003) RNA , vol.9 , pp. 892-904
    • Valadkhan, S.1    Manley, J.L.2
  • 67
    • 0026561544 scopus 로고
    • The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex
    • Wassarman, K.M. and Steitz, J.A. (1992). The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex. Mol. Cell. Biol. 12, 1276-1285.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1276-1285
    • Wassarman, K.M.1    Steitz, J.A.2
  • 68
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in premRNA splicing
    • Will, C.L. and Lührmann, R. (1997). Protein functions in premRNA splicing. Curr. Opin. Cell Biol. 9, 320-328.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 320-328
    • Will, C.L.1    Lührmann, R.2
  • 69
    • 0035370526 scopus 로고    scopus 로고
    • Spliceosomal UsnRNP biogenesis, structure and function
    • Will, C.L. and Lührmann, R. (2001). Spliceosomal UsnRNP biogenesis, structure and function. Curr. Opin. Cell Biol. 13, 290-301.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 290-301
    • Will, C.L.1    Lührmann, R.2
  • 70
    • 0037634375 scopus 로고    scopus 로고
    • Identification of both shared and distinct proteins in the major and minor spliceosomes
    • Will, C.L., Schneider, C., Reed, R., and Lührmann, R. (1999). Identification of both shared and distinct proteins in the major and minor spliceosomes. Science 284, 2003-2005.
    • (1999) Science , vol.284 , pp. 2003-2005
    • Will, C.L.1    Schneider, C.2    Reed, R.3    Lührmann, R.4
  • 72
    • 0037119975 scopus 로고    scopus 로고
    • Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein
    • Will, C.L., Urlaub, H., Achsel, T., Gentzel, M.,Wilm, M., and Lührmann, R. (2002). Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J. 21, 4978-4988.
    • (2002) EMBO J. , vol.21 , pp. 4978-4988
    • Will, C.L.1    Urlaub, H.2    Achsel, T.3    Gentzel, M.4    Wilm, M.5    Lührmann, R.6
  • 73
    • 2442690346 scopus 로고    scopus 로고
    • The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome
    • Will, C.L., Schneider, C., Hossbach, M., Urlaub, H., Rauhut, R., Elbashir, S., Tuschl, T., and Lührmann, R. (2004). The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 10, 929-941.
    • (2004) RNA , vol.10 , pp. 929-941
    • Will, C.L.1    Schneider, C.2    Hossbach, M.3    Urlaub, H.4    Rauhut, R.5    Elbashir, S.6    Tuschl, T.7    Lührmann, R.8
  • 74
    • 0030575916 scopus 로고    scopus 로고
    • U1-mediated exon definition interactions between AT-AC and GT-AG introns
    • Wu, Q. and Krainer, A.R. (1996). U1-mediated exon definition interactions between AT-AC and GT-AG introns. Science 274, 1005-1008.
    • (1996) Science , vol.274 , pp. 1005-1008
    • Wu, Q.1    Krainer, A.R.2
  • 75
    • 12644306849 scopus 로고    scopus 로고
    • Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs
    • Wu, Q. and Krainer, A.R. (1997). Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs. RNA 3, 586-601.
    • (1997) RNA , vol.3 , pp. 586-601
    • Wu, Q.1    Krainer, A.R.2
  • 76
    • 0031730213 scopus 로고    scopus 로고
    • Purine-rich enhancers function in the AT-AC pre-mRNA splicing pathway and do so independently of intact U1 snRNP
    • Wu, Q. and Krainer, A.R. (1998). Purine-rich enhancers function in the AT-AC pre-mRNA splicing pathway and do so independently of intact U1 snRNP. RNA 4, 1664-1673.
    • (1998) RNA , vol.4 , pp. 1664-1673
    • Wu, Q.1    Krainer, A.R.2
  • 77
    • 0032933429 scopus 로고    scopus 로고
    • AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes
    • Wu, Q. and Krainer, A.R. (1999). AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes. Mol. Cell. Biol. 19, 3225-3236.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3225-3236
    • Wu, Q.1    Krainer, A.R.2
  • 78
    • 0033576626 scopus 로고    scopus 로고
    • Functional recognition of the 3′ splice site AG by the splicing factor U2AF35
    • Wu, S., Romfo, C.M., Nilsen, T.W., and Green, M.R. (1999). Functional recognition of the 3′ splice site AG by the splicing factor U2AF35. Nature 402, 832-835.
    • (1999) Nature , vol.402 , pp. 832-835
    • Wu, S.1    Romfo, C.M.2    Nilsen, T.W.3    Green, M.R.4
  • 79
    • 1542380571 scopus 로고    scopus 로고
    • Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
    • Xu, Y.Z., Newnham, C.M., Kameoka, S., Huang, T., Konarska, M.M., and Query, C.C. (2004). Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA. EMBO J. 23, 376-385.
    • (2004) EMBO J. , vol.23 , pp. 376-385
    • Xu, Y.Z.1    Newnham, C.M.2    Kameoka, S.3    Huang, T.4    Konarska, M.M.5    Query, C.C.6
  • 80
    • 0034649666 scopus 로고    scopus 로고
    • Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome
    • Yean, S.L., Wuenschell, G., Termini, J., and Lin, R.J. (2000). Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature 408, 881-884.
    • (2000) Nature , vol.408 , pp. 881-884
    • Yean, S.L.1    Wuenschell, G.2    Termini, J.3    Lin, R.J.4
  • 81
    • 0030918785 scopus 로고    scopus 로고
    • Site-specific crosslinking of mammalian U11 and U6atac to the 5′, splice site of an AT-AC intron
    • Yu, Y.T. and Steitz, J.A. (1997). Site-specific crosslinking of mammalian U11 and U6atac to the 5′, splice site of an AT-AC intron. Proc. Natl. Acad. Sci. USA 94, 6030-6035.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6030-6035
    • Yu, Y.T.1    Steitz, J.A.2
  • 82
    • 0032189145 scopus 로고    scopus 로고
    • Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing
    • Yu, Y.T., Shu, M.D., and Steitz, J.A. (1998). Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing. EMBO J. 17, 5783-5795.
    • (1998) EMBO J. , vol.17 , pp. 5783-5795
    • Yu, Y.T.1    Shu, M.D.2    Steitz, J.A.3
  • 83
    • 0000996356 scopus 로고    scopus 로고
    • The Growing World of Small Nuclear Ribonucleoproteins
    • 2nd edition, R.F. Gesteland, T.R. Cech, and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press)
    • Yu, Y.-T., Scharl, E.C., Smith, C.M., and Steitz, J.A. (1999). The Growing World of Small Nuclear Ribonucleoproteins. In: The RNA World, 2nd edition, R.F. Gesteland, T.R. Cech, and J.F. Atkins, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press), pp. 487-524.
    • (1999) The RNA World , pp. 487-524
    • Yu, Y.-T.1    Scharl, E.C.2    Smith, C.M.3    Steitz, J.A.4
  • 84
    • 0037068447 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of the human spliceosome
    • Zhou, Z., Licklider, L.J., Gygi, S.P., and Reed, R. (2002). Comprehensive proteomic analysis of the human spliceosome. Nature 419, 182-185.
    • (2002) Nature , vol.419 , pp. 182-185
    • Zhou, Z.1    Licklider, L.J.2    Gygi, S.P.3    Reed, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.