-
1
-
-
0033587510
-
Highly active antiretroviral therapy in a large urban clinic: Risk factors for virologic failure and adverse drug reactions
-
Lucas GM, Chaisson RE, Moore RD. Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions. Ann Intern Med 1999; 131: 81-87.
-
(1999)
Ann. Intern. Med.
, vol.131
, pp. 81-87
-
-
Lucas, G.M.1
Chaisson, R.E.2
Moore, R.D.3
-
2
-
-
0033612928
-
Transmission of antiretroviral-drug-resistant HIV-1 variants
-
Yerly S, Kaiser L, Race E, Bru JP, Clavel F, Perrin L. Transmission of antiretroviral-drug-resistant HIV-1 variants. Lancet 1999; 354: 729-733.
-
(1999)
Lancet
, vol.354
, pp. 729-733
-
-
Yerly, S.1
Kaiser, L.2
Race, E.3
Bru, J.P.4
Clavel, F.5
Perrin, L.6
-
3
-
-
0032953920
-
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1 even in patients on effective combination therapy
-
Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1 even in patients on effective combination therapy. Nat Med 1999; 5: 512-517.
-
(1999)
Nat. Med.
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
-
5
-
-
0021720872
-
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
-
Klatzmann D, Champagne E, Chamaret S, Gruest J, Guetard D, Hercend T, et al. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 1984; 312: 767-768.
-
(1984)
Nature
, vol.312
, pp. 767-768
-
-
Klatzmann, D.1
Champagne, E.2
Chamaret, S.3
Gruest, J.4
Guetard, D.5
Hercend, T.6
-
6
-
-
0023878973
-
The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4
-
Landau NR, Warton M, Littman DR. The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4. Nature 1988; 334: 159-162.
-
(1988)
Nature
, vol.334
, pp. 159-162
-
-
Landau, N.R.1
Warton, M.2
Littman, D.R.3
-
7
-
-
0031985314
-
Spontaneous mutations in the env gene of the uman immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype
-
Dumonceaux J, Nisole S, Chanel C, Quivet L, Amara A, Baleux F, et al. Spontaneous mutations in the env gene of the uman immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype. J Virol 1998; 72: 512-519.
-
(1998)
J. Virol.
, vol.72
, pp. 512-519
-
-
Dumonceaux, J.1
Nisole, S.2
Chanel, C.3
Quivet, L.4
Amara, A.5
Baleux, F.6
-
8
-
-
0034751119
-
CXCR4 is down-regulated in cells infected with the CD4-independent X4 human immunodeficiency virus type 1 isolate m7NDK
-
Valente ST, Chanel C, Dumonceaux J, Olivier R, Marullo S, Briand P, et al. CXCR4 is down-regulated in cells infected with the CD4-independent X4 human immunodeficiency virus type 1 isolate m7NDK. J Virol 2001; 75: 439-447.
-
(2001)
J. Virol.
, vol.75
, pp. 439-447
-
-
Valente, S.T.1
Chanel, C.2
Dumonceaux, J.3
Olivier, R.4
Marullo, S.5
Briand, P.6
-
9
-
-
0035134242
-
Isolation of primary HIV-1 that target CD8+ T lymphocytes using CD8 as a receptor
-
Saha K, Zhang J, Gupta A, Dave R, Yimen M, Zerhouni B. Isolation of primary HIV-1 that target CD8+ T lymphocytes using CD8 as a receptor. Nat Med 2001; 7: 65-72.
-
(2001)
Nat. Med.
, vol.7
, pp. 65-72
-
-
Saha, K.1
Zhang, J.2
Gupta, A.3
Dave, R.4
Yimen, M.5
Zerhouni, B.6
-
10
-
-
0022459886
-
Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV the retrovirus of AIDS
-
Starcich BR, Hahn BH, Shaw GM, McNeely PD, Modrow S, Wolf H, et al. Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV the retrovirus of AIDS. Cell 1986; 45: 637-648.
-
(1986)
Cell
, vol.45
, pp. 637-648
-
-
Starcich, B.R.1
Hahn, B.H.2
Shaw, G.M.3
McNeely, P.D.4
Modrow, S.5
Wolf, H.6
-
11
-
-
0024282571
-
The phylogenetic history of immunodeficiency viruses
-
Smith TF, Srinivasan A, Schochetman G, Marcus M, Myers G. The phylogenetic history of immunodeficiency viruses. Nature 1988; 333: 573-575.
-
(1988)
Nature
, vol.333
, pp. 573-575
-
-
Smith, T.F.1
Srinivasan, A.2
Schochetman, G.3
Marcus, M.4
Myers, G.5
-
12
-
-
0025292252
-
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
-
Leonard CK, Spellman MW, Riddle L, Harris RJ, Thomas JN, Gregory TJ. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J Biol Chem 1990; 265: 10373-10382.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 10373-10382
-
-
Leonard, C.K.1
Spellman, M.W.2
Riddle, L.3
Harris, R.J.4
Thomas, J.N.5
Gregory, T.J.6
-
13
-
-
0025071687
-
Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant
-
LaRosa GJ, Davide JP, Weinhold K, Waterbury JA, Profy AT, Lewis JA, et al. Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant. Science 1990; 249: 932-935.
-
(1990)
Science
, vol.249
, pp. 932-935
-
-
LaRosa, G.J.1
Davide, J.P.2
Weinhold, K.3
Waterbury, J.A.4
Profy, A.T.5
Lewis, J.A.6
-
14
-
-
2442486934
-
-
Human Retroviruses and AIDS Database Theoretical Biology Los Alamos National Laboratories Los Alamos NM USA
-
Vasil S, Thakallapally R, Korber B, Foley B. Human Retroviruses and AIDS Database Theoretical Biology Los Alamos National Laboratories Los Alamos NM USA, 1998.
-
(1998)
-
-
Vasil, S.1
Thakallapally, R.2
Korber, B.3
Foley, B.4
-
15
-
-
0026785547
-
Identification and characterization of fusion and processing domains of the human immunodeficiency virus type 2 envelope glycoprotein
-
Freed EO, Myers DJ. Identification and characterization of fusion and processing domains of the human immunodeficiency virus type 2 envelope glycoprotein. J Virol 1992; 66: 5472-5478.
-
(1992)
J. Virol.
, vol.66
, pp. 5472-5478
-
-
Freed, E.O.1
Myers, D.J.2
-
16
-
-
0026592501
-
Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity
-
Page KA, Stearns SM, Littman DR. Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity. J Virol 1992; 66: 524-533.
-
(1992)
J. Virol.
, vol.66
, pp. 524-533
-
-
Page, K.A.1
Stearns, S.M.2
Littman, D.R.3
-
17
-
-
0032546952
-
Conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
-
Rizzuto CD, Wyatt R, Hernandez-Ramos N, Sun Y, Kwong PD, Hendrickson WA, et al. Conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science 1998; 280: 1949-1953.
-
(1998)
Science
, vol.280
, pp. 1949-1953
-
-
Rizzuto, C.D.1
Wyatt, R.2
Hernandez-Ramos, N.3
Sun, Y.4
Kwong, P.D.5
Hendrickson, W.A.6
-
18
-
-
0033551138
-
Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: Therapeutic and prophylactic implications
-
Wang WK, Dudek T, Essex M, Lee TH. Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: therapeutic and prophylactic implications. Proc Natl Acad Sci USA 1999; 96: 4558-4562.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4558-4562
-
-
Wang, W.K.1
Dudek, T.2
Essex, M.3
Lee, T.H.4
-
19
-
-
0005848581
-
Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein
-
Javaherian K, Langlois AJ, McDanal C, Ross KL, Eckler LI, Jellis CL, et al. Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein. Proc Natl Acad Sci USA 1989; 86: 6768-6772.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 6768-6772
-
-
Javaherian, K.1
Langlois, A.J.2
McDanal, C.3
Ross, K.L.4
Eckler, L.I.5
Jellis, C.L.6
-
20
-
-
0023687226
-
Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4
-
Skinner MA, Langlois AJ, McDanal CB, McDougal JS, Bolognesi DP, Matthews TJ. Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4. J Virol 1988; 62: 4195-4200.
-
(1988)
J. Virol.
, vol.62
, pp. 4195-4200
-
-
Skinner, M.A.1
Langlois, A.J.2
McDanal, C.B.3
McDougal, J.S.4
Bolognesi, D.P.5
Matthews, T.J.6
-
21
-
-
0021997051
-
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III
-
Allan JS, Coligan JE, Barin F, McLane MF, Sodroski JG, Rosen CA, et al. Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III. Science 1985; 228: 1091-1094.
-
(1985)
Science
, vol.228
, pp. 1091-1094
-
-
Allan, J.S.1
Coligan, J.E.2
Barin, F.3
McLane, M.F.4
Sodroski, J.G.5
Rosen, C.A.6
-
22
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998; 393: 648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
23
-
-
0033919404
-
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus
-
Kwong PD, Wyatt R, Sattentau QJ, Sodroski J, Hendrickson WA. Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus. J Virol 2000; 74: 1961-1972.
-
(2000)
J. Virol.
, vol.74
, pp. 1961-1972
-
-
Kwong, P.D.1
Wyatt, R.2
Sattentau, Q.J.3
Sodroski, J.4
Hendrickson, W.A.5
-
24
-
-
0032501955
-
Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120 AIDS
-
Binley JM, Wyatt R, Desjardins E, Kwong PD, Hendrickson W, Moore JP, et al. Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120 AIDS. Res Hum Retroviruses 1998; 14: 191-198.
-
(1998)
Res. Hum. Retroviruses
, vol.14
, pp. 191-198
-
-
Binley, J.M.1
Wyatt, R.2
Desjardins, E.3
Kwong, P.D.4
Hendrickson, W.5
Moore, J.P.6
-
25
-
-
0031566953
-
Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site
-
Ghiara JB, Ferguson DC, Satterthwait AC, Dyson HJ, Wilson I A. Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J Mol Biol 1997; 266: 31-39.
-
(1997)
J. Mol. Biol.
, vol.266
, pp. 31-39
-
-
Ghiara, J.B.1
Ferguson, D.C.2
Satterthwait, A.C.3
Dyson, H.J.4
Wilson, I.A.5
-
26
-
-
0028327101
-
Crystal structure of the principal neutralization site of HIV-1
-
Ghiara JB, Stura EA, Stanfield RL, Profy AT, Wilson IA. Crystal structure of the principal neutralization site of HIV-1. Science 1994; 264: 82-85.
-
(1994)
Science
, vol.264
, pp. 82-85
-
-
Ghiara, J.B.1
Stura, E.A.2
Stanfield, R.L.3
Profy, A.T.4
Wilson, I.A.5
-
27
-
-
0037317611
-
Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines suggesting a mechanism for coreceptor selectivity
-
Sharon M, Kessler N, Levy R, Zolla-Pazner S, Gorlach M, Anglister J. Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines suggesting a mechanism for coreceptor selectivity Structure. (Camb) 2003; 11: 225-236.
-
(2003)
Structure (Camb.)
, vol.11
, pp. 225-236
-
-
Sharon, M.1
Kessler, N.2
Levy, R.3
Zolla-Pazner, S.4
Gorlach, M.5
Anglister, J.6
-
28
-
-
0033080945
-
Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs
-
Stanfield R, Cabezas E, Satterthwait A, Stura E, Profy A, Wilson I. Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure 1999; 7: 131-142.
-
(1999)
Structure
, vol.7
, pp. 131-142
-
-
Stanfield, R.1
Cabezas, E.2
Satterthwait, A.3
Stura, E.4
Profy, A.5
Wilson, I.6
-
29
-
-
0032546844
-
The HIV-1 envelope glycoproteins: Fusogens antigens and immunogens
-
Wyatt R, Sodroski J. The HIV-1 envelope glycoproteins: fusogens antigens and immunogens. Science 1998; 280: 1884-1888.
-
(1998)
Science
, vol.280
, pp. 1884-1888
-
-
Wyatt, R.1
Sodroski, J.2
-
30
-
-
16144365650
-
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
-
Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, et al. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature 1996; 384: 179-183.
-
(1996)
Nature
, vol.384
, pp. 179-183
-
-
Wu, L.1
Gerard, N.P.2
Wyatt, R.3
Choe, H.4
Parolin, C.5
Ruffing, N.6
-
31
-
-
0005014748
-
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, et al. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996; 85: 1135-1148.
-
(1996)
Cell
, vol.85
, pp. 1135-1148
-
-
Choe, H.1
Farzan, M.2
Sun, Y.3
Sullivan, N.4
Rollins, B.5
Ponath, P.D.6
-
32
-
-
0029805881
-
Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines
-
Lapham CK, Ouyang J, Chandrasekhar B, Nguyen NY, Dimitrov DS, Golding H. Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science 1996; 274: 602-605.
-
(1996)
Science
, vol.274
, pp. 602-605
-
-
Lapham, C.K.1
Ouyang, J.2
Chandrasekhar, B.3
Nguyen, N.Y.4
Dimitrov, D.S.5
Golding, H.6
-
33
-
-
16144365317
-
CD4-dependent antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
-
Trkola A, Dragic T, Arthos J, Binley JM, Olson WC, Allaway GP, et al. CD4-dependent antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature 1996; 384: 184-187.
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
Dragic, T.2
Arthos, J.3
Binley, J.M.4
Olson, W.C.5
Allaway, G.P.6
-
34
-
-
0035047159
-
Replacement of the V3 region of gp120 with SDF-1 preserves the infectivity of T-cell line-tropic human immunodeficiency virus type 1
-
Yonezawa A, Hori T, Takaori-Kondo A, Morita R, Uchiyama T. Replacement of the V3 region of gp120 with SDF-1 preserves the infectivity of T-cell line-tropic human immunodeficiency virus type 1. J Virol 2001; 75: 4258-4267.
-
(2001)
J. Virol.
, vol.75
, pp. 4258-4267
-
-
Yonezawa, A.1
Hori, T.2
Takaori-Kondo, A.3
Morita, R.4
Uchiyama, T.5
-
35
-
-
0036333648
-
The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor
-
Cormier EG, Dragic T. The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor. J Virol 2002; 76: 8953-8957.
-
(2002)
J. Virol.
, vol.76
, pp. 8953-8957
-
-
Cormier, E.G.1
Dragic, T.2
-
36
-
-
0037333420
-
Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization
-
Suphaphiphat P, Thitithanyanont A, Paca-Uccaralertkun S, Essex M, Lee TH. Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization. J Virol 2003; 77: 3832-3837.
-
(2003)
J. Virol.
, vol.77
, pp. 3832-3837
-
-
Suphaphiphat, P.1
Thitithanyanont, A.2
Paca-Uccaralertkun, S.3
Essex, M.4
Lee, T.H.5
-
37
-
-
0029955497
-
The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine- mediated blockade of infection
-
Cocchi F, DeVico AL, Garzino-Demo A, Cara A, Gallo RC, Lusso P. The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine- mediated blockade of infection. Nat Med 1996; 2: 1244-1247.
-
(1996)
Nat. Med.
, vol.2
, pp. 1244-1247
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino-Demo, A.3
Cara, A.4
Gallo, R.C.5
Lusso, P.6
-
38
-
-
0032605777
-
Role of chemokine receptors in HIV-1 infection and pathogenesis
-
Ross TM, Bieniasz PD, Cullen BR. Role of chemokine receptors in HIV-1 infection and pathogenesis. Adv Virus Res 1999; 52: 233-267.
-
(1999)
Adv. Virus Res.
, vol.52
, pp. 233-267
-
-
Ross, T.M.1
Bieniasz, P.D.2
Cullen, B.R.3
-
39
-
-
14444288785
-
CD4-independent binding of SIV gp120 to rhesus CCR5
-
Martin KA, Wyatt R, Farzan M, Choe H, Marcon L, Desjardins E, et al. CD4-independent binding of SIV gp120 to rhesus CCR5. Science 1997; 278: 1470-1473.
-
(1997)
Science
, vol.278
, pp. 1470-1473
-
-
Martin, K.A.1
Wyatt, R.2
Farzan, M.3
Choe, H.4
Marcon, L.5
Desjardins, E.6
-
40
-
-
0031883554
-
A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5
-
Farzan M, Choe H, Vaca L, Martin K, Sun Y, Desjardins E, et al. A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5. J Virol 1998; 72: 1160-1164.
-
(1998)
J. Virol.
, vol.72
, pp. 1160-1164
-
-
Farzan, M.1
Choe, H.2
Vaca, L.3
Martin, K.4
Sun, Y.5
Desjardins, E.6
-
41
-
-
0031984539
-
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry
-
Dragic T, Trkola A, Lin SW, Nagashima KA, Kajumo F, Zhao L, et al. Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry. J Virol 1998; 72: 279-285.
-
(1998)
J. Virol.
, vol.72
, pp. 279-285
-
-
Dragic, T.1
Trkola, A.2
Lin, S.W.3
Nagashima, K.A.4
Kajumo, F.5
Zhao, L.6
-
42
-
-
0035000767
-
Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor
-
Labrosse B, Treboute C, Brelot A, Alizon M. Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor. J Virol 2001; 75: 5457-5464.
-
(2001)
J. Virol.
, vol.75
, pp. 5457-5464
-
-
Labrosse, B.1
Treboute, C.2
Brelot, A.3
Alizon, M.4
-
44
-
-
0033920212
-
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
-
Moulard M, Lortat-Jacob H, Mondor I, Roca G, Wyatt R, Sodroski J, et al. Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120. J Virol 2000; 74: 1948-1960.
-
(2000)
J. Virol.
, vol.74
, pp. 1948-1960
-
-
Moulard, M.1
Lortat-Jacob, H.2
Mondor, I.3
Roca, G.4
Wyatt, R.5
Sodroski, J.6
-
45
-
-
0034598905
-
DC-SIGN a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
-
Geijtenbeek TB, Kwon DS, Torensma R, van Vliet SJ, van Duijnhoven GC, Middel J, et al. DC-SIGN a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000; 100: 587-597.
-
(2000)
Cell
, vol.100
, pp. 587-597
-
-
Geijtenbeek, T.B.1
Kwon, D.S.2
Torensma, R.3
van Vliet, S.J.4
van Duijnhoven, G.C.5
Middel, J.6
-
46
-
-
0034598934
-
Identification of DC-SIGN a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses
-
Geijtenbeek TB, Torensma R, van Vliet SJ, van Duijnhoven GC, Adema GJ, van Kooyk Y, et al. Identification of DC-SIGN a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 2000; 100: 575-585.
-
(2000)
Cell
, vol.100
, pp. 575-585
-
-
Geijtenbeek, T.B.1
Torensma, R.2
van Vliet, S.J.3
van Duijnhoven, G.C.4
Adema, G.J.5
van Kooyk, Y.6
-
47
-
-
0025095635
-
Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein
-
Earl PL, Doms RW, Moss B. Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein. Proc Natl Acad Sci USA 1990; 87: 648-652.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 648-652
-
-
Earl, P.L.1
Doms, R.W.2
Moss, B.3
-
48
-
-
0028834461
-
A trimeric structural domain of the HIV-1 transmembrane glycoprotein
-
Lu M, Blacklow SC, Kim PS, A trimeric structural domain of the HIV-1 transmembrane glycoprotein. Nat Struct Biol 1995; 2: 1075-1082.
-
(1995)
Nat. Struct. Biol.
, vol.2
, pp. 1075-1082
-
-
Lu, M.1
Blacklow, S.C.2
Kim, P.S.3
-
49
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan DC, Fass D, Berger JM, Kim PS Core structure of gp41 from the HIV envelope glycoprotein. Cell 1997; 89: 263-273.
-
(1997)
Cell
, vol.89
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
Kim, P.S.4
-
50
-
-
0029878665
-
The ectodomain of HIV-1 env subunit gp41 forms a soluble alpha-helical rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide
-
Weissenhorn W, Wharton SA, Calder LJ, Earl PL, Moss B, Aliprandis E, et al. The ectodomain of HIV-1 env subunit gp41 forms a soluble alpha-helical rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide. EMBO J 1996; 15: 1507-1514.
-
(1996)
EMBO J.
, vol.15
, pp. 1507-1514
-
-
Weissenhorn, W.1
Wharton, S.A.2
Calder, L.J.3
Earl, P.L.4
Moss, B.5
Aliprandis, E.6
-
51
-
-
0035955695
-
Expression purification and characterization of recombinant HIV gp140 The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer
-
Zhang CW, Chishti Y, Hussey RE, Reinherz EL. Expression purification and characterization of recombinant HIV gp140 The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer. J Biol Chem 2001; 276: 39577-39585.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39577-39585
-
-
Zhang, C.W.1
Chishti, Y.2
Hussey, R.E.3
Reinherz, E.L.4
-
52
-
-
0034924823
-
Mechanisms of viral membrane fusion and its inhibition
-
Eckert DM, Kim PS. Mechanisms of viral membrane fusion and its inhibition. Annu Rev Biochem 2001; 70: 777-810.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 777-810
-
-
Eckert, D.M.1
Kim, P.S.2
-
53
-
-
0035163480
-
Conserved N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication
-
Johnson WE, Sauvron JM, Desrosiers RC. Conserved N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication. J Virol 2001; 75: 11426-11436.
-
(2001)
J. Virol.
, vol.75
, pp. 11426-11436
-
-
Johnson, W.E.1
Sauvron, J.M.2
Desrosiers, R.C.3
-
54
-
-
0030821140
-
HIV gets a taste of its own medicine
-
Cohen J. HIV gets a taste of its own medicine. Science 1997; 277: 1606.
-
(1997)
Science
, vol.277
, pp. 1606
-
-
Cohen, J.1
-
55
-
-
0027203897
-
Inhibition of HIV-1 infection by a fusion domain binding peptide from the HIV-1 envelope glycoprotein GP41
-
Jiang S, Lin K, Strick N, Neurath AR. Inhibition of HIV-1 infection by a fusion domain binding peptide from the HIV-1 envelope glycoprotein GP41. Biochem Biophys Res Commun 1993; 195: 533-538.
-
(1993)
Biochem. Biophys Res. Commun.
, vol.195
, pp. 533-538
-
-
Jiang, S.1
Lin, K.2
Strick, N.3
Neurath, A.R.4
-
56
-
-
0027959493
-
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
-
Wild CT, Shugars DC, Greenwell TK, McDanal CB, Matthews TJ. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. Proc Natl Acad Sci USA 1994; 91: 9770-9774.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9770-9774
-
-
Wild, C.T.1
Shugars, D.C.2
Greenwell, T.K.3
McDanal, C.B.4
Matthews, T.J.5
-
57
-
-
0023864652
-
A soluble CD4 protein selectively inhibits HIV replication and syncytium formation
-
Hussey RE, Richardson NE, Kowalski M, Brown NR, Chang HC, Siliciano RF, et al. A soluble CD4 protein selectively inhibits HIV replication and syncytium formation. Nature 1988; 331: 78-81.
-
(1988)
Nature
, vol.331
, pp. 78-81
-
-
Hussey, R.E.1
Richardson, N.E.2
Kowalski, M.3
Brown, N.R.4
Chang, H.C.5
Siliciano, R.F.6
-
58
-
-
0023845937
-
A soluble form of CD4 (T4) protein inhibits AIDS virus infection
-
Deen KC, McDougal JS, Inacker R, Folena-Wasserman G, Arthos J, Rosenberg J, et al. A soluble form of CD4 (T4) protein inhibits AIDS virus infection. Nature 1988; 331: 82-84.
-
(1988)
Nature
, vol.331
, pp. 82-84
-
-
Deen, K.C.1
McDougal, J.S.2
Inacker, R.3
Folena-Wasserman, G.4
Arthos, J.5
Rosenberg, J.6
-
60
-
-
0028824505
-
T30177 an oligonucleotide stabilized by an intramolecular guanosine octet is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1
-
Ojwang JO, Buckheit RW, Pommier Y, Mazumder A, De Vreese K, Esté JA, et al. T30177 an oligonucleotide stabilized by an intramolecular guanosine octet is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrob Agents Chemother 1995; 39: 2426-2435.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 2426-2435
-
-
Ojwang, J.O.1
Buckheit, R.W.2
Pommier, Y.3
Mazumder, A.4
De Vreese, K.5
Esté, J.A.6
-
61
-
-
0029062687
-
Expression and characterization of CD4-IgG2 a novel heterotetramer that neutralizes primary HIV type 1 isolates
-
Allaway GP, Davis-Bruno KL, Beaudry GA, Garcia EB, Wong EL, Ryder AM, et al. Expression and characterization of CD4-IgG2 a novel heterotetramer that neutralizes primary HIV type 1 isolates. AIDS Res Hum Retroviruses 1995; 11: 533-539.
-
(1995)
AIDS Res. Hum. Retroviruses
, vol.11
, pp. 533-539
-
-
Allaway, G.P.1
Davis-Bruno, K.L.2
Beaudry, G.A.3
Garcia, E.B.4
Wong, E.L.5
Ryder, A.M.6
-
62
-
-
0033914939
-
Single-dose safety pharmacology and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV- infected adults
-
Jacobson JM, Lowy I, Fletcher CV, O'Neill TJ, Tran DN, Ketas TJ, et al. Single-dose safety pharmacology and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV- infected adults. J Infect Dis 2000; 182: 326-329.
-
(2000)
J. Infect. Dis.
, vol.182
, pp. 326-329
-
-
Jacobson, J.M.1
Lowy, I.2
Fletcher, C.V.3
O'Neill, T.J.4
Tran, D.N.5
Ketas, T.J.6
-
64
-
-
0141680855
-
Discovery of 4-benzoyl-1-[(4-methoxy-1H-pyrrolo[23- b] pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions
-
Wang T, Zhang Z, Wallace OB, Deshpande M, Fang H, Yang Z, et al. Discovery of 4-benzoyl-1-[(4-methoxy-1H-pyrrolo[23- b] pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. J Med Chem 2003; 46: 4236-4239.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4236-4239
-
-
Wang, T.1
Zhang, Z.2
Wallace, O.B.3
Deshpande, M.4
Fang, H.5
Yang, Z.6
-
65
-
-
0141703204
-
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding
-
Lin PF, Blair W, Wang T, Spicer T, Guo Q, Zhou N, et al. A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding. Proc Natl Acad Sci USA 2003; 100: 11013-11018.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11013-11018
-
-
Lin, P.F.1
Blair, W.2
Wang, T.3
Spicer, T.4
Guo, Q.5
Zhou, N.6
-
66
-
-
0141856289
-
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions
-
Guo Q, Ho HT, Dicker I, Fan L, Zhou N, Friborg J, et al. Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol 2003; 77: 10528-10536.
-
(2003)
J. Virol.
, vol.77
, pp. 10528-10536
-
-
Guo, Q.1
Ho, H.T.2
Dicker, I.3
Fan, L.4
Zhou, N.5
Friborg, J.6
-
67
-
-
0029417004
-
Identification of RANTES MIP-1 alpha and MIP-1 beta as the major HIV- suppressive factors produced by CD8+ T cells
-
Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. Identification of RANTES MIP-1 alpha and MIP-1 beta as the major HIV- suppressive factors produced by CD8+ T cells. Science 1995; 270: 1811-1815.
-
(1995)
Science
, vol.270
, pp. 1811-1815
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino-Demo, A.3
Arya, S.K.4
Gallo, R.C.5
Lusso, P.6
-
68
-
-
0030749666
-
HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: Independence from G protein signaling and importance of coreceptor downmodulation
-
Alkhatib G, Locati M, Kennedy PE, Murphy PM, Berger EA. HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation. Virology 1997; 234: 340-348
-
(1997)
Virology
, vol.234
, pp. 340-348
-
-
Alkhatib, G.1
Locati, M.2
Kennedy, P.E.3
Murphy, P.M.4
Berger, E.A.5
-
69
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul CC, Farzan M, Choe H, Parolin C, Clark-Lewis I, Sodroski J, et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996; 382: 829-833.
-
(1996)
Nature
, vol.382
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
Parolin, C.4
Clark-Lewis, I.5
Sodroski, J.6
-
70
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T- cell-line-adapted HIV-1
-
Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T- cell-line-adapted HIV-1. Nature 1996; 382: 833-835.
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.L.5
Arenzana-Seisdedos, F.6
-
71
-
-
0030745286
-
HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
-
Amara A, Gall SL, Schwartz O, Salamero J, Montes M, Loetscher P, et al. HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med 1997; 186: 139-146.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 139-146
-
-
Amara, A.1
Gall, S.L.2
Schwartz, O.3
Salamero, J.4
Montes, M.5
Loetscher, P.6
-
72
-
-
0030951442
-
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
-
Simmons G, Clapham PR, Picard L, Offlord RE, Rosenkilde MM, Schwartz TW, et al. Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science 1997; 276: 276-279.
-
(1997)
Science
, vol.276
, pp. 276-279
-
-
Simmons, G.1
Clapham, P.R.2
Picard, L.3
Offlord, R.E.4
Rosenkilde, M.M.5
Schwartz, T.W.6
-
73
-
-
0032564406
-
Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity
-
Meucci O, Fatatis A, Simen AA, Bushell TJ, Gray PW, Miller RJ. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc Natl Acad Sci USA 1998; 95: 14500-14505.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14500-14505
-
-
Meucci, O.1
Fatatis, A.2
Simen, A.A.3
Bushell, T.J.4
Gray, P.W.5
Miller, R.J.6
-
74
-
-
0031982583
-
The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains
-
Horuk R, Hesselgesser J, Zhou Y, Faulds D, Halks-Miller M, Harvey S, et al. The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains. J Biol Chem 1998; 273: 386-391.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 386-391
-
-
Horuk, R.1
Hesselgesser, J.2
Zhou, Y.3
Faulds, D.4
Halks-Miller, M.5
Harvey, S.6
-
75
-
-
0032550337
-
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
-
Mack M, Luckow B, Nelson PJ, Cihak J, Simmons G, Clapham P R, et al. Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity. J Exp Med 1998; 187: 1215-1224.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1215-1224
-
-
Mack, M.1
Luckow, B.2
Nelson, P.J.3
Cihak, J.4
Simmons, G.5
Clapham, P.R.6
-
76
-
-
0030773515
-
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
-
Doranz BJ, Grovit-Ferbas K, Sharron MP, Mao SH, Goetz MB, Daar ES, et al. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J Exp Med 1997; 186: 1395-1400.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1395-1400
-
-
Doranz, B.J.1
Grovit-Ferbas, K.2
Sharron, M.P.3
Mao, S.H.4
Goetz, M.B.5
Daar, E.S.6
-
77
-
-
0030780377
-
A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
-
Murakami T, Nakajima T, Koyanagi Y, Tachibana K, Fujii N, Tamamura H, et al. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection. J Exp Med 1997; 186: 1389-1393.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1389-1393
-
-
Murakami, T.1
Nakajima, T.2
Koyanagi, Y.3
Tachibana, K.4
Fujii, N.5
Tamamura, H.6
-
78
-
-
0036027903
-
Anti-HIV activity of a novel aminoglycoside-arginine conjugate
-
Cabrera C, Gutierrez A, Barretina J, Blanco J, Litovchick A, Lapidot A, et al. Anti-HIV activity of a novel aminoglycoside-arginine conjugate. Antiviral Res 2002; 53: 1-8.
-
(2002)
Antiviral Res.
, vol.53
, pp. 1-8
-
-
Cabrera, C.1
Gutierrez, A.2
Barretina, J.3
Blanco, J.4
Litovchick, A.5
Lapidot, A.6
-
79
-
-
0034192188
-
Anti-human immunodeficiency virus activity of novel aminoglycoside- arginine conjugates at early stages of infection
-
Cabrera C, Gutierrez A, Blanco J, Barretina J, Litovchick A, Lapidot A, et al. Anti-human immunodeficiency virus activity of novel aminoglycoside- arginine conjugates at early stages of infection. AIDS Res Hum Retroviruses 2000; 16: 627-634.
-
(2000)
AIDS Res. Hum. Retroviruses
, vol.16
, pp. 627-634
-
-
Cabrera, C.1
Gutierrez, A.2
Blanco, J.3
Barretina, J.4
Litovchick, A.5
Lapidot, A.6
-
80
-
-
0033971512
-
A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: Inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry
-
Daelemans D, Schols D, Witvrouw M, Pannecouque C, Hatse S, van Dooren S, et al. A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry. Mol Pharmacol 2000; 57: 116-124.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 116-124
-
-
Daelemans, D.1
Schols, D.2
Witvrouw, M.3
Pannecouque, C.4
Hatse, S.5
van Dooren, S.6
-
81
-
-
0032895276
-
Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor
-
Este JA, Cabrera C, De Clercq E, Struyf S, Van Damme J, Bridger G, et al. Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor. Mol Pharmacol 1999; 55: 67-73.
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 67-73
-
-
Este, J.A.1
Cabrera, C.2
De Clercq, E.3
Struyf, S.4
Van Damme, J.5
Bridger, G.6
-
82
-
-
0031891516
-
AMD3100 a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
Donzella GA, Schols D, Lin SW, Esté JA, Nagashima KA, Maddon PJ, et al. AMD3100 a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat Med 1998; 4: 72-77.
-
(1998)
Nat. Med.
, vol.4
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
Esté, J.A.4
Nagashima, K.A.5
Maddon, P.J.6
-
83
-
-
0030835663
-
Bicyclams a class of potent anti-HIV agents are targeted at the HIV coreceptor fusin/CXCR-4
-
Schols D, Este JA, Henson G, De Clercq E. Bicyclams a class of potent anti-HIV agents are targeted at the HIV coreceptor fusin/CXCR-4. Antiviral Res 1997; 35: 147-156.
-
(1997)
Antiviral Res.
, vol.35
, pp. 147-156
-
-
Schols, D.1
Este, J.A.2
Henson, G.3
De Clercq, E.4
-
84
-
-
0030830661
-
Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
-
Schols D, Struyf S, Van Damme J, Esté JA, Henson G, De Clercq E. Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J Exp Med 1997; 186: 1383-1388.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1383-1388
-
-
Schols, D.1
Struyf, S.2
Van Damme, J.3
Esté, J.A.4
Henson, G.5
De Clercq, E.6
-
85
-
-
0038681342
-
The bicyclam, AMD3100 story
-
De Clercq E. The bicyclam, AMD3100 story. Nat Rev Drug Discov 2003; 2: 581-587.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 581-587
-
-
De Clercq, E.1
-
86
-
-
0042563489
-
A duodenally absorbable CXC chemokine receptor 4 antagonist KRH-1636 exhibits a potent and selective anti-HIV-1 activity
-
Ichiyama K, Yokoyama-Kumakura S, Tanaka Y, Tanaka R, Hirose K, Bannai K, et al. A duodenally absorbable CXC chemokine receptor 4 antagonist KRH-1636 exhibits a potent and selective anti-HIV-1 activity. Proc Natl Acad Sci USA 2003; 17: 17.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.17
, pp. 17
-
-
Ichiyama, K.1
Yokoyama-Kumakura, S.2
Tanaka, Y.3
Tanaka, R.4
Hirose, K.5
Bannai, K.6
-
87
-
-
13044256383
-
A small-molecule nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba M, Nishimura O, Kanzaki N, Okamoto M, Sawada H, Iizawa Y, et al. A small-molecule nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc Natl Acad Sci USA 1999; 96: 5698-5703.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
-
89
-
-
0042924181
-
Virus Entry as a Target for Anti-HIV Intervention
-
Este JA. Virus Entry as a Target for Anti-HIV Intervention. Curr Med Chem 2003; 10: 1617-1632.
-
(2003)
Curr. Med. Chem.
, vol.10
, pp. 1617-1632
-
-
Este, J.A.1
-
90
-
-
0006814720
-
Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5
-
Maeda K, Yoshimura K, Shibayama S, Habashita H, Tada H, Sagawa K, et al. Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5. J Biol Chem 2001; 13: 13.
-
(2001)
J. Biol. Chem.
, vol.13
, pp. 13
-
-
Maeda, K.1
Yoshimura, K.2
Shibayama, S.3
Habashita, H.4
Tada, H.5
Sagawa, K.6
-
91
-
-
0035173073
-
Potent Broad-Spectrum Inhibition of Human Immuno-deficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140
-
Trkola A, Ketas TJ, Nagashima KA, Zhao L, Cilliers T, Morris L, et al. Potent Broad-Spectrum Inhibition of Human Immuno-deficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140. J Virol 2001; 75: 579-588.
-
(2001)
J. Virol.
, vol.75
, pp. 579-588
-
-
Trkola, A.1
Ketas, T.J.2
Nagashima, K.A.3
Zhao, L.4
Cilliers, T.5
Morris, L.6
-
92
-
-
2442604643
-
-
In The 1st IAS Conference on HIV Pathogenesis and Treatment: Buenos Aires
-
Baroudy BM. In The 1st IAS Conference on HIV Pathogenesis and Treatment: Buenos Aires 2001.
-
(2001)
-
-
Baroudy, B.M.1
-
94
-
-
0037032933
-
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
-
Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, Gomez J, et al. Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 2002; 16: 2385-2390.
-
(2002)
AIDS
, vol.16
, pp. 2385-2390
-
-
Martinez, M.A.1
Gutierrez, A.2
Armand-Ugon, M.3
Blanco, J.4
Parera, M.5
Gomez, J.6
-
95
-
-
0032577550
-
HIV entry and its inhibition
-
Chan DC, Kim PS. HIV entry and its inhibition. Cell 1998; 93: 681-684.
-
(1998)
Cell
, vol.93
, pp. 681-684
-
-
Chan, D.C.1
Kim, P.S.2
-
96
-
-
0031473771
-
Inhibition of HIV type 1 infectivity by constrained alpha-helical peptides: Implications for the viral fusion mechanism
-
Judice JK, Tom JY, Huang W, Wrin T, Vennari J, Petropoulos CJ, et al. Inhibition of HIV type 1 infectivity by constrained alpha-helical peptides: implications for the viral fusion mechanism. Proc Natl Acad Sci USA 1997; 94: 13426-13430.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13426-13430
-
-
Judice, J.K.1
Tom, J.Y.2
Huang, W.3
Wrin, T.4
Vennari, J.5
Petropoulos, C.J.6
-
97
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20 a peptide inhibitor of gp41-mediated virus entry
-
Kilby JM, Hopkins S, Venetta TM, DiMassimo B, Cloud GA, Lee JY, et al. Potent suppression of HIV-1 replication in humans by T-20 a peptide inhibitor of gp41-mediated virus entry. Nat Med 1998; 4: 1302-1307.
-
(1998)
Nat. Med.
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.M.3
DiMassimo, B.4
Cloud, G.A.5
Lee, J.Y.6
-
98
-
-
0037223692
-
Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors
-
Labrosse B, Labernardiere JL, Dam E, Trouplin V, Skrabal K, Clavel F, et al. Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors. J Virol 2003; 77: 1610-1613.
-
(2003)
J. Virol.
, vol.77
, pp. 1610-1613
-
-
Labrosse, B.1
Labernardiere, J.L.2
Dam, E.3
Trouplin, V.4
Skrabal, K.5
Clavel, F.6
-
99
-
-
0038576281
-
Enfuvirtide an HIV-1 Fusion Inhibitor for Drug-Resistant HIV Infection in North and South America
-
Lalezari JP, Henry K, O'Hearn M, Montaner JS, Piliero PJ, Trottier B, et al. Enfuvirtide an HIV-1 Fusion Inhibitor for Drug-Resistant HIV Infection in North and South America. N Engl J Med 2003; 348: 2175-2185.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
Montaner, J.S.4
Piliero, P.J.5
Trottier, B.6
-
100
-
-
2442455808
-
-
FDA drug approvals list
-
FDA drug approvals list. 2003; http://wwwfdagov/cder/foi/label/2003/0214811blpdf.
-
(2003)
-
-
-
101
-
-
0030754130
-
Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein
-
Este JA, Schols D, De Vreese K, Van Laethem K, Vandamme AM, Desmyter J, et al. Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein. Mol Pharmacol 1997; 52: 98-104.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 98-104
-
-
Este, J.A.1
Schols, D.2
De Vreese, K.3
Van Laethem, K.4
Vandamme, A.M.5
Desmyter, J.6
-
102
-
-
0031886388
-
Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir)
-
Este JA, Cabrera C, Schols D, Cherepanov P, Gutierrez A, Witvrouw M, et al. Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir). Mol Pharmacol 1998; 53: 340-345.
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 340-345
-
-
Este, J.A.1
Cabrera, C.2
Schols, D.3
Cherepanov, P.4
Gutierrez, A.5
Witvrouw, M.6
-
103
-
-
0033589780
-
Resistance of the human immunodeficiency virus to the inhibitory action of negatively charged albumins on virus binding to CD4
-
Cabrera C, Witvrouw M, Gutierrez A, Clotet B, Kuipers ME, Swart PJ, et al. Resistance of the human immunodeficiency virus to the inhibitory action of negatively charged albumins on virus binding to CD4. AIDS Res Hum Retroviruses 1999; 15: 1535-1543.
-
(1999)
AIDS Res. Hum. Retroviruses
, vol.15
, pp. 1535-1543
-
-
Cabrera, C.1
Witvrouw, M.2
Gutierrez, A.3
Clotet, B.4
Kuipers, M.E.5
Swart, P.J.6
-
104
-
-
13344277279
-
Characterization of siamycin I a human immunodeficiency virus fusion inhibitor
-
Lin PF, Samanta H, Bechtold CM, Deminie CA, Patick AK, Alam M, et al. Characterization of siamycin I a human immunodeficiency virus fusion inhibitor. Antimicrob Agents Chemother 1996; 40: 133-138.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 133-138
-
-
Lin, P.F.1
Samanta, H.2
Bechtold, C.M.3
Deminie, C.A.4
Patick, A.K.5
Alam, M.6
-
105
-
-
0003973947
-
The molecular target of bicyclams potent inhibitors of human immunodeficiency virus replication
-
de Vreese K, Kofler-Mongold V, Leutgeb C, Weber V, Vermeire K, Schacht S, et al. The molecular target of bicyclams potent inhibitors of human immunodeficiency virus replication. J Virol 1996; 70: 689-696.
-
(1996)
J. Virol.
, vol.70
, pp. 689-696
-
-
de Vreese, K.1
Kofler-Mongold, V.2
Leutgeb, C.3
Weber, V.4
Vermeire, K.5
Schacht, S.6
-
106
-
-
0031968673
-
T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor use
-
Schols D, Esté JA, Cabrera C, De Clercq E. T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor use. J Virol 1998; 72: 4032-4037.
-
(1998)
J. Virol.
, vol.72
, pp. 4032-4037
-
-
Schols, D.1
Esté, J.A.2
Cabrera, C.3
De Clercq, E.4
-
107
-
-
0034004857
-
Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs
-
Torre VS, Marozsan AJ, Albright JL, Collins KR, Hartley O, Offord RE, et al. Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs. J Virol 2000; 74: 4868-4876.
-
(2000)
J. Virol.
, vol.74
, pp. 4868-4876
-
-
Torre, V.S.1
Marozsan, A.J.2
Albright, J.L.3
Collins, K.R.4
Hartley, O.5
Offord, R.E.6
-
108
-
-
0037039380
-
HIV-1 escape from a small molecule CCR5-specific entry inhibitor does not involve CXCR4 use
-
Trkola A, Kuhmann SE, Strizki JM, Maxwell E, Ketas T, Morgan T, et al. HIV-1 escape from a small molecule CCR5-specific entry inhibitor does not involve CXCR4 use. Proc Natl Acad Sci USA 2002; 99: 395-400.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 395-400
-
-
Trkola, A.1
Kuhmann, S.E.2
Strizki, J.M.3
Maxwell, E.4
Ketas, T.5
Morgan, T.6
-
109
-
-
2442493224
-
Genotypic and phenotypic analysis of in vitro generated HIV-1 escape isoltes to the CCR5 anatagonist SCH-C 9th Conference on Retroviruses and Opportunistic Infections
-
Abstract
-
Riley J, Wojcik L, Xu S, Strizki J. Genotypic and phenotypic analysis of in vitro generated HIV-1 escape isoltes to the CCR5 anatagonist SCH-C 9th Conference on Retroviruses and Opportunistic Infections. Abstract 2002; 397-T.
-
(2002)
, pp. 397-T
-
-
Riley, J.1
Wojcik, L.2
Xu, S.3
Strizki, J.4
-
110
-
-
0033937219
-
Involvement of both the V2 and V3 regions of the CCR5-tropic human immunodeficiency virus type 1 envelope in reduced sensitivity to macrophage inflammatory protein 1alpha
-
Maeda Y, Foda M, Matsushita S, Harada S. Involvement of both the V2 and V3 regions of the CCR5-tropic human immunodeficiency virus type 1 envelope in reduced sensitivity to macrophage inflammatory protein 1alpha. J Virol 2000; 74: 1787-1793.
-
(2000)
J. Virol.
, vol.74
, pp. 1787-1793
-
-
Maeda, Y.1
Foda, M.2
Matsushita, S.3
Harada, S.4
-
111
-
-
0029938480
-
Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1
-
Klasse PJ, Moore JP. Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1. J Virol 1996; 70: 3668-3677.
-
(1996)
J. Virol.
, vol.70
, pp. 3668-3677
-
-
Klasse, P.J.1
Moore, J.P.2
-
112
-
-
0027169943
-
Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: A phenotypic characterization
-
Klasse PJ, McKeating JA. Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: a phenotypic characterization. AIDS Res Hum Retroviruses 1993; 9: 595-604.
-
(1993)
AIDS Res. Hum. Retroviruses
, vol.9
, pp. 595-604
-
-
Klasse, P.J.1
McKeating, J.A.2
-
113
-
-
0025016076
-
High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates
-
Daar ES, Li XL, Moudgil T, Ho DD. High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates. Proc Natl Acad Sci USA 1990; 87: 6574-6578.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6574-6578
-
-
Daar, E.S.1
Li, X.L.2
Moudgil, T.3
Ho, D.D.4
-
114
-
-
0037237790
-
Syndecan captures protects and transmits HIV to T lymphocytes
-
Bobardt MD, Saphire AC, Hung HC, Yu X, Van der Schueren B, Zhang Z, et al. Syndecan captures protects and transmits HIV to T lymphocytes. Immunity 2003; 18: 27-39.
-
(2003)
Immunity
, vol.18
, pp. 27-39
-
-
Bobardt, M.D.1
Saphire, A.C.2
Hung, H.C.3
Yu, X.4
Van der Schueren, B.5
Zhang, Z.6
-
115
-
-
0030832691
-
Mode of interaction of G-quartets with the integrase of human immunodeficiency virus type 1
-
Cherepanov P, Esté JA, Rando RF, Ojwang JO, Reekmans G, Steinfeld R, et al. Mode of interaction of G-quartets with the integrase of human immunodeficiency virus type 1. Mol Pharmacol 1997; 52: 771-780.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 771-780
-
-
Cherepanov, P.1
Esté, J.A.2
Rando, R.F.3
Ojwang, J.O.4
Reekmans, G.5
Steinfeld, R.6
-
116
-
-
0029939009
-
The bicyclams a new class of potent human immunodeficiency virus inhibitors block viral entry after binding
-
De Vreese K, Reymen D, Griffin P, Steinkasserer A, Werner G, Bridger GJ, et al. The bicyclams a new class of potent human immunodeficiency virus inhibitors block viral entry after binding. Antiviral Res 1996; 29: 209-219.
-
(1996)
Antiviral Res.
, vol.29
, pp. 209-219
-
-
De Vreese, K.1
Reymen, D.2
Griffin, P.3
Steinkasserer, A.4
Werner, G.5
Bridger, G.J.6
-
117
-
-
0029916728
-
Antiviral activity of the bicyclam derivative JM3100 against drug- resistant strains of human immunodeficiency virus type 1
-
Este JA, De Vreese K, Witvrouw M, Schmit JC, Vandamme AM, Anne J, et al. Antiviral activity of the bicyclam derivative JM3100 against drug- resistant strains of human immunodeficiency virus type 1. Antiviral Res 1996; 29: 297-307.
-
(1996)
Antiviral Res.
, vol.29
, pp. 297-307
-
-
Este, J.A.1
De Vreese, K.2
Witvrouw, M.3
Schmit, J.C.4
Vandamme, A.M.5
Anne, J.6
-
118
-
-
0032954383
-
T134 a small-molecule CXCR4 inhibitor has no cross-drug resistance with AMD3100 a CXCR4 antagonist with a different structure
-
Arakaki R, Tamamura H, Premanathan M, Kanbara K, Ramanan S, Mochizuki K, et al. T134 a small-molecule CXCR4 inhibitor has no cross-drug resistance with AMD3100 a CXCR4 antagonist with a different structure. J Virol 1999; 73: 1719-1723.
-
(1999)
J. Virol.
, vol.73
, pp. 1719-1723
-
-
Arakaki, R.1
Tamamura, H.2
Premanathan, M.3
Kanbara, K.4
Ramanan, S.5
Mochizuki, K.6
-
119
-
-
0034928930
-
Biological and genetic characterization of a human immunodeficiency virus strain resistant to CXCR4 antagonist T134
-
Kanbara K, Sato S, Tanuma J, Tamamura H, Gotoh K, Yoshimori M, et al. Biological and genetic characterization of a human immunodeficiency virus strain resistant to CXCR4 antagonist T134. AIDS Res Hum Retroviruses 2001; 17: 615-622.
-
(2001)
AIDS Res. Hum. Retroviruses
, vol.17
, pp. 615-622
-
-
Kanbara, K.1
Sato, S.2
Tanuma, J.3
Tamamura, H.4
Gotoh, K.5
Yoshimori, M.6
-
120
-
-
0030451775
-
Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates
-
Jansson M, Popovic M, Karlsson A, Cocchi F, Rossi P, Albert J, et al. Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates. Proc Natl Acad Sci USA 1996; 93: 15382-15387.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15382-15387
-
-
Jansson, M.1
Popovic, M.2
Karlsson, A.3
Cocchi, F.4
Rossi, P.5
Albert, J.6
-
121
-
-
0033059948
-
Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4
-
Este JA, Cabrera C, Blanco J, Gutierrez A, Bridger G, Henson G, et al. Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4. J Virol 1999; 73: 5577-5585.
-
(1999)
J. Virol.
, vol.73
, pp. 5577-5585
-
-
Este, J.A.1
Cabrera, C.2
Blanco, J.3
Gutierrez, A.4
Bridger, G.5
Henson, G.6
-
122
-
-
0042208083
-
Role of the Human Immunodeficiency Virus Type 1 Envelope Gene in Viral Fitness
-
Rangel HR, Weber J, Chakraborty B, Gutierrez A, Marotta ML, Mirza M, et al. Role of the Human Immunodeficiency Virus Type 1 Envelope Gene in Viral Fitness. J Virol 2003; 77: 9069-9073.
-
(2003)
J. Virol.
, vol.77
, pp. 9069-9073
-
-
Rangel, H.R.1
Weber, J.2
Chakraborty, B.3
Gutierrez, A.4
Marotta, M.L.5
Mirza, M.6
-
123
-
-
0033994315
-
Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo
-
Etemad-Moghadam B, Sun Y, Nicholson EK, Fernandes M, Liou K, Gomila R, et al. Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo. J Virol 2000; 74: 4433-4440.
-
(2000)
J. Virol.
, vol.74
, pp. 4433-4440
-
-
Etemad-Moghadam, B.1
Sun, Y.2
Nicholson, E.K.3
Fernandes, M.4
Liou, K.5
Gomila, R.6
-
124
-
-
0032555938
-
The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques
-
Karlsson GB, Halloran M, Schenten D, Lee J, Racz P, Tenner-Racz K, et al. The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques. J Exp Med 1998; 188: 1159-1171.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1159-1171
-
-
Karlsson, G.B.1
Halloran, M.2
Schenten, D.3
Lee, J.4
Racz, P.5
Tenner-Racz, K.6
-
125
-
-
0033766295
-
Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells
-
LaBonte JA, Patel T, Hofmann W, Sodroski J. Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells. J Virol 2000; 74: 10690-10698.
-
(2000)
J. Virol.
, vol.74
, pp. 10690-10698
-
-
LaBonte, J.A.1
Patel, T.2
Hofmann, W.3
Sodroski, J.4
-
126
-
-
0033040696
-
The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling
-
Blanco J, Jacotot E, Cabrera C, Cardona A, Clotet B, De Clercq E, et al. The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling. AIDS 1999; 13: 909-917.
-
(1999)
AIDS
, vol.13
, pp. 909-917
-
-
Blanco, J.1
Jacotot, E.2
Cabrera, C.3
Cardona, A.4
Clotet, B.5
De Clercq, E.6
-
127
-
-
0033989709
-
The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface- expressed human immunodeficiency virus type 1 envelope-induced apoptosis
-
Blanco J, Barretina J, Henson G, Bridger G, De Clercq E, Clotet B, et al. The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface- expressed human immunodeficiency virus type 1 envelope-induced apoptosis. Antimicrob Agents Chemother 2000; 44: 51-56.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 51-56
-
-
Blanco, J.1
Barretina, J.2
Henson, G.3
Bridger, G.4
De Clercq, E.5
Clotet, B.6
-
128
-
-
12244286063
-
Reduced fitness of HIV-1 resistant to CXCR4 antagonists
-
Armand-Ugon M, Quinones-Mateu ME, Gutierez A, Barretina J, Blanco J, Schols D, et al. Reduced fitness of HIV-1 resistant to CXCR4 antagonists. Antivir Ther 2003; 8: 1-8.
-
(2003)
Antivir. Ther.
, vol.8
, pp. 1-8
-
-
Armand-Ugon, M.1
Quinones-Mateu, M.E.2
Gutierez, A.3
Barretina, J.4
Blanco, J.5
Schols, D.6
-
129
-
-
7144225541
-
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant ALIVE Study Hemophilia Growth and Development Study (HGDS) Multicenter AIDS Cohort Study (MACS) Multicenter Hemophilia Cohort Study (MHCS) San Francisco City Cohort (SFCC)
-
Winkler C, Modi W, Smith MW, Nelson GW, Wu X, Carrington M, et al. Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant ALIVE Study Hemophilia Growth and Development Study (HGDS) Multicenter AIDS Cohort Study (MACS) Multicenter Hemophilia Cohort Study (MHCS) San Francisco City Cohort (SFCC). Science 1998; 279: 389-393.
-
(1998)
Science
, vol.279
, pp. 389-393
-
-
Winkler, C.1
Modi, W.2
Smith, M.W.3
Nelson, G.W.4
Wu, X.5
Carrington, M.6
-
130
-
-
0035964686
-
Stromal -cell-derived factor 1 prevents the emergence of the syncytium- inducing phenotype of HIV-1 in vivo
-
Llano A, Barretina J, Blanco J, Gutierrez A, Clotet B, Este JA. Stromal -cell-derived factor 1 prevents the emergence of the syncytium- inducing phenotype of HIV-1 in vivo. AIDS 2001; 15: 1890-1892.
-
(2001)
AIDS
, vol.15
, pp. 1890-1892
-
-
Llano, A.1
Barretina, J.2
Blanco, J.3
Gutierrez, A.4
Clotet, B.5
Este, J.A.6
-
131
-
-
0034785564
-
Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals
-
Llano A, Barretina J, Gutierrez A, Blanco J, Cabrera C, Clotet B, et al. Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals. J Virol 2001; 75: 10319-10325.
-
(2001)
J. Virol.
, vol.75
, pp. 10319-10325
-
-
Llano, A.1
Barretina, J.2
Gutierrez, A.3
Blanco, J.4
Cabrera, C.5
Clotet, B.6
-
132
-
-
0037377747
-
Interleukin-7-Dependent Production of RANTES That Correlates with Human Immunodeficiency Virus Disease Progression
-
Llano A, Barretina J, Gutierrez A, Clotet B, Este JA. Interleukin-7-Dependent Production of RANTES That Correlates with Human Immunodeficiency Virus Disease Progression. J Virol 2003; 77: 4389-4395.
-
(2003)
J. Virol.
, vol.77
, pp. 4389-4395
-
-
Llano, A.1
Barretina, J.2
Gutierrez, A.3
Clotet, B.4
Este, J.A.5
-
133
-
-
0031953133
-
Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency
-
Glushakova S, Grivel JC, Fitzgerald W, Sylwester A, Zimmerberg J, Margolis LB. Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency. Nat Med 1998; 4: 346-349.
-
(1998)
Nat. Med.
, vol.4
, pp. 346-349
-
-
Glushakova, S.1
Grivel, J.C.2
Fitzgerald, W.3
Sylwester, A.4
Zimmerberg, J.5
Margolis, L.B.6
-
134
-
-
0027422278
-
Genotypic and phenotypic characterization of HIV-1 patients with primary infection
-
Zhu T, Mo H, Wang N, Nam DS, Cao Y, Koup RA, et al. Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 1993; 261: 1179-1181.
-
(1993)
Science
, vol.261
, pp. 1179-1181
-
-
Zhu, T.1
Mo, H.2
Wang, N.3
Nam, D.S.4
Cao, Y.5
Koup, R.A.6
-
135
-
-
0032924183
-
Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants
-
Mosier DE, Picchio GR, Gulizia RJ, Sabbe R, Poignard P, Picard L, et al. Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants. J Virol 1999; 73: 3544-3550.
-
(1999)
J. Virol.
, vol.73
, pp. 3544-3550
-
-
Mosier, D.E.1
Picchio, G.R.2
Gulizia, R.J.3
Sabbe, R.4
Poignard, P.5
Picard, L.6
-
136
-
-
0141814730
-
The entry of entry inhibitors: A fusion of science and medicine
-
Moore JP, Doms RW. The entry of entry inhibitors: a fusion of science and medicine. Proc Natl Acad Sci USA 2003; 100: 10598-10602.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10598-10602
-
-
Moore, J.P.1
Doms, R.W.2
-
137
-
-
0031883832
-
Determinants of Human Immunodeficiency Virus Type 1 Resistance to gp41-Derived Inhibitory Peptides
-
Rimsky LT, Shugars DC, Matthews TJ. Determinants of Human Immunodeficiency Virus Type 1 Resistance to gp41-Derived Inhibitory Peptides. J Virol 1998; 72: 986-993.
-
(1998)
J. Virol.
, vol.72
, pp. 986-993
-
-
Rimsky, L.T.1
Shugars, D.C.2
Matthews, T.J.3
-
138
-
-
2442422244
-
-
In 8th Conference on Retroviruses and Opportunistic Infections: Chicago USA
-
Greenberg M, McDanal C, Sanfield-Oakley S, Jin L, Tremblay C, Sista P, et al. In 8th Conference on Retroviruses and Opportunistic Infections: Chicago USA, 2001.
-
(2001)
-
-
Greenberg, M.1
McDanal, C.2
Sanfield-Oakley, S.3
Jin, L.4
Tremblay, C.5
Sista, P.6
-
139
-
-
0006870818
-
Baseline genotype and prior antiretroviral history do not affect virological response to T-1249
-
Miralles G, DeMasi R, Sista P, Melby T, Duff F, Matthews T. Baseline genotype and prior antiretroviral history do not affect virological response to T-1249. Antivir Therapy 2001; 6: 3-4.
-
(2001)
Antivir. Therapy
, vol.6
, pp. 3-4
-
-
Miralles, G.1
DeMasi, R.2
Sista, P.3
Melby, T.4
Duff, F.5
Matthews, T.6
-
140
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20 a peptide inhibitor of gp41-mediated virus entry
-
Kilby JM, Hopkins S, Venetta TM, DiMassimo B, Cloud GA, Lee JY, et al. Potent suppression of HIV-1 replication in humans by T-20 a peptide inhibitor of gp41-mediated virus entry. Nat Med 1998; 4: 1302-1307.
-
(1998)
Nat. Med.
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.M.3
DiMassimo, B.4
Cloud, G.A.5
Lee, J.Y.6
-
142
-
-
0033856458
-
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
-
Derdeyn CA, Decker JM, Sfakianos JN, Wu X, O'Brien WA, Ratner L, et al. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virot 2000; 74: 8358-8367.
-
(2000)
J. Virol.
, vol.74
, pp. 8358-8367
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
Wu, X.4
O'Brien, W.A.5
Ratner, L.6
-
143
-
-
25744461950
-
Virus attachment receptor engagement and membrane fusion
-
Keystone Symposium on HIV Pathogenesis Abstract 014
-
Doms RW. Virus attachment receptor engagement and membrane fusion Keystone Symposium on HIV Pathogenesis 2002; Abstract 014.
-
(2002)
-
-
Doms, R.W.1
-
144
-
-
0034298213
-
Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100
-
Tremblay CL, Kollmann C, Giguel F, Chou TC, Hirsch MS. Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100. J Acquir Immune Defic Syndr 2000; 25: 99-102.
-
(2000)
J. Acquir. Immune. Defic. Syndr.
, vol.25
, pp. 99-102
-
-
Tremblay, C.L.1
Kollmann, C.2
Giguel, F.3
Chou, T.C.4
Hirsch, M.S.5
-
145
-
-
0029798252
-
Possible role of the V3 domain of gp120 in resistance to an amphotericin B derivative (MS8209) blocking human immunodeficiency virus entry
-
Pleskoff O, Sol N, Marrakchi H, Serlin M, Seman M, Alizon M. Possible role of the V3 domain of gp120 in resistance to an amphotericin B derivative (MS8209) blocking human immunodeficiency virus entry. J Virol 1996; 70: 8247-8251.
-
(1996)
J. Virol.
, vol.70
, pp. 8247-8251
-
-
Pleskoff, O.1
Sol, N.2
Marrakchi, H.3
Serlin, M.4
Seman, M.5
Alizon, M.6
-
146
-
-
0030781371
-
Sensitivity of human immunodeficiency virus to bicyclam derivatives is influenced by the three-dimensional structure of gp120
-
De Vreese K, Van Nerum I, Vermeire K, Anne J, De Clercq E. Sensitivity of human immunodeficiency virus to bicyclam derivatives is influenced by the three-dimensional structure of gp120. Antimicrob Agents Chemother 1997; 41: 2616-2620.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2616-2620
-
-
De Vreese, K.1
Van Nerum, I.2
Vermeire, K.3
Anne, J.4
De Clercq, E.5
-
147
-
-
0034749279
-
Determination of coreceptor usage of human immuno-deficiency virus type 1 from patient plasma samples by using a recombinant phenotypic assay
-
Trouplin V, Salvatori F, Cappello F, Obry V, Brelot A, Heveker N, et al. Determination of coreceptor usage of human immuno-deficiency virus type 1 from patient plasma samples by using a recombinant phenotypic assay. J Virol 2001; 75: 251-259.
-
(2001)
J. Virol.
, vol.75
, pp. 251-259
-
-
Trouplin, V.1
Salvatori, F.2
Cappello, F.3
Obry, V.4
Brelot, A.5
Heveker, N.6
-
148
-
-
0002142796
-
Evaluating HIV-1 co-receptor usage and inhibitors of virus entry using recombinant virus assays
-
Win T, Huang W, Yap J, Fransen S, Paxinos E, Parkin N, et al. Evaluating HIV-1 co-receptor usage and inhibitors of virus entry using recombinant virus assays. Antiviral Therapy 2001; 6: 3.
-
(2001)
Antiviral Therapy
, vol.6
, pp. 3
-
-
Win, T.1
Huang, W.2
Yap, J.3
Fransen, S.4
Paxinos, E.5
Parkin, N.6
-
149
-
-
0035811866
-
CD4(+) and CD8(+) t cell death during human immunodeficiency virus infection in vitro
-
Blanco J, Barretina J, Cabrera C, Gutierrez A, Clotet B, Este JA. CD4(+) and CD8(+) t cell death during human immunodeficiency virus infection in vitro. Virology 2001;285: 356-365.
-
(2001)
Virology
, vol.285
, pp. 356-365
-
-
Blanco, J.1
Barretina, J.2
Cabrera, C.3
Gutierrez, A.4
Clotet, B.5
Este, J.A.6
-
150
-
-
0036896463
-
Env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors
-
Fikkert V, Cherepanov P, Van Laethem K, Hantson A, Van Remoortel B, Pannecouque C, et al. env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors. Antimicrob Agents Chemother 2002, 46: 3954-3962.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 3954-3962
-
-
Fikkert, V.1
Cherepanov, P.2
Van Laethem, K.3
Hantson, A.4
Van Remoortel, B.5
Pannecouque, C.6
-
153
-
-
1842562351
-
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155
-
Madani N, Perdigoto AL, Srinivasan K, Cox JM, Chruma JJ, LaLonde J, et al. Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155 J Virol 2004; 78: 3742-3752.
-
(2004)
J. Virol.
, vol.78
, pp. 3742-3752
-
-
Madani, N.1
Perdigoto, A.L.2
Srinivasan, K.3
Cox, J.M.4
Chruma, J.J.5
LaLonde, J.6
-
154
-
-
1342300737
-
Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion
-
Holland AU, Munk C, Lucero GR, Nguyen LD, Landau NR. Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion. Virology 2004; 319: 343-352.
-
(2004)
Virology
, vol.319
, pp. 343-352
-
-
Holland, A.U.1
Munk, C.2
Lucero, G.R.3
Nguyen, L.D.4
Landau, N.R.5
-
155
-
-
0036104758
-
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: Past, present, and future perspectives
-
Campiani G, Ramunno A, Maga G, Nacci V, Fattorusso C, Catalanotti B, et al. Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives. Curr Pharm Design 2002; 8(8): 615-57.
-
(2002)
Curr. Pharm. Design
, vol.8
, Issue.8
, pp. 615-657
-
-
Campiani, G.1
Ramunno, A.2
Maga, G.3
Nacci, V.4
Fattorusso, C.5
Catalanotti, B.6
-
156
-
-
0344276472
-
Novel inhibitors of HIV integrase: The discovery of potential anti-HIV therapeutic agents
-
Nair V. Novel inhibitors of HIV integrase: the discovery of potential anti-HIV therapeutic agents. Curr Pharm Design 2003; 9(31): 2553-65.
-
(2003)
Curr. Pharm. Design
, vol.9
, Issue.31
, pp. 2553-2565
-
-
Nair, V.1
-
157
-
-
0036223082
-
Inhibitors of HIV-1 reverse transcriptase and integrase: Classical and emerging therapeutical approaches
-
Tarrago-Litvak L, Andreola ML, Fournier M, Nevinsky GA, Parissi V, de Soultrait VR, et al. Inhibitors of HIV-1 reverse transcriptase and integrase: classical and emerging therapeutical approaches. Curr Pharm Design 2002; 8(8): 595-614.
-
(2002)
Curr. Pharm. Design
, vol.8
, Issue.8
, pp. 595-614
-
-
Tarrago-Litvak, L.1
Andreola, M.L.2
Fournier, M.3
Nevinsky, G.A.4
Parissi, V.5
de Soultrait, V.R.6
|