Replacement of the V3 region of gp120 with SDF-1 preserves the infectivity of T-cell line-tropic human immunodeficiency virus type 1

Journal of Virology

Volumn 75, Issue 9, 2001, Pages 4258-4267

  Yonezawa, A ^a   Hori, T ^a   Takaori Kondo, A ^a   Morita, R ^a   Uchiyama, T ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHIMERIC PROTEIN; COMPLEMENTARY DNA; GLYCOPROTEIN GP 120; STROMAL CELL DERIVED FACTOR 1;

AMINO ACID SEQUENCE; ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; VIRUS VIRULENCE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; CELL LINE; CELL LINE, TRANSFORMED; CHEMOKINES, CXC; CYTOKINES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; LUMINESCENT PROTEINS; MACROPHAGE INFLAMMATORY PROTEIN-1; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECEPTORS, CXCR4; SOLUBILITY; T-LYMPHOCYTES; VIRION;

EID: 0035047159     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.9.4258-4267.2001     Document Type: Article

References (56)

1. CC-CKR5: A RANTES, MIP-1α. MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
2. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
3. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type I strains
4. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
5. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
6. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
7. Core structure of gp41 from the HIV envelope glycoprotein
8. Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses
9. Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity
10. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
11. The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection
12. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
13. Change in coreceptor use correlates with disease progression in HIV-1-nuclear infected individuals
14. FACS-optimized mutants of the green fluorescent protein (GFP)
15. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1
16. The CD4(T4) antigen is an essential component of the receptor for the AIDS retrovirus
17. Identification of a major co-receptor for primary isolates of HIV-1
18. Expression cloning of new receptors used by simian and human immunodeficiency viruses
19. HIV-1 membrane fusion: Target of opportunity
20. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
21. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
22. + cells is mediated by the chemokine receptor CC-CKR-5
23. HIV-1 entry cofactor: Functional cDNA cloning of seven transmembrane, G protein-coupled receptor
24. Characteristics of a human cell line transformed by DNA from human adenovirus type 5
25. cdc2 activity
26. Tissue-specific targeting of retroviral vectors through ligand-receptor interactionse
27. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
28. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and -defective viral genomes
29. Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: Evidence for limited defectiveness and complementation
30. STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1
31. + cells
32. Dissociation of gp120 from HIV-1 virions induced by soluble CD4
33. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
34. Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection
35. Use of a green fluorescent protein as a marker for human immunodeficiency virus type 1 infection
36. Production of high-titer helper-free retroviruses by transient transfection
37. Treatment of HIV tissue culture infection with monoclonal antibody-ricin A chain conjugates
38. Long-term culture of normal and neoplastic human glia
39. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
40. T-tropic human immunodeficiency virus type 1 (HIV-1)-derived V3 loop peptides directly bind to CXCR-4 and inhibit T-tropic HIV-1 infection
41. Epitopes of the CD4 antigen and HIV infection
42. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding
43. Retroviral targeted delivery
44. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene
45. Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop
46. pH independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane
47. CD4-induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: Consequences for virus entry and neutralization
48. Signal sequence trap: A cloning strategy, for secreted proteins and type I membrane protein
49. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
50. Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines
51. Atomic structure of the ectodomain from HIV-1 gp41
52. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
53. Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding
54. The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
55. The antigenic structure of the HIV gp120 envelope glycoprotein
56. A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes