CD4-independent binding of SIV gp120 to rhesus CCR5

Science

Volumn 278, Issue 5342, 1997, Pages 1470-1473

  Martin, Kathleen A ^a   Wyatt, Richard ^a   Farzan, Michael ^a   Choe, Hyeryun ^a   Marcon, Luisa ^a   Desjardins, Elizabeth ^a   Robinson, James ^a   Sodroski, Joseph ^a   Gerard, Craig ^a   Gerard, Norma P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CELL RECEPTOR; GLYCOPROTEIN GP 120; VIRUS ENVELOPE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS INFECTION; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CELL INTERACTION; VIRUS ENVELOPE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; CELL LINE; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-2; HUMANS; MACACA MULATTA; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MUTATION; RECEPTORS, CCR5; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSFECTION; VIRAL ENVELOPE PROTEINS;

EID: 14444288785     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5342.1470     Document Type: Article

References (42)

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42. We thank R. Sweet for sCD4 and the Drosophila expression system for production of envelope glycoproteins, and R. Desrosiers for the SIVmac239 env gene sequences. Supported by NIH grants AI41581 (J.S. and C.G.), HL51366 (C.G. and N.P.G.), HL36162 (N.P.G.), AI32375 (J.R.), NCI grant CA09382 (L.M.), the Institute Superiore di Sanitá and the University of Padua (LM.), the Rubenstein/Cable Fund at the Perlmutter Laboratory, and gifts from the late William McCarty-Cooper, the G. Harold and Leila Y. Mathers Charitable Foundation, and the Friends 10. The Dana-Farber Cancer Institute is the recipient of a Center for AIDS Research grant (AI-28691) and a Cancer Center grant (CA-06516) from NIH.