Possible role of the V3 domain of gp120 in resistance to an amphotericin B derivative (MS8209) blocking human immunodeficiency virus entry

Journal of Virology

Volumn 70, Issue 11, 1996, Pages 8247-8251

  Pleskoff, Olivier ^a,b   Sol, Nathalie ^a   Marrakchi, Hela ^b   Serlin, Michelle ^a,c   Seman, Michel ^b   Alizon, Marc ^a  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B DERIVATIVE; CD4 ANTIGEN; GLYCOPROTEIN GP 120; MS 8209; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PRIORITY JOURNAL; VIRUS NEUTRALIZATION;

EID: 0029798252     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.8247-8251.1996     Document Type: Article

References (39)

1. Alkhatib, G., C. Combadiere, C. C. Broder, Y. Feng, P. E. Kennedy, P. M. Murphy, and E. A. Berger. 1996. CC CKR5: a RANTES, MIP-la. MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958.
2. Aloia, R. C., H. Tian, and F. C. Jensen. 1993. Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes. Proc. Natl. Acad. Sci. USA 90:5181-5185.
3. Batinic, D., and F. A. Robey. 1992. The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides. J. Biol. Chem. 267:6664-6671.
4. Bolard, J. 1986. How do the polyene macrolides antibiotics affect the cellular membrane properties? Biochim. Biophys. Acta 864:257-304.
5. Brun-Vézinet, F., M. A. Rey, C. Katlama, P. M. Girard, D. Roulot, P. Yéni, L. Lenoble, F. Clavel, M. Alizon, S. Gadelle, J. J. Madjar, and M. Harzic. 1987. Lymphadenopathy-associated virus type 2 in AIDS and AIDS-related complex. Lancet i:128-132.
6. Callahan, L., M. Phelan, M. Mallinson, and M. A. Norcross. 1991. Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp120-CD4 interactions. J. Virol. 65:1543-1550.
7. Cefai, D., F. Hadida, M. Jung, P. Debré, J.-G. Vernin, and M. Séman. 1991. MS8209, a new amphotericin B derivative that inhibits HIV-1 replication in vitro and restores T-cell activation via the CD3/TcR in HIV-infected CD4+ cells. AIDS 5:1453-1461.
8. Chesebro, B., J. Nishio, S. Perryman, A. Cann, W. A. O'Brien, Y. Koyanagi, I. S. Y. Chen, and K. Wehrly. 1991. Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages. J. Virol. 65:5782-5789.
9. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Ponath, L. Wu, C. R. Mackay, G. LaRosa, W. Newman, N. Gerard, C. Gerard, and J. Sodroski. 1996. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135-1148.
10. Clapham, P. R., D. Blanc, and R. A. Weiss. 1991. Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus. Virology 181:703-715.
11. Clavel, F., and P. Chameau. 1994. Fusion from without directed by human immunodeficiency virus particles. J. Virol. 68:1179-1185.
12. Deng, H., R. Liu, W. Elmeier, S. Choe, D. Unutmaz, M. Burkhart, P. Di Marzio, S. Marmon, R. E. Sutton, C. M. Hill, C. B. Davis, S. C. Peiper, T. J. Schall, D. R, Littman, and N. R. Landau. 1996. Identification of a major co-receptor for primary isolates of HIV-1. Nature (London) 381:661-666.
13. Doranz, B. J., J. Rucker, Y. Yi, R. J. Smyth, M. Samson, R. C. Peiper. M. Parmentier, R. G. Collman, and R. W. Doms. 1996. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2B as fusion cofactors. Cell 85:1149-1158.
14. + cells is mediated by the chemukine receptor CC-CKR5. Nature (London) 381:667-673.
15. Feng, Y., C. C. Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane G-protein coupled receptor. Science 272:872-877.
16. Freed, E. O., and M. A. Martin. 1995. The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection, J. Biol. Chem. 270: 23883-23886.
17. Guyader, M., M. Emerman, P. Sonigo, F. Clavel, L. Montagnier, and M. Alizon. 1987. Genome organization and transactivation of the human immunodeficiency virus type 2. Nature (London) 326:662-669.
18. Hansen, J. E. S., N. M. Witzke, C. Nielsen, L. R. Mathiesen, L. S. Teglbjaerg, C. M. Nielsen, and J. O. Nielsen. 1990. Derivatives of amphotericin inhibit infection with human immunodeficiency virus in vitro by different modes of action. Antivir. Res. 14:149-160.
19. Harada, S., Y. Koyanagi, and N. Yamamoto. 1985. Infection of HTLV-III/ LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay. Science 229:566-568.
20. Harrop, H. A., D. R. Coombe, and C. C. Rider. 1994. Heparin specifically inhibits binding of V3 loop antibodies to HIV-1 gp120. an effect potentiated by CD4 binding. AIDS 8:183-192.
21. Hwang, S. R., T. J. Boyle, K. Lyerly, and B. R. Cullen. 1992. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253:71-74.
22. Linsley, P. S., J. A. Ledbetter, E. Kinney-Thomas, and S. L. Hu. 1988. Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1. J. Virol. 62:3695-3702.
23. Matsushita, S., S. Matsumi, K. Yoshimura, T. Morikita, T. Murakami, and K. Takatsuki. 1995. Neutralizing monoclonal antibodies against human immunodeficiency virus type 2 gp120. J. Virol. 69:3333-3340.
24. McKnight, A., P. R. Clapham, and R. A. Weiss. 1994. HIV-2 and SIV infection of nonprimate cell lines expressing human CD4: restrictions to replication at distinct stages. Virology 201:8-18.
25. Moore, J. P., B. A. Jameson, R. A. Weiss, and Q. J. Sattentau. 1993. The HIV-cell fusion reaction, p. 233-289. In J. Bentz (ed.), Viral fusion mechanisms. CRC Press. Boca Raton, Fla.
26. Myers, G., B. Korber, J. A. Berzofsky, R. F. Smith, and G. N. Pavlakis. 1992. Human retroviruses and AIDS. A compilation of nucleic and amino acid sequences. Los Alamos National Laboratory. Los Alamos, N.Mex.
27. Peden, K., M. Emerman, and L. Montagnier. 1991. Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-IMAL, and HIV-IELL Virology 185: 661-672.
28. Pleskoff, O., and M. Alizon. 1995. Unpublished results.
29. Pleskoff, O., M. Seman, and M. Alizon. 1995. Ampholericin B derivative blocks human immunodeficiency virus type 1 entry after CD4 binding: effect on virus-cell fusion but not on cell-cell fusion. J. Virol. 69:570-574.
30. Rey-Cuille, M. A., J. Galabru. A. Laurent-Crawford, B. Krust, L. Montagnier, and A. G. Hovanessian. 1994. HIV-2 EHO has a divergent envelope gene and induces single-cell killing by apoptosis. Virology 202:471-476.
31. Rimland, J., W. Xin, P. Sweetnam, K. Saijoh, E. J. Nestler, and R. S. Duman. 1991. Sequence and expression of a neuropeptide Y receptor cDNA. Mol. Pharmacol. 40:869-875.
32. Ryan-Graham, M. A., and K. Peden. 1995. Both virus and host components are important for the manifestation of a Nef phenotype in HIV-1 and HIV-2. Virology 213:158-168.
33. Sattentau, Q. J., and J. P. Moore. 1991. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding. J. Exp. Med. 174:407-415.
34. Schaffner, C. P., O. J. Plescia, D. Pontani, D. Sun, A. Thornton, R. S. Pandey, and P. Sarin. 1986. Anti-viral activity of amphotericin B methylester: inhibition of HTLV-III replication in cell culture. Biochem. Pharmacol. 35:4110-4113.
35. Selvam, M. P., R. A. Blay, S. Geyer, S. M. Buck, L. Pollock, R. E. Mayner, and J. S. Epstein. 1993. Inhibition of HIV-1 replication in H9 cells by Nystatin-A compared with other antiviral agents. AIDS Res. Hum. Retro-viruses 9:475-481.
36. Seman, M. Unpublished observations.
37. Shioda, T., J. A. Levy, and C. Cheng-Mayer. 1991. Macrophage and T-celL line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature (London) 349:167-169.
38. Skinner, M. A., A. J. Langlois, C. B. McDanal, J. S. McDougal, D, P. Bolognesi, and T. J. Matthews. 1988. Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4. J. Virol. 62:4195-4200.
39. Wyatt, J. R., T. A. Vickers, J. L. Roberson, R. W. J. Buckheit, T. Klimkait, E. De Baets, P. W. Davis, B. Rayner, J. L. Imbach, and D. J. Ecker. 1994. Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc. Natl. Acad. Sci. USA 91:1356-1360.