Pathway- and expression level-dependent effects of oncogenic N-Ras: p27Kip1 mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling

Molecular and Cellular Biology

Volumn 25, Issue 18, 2005, Pages 8239-8250

  Kfir, Shiri ^a   Ehrlich, Marcelo ^a,c   Goldshmid, Ayelet ^a   Liu, Xuedong ^b   Kloog, Yoel ^a   Henis, Yoav I ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF COLORADO   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; N RAS ONCOPROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P27; RAL PROTEIN; RETROVIRUS VECTOR; SMAD PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; THREONINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL CYCLE; CONTROLLED STUDY; CYTOSKELETON; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; METASTASIS; ONCOGENE N RAS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL CYCLE PROTEINS; CELL NUCLEUS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOPLASM; DNA-BINDING PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MAP KINASE KINASE KINASES; MICE; MUTATION; ONCOGENE PROTEIN P21(RAS); RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEINS;

MURINAE;

EID: 24344491428     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.18.8239-8250.2005     Document Type: Article

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