Direct Binding of the Signal-transducing Adaptor Grb2 Facilitates Down-regulation of the Cyclin-dependent Kinase Inhibitor p27Kip1

Journal of Biological Chemistry

Volumn 276, Issue 15, 2001, Pages 12084-12090

  Sugiyama, Yoriko ^a   Tomoda, Kiichiro ^a   Tanaka, Toshiaki ^a   Arata, Yukinobu ^a   Yoneda Kato, Noriko ^a   Kato, Jun Ya ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; MUTAGENESIS;

CYTOPLASM; SIGNAL TRANSDUCTION;

BIOCHEMISTRY;

ADAPTOR PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN; PROTEIN CSN5; PROTEIN GRB3 3; PROTEIN JAB1; PROTEIN P27; UNCLASSIFIED DRUG; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GRB2 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; PRIMER DNA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CYCLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME INHIBITION; GENE CONTROL; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; ANIMAL; CELL DIVISION; CELL STRAIN 3T3; CELL STRAIN COS1; CYTOLOGY; DRUG ANTAGONISM; FIBROBLAST; METABOLISM;

ANIMALIA;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL DIVISION; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DNA PRIMERS; DOWN-REGULATION; FIBROBLASTS; GRB2 ADAPTOR PROTEIN; MICE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN BINDING; PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 0035853813     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010811200     Document Type: Article

References (36)

1. Sgambato, A., Cittadini, A., Faraglia, B., and Weinstein, I. B. (2000) J. Cell. Physiol. 183, 18-27
2. Slingerland, J., and Pagano, M. (2000) J. Cell. Physiol. 183, 10-17
3. Sheaff, R. J., Groudine, M., Gordon, M., Roberts, J. M., and Clurman, B. E. (1997) Genes Dev. 11, 1464-1478
4. Vlach, J., Hennecke, S., and Amati, B. (1997) EMBO J. 16, 5334-5344
5. Tomoda, K., Kubota, Y., and Kato, J. (1999) Nature 398, 160-165
6. Carrano, A. C., Eytan, E., Hershko, A., and Pagano, M. (1999) Nat. Cell Biol. 1, 193-199
7. Sutterluty, H., Chatelain, E., Marti, A., Wirbelauer, C., Senften, M., Muller, U., and Krek, W. (1999) Nat. Cell Biol. 1, 207-214
8. Tsvetkov, L. M., Yeh, K. H., Lee, S. J., Sun, H., and Zhang, H. (1999) Curr. Biol. 9, 661-664
9. Claret, F. X., Hibi, M., Dhut, S., Toda, T., and Karin, M. (1996) Nature 383, 453-457
10. Wei, N., and Deng, X. W. (1999) Trends Genet. 15, 98-103
11. Deng, X. W., Dubiel, W., Wei, N., Hofmann, K., Mundt, K., Colicelli, J., Kato, J., Naumann, M., Segal, D., Seeger, M., Carr, A., Glickman, M., and Chamovitz, D. A. (2000) Trends Genet. 16, 202-203
12. Freilich, S., Oron, E., Kapp, Y., Nevo-Caspi, Y., Orgad, S., Segal, D., and Chamovitz, D. A. (1999) Curr. Biol. 9, 1187-1190
13. Schlessinger, J. (2000) Cell 103, 211-225
14. Birge, R. B., Knudsen, B. S., Besser, D., and Hanafusa, H. (1996) Genes Cells 1, 595-613
15. Aktas, H., Cai, H., and Cooper, G. M. (1997) Mol. Cell. Biol. 17, 3850-3857
16. Takuwa, N., and Takuwa, Y. (1997) Mol. Cell. Biol. 17, 5348-5358
17. Kawada, M., Yamagoe, S., Murakami, Y., Suzuki, K., Mizuno, S., and Uehara, Y. (1997) Oncogene 15, 629-637
18. Akamatsu, E., Tanaka, T., and Kato, J. (1998) J. Biol. Chem. 273, 16494-16500
19. Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E., and Sherr, C. J. (1993) Genes Dev. 7, 331-342
20. Chen, C., and Okayama, H. (1987) Mol. Cell. Biol. 7, 2745-2752
21. Fath, I., Schweighoffer, F., Rey, I., Multon, M. C., Boiziau, J., Duchesne, M., and Tocque, B. (1994) Science 264, 971-974
22. Nishi, K., Yoshida, M., Fujiwara, D., Nishikawa, M., Horinouchi, S., and Beppu, T. (1994) J. Biol. Chem. 269, 6320-6324
23. Diehl, J. A., Cheng, M., Roussel, M. F., and Sherr, C. J. (1998) Genes Dev. 12, 3499-3511
24. Levine, A. J. (1997) Cell 88, 323-331
25. Giaccia, A. J., and Kastan, M. B. (1998) Genes Dev. 12, 2973-2983
26. Henderson, B. R. (2000) Nat. Cell Biol. 2, 653-660
27. Kawasaki, H., Eckner, R., Yao, T.-P., Taira, K., Chiu, R., Livingston, D. M., and Yokoyama, K. K. (1998) Nature 393, 284-289
28. Kolluri, S. K., Weiss, C., Koff, A., and Gottlicher, M. (1999) Genes Dev. 13, 1742-1753
29. Hengst, L., and Reed, S. I. (1996) Science 271, 1861-1864
30. Millard, S. S., Yan, J. S., Nguyen, H., Pagano, M., Kiyokawa, H., and Koff, A. (1997) J. Biol. Chem. 272, 7093-7098
31. Millard, S. S., Vidal, A., Markus, M., Koff, A. (2000) Mol. Cell. Biol. 20, 5947-5959
32. Nakayama, K., Nagahama, H., Minamishima, Y. A., Matsumoto, M., Nakamichi, I., Kitagawa, K., Shirane, M., Tsunematsu, R., Tsukiyama, T., Ishida, N., Kitagawa, M., Nakayama, K., and Hatakeyama, S. (2000) EMBO J. 19, 2069-2081
33. Porter, P. L., Malone, K. E., Heagerty, P. J., Alexander, G. M., Gatti, L. A., Firpo, E. J., Daling, J. R., and Roberts, J. M. (1997) Nat. Med. 3, 222-225
34. Catzavelos, C., Bhattacharya, N., Ung, Y. C., Wilson, J. A., Roncari, L., Sandhu, C., Shaw, P., Yeger, H., Morava-Protzner, I., Kapusta, L., Franssen, E., Pritchard, K. I., and Slingerland, J. M. (1997) Nat. Med. 3, 227-230
35. Loda, M., Cukor, B., Tam, S. W., Lavin, P., Fiorentino, M., Draetta, G. F., Jessup, J. M., and Pagano, M. (1997) Nat. Med. 3, 231-234
36. Zhang, H., Kobayashi, R., Galaktionov, K., and Beach, D. (1995) Cell 82, 915-925