-
1
-
-
0026667482
-
Phosphorylation of the retinoblastoma protein by Cdk2
-
Akiyama, T., T. Ohuchi, S. Sumida, K. Matsumoto, and K. Toyoshima. 1992. Phosphorylation of the retinoblastoma protein by Cdk2. Proc. Natl. Acad. Sci. USA 89:7900-7904.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7900-7904
-
-
Akiyama, T.1
Ohuchi, T.2
Sumida, S.3
Matsumoto, K.4
Toyoshima, K.5
-
2
-
-
0027333421
-
Molecular aspects of mesenchymal-epithelial interactions
-
Birchmeier, C., and W. Birchmeier. 1993. Molecular aspects of mesenchymal-epithelial interactions. Annu. Rev. Cell Biol. 9:511-540.
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 511-540
-
-
Birchmeier, C.1
Birchmeier, W.2
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
4
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
-
Bussolino, F., M. F. Di Renzo, M. Ziche, E. Bocchietto, M. Olivero, L. Naldini, G. Gaudino, L. Tamagnone, A. Coffer, and P. M. Comoglio. 1992. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J. Cell Biol. 119:629-641.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 629-641
-
-
Bussolino, F.1
Di Renzo, M.F.2
Ziche, M.3
Bocchietto, E.4
Olivero, M.5
Naldini, L.6
Gaudino, G.7
Tamagnone, L.8
Coffer, A.9
Comoglio, P.M.10
-
5
-
-
0031019197
-
Cyclin D1/ Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation
-
Connell-Crowley, L., J. W. Harper, and D. W. Goodrich. 1997. Cyclin D1/ Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. Mol. Biol. Cell 8:287-301.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 287-301
-
-
Connell-Crowley, L.1
Harper, J.W.2
Goodrich, D.W.3
-
7
-
-
0029073142
-
Transforming growth factor-β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
-
Datto, M. B., Y. Li, J. F. Panus, D. J. Howe, Y. Xiong, and X. F. Wang. 1995. Transforming growth factor-β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. SCi. USA 92:5545-5549.
-
(1995)
Proc. Natl. Acad. SCi. USA
, vol.92
, pp. 5545-5549
-
-
Datto, M.B.1
Li, Y.2
Panus, J.F.3
Howe, D.J.4
Xiong, Y.5
Wang, X.F.6
-
8
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker, M. P., W. T. Parks, C. J. Frank, P. Castagnino, D. P. Bottaro, A. B. Roberts, and R. J. Lechleider. 1998. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev. 12:1587-1592.
-
(1998)
Genes Dev.
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
Lechleider, R.J.7
-
9
-
-
0026698263
-
Association of human cyclin e with a periodic G1-S phase protein kinase
-
Dulic, V., E. Lees, and S. I. Reed. 1992. Association of human cyclin E with a periodic G1-S phase protein kinase. Science 257:1958-1961.
-
(1992)
Science
, vol.257
, pp. 1958-1961
-
-
Dulic, V.1
Lees, E.2
Reed, S.I.3
-
10
-
-
0027374766
-
TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest
-
Ewen, M. E., H. K. Sluss, L. L. Whitehouse, and D. M. Livingston. 1993. TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74: 1009-1020.
-
(1993)
Cell
, vol.74
, pp. 1009-1020
-
-
Ewen, M.E.1
Sluss, H.K.2
Whitehouse, L.L.3
Livingston, D.M.4
-
11
-
-
0026657169
-
Cdc25 regulates the phosphorylation and activity of the Xenopus Cdk2 protein kinase complex
-
Gabrielli, B. G., M. S. Lee, D. H. Walker, H. Piwnica-Worms, and J. L. Maller. 1992. Cdc25 regulates the phosphorylation and activity of the Xenopus Cdk2 protein kinase complex. J. Biol. Chem. 267:18040-18046.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18040-18046
-
-
Gabrielli, B.G.1
Lee, M.S.2
Walker, D.H.3
Piwnica-Worms, H.4
Maller, J.L.5
-
12
-
-
0029119740
-
Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
-
Graña, X., and E. P. Reddy. 1995. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11:211-219.
-
(1995)
Oncogene
, vol.11
, pp. 211-219
-
-
Graña, X.1
Reddy, E.P.2
-
13
-
-
0026713875
-
Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15
-
Gu, Y., J. Rosenblatt, and D. O. Morgan. 1992. Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15. EMBO J. 11:3995-4005.
-
(1992)
EMBO J.
, vol.11
, pp. 3995-4005
-
-
Gu, Y.1
Rosenblatt, J.2
Morgan, D.O.3
-
14
-
-
0029133264
-
Cell cycle dependent effects of U.V.-radiation on p53 expression and retinoblastoma protein phosphorylation
-
Haapajärvi, T., L. Kivinen, K. Pitkänen, and M. Laiho. 1995. Cell cycle dependent effects of U.V.-radiation on p53 expression and retinoblastoma protein phosphorylation. Oncogene 11:151-159.
-
(1995)
Oncogene
, vol.11
, pp. 151-159
-
-
Haapajärvi, T.1
Kivinen, L.2
Pitkänen, K.3
Laiho, M.4
-
15
-
-
0028875086
-
Evidence for different modes of action of cyclin-dependent kinase inhibitors: P15 and p16 bind to kinases, p21 and p27 bind to cyclins
-
Hall, M., S. Bates, and G. Peters. 1995. Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins. Oncogene 11:1581-1588.
-
(1995)
Oncogene
, vol.11
, pp. 1581-1588
-
-
Hall, M.1
Bates, S.2
Peters, G.3
-
16
-
-
0028168242
-
ink4b is a potential effector of TGF-β-induced cell cycle arrest
-
ink4b is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
18
-
-
0030978315
-
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15
-
Iavarone, A., and J. Massagué. 1997. Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15. Nature 387:417-422.
-
(1997)
Nature
, vol.387
, pp. 417-422
-
-
Iavarone, A.1
Massagué, J.2
-
19
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey, P. D., A. A. Russo, K. Polyak, E. Gibbs, J. Hurwitz, J. Massagué, and N. P. Pavletich. 1995. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376:313-320.
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
Russo, A.A.2
Polyak, K.3
Gibbs, E.4
Hurwitz, J.5
Massagué, J.6
Pavletich, N.P.7
-
20
-
-
0027288908
-
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
-
Kato, J., H. Matsushime, S. W. Hiebert, M. E. Ewen, and C. J. Sherr. 1993. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev. 7:331-342.
-
(1993)
Genes Dev.
, vol.7
, pp. 331-342
-
-
Kato, J.1
Matsushime, H.2
Hiebert, S.W.3
Ewen, M.E.4
Sherr, C.J.5
-
21
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
Kingsley, D. M. 1994. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8:133-146.
-
(1994)
Genes Dev.
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
22
-
-
0027318843
-
Negative regulation of G1 in mammalian cells: Inhibition of cyclin E-dependent kinase by TGF-β
-
Koff, A., M. Ohtsuki, K. Polyak, J. M. Roberts, and J. Massagué. 1993. Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-β. Science 260:536-539.
-
(1993)
Science
, vol.260
, pp. 536-539
-
-
Koff, A.1
Ohtsuki, M.2
Polyak, K.3
Roberts, J.M.4
Massagué, J.5
-
23
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
-
Kretzschmar, M., J. Doody, and J. Massagué. 1997. Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1. Nature 389:618-622.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massagué, J.3
-
24
-
-
0025326725
-
Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation
-
Laiho, M., J. A. DeCaprio, J. W. Ludlow, D. M. Livingston, and J. Massagué. 1990. Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation. Cell 62:175-185.
-
(1990)
Cell
, vol.62
, pp. 175-185
-
-
Laiho, M.1
DeCaprio, J.A.2
Ludlow, J.W.3
Livingston, D.M.4
Massagué, J.5
-
25
-
-
0028898203
-
Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect
-
Li, C. Y., L. Suardet, and J. B. Little. 1995. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J. Biol. Chem. 270:4971-4974.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4971-4974
-
-
Li, C.Y.1
Suardet, L.2
Little, J.B.3
-
26
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
Lundberg, A. S., and R. A. Weinberg. 1998. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol. 18:753-761.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 753-761
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
28
-
-
0030604542
-
TGF-β signaling: Receptors, transducers, and Mad proteins
-
Massagué, J. 1996. TGF-β signaling: receptors, transducers, and Mad proteins. Cell 85:947-950.
-
(1996)
Cell
, vol.85
, pp. 947-950
-
-
Massagué, J.1
-
29
-
-
0028268284
-
D-type cyclin-dependent kinase activity in mammalian cells
-
Matsushime, H., D. E. Quelle, S. A. Shurtleff, M. Shibuya, C. J. Sherr, and J. Y. Kato. 1994. D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol. 14:2066-2076.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2066-2076
-
-
Matsushime, H.1
Quelle, D.E.2
Shurtleff, S.A.3
Shibuya, M.4
Sherr, C.J.5
Kato, J.Y.6
-
30
-
-
0025987535
-
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast
-
Millar, J. B., C. H. McGowan, G. Lenaers, R. Jones, and P. Russell. 1991. p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J. 10:4301-4309.
-
(1991)
EMBO J.
, vol.10
, pp. 4301-4309
-
-
Millar, J.B.1
McGowan, C.H.2
Lenaers, G.3
Jones, R.4
Russell, P.5
-
31
-
-
0025824738
-
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
-
Montesano, R., K. Matsumoto, T. Nakamura, and L. Orci. 1991. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67:901-908.
-
(1991)
Cell
, vol.67
, pp. 901-908
-
-
Montesano, R.1
Matsumoto, K.2
Nakamura, T.3
Orci, L.4
-
32
-
-
0028931265
-
Principles of CDK regulation
-
Morgan, D. O. 1995. Principles of CDK regulation. Nature 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
33
-
-
0030714114
-
Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin/Cdk2 complexes
-
Müller, D., C. Bouchard, B. Rudolph, P. Steiner, I. Stuckmann, R. Saffrich, W. Ansorge, W. Huttner, and M. Eilers. 1997. Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin/Cdk2 complexes. Oncogene 15:2561-2576.
-
(1997)
Oncogene
, vol.15
, pp. 2561-2576
-
-
Müller, D.1
Bouchard, C.2
Rudolph, B.3
Steiner, P.4
Stuckmann, I.5
Saffrich, R.6
Ansorge, W.7
Huttner, W.8
Eilers, M.9
-
34
-
-
0030010591
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
35
-
-
0027193034
-
Cyclin-dependent regulation of G1 in mammalian fibroblasts
-
Ohtsubo, M., and J. M. Roberts. 1993. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259:1908-1912.
-
(1993)
Science
, vol.259
, pp. 1908-1912
-
-
Ohtsubo, M.1
Roberts, J.M.2
-
37
-
-
0028828204
-
Cyclins and cyclin-dependent kinases: Theme and variations
-
Pines, J. 1995. Cyclins and cyclin-dependent kinases: theme and variations. Adv. Cancer Res. 66:181-212.
-
(1995)
Adv. Cancer Res.
, vol.66
, pp. 181-212
-
-
Pines, J.1
-
38
-
-
0028179669
-
Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
-
Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8:9-22.
-
(1994)
Genes Dev.
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.V.2
Solomon, M.J.3
Sherr, C.J.4
Massagué, J.5
Roberts, J.M.6
Koff, A.7
-
39
-
-
0028176483
-
Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massagué, J.7
-
40
-
-
0030614715
-
Kip1 coordinate their inhibitory interactions with Cdk4 and Cdk2
-
Kip1 coordinate their inhibitory interactions with Cdk4 and Cdk2. Genes Dev. 11:492-503.
-
(1997)
Genes Dev.
, vol.11
, pp. 492-503
-
-
Reynisdóttir, I.1
Massagué, J.2
-
41
-
-
0029153609
-
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
-
Reynisdóttir, I., K. Polyak, A. Iavarone, and J. Massagué. 1995. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev. 9:1831-1845.
-
(1995)
Genes Dev.
, vol.9
, pp. 1831-1845
-
-
Reynisdóttir, I.1
Polyak, K.2
Iavarone, A.3
Massagué, J.4
-
43
-
-
0030974040
-
INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells
-
INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells. Mol. Cell. Biol. 17:2458-2467.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2458-2467
-
-
Sandhu, C.1
Garbe, J.2
Bhattacharya, N.3
Daksis, J.4
Pan, C.-H.5
Yaswen, P.6
Koh, J.7
Slingerland, J.M.8
Stampfer, M.R.9
-
44
-
-
0029849620
-
Cancer cell cycles
-
Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
45
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
Sherr, C. J. 1994. G1 phase progression: cycling on cue. Cell 79:551-555.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
46
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr, C. J., and J. M. Roberts. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9:1149-1163.
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
47
-
-
0028227197
-
A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells
-
Slingerland, J. M., L. Hengst, C. H. Pan, D. Alexander, M. R. Stampfer, and S. I. Reed. 1994. A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells. Mol. Cell. Biol. 14:3683-3694.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3683-3694
-
-
Slingerland, J.M.1
Hengst, L.2
Pan, C.H.3
Alexander, D.4
Stampfer, M.R.5
Reed, S.I.6
-
48
-
-
0027007963
-
Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase
-
Solomon, M. J., T. Lee, and M. W. Kirschner. 1992. Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol. Biol. Cell 3:13-27.
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 13-27
-
-
Solomon, M.J.1
Lee, T.2
Kirschner, M.W.3
-
49
-
-
0030049442
-
Hepatocyte growth factor releases epithelial and endothelial cells from growth arrest induced by transforming growth factor-β1
-
Taipale, J., and J. Keski-Oja. 1996. Hepatocyte growth factor releases epithelial and endothelial cells from growth arrest induced by transforming growth factor-β1. J. Biol. Chem. 271:4342-4348.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4342-4348
-
-
Taipale, J.1
Keski-Oja, J.2
-
50
-
-
0031684855
-
Extracellular matrix associated transforming growth factor-β: Role in cancer cell growth and invasion
-
Taipale, J., J. Saharinen, and J. Keski-Oja. 1998. Extracellular matrix associated transforming growth factor-β: role in cancer cell growth and invasion. Adv. Cancer Res. 75:87-133.
-
(1998)
Adv. Cancer Res.
, vol.75
, pp. 87-133
-
-
Taipale, J.1
Saharinen, J.2
Keski-Oja, J.3
-
52
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
53
-
-
0030918714
-
Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases
-
Zarkowska, T., and S. Mittnacht. 1997. Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. J. Biol. Chem. 272:12738-12746.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12738-12746
-
-
Zarkowska, T.1
Mittnacht, S.2
-
55
-
-
0028983384
-
Cip1-related domain to bind cyclin/Cdk2 and regulate interactions with E2F
-
Cip1-related domain to bind cyclin/Cdk2 and regulate interactions with E2F. Genes Dev. 9:1740-1752.
-
(1995)
Genes Dev.
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
|