-
1
-
-
0028884033
-
PD098059 is a specific inhibitor of the activation of MAP kinase kinase in vitro and in vivo
-
Alessi, D. R., A. Cuenda, P. Cohen, D. T. Dudley, and A. R. Saltiel. 1995. PD098059 is a specific inhibitor of the activation of MAP kinase kinase in vitro and in vivo. J. Biol. Chem. 270:27489-27494.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
2
-
-
0025285159
-
Ras oncogenes: Their role in neoplasia
-
Barbacid, M. 1990. Ras oncogenes: their role in neoplasia. Eur. J. Clin. Investig. 20:225-235.
-
(1990)
Eur. J. Clin. Investig.
, vol.20
, pp. 225-235
-
-
Barbacid, M.1
-
3
-
-
0027170920
-
SH3 domains direct cellular localization of signaling molecules
-
Bar-Sagi, D., D. Rotin, A. Batzer, V. Mandiyan, and J. Schlessinger. 1993. SH3 domains direct cellular localization of signaling molecules. Cell 74:83-91.
-
(1993)
Cell
, vol.74
, pp. 83-91
-
-
Bar-Sagi, D.1
Rotin, D.2
Batzer, A.3
Mandiyan, V.4
Schlessinger, J.5
-
4
-
-
0033621780
-
P27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
-
Boussiotis, V. A., G. J. Freeman, P. A. Taylor, A. Berezovskaya, I. Grass, B. R. Blazar, and L. M. Nadler. 2000. P27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat. Med. 6:290-296.
-
(2000)
Nat. Med.
, vol.6
, pp. 290-296
-
-
Boussiotis, V.A.1
Freeman, G.J.2
Taylor, P.A.3
Berezovskaya, A.4
Grass, I.5
Blazar, B.R.6
Nadler, L.M.7
-
5
-
-
0028857006
-
Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos
-
Buday, L., P. H. Warne, and J. Downward. 1995. Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos. Oncogene 11: 1327-1331.
-
(1995)
Oncogene
, vol.11
, pp. 1327-1331
-
-
Buday, L.1
Warne, P.H.2
Downward, J.3
-
7
-
-
0027304731
-
Human Sos1: A guanine nucleotide exchange factor for Ras that binds to GRB2
-
Chardin, P., J. H. Camonis, N. W. Gale, L. Van Aelst, J. Schlessinger, M. H. Wigler, and D. Bar-Sagi. 1993. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science 260:1338-1343.
-
(1993)
Science
, vol.260
, pp. 1338-1343
-
-
Chardin, P.1
Camonis, J.H.2
Gale, N.W.3
Van Aelst, L.4
Schlessinger, J.5
Wigler, M.H.6
Bar-Sagi, D.7
-
8
-
-
0032438571
-
Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
-
Cheng, A. M., T. M. Saxton, R. Sakai, S. Kulkarni, G. Mbamalu, W. Vogel, C. G. Tortorice, R. D. Cardiff, J. C. Cross, W. J. Muller, and T. Pawson. 1998. Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. Cell 95:793-803.
-
(1998)
Cell
, vol.95
, pp. 793-803
-
-
Cheng, A.M.1
Saxton, T.M.2
Sakai, R.3
Kulkarni, S.4
Mbamalu, G.5
Vogel, W.6
Tortorice, C.G.7
Cardiff, R.D.8
Cross, J.C.9
Muller, W.J.10
Pawson, T.11
-
11
-
-
0000856039
-
Cell cycle control: An overview
-
B. Vogelstein and K. W. Kinzler (ed.), McGraw-Hill, New York, N.Y.
-
Clurman, B., and J. M. Roberts. 1998. Cell cycle control: an overview, p. 175-193. In B. Vogelstein and K. W. Kinzler (ed.), The genetic basis of human cancer, 1st ed. McGraw-Hill, New York, N.Y.
-
(1998)
The Genetic Basis of Human Cancer, 1st Ed.
, pp. 175-193
-
-
Clurman, B.1
Roberts, J.M.2
-
13
-
-
0033602278
-
Kip1-deficient cells
-
Kip1-deficient cells. Curr. Biol. 9:163-173.
-
(1999)
Curr. Biol.
, vol.9
, pp. 163-173
-
-
Coats, S.1
Whyte, P.2
Fero, M.L.3
Lacy, S.4
Chung, G.5
Randel, E.6
Firpo, E.7
Roberts, J.M.8
-
14
-
-
0029791452
-
Identification of the MAP kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2
-
Corbolan-Garcia, S., S.-S. Yang, K. R. Degenhardt, and D. Bar-Sagi. 1996. Identification of the MAP kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2. Mol. Cell. Biol. 10:5674-5682.
-
(1996)
Mol. Cell. Biol.
, vol.10
, pp. 5674-5682
-
-
Corbolan-Garcia, S.1
Yang, S.-S.2
Degenhardt, K.R.3
Bar-Sagi, D.4
-
15
-
-
0027934898
-
Overexpression of the Grb2 gene in human breast cancer cell lines
-
Daly, R. J., M. D. Binder, and R. L. Sutherland. 1994. Overexpression of the Grb2 gene in human breast cancer cell lines. Oncogene 9:2723-2727.
-
(1994)
Oncogene
, vol.9
, pp. 2723-2727
-
-
Daly, R.J.1
Binder, M.D.2
Sutherland, R.L.3
-
18
-
-
0029166667
-
A synthetic inhibitor of the MAP kinase cascade
-
Dudley, D. T., L. Pang, S. J. Decker, A. J. Bridges, and A. R. Saltiel. 1995. A synthetic inhibitor of the MAP kinase cascade. Proc. Natl. Acad. Sci. USA 92:7686-7689.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
19
-
-
0027910431
-
Association of SOS Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
-
Egan, S. E., B. W. Giddings, M. W. Brooks, L. Buday, A. M. Sizeland, and R. A. Weinberg. 1993. Association of SOS Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363:45-51.
-
(1993)
Nature
, vol.363
, pp. 45-51
-
-
Egan, S.E.1
Giddings, B.W.2
Brooks, M.W.3
Buday, L.4
Sizeland, A.M.5
Weinberg, R.A.6
-
20
-
-
0033628672
-
Relationship between Ras pathways and cell cycle control
-
Ewen, M. E. 2000. Relationship between Ras pathways and cell cycle control. Progress Cell Cycle Res. 4:1-17.
-
(2000)
Progress Cell Cycle Res.
, vol.4
, pp. 1-17
-
-
Ewen, M.E.1
-
21
-
-
15844384256
-
Kip1-deficient mice
-
Kip1-deficient mice. Cell 85:733-744.
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.8
Broudy, V.9
Perlmutter, R.M.10
Kaushansky, K.11
Roberts, J.M.12
-
23
-
-
0034002461
-
Integration of positive and negative growth signals during ras pathway activation in vivo
-
Frame, S., and A. Balmain. 2000. Integration of positive and negative growth signals during ras pathway activation in vivo. Curr. Opin. Genet. Dev. 10: 106-113.
-
(2000)
Curr. Opin. Genet. Dev.
, vol.10
, pp. 106-113
-
-
Frame, S.1
Balmain, A.2
-
24
-
-
0030947356
-
kip1 and degree of malignancy in human breast and colorectal cancers
-
kip1 and degree of malignancy in human breast and colorectal cancers. Proc. Natl. Acad. Sci. USA 94:6380-6385.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6380-6385
-
-
Fredersdorf, S.1
Burns, J.2
Milne, A.M.3
Packham, G.4
Fallis, L.5
Gillett, C.E.6
Royds, J.A.7
Peston, D.8
Hall, P.A.9
Hanby, A.M.10
Barnes, D.M.11
Shousha, S.12
O'Hare, M.J.13
Lu, X.14
-
26
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
27
-
-
0032875460
-
Mechanism of action and in vivo role of PDGF
-
Heldin, C., and B. Westermark. 1999. Mechanism of action and in vivo role of PDGF. Phys. Rev. 79:1283-1316.
-
(1999)
Phys. Rev.
, vol.79
, pp. 1283-1316
-
-
Heldin, C.1
Westermark, B.2
-
28
-
-
0028275998
-
A cell cycle-regulated inhibitor of cyclin-dependent kinases
-
Hengst, L., V. Dulic, J. M. Slingerland, E. Lees, and S. I. Reed. 1994. A cell cycle-regulated inhibitor of cyclin-dependent kinases. Proc. Natl. Acad. Sci. USA 91:5291-5295.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5291-5295
-
-
Hengst, L.1
Dulic, V.2
Slingerland, J.M.3
Lees, E.4
Reed, S.I.5
-
32
-
-
0031043776
-
Signal transduction from multiple Ras effectors
-
Katz, M. E., and F. McCormick. 1997. Signal transduction from multiple Ras effectors. Curr. Opin. Genet. Dev. 7:75-79.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 75-79
-
-
Katz, M.E.1
McCormick, F.2
-
33
-
-
15844415946
-
Kip1
-
Kip1. Cell 85:721-732.
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
34
-
-
0027318843
-
1 in mammalian cells: Inhibition of cyclin E-dependent kinase by transforming growth factor beta
-
1 in mammalian cells: inhibition of cyclin E-dependent kinase by transforming growth factor beta. Science 260:536-539.
-
(1993)
Science
, vol.260
, pp. 536-539
-
-
Koff, A.1
Ohtsuki, M.2
Polyack, K.3
Roberts, J.4
Massague, J.5
-
35
-
-
0030973878
-
New functional activities for the p21 family of inhibitors
-
LaBaer, J., M. D. Garrett, L. F. Stevenson, J. M. Slingerland, C. Sandhu, H. S. Chou, A. Fattaey, and E. Harlow. 1997. New functional activities for the p21 family of inhibitors. Genes Dev. 11:847-862.
-
(1997)
Genes Dev.
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
Chou, H.S.6
Fattaey, A.7
Harlow, E.8
-
36
-
-
0031741554
-
Regulation of exit from quiescence by p27 and cyclin D1-CDK4
-
Ladha, M. H., K. Y. Lee, T. M. Upton, M. F. Reed, and M. E. Ewen. 1998. Regulation of exit from quiescence by p27 and cyclin D1-CDK4. Mol. Cell. Biol. 18:6605-6615.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6605-6615
-
-
Ladha, M.H.1
Lee, K.Y.2
Upton, T.M.3
Reed, M.F.4
Ewen, M.E.5
-
39
-
-
0027312272
-
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling
-
Li, N., A. Batzer, R. Daly, V. Yajkik, E. Skolnik, P. Chardin, D. Bar-Sagi, B. Margolis, and J. Schlessinger. 1993. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature 363:85-88.
-
(1993)
Nature
, vol.363
, pp. 85-88
-
-
Li, N.1
Batzer, A.2
Daly, R.3
Yajkik, V.4
Skolnik, E.5
Chardin, P.6
Bar-Sagi, D.7
Margolis, B.8
Schlessinger, J.9
-
41
-
-
0026729382
-
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
-
Lowenstein, E. J., R. J. Daly, A. G. Batzer, W. Li, B. Margolis, R. Lammers, A. Ullrich, E. Y. Skolnik, D. Bar-Sagi, and J. Schlessinger. 1992. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell 70:431-442.
-
(1992)
Cell
, vol.70
, pp. 431-442
-
-
Lowenstein, E.J.1
Daly, R.J.2
Batzer, A.G.3
Li, W.4
Margolis, B.5
Lammers, R.6
Ullrich, A.7
Skolnik, E.Y.8
Bar-Sagi, D.9
Schlessinger, J.10
-
42
-
-
0028141496
-
Transformation of mammalian cells by consitutively active MAP kinase kinase
-
Mansour, S. J., W. T. Matten, A. S. Hermann, J. M. Candia, S. Rong, K. Fukasawa, G. F. VandeWoude, and N. G. Ahn. 1994. Transformation of mammalian cells by consitutively active MAP kinase kinase. Science 265: 966-970.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
VandeWoude, G.F.7
Ahn, N.G.8
-
43
-
-
0031466305
-
Cyclin-dependent kinases: Engines, clocks, and microprocessors
-
Morgan, D. O. 1997. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13:261-291.
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
44
-
-
0021970413
-
Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
-
Mulcahy, L. S., M. R. Smith, and D. W. Stacey. 1985. Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells. Nature 313:241-243.
-
(1985)
Nature
, vol.313
, pp. 241-243
-
-
Mulcahy, L.S.1
Smith, M.R.2
Stacey, D.W.3
-
45
-
-
0030714114
-
CDK2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclinE/cdk2 complexes
-
Muller, D., C. Bouchard, B. Rudolph, P. Steiner, I. Stuckmann, R. Saffrich, W. Ansorge, W. Huttner, and M. Eilers. 1997. CDK2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclinE/cdk2 complexes. Oncogene 15:2561-2576.
-
(1997)
Oncogene
, vol.15
, pp. 2561-2576
-
-
Muller, D.1
Bouchard, C.2
Rudolph, B.3
Steiner, P.4
Stuckmann, I.5
Saffrich, R.6
Ansorge, W.7
Huttner, W.8
Eilers, M.9
-
46
-
-
0030010591
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
47
-
-
0028172867
-
kip1 cyclin-CDK kinase inhibitor prevented by rapamycin
-
kip1 cyclin-CDK kinase inhibitor prevented by rapamycin. Nature 372:570-573.
-
(1994)
Nature
, vol.372
, pp. 570-573
-
-
Nourse, J.1
Firpo, E.2
Flanagan, M.3
Meyerson, M.4
Polyak, K.5
Lee, M.H.6
Massague, J.7
Crabtree, G.8
Roberts, J.9
-
48
-
-
0027468233
-
A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of ras guanine nucleotide exchange
-
Olivier, J. P., T. Raabe, M. Henkenmeyer, B. Dickson, G. Mbamalu, B. Margolis, J. Schlessinger, E. Hafen, and T. Pawson. 1993. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of ras guanine nucleotide exchange, Sos. Cell 73:179-191.
-
(1993)
Sos. Cell
, vol.73
, pp. 179-191
-
-
Olivier, J.P.1
Raabe, T.2
Henkenmeyer, M.3
Dickson, B.4
Mbamalu, G.5
Margolis, B.6
Schlessinger, J.7
Hafen, E.8
Pawson, T.9
-
49
-
-
0029024015
-
Role of the ubiquitinproteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano, M., S. W. Tam, A. M. Theodoras, P. Beer-Romero, G. Del Sal, V. Chau, P. R. Yew, G. F. Draetta, and M. Rolfe. 1995. Role of the ubiquitinproteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269:682-685.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
50
-
-
0030941460
-
Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein
-
Peeper, D. S., T. M. Upton, M. H. Ladha, E. Neuman, J. Zalvide, R. Bernards, J. A. DeCaprio, and M. E. Ewen: 1997. Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein. Nature 386:177-181.
-
(1997)
Nature
, vol.386
, pp. 177-181
-
-
Peeper, D.S.1
Upton, T.M.2
Ladha, M.H.3
Neuman, E.4
Zalvide, J.5
Bernards, R.6
DeCaprio, J.A.7
Ewen, M.E.8
-
51
-
-
0028176483
-
Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
52
-
-
0028179669
-
kip1, a cyclin-CDK inhibitor, links transforming growth factor beta and contact inhibition to cell cycle arrest
-
kip1, a cyclin-CDK inhibitor, links transforming growth factor beta and contact inhibition to cell cycle arrest. Genes Dev. 8:9-22.
-
(1994)
Genes Dev.
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.2
Solomon, M.J.3
Sherr, C.J.4
Massague, J.5
Roberts, J.M.6
Koff, A.7
-
53
-
-
0035803593
-
p27 cytoplasmic localization is regulated by phosphorylation on Ser 10 and is not a prerequisite for its proteolysis
-
Rodier, G., A. Montagnoli, L. Di Marcotullio, P. Coulombe, G. F. Draetta, M. Pagano, and S. Meloche. 2001. p27 cytoplasmic localization is regulated by phosphorylation on Ser 10 and is not a prerequisite for its proteolysis. EMBO J. 20:6672-6682.
-
(2001)
EMBO J.
, vol.20
, pp. 6672-6682
-
-
Rodier, G.1
Montagnoli, A.2
Di Marcotullio, L.3
Coulombe, P.4
Draetta, G.F.5
Pagano, M.6
Meloche, S.7
-
54
-
-
0026678172
-
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
-
Rozakis-Adcock, M., J. McGlade, G. Mbamalu, G. Pelicci, R. Daly, W. Li, A. Batzer, S. Thomas, J. Brugge, P. G. Pelicci, J. Schlessinger, and T. Pawson. 1992. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature 360:689-692.
-
(1992)
Nature
, vol.360
, pp. 689-692
-
-
Rozakis-Adcock, M.1
McGlade, J.2
Mbamalu, G.3
Pelicci, G.4
Daly, R.5
Li, W.6
Batzer, A.7
Thomas, S.8
Brugge, J.9
Pelicci, P.G.10
Schlessinger, J.11
Pawson, T.12
-
55
-
-
0344731443
-
Anomalous high p27/KIP1 expression in a subset of aggressive B-cell lymphomas is associated with cyclin D3 overexpression. p27/KIP1-cyclin D3 colocalization in tumor cells
-
Sanchez-Beato, M., F. I. Camacho, J. C. Martinez-Montero, A. I. Saez, R. Villuendas, L. Sanchez-Verde, J. F. Garcia, and M. A. Piris. 1999. Anomalous high p27/KIP1 expression in a subset of aggressive B-cell lymphomas is associated with cyclin D3 overexpression. p27/KIP1-cyclin D3 colocalization in tumor cells. Blood 94:765-772.
-
(1999)
Blood
, vol.94
, pp. 765-772
-
-
Sanchez-Beato, M.1
Camacho, F.I.2
Martinez-Montero, J.C.3
Saez, A.I.4
Villuendas, R.5
Sanchez-Verde, L.6
Garcia, J.F.7
Piris, M.A.8
-
56
-
-
0025337018
-
Platelet-derived growth factor stimulates formation of active p21ras-GTP complex in Swiss mouse 3T3 cells
-
Satoh, T., M. Endo, M. Nakafuku, S. Nakamura, and Y. Kaziro. 1990. Platelet-derived growth factor stimulates formation of active p21ras-GTP complex in Swiss mouse 3T3 cells. Proc. Natl. Acad. Sci. USA 87:5993-5997.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5993-5997
-
-
Satoh, T.1
Endo, M.2
Nakafuku, M.3
Nakamura, S.4
Kaziro, Y.5
-
57
-
-
0025195107
-
Accumulation of p21ras-GTP in response to stimulation with EGF and oncogene products with tyrosine kinase activity
-
Satoh, T., M. Endo, M. Nakafuku, T. Akiyama, T. Yamamoto, and Y. Kaziro. 1990. Accumulation of p21ras-GTP in response to stimulation with EGF and oncogene products with tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 87:7926-7929.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7926-7929
-
-
Satoh, T.1
Endo, M.2
Nakafuku, M.3
Akiyama, T.4
Yamamoto, T.5
Kaziro, Y.6
-
63
-
-
0034175984
-
Understanding Ras: 'It ain't over 'til it's over'
-
Shields, J. M., K. Pruitt, A. McFall, A. Shaub, and C. J. Der. 2000. Understanding Ras: 'it ain't over 'til it's over'. Trends Cell Biol. 10:147-154.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 147-154
-
-
Shields, J.M.1
Pruitt, K.2
McFall, A.3
Shaub, A.4
Der, C.J.5
-
64
-
-
0027404990
-
Ras1 activation and binds to sevenless and Sos protein in vitro
-
Ras1 activation and binds to sevenless and Sos protein in vitro. Cell 73:169-177.
-
(1993)
Cell
, vol.73
, pp. 169-177
-
-
Simon, M.A.1
Dodson, G.S.2
Rubin, G.M.3
-
65
-
-
0032522414
-
Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma
-
Singh, S. P., J. Lipman, H. Goldman, F. H. Ellis, Jr, L. Aizenman, M. G. Cangi, S. Signoretti, D. S. Chiaur, M. Pagano, and M. Loda. 1998. Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma. Cancer Res. 58:1730-1735.
-
(1998)
Cancer Res.
, vol.58
, pp. 1730-1735
-
-
Singh, S.P.1
Lipman, J.2
Goldman, H.3
Ellis F.H., Jr.4
Aizenman, L.5
Cangi, M.G.6
Signoretti, S.7
Chiaur, D.S.8
Pagano, M.9
Loda, M.10
-
66
-
-
0033912083
-
Characterization and targeted disruption of murine Nup50, a p27(Kip1)interacting component of the nuclear pore complex
-
Smitherman, M., K. Lee, J. Swanger, R. Kapur, and B. E. Clurman. 2000. Characterization and targeted disruption of murine Nup50, a p27(Kip1)interacting component of the nuclear pore complex. Mol. Cell. Biol. 20: 5631-5642.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5631-5642
-
-
Smitherman, M.1
Lee, K.2
Swanger, J.3
Kapur, R.4
Clurman, B.E.5
-
69
-
-
0030740210
-
Kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
-
Kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell. Biol. 17:5348-5358.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5348-5358
-
-
Takuwa, N.1
Takuwa, Y.2
-
70
-
-
0030461098
-
Cell cycle-dependent activation of Ras
-
Taylor, S. J., and D. Shalloway. 1996. Cell cycle-dependent activation of Ras. Curr. Biol. 6:1621-1627.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1621-1627
-
-
Taylor, S.J.1
Shalloway, D.2
-
72
-
-
0028363519
-
1-cyclin-CDK protein kinase activity, is related to p21
-
1-cyclin-CDK protein kinase activity, is related to p21. Cell 78:67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
73
-
-
0032980308
-
The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
-
Tsihlias, J., L. Kapusta, and J. Slingerland. 1999. The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Annu. Rev. Med. 50:401-423.
-
(1999)
Annu. Rev. Med.
, vol.50
, pp. 401-423
-
-
Tsihlias, J.1
Kapusta, L.2
Slingerland, J.3
-
74
-
-
0030867556
-
Grb2 overexpression in nuclei and cytoplasm of human breast cells: A histochemical and biochemical study of normal and neoplastic mammary tissue specimens
-
Verbeek, B. S., S. S. Adriaansen-Slot, G. Rijksen, and T. M. Vroom. 1997. Grb2 overexpression in nuclei and cytoplasm of human breast cells: a histochemical and biochemical study of normal and neoplastic mammary tissue specimens. J. Pathol. 183:195-203.
-
(1997)
J. Pathol.
, vol.183
, pp. 195-203
-
-
Verbeek, B.S.1
Adriaansen-Slot, S.S.2
Rijksen, G.3
Vroom, T.M.4
-
75
-
-
0030847760
-
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
-
Vlach, J., S. Hennecke, and B. Amati. 1997. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J. 16:5334-5344.
-
(1997)
EMBO J.
, vol.16
, pp. 5334-5344
-
-
Vlach, J.1
Hennecke, S.2
Amati, B.3
-
76
-
-
0028950637
-
Insulin-stimulated dissociation of the Sos-Grb2 complex
-
Waters, S. B., K. Yamauchi, and J. E. Pessin. 1995. Insulin-stimulated dissociation of the Sos-Grb2 complex. Mol. Cell. Biol. 15:2791-2799.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2791-2799
-
-
Waters, S.B.1
Yamauchi, K.2
Pessin, J.E.3
-
77
-
-
0034735893
-
The isoform-specific stretch of hSos1 defines a new Grb2-binding domain
-
Zarich, N., J. L. Oliva, R. Jorge, E. Santos, and J. M. Rojas. 2000. The isoform-specific stretch of hSos1 defines a new Grb2-binding domain. Oncogene 19:5872-5883.
-
(2000)
Oncogene
, vol.19
, pp. 5872-5883
-
-
Zarich, N.1
Oliva, J.L.2
Jorge, R.3
Santos, E.4
Rojas, J.M.5
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