The cytoplasmic shuttling and subsequent degradation of p27 Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex

Journal of Biological Chemistry

Volumn 277, Issue 3, 2002, Pages 2302-2310

  Tomoda, Kiichiro ^a   Kubota, Yukiko ^a   Arata, Yukinobu ^a   Mori, Seiji ^a   Maeda, Maki ^a   Tanaka, Toshiaki ^a   Yoshida, Minoru ^a   Yoneda Kato, Noriko ^a   Kato, Jun Ya ^a,b  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASMIC SHUTTLING;

CELL CULTURE; DEGRADATION; GLYCEROL; MUTAGENESIS; ORGANIC ACIDS; PROTEINS;

BIOCHEMISTRY;

ALANINE; ASPARAGINE; ASPARTIC ACID; CELL PROTEIN; COP9 SIGNALOSOME; CSN5 PROTEIN; JAB1 PROTEIN; LEPTOMYCIN B; LEUCINE; PROTEIN P27; SIGNALOSOME; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL CYCLE; CELL GROWTH; CELL NUCLEUS; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FIBROBLAST; GROWTH INHIBITION; INTRACELLULAR TRANSPORT; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TRANSPORT;

3T3 CELLS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CELL NUCLEUS; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOPLASM; DNA-BINDING PROTEINS; HYDROLYSIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; NES;

EID: 0037127256     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104431200     Document Type: Article

References (54)